Clinical trials: Prebiotic
Overweight
The Efficacy on Overweight With Oral Supplemenation of Probiotics and Prebiotics
The goal of this interventional study is to evaluate the efficacy of probiotics with prebiotics on overweight. 200 eligible participants with overweight will be enrolled and randomized to consume four study products for 3 months.
- Trial name
- NCT05710055
- Testing
- Study product A (Wonderlab wonder4shape), Study product B (Wonderlab wonder4shape), Study product C (Wonderlab wonder4shape)
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shenzhen Precision Health Food Technology Co. Ltd.,
Prebiotics Effect
Prebiotics Change Microflora and Decrease LPS
The purpose of the present study was to establish the prebiotic effect of a new xylo-oligosaccharides (XOS) and of an inulin-and-XOS mixture (INU-XOS) and to determine their effect on endotoxaemia (lipopolysaccharides (LPS)) and…
- Trial name
- PIB (NCT02287844)
- Testing
- XOS, INU-XOS
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Healthy Gut Microbiota
Human Gut Microbiota and Prebiotic Response
This study is designed to examine the shift in gut microbiota and their metabolism after consumption of a dietary supplement (prebiotic) by healthy participants.
- Trial name
- NCT03595306
- Testing
- Prebiotic A - inulin, Prebiotic B - galactooligosaccharides(GOS), Prebiotic C - wheat dextrin
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Duke University
Irritable Bowel Syndrome, Diarrhea- Irritable Bowel Syndrome
To Study the Effect of Short-chain Fructooligosaccharides in Women With Irritable Bowel Syndrome
To evaluate whether there is clinical improvement through the scales (Bristol, IBS severity score, and IBS quality of life) in women with irritable bowel syndrome after administration of SC-FOS (short-chain…
- Conditions
- Irritable Bowel Syndrome, Diarrhea- Irritable Bowel Syndrome, Constipation-predominant Irritable Bowel Syndrome
- Trial name
- NCT05941650
- Testing
- Short Chain Fructooligosaccharides, Corn Starch
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Chihuahua
Microbiota, Cognitive Change
Healthy Prebiotic and Postbiotic Effects of Peanuts and Peanut Butter: College Intervention Trial
Nuts have a prebiotic effect mainly due to their content of fiber and polyphenols, which provide substrates for the human gut microbiota.
- Trial name
- ARISTOTLE (NCT04324749)
- Testing
- Roasted peanuts (group A), Peanut butter (group B), Control (group C)
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Gut Health, Gastrointestinal Diseases
Improved Gut Health Outcomes Associated With Probiotics Fortified With Hydrolyzed Whey Protein in Infant Formula
The goal of this interventional clinical trial is to test the effectiveness of improving gut health in terms of frequency of bowel movements in newly born infants fed with Feihe investigational formula product containing…
- Trial name
- NCT06159088
- Testing
- Feihe Investigational Formula, Control Formula, Breastfeeding
- Where
- 3 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Heilongjiang Feihe Dairy Co. Ltd.
Human Gut Microbiota
Effects of Pre-, Pro- & Anti-biotics on Gut Microbiota
The purpose of this study is to compare and contrast the effects of a prebiotic (Trametes Versicolor), a probiotic (Saccharomyces boulardii) and an antibiotic (amoxicillin) on the gut microbiota of healthy volunteers.
- Trial name
- NCT01414010
- Testing
- Trametes versicolor extract, Saccharomyces boulardii, Amoxicillin
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Behavioral Measures of Tolerance
Nutritive Effects of Prebiotics on Early Postnatal Behavioral Measures of Tolerance
The study is intended to measure infant comfort, behavior, and sleep when consuming study formula with prebiotics compared to infants who consume a study formula without the prebiotics.
- Trial name
- NCT02118935
- Testing
- Previously marketed cow's mlik-based infant formula, Marketed cow's milk-based infant formula with prebiotics
- Where
- 7 sites in United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Healthy Subjects
The Critical Link Between Gut Microbiome Dysfunction, Cravings and Relapse: RECLAIM-GUT TRIAL
The human gut contains a vast community of microorganisms-including bacteria, viruses, and fungi-collectively known as the gut microbiota. This ecosystem co-evolves with humans and is shaped by diet, environment, and lifestyle.
- Trial name
- RECLAIM-GUT (NCT07350538)
- Testing
- Personalized prebiotic dietary Formulation 2, Personalized prebiotic dietary Formulation 3, Personalized prebiotic dietary Formulation 1
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Sleep
Evaluating the Effects of Prebiotics on Sleep, the Gut Microbiome, Cognition, Immune Function and Stress
The aim of the proposed randomised, double-blind, controlled, parallel groups trial is to assess the sleep, gut microbiome, cognitive, immune and stress effects of 56 days administration of three formulations of a prebiotic-based…
- Trial name
- NCT05239845
- Testing
- Prebiotic, Control
- Where
- 2 sites in United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Obesity
Effects of Prebiotic-based Snacks on the Gut Microbiota and Perceived 'Satisfaction'
To determine the effects of prebiotic 'snacks' on gut health and satisfaction between meals
- Trial name
- NutriSAT (NCT02041975)
- Testing
- Nutriose FB06
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Reading
Periodontal Diseases
The Role of Probiotics in Periodontal Disease
In this randomized controlled trial, it was aimed to evaluate the effect of probiotics (chewable tablets) and kefir consumption in the initial periodontal treatment of periodontitis patients on the change of oral microbiota and…
- Trial name
- tropipd (NCT05211219)
- Testing
- Probiotics, AOÇ Kefir, Food without additional food supplements
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gazi University
Physiological Stress, Cognitive Change
Effects of Prebiotics on Cognition and Health
This research intervention aims to examine the effects of prebiotic consumption on changes in behavioral and biological measures of cognition and stress among adults.
- Conditions
- Physiological Stress, Cognitive Change, Gastrointestinal Health
- Trial name
- EPOCH-2 (NCT04551937)
- Testing
- Lactose Free 1% Milk, Lactose Free 1% Milk + 10 g prebiotic
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Microbiome, Immune Function
The RAMP Study - Rejuvenation of the Aging Microbiota With Prebiotics
An individual's immune and metabolic status is coupled to consumed carbohydrates. Complex carbohydrates that are not digested by human enzymes may influence host biology by impacting microbiota composition and function, or act in…
- Conditions
- Microbiome, Immune Function, Inflammation
- Trial name
- RAMP (NCT03690999)
- Testing
- Prebiotic supplement
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Overweight
Long-term Effects of Arabinoxylans on Intestinal Barrier Function
The higher prevalence of overweight and obesity among the population contributes to increased incidences of chronic metabolic diseases.
- Trial name
- NCT01877044
- Testing
- NAXUS
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Dysbiosis
Effect of Peanut Butter on Gut and Metabolic Health
The goal of this is parallel arm, randomized clinical trial is to learn and understand the effect of daily smooth peanut butter consumption on gut and metabolic health of children age 6-13.
- Trial name
- NCT06916936
- Testing
- Creamy Richards 100% Peanuts! Creamy Natural Peanut Butter, Cadbury Milk Chocolate Spread
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida State University
Anemia, Iron-Deficiency
Iron Absorption From a Micronutrient Powder Containing Galacto-oligosaccharides (GOS)
Infants and young children in sub-Saharan Africa have high rates of iron deficiency anemia (IDA), which adversely affects their growth and cognitive development.
- Trial name
- FeGOS (NCT02666417)
- Testing
- Fortified maize porridge (MNP+iron), Fortified maize porridge (MNP+iron+GOS)
- Where
- Kenya
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Autism Spectrum Disorder, Anxiety
Open-label Pilot Study Synbiotic Treatment for Autism Spectrum Disorder
The objective of this study is to conduct a open-label pilot study evaluating the feasibility, tolerability and preliminary efficacy of a 12-week course of synbiotic in improving anxiety symptoms in children with ASD.
- Trial name
- NCT06126185
- Testing
- 12-week course of synbiotic
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Weight Loss, Metabolic Health
A Study to Evaluate a Supplement Combination in Supporting Weight Loss, Metabolic Health, and Quality of Life
This consumer-use study evaluates the effects of a combined postbiotic and prebiotic supplement regimen on appetite control, cravings, metabolic health, energy, and quality of life in adults aged 18-65 years with a body mass…
- Conditions
- Weight Loss, Metabolic Health, Quality of Life
- Trial name
- RESMRESG101 (NCT07608016)
- Testing
- Combination Prebiotic and Postbiotic
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Able Biolabs, LLC
Polyphenols, Obesity
Effect of a Low-calorie Diet With a Prebiotic Supplement on Health of Overweight-obese Subjects.
The main objective of this project is to evaluate the effect of prebiotic supplementation on weight loss and other physiological and metabolic parameters related to excess weight in overweight/obese adult men and women, as well…
- Conditions
- Polyphenols, Obesity, Weight Loss
- Trial name
- POSTBIOTICS (NCT06710106)
- Testing
- Prebiotic + hypocaloric diet
- Where
- Spain
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra