Clinical trials: Prediction Models
Liver Transplant Failure
Liver Graft Viability Assessment During Normothermic Regional Perfusion
With the increasing shortage of available donor organs, liver transplantation from donation after circulatory death (DCD) has been established in many countries to offer a therapeutic strategy for patients with end-stage liver…
- Trial name
- MAASTR3BOLOMIC (NCT05361044)
- Testing
- Blood samples Donnor
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Major Adverse Cardiac Events, Cerebrovascular Accident
Construction of a Prediction Model for MACCE in Elderly Patients After Elective Non-cardiac Surgery
Severe cardiovascular and cerebrovascular complications, including cardiac death, non-fatal angina/myocardial infarction, non-fatal heart failure, stroke, severe arrhythmia, etc., are one of the main types of postoperative…
- Conditions
- Major Adverse Cardiac Events, Cerebrovascular Accident, Postoperative Complications, Models
- Trial name
- NCT06391632
- Testing
- Revised Cardiac Risk Index
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Oncology
The Internal Prospective Validation of the Cancer Admission Score (CAS) Prediction Model
The goal of this single center prospective observational study is to determine the agreement between the cancer admission score (CAS) predicted disposition and the actual disposition in patients with an active cancer diagnosis…
- Trial name
- ONCOMING (NCT06558487)
- Testing
- Cancer Admission Score Prediction Model
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
Orthopedic Procedures, Pain, Postoperative
Risk Model for Severe Rebound Pain After Lower Limb Orthopedic Surgery Involving Single-Shot Sciatic Nerve Blocks
Rebound pain is a well-recognized phenomenon after the effects of a nerve block wear off. Severe rebound pain can happen after outpatient surgery, with patients often needing to come back to the hospital or use other health care…
- Conditions
- Orthopedic Procedures, Pain, Postoperative, Surgery, Nerve Block
- Trial name
- NCT05018104
- Testing
- This is not an interventional study
- Where
- Canada
- Volunteers
- 1,270 people
- Sponsor
- University of British Columbia
Heart Failure, Congestive
Validation of a Mortality Prediction Model for Acutely Decompensated Heart Failure Patients
The purpose of this protocol is to determine if the 3 variable mortality prediction model established using data from a retrospective, multi-center patient registry (The ADHERE Acute Decompensated HEart FailuRE National Registry)…
- Trial name
- NCT00536367
- Testing
- No intervention - observational study only
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Brian Hiestand MD
Lung Cancer
Formatting the Risk Prediction Models for Never-Smoking Lung Cancer
Lung Cancer is the leading cause of cancer-related deaths in Taiwan and worldwide and the incidence is also increasing. The payment for lung cancer which occupies the largest part of National Health Insurance expense is over 15…
- Trial name
- FORMOSA (NCT05572944)
- Testing
- LDCT lung cancer screen, immediately, LDCT lung cancer screen, later
- Where
- 7 sites in Taiwan
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Crohn's Disease, Intestinal Tuberculosis
Development of a Prediction Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease
The aim of this study is to develop a scoring system and a prediction model for differential diagnosis between intestinal tuberculosis and Crohn's disease.
- Trial name
- NCT01392365
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- Asan Medical Center
Sarcoma
Swiss Sarcoma Network: Prediction Model for Patient Selection in Sarcoma Care
The primary significance of this project is to perform a detailed analysis to assess the diagnostics, treatment and follow-up care, to develop a prediction model for future patient selection regarding various diagnostic and…
- Trial name
- NCT04300257
- Where
- 8 sites in Switzerland
- Volunteers
- 600 people
- Sponsor
- Kantonsspital Winterthur KSW
Preterm Birth, Preterm Labor
To Optimize Antenatal Management of Women With Pre Term Labor Using Amniocentesis
Implementation of prediction models of risk of spontaneous delivery within 7 days or of intra-amniotic infection in women with preterm labor and intact membranes
- Conditions
- Preterm Birth, Preterm Labor, Intra-amniotic Infection, Amniocentesis Affecting Fetus or Newborn
- Trial name
- OPTIM-PTL (NCT04831086)
- Testing
- Steroid Drug, Tocolytic Agents
- Where
- Spain
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Elective Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after elective surgery.
- Trial name
- NCT04929886
- Where
- 5 sites in China
- Volunteers
- 1,000,000 people
- Sponsor
- Huazhong University of Science and Technology
Gastric Cancer (Diagnosis), Postoperative Complications
DeepComp for Prediction of Gastric Cancer Postoperative Complications (DeepComp-Prospective)
Gastric cancer is a leading cause of cancer-related mortality, and radical surgery remains the primary treatment. However, postoperative complications are common and can significantly impact patient recovery and quality of life.
- Trial name
- NCT07401173
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Qun Zhao
Ischemic Stroke
Research on AIS Recurrence Risk Prediction Model Using XGBoost Combined With Convolutional Neural Network Algorithm
The purpose of this observational study is to construct a recurrence risk prediction model for ischemic stroke within 1, 3, 6, and 12 months using XGBoost combined with Convolutional Neural Network (CNN) algorithm.
- Trial name
- NCT06796283
- Where
- China
- Volunteers
- 2,628 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Fall, Fall Injury
A Clinical Decision Support System and Patient Portal for Preventing Medication-related Falls in Older Patients
Falls in older adults represents a growing public health challenge. The use of certain medication is recognized as an important modifiable risk factor for falls.
- Conditions
- Fall, Fall Injury, Fall Patients, Accidental Fall
- Trial name
- ADFICE_IT (NCT05449470)
- Testing
- CDSS, Patient Portal
- Where
- 10 sites in Netherlands
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pulmonary Nodules
Multicenter Prospective Validation of AI Models for Malignancy Risk Prediction in Pulmonary Nodules
This multicenter prospective diagnostic accuracy study will compare the performance of three artificial intelligence (AI) models (MVCS, LungDoc, and a United Imaging AI model) for predicting the malignancy risk of pulmonary…
- Trial name
- NCT07727122
- Where
- 5 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Myopia, Myopic Astigmatism
Machine Learning Prediction of 1-Year Refractive Error After SMILE
This retrospective single-center observational study is designed to develop and internally validate a multi-output machine learning model for predicting 1-year postoperative refractive prediction error after small incision…
- Conditions
- Myopia, Myopic Astigmatism, Refractive Error - Myopia Axial
- Trial name
- SMILE (NCT07478419)
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Tongji University
Pituitary Tumor
Construction and Application of a Risk Prediction Model Forepistaxis After Pituitary Tumor Resection
(1) Objective to establish an evaluation system for predicting the risk of epistaxis after endoscopic transsphenoidal pituitary surgery（ 2) Objective to determine the risk factors of epistaxis after endoscopic transsphenoidal…
- Trial name
- NCT04938401
- Volunteers
- 1 people
- Sponsor
- Wang Ying supervisor nurse
Trilaciclib, CDK4/6-dependent Solid Tumors
Trilaciclib in Combination With Chemotherapy in Patients With CDK4/6-Dependent Solid Tumors
Trilaciclib, an innovative first-in-class therapy that protects bone marrow at the source, has been approved for use in CDK4/6-independent small-cell lung cancer.
- Trial name
- NCT07490236
- Testing
- Trilaciclib group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Hebei Medical University Fourth Hospital
Chest X-ray for Clinical Evaluation
Feasibility of AI-based Heart Function Prediction Model Using CXR
The investigators will develop an artificial intelligence model to predict left ventricular ejection fraction using chest radiographic images and transthoracic echocardiography data.
- Trial name
- AI-CXR (NCT04996381)
- Testing
- Scanning Chest X-rays and performing AI algorithms on images
- Where
- South Korea
- Volunteers
- 505 people
- Sponsor
- Yonsei University
Coronary Heart Disease (CHD), Heart Failure
a Foundational Model for Cardiovascular Disease Diagnosis and Prediction
The goal of this observational study is to develop and evaluate the efficacy of a foundational model that integrates multimodal medical data to improve the diagnosis and prediction of cardiovascular diseases in patients aged 18…
- Conditions
- Coronary Heart Disease (CHD), Heart Failure, Arrhythmias, Valvular Heart Disease
- Trial name
- NCT06591923
- Testing
- No Interventions
- Where
- China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
The Focus is to Validate the Accuracy of a Non-invasive Artificial Intelligence Model for the Prediction of the Human Blastocyst Ploidy, Preimplantation Genetic Testing (PGT)
Evaluation of an Artificial Intelligence Model for the Prediction of Human Blastocyst Ploidy Without Invasive Procedures
The goal of this clinical trial is to evaluate an artificial intelligence model for the prediction of human blastocyst ploidy without invasive procedures in couples that receive preimplantation genetic testing.
- Trial name
- NCT06762704
- Testing
- Video recording
- Where
- 5 sites in China
- Volunteers
- 1,408 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School