Clinical trials: Prehospital Emergency
Prehospital
Pre-hospital Ultrasound Guided Peripheral Venous Catheter Insertion
This study evaluates two different techniques for ultrasound guided peripheral venous catheter insertion in pre-hospital emergency care in comparison with conventional approach without any ultrasound guidance.
- Trial name
- NCT03709394
- Testing
- Full utrasound guidance, Partial ultrasound guidance, No ultrasound guidance
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- Emergency Medical Service of the Central Bohemian Region, Czech Republic
Hemorrhage
Finnish Prehospital Whole Blood Study
Up-to-date evidence suggests that blood transfusion initiated as early as possible reduces the likelihood of death from hemorrhagic shock, and the sooner replacement therapy with blood products is initiated, the greater the…
- Trial name
- FinnPHWB (NCT05744583)
- Testing
- Packed red cell transfusion, Whole blood transfusion
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Finnish Red Cross Blood Service
Acute Pain Due to Trauma
Sublingual Versus Endovenous Fentanyl for the Prehospital Analgesia in Patients With Limb Trauma on the Slope
The purpose of this study is to determine the non-inferiority of the efficacy for prehospital analgesia of sublingual administered fentanyl versus endovenous administered fentanyl for patients with limb trauma on the slope
- Trial name
- NCT03080350
- Testing
- Fentanyl sublingual, Fentanyl ev
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- Azienda Sanitaria dell'Alto Adige
Telemedicine, Triage
Mobile Transmission of Prehospital Vital Signs to the Emergency Department
The purpose of this study is to examine if real time transmission of vital signs, ECG and chat communication between the prehospital ambulances and the emergency department has an effect on patient mortality, ICU admission…
- Conditions
- Telemedicine, Triage, Emergency Medical Service
- Trial name
- NCT02090452
- Testing
- Real time transmission of patient related data. Device used: MobiMed 3.1, manufactured by Ortivus AB Sweden
- Where
- 3 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Sepsis
Physician Administered Antibiotics in a Prehospital Setting
Sepsis is estimated to affect more than 30 million people globally. Detecting sepsis is notoriously difficult and there are no systems in place utilize prehospitally.
- Trial name
- PANTIPS (NCT03919851)
- Testing
- Antibiotics
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- Odense University Hospital
Hypotension and Shock, Wounds and Injuries
Prehospital Management of Hypotensive Trauma in HEMS
Up to today, inadequate evidences and knowledge exist about the best prehospital management of hypotensive trauma patients and its clinical consequence on the in-hospital recovery and mortality.
- Conditions
- Hypotension and Shock, Wounds and Injuries, Emergencies, Critical Care
- Trial name
- SPITFIRE (NCT04760977)
- Where
- 16 sites in Italy
- Volunteers
- 1,268 people
- Sponsor
- Azienda Usl di Bologna
Telemedicine, Emergency Medical Service
Audiovisual Consultations in Prehospital Emergency Care: Randomised Controlled Trial
This study investigates safety and efficacy of the use of audiovisual consultations of emergency medical service (EMS) doctor by paramedics for low urgency events in areas covered with paramedic crews only from emergency medical…
- Trial name
- Telemedicine (NCT04312321)
- Testing
- Mandatory phone call consultation, Mandatory audiovisual consultation
- Where
- Czechia
- Volunteers
- 600 people
- Sponsor
- Zdravotnicka Zachranna Sluzba Karlovarskeho Kraje, P.O.
Respiratory Failure
King Video Laryngoscope Versus Direct Laryngoscopy for Prehospital Intubation: A Randomized Controlled Trial
The goal of this study is to compare the first pass success rate of intubation between video assisted intubation and traditional direct visualization intubation in the field by Emergency Medical Service (EMS) professionals
- Trial name
- NCT02208349
- Testing
- King Video Laryngoscope, traditional direct laryngoscopy (DL)
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Saint Vincent Hospital, Pennsylvania
Stroke.
Prehospital Stroke Study at the Universitair Ziekenhuis Brussel I (PreSSUB I)
The PreSSUB trial I will focus on prehospital telemedicine for patients with suspicion of acute stroke. The study is designed as a prospective monocentric observational trial on the safety, feasibility and reliability of…
- Trial name
- PreSSUB I (NCT02230852)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Agitation
Ketamine Versus Midazolam for Prehospital Agitation
This research study is being done to figure out the best approach to treatment of pre-hospital agitation. It will compare two tiered dosing treatment protocols, one ketamine-based and one midazolam-based.
- Trial name
- NCT03554915
- Testing
- Ketamine-based protocol, Midazolam-based protocol
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- Hennepin Healthcare Research Institute
Epilepsy, Coma
Feasibility of Mini-EEG in the Prehospital Setting
The EEG is widely used in the diagnosis of central nervous system pathology, including epileptic seizures and epilepsy. Presently, EEG is available only during office hours in most hospitals, pending on the availability of a…
- Trial name
- NCT02329028
- Testing
- Prehospital mini-EEG
- Where
- Finland
- Volunteers
- 23 people
- Sponsor
- Helsinki University Central Hospital
Pain, Acute Pain
Prehospital Analgesia With Intra-Nasal Ketamine
Acute painful conditions make-up a large proportion of pre-hospital transports in British Columbia (BC) yet Basic Life Support (BLS) paramedics have limited options to provide analgesia and therefore adequate and timely pain…
- Trial name
- PAIN-K (NCT02753114)
- Testing
- Ketamine, Normal Saline
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Analgesia, Prehospital
Quality of Telemedically Guided Prehospital Analgesia
The purpose of this retrospective study is to analyze quality and adverse events of analgesia by telemedically supported paramedics in comparison to conventional treatment by on-scene emergency medical service (EMS) physicians in…
- Conditions
- Analgesia, Prehospital, Telemedicine, Ambulance
- Trial name
- NCT02928705
- Testing
- physician operated telemedical prehospital analgesia, prehospital analgesia by on-scene EMS physicians
- Where
- Germany
- Volunteers
- 381 people
- Sponsor
- RWTH Aachen University
Epilepsy, Status Epilepticus
Diagnostic Value of Prehospital EEG in Non-convulsive Status Epilepticus
A large proportion of patients (up to 20%) who suffer from an epileptic seizure and remain unconscious suffer from a non-convulsive epileptic seizure.
- Trial name
- NCT02344706
- Testing
- Registration of EEG
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Chest Pain
A Study of the Feasibility of Prehospital Remote Ischemic Conditioning
Prospective, single center, single arm pilot study evaluating the feasibility of delivering remote ischemic conditioning (RIC) by emergency medical services (EMS) in the prehospital setting.
- Trial name
- NCT03400579
- Testing
- autoRIC® device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Cardiac Arrest, Out-Of-Hospital, Hypotension and Shock
BCG Biosensor and Non- and Invasive Monitoring During Emergency Medicine Cases, a Prospective Feasibility Study
In a out of hospital emergency medicine study the investigators will measure hemodynamic effects of implemented treatments for patients with cardiac arrest, hypotension, and intensive care transports.
- Trial name
- NCT04891380
- Testing
- LUCAS 2 Active Decompression 2, Hypotension, Intensive care transport
- Where
- Norway
- Volunteers
- 183 people
- Sponsor
- Oslo University Hospital
Traumatic Brain Injury
Prehospital Severe Traumatic Brain Injury
The aim of the study is to measure the effect of Finnish physician-staffed EMS unit treatment methods on traumatic brain injury (TBI) patient prognosis.
- Trial name
- NCT02659046
- Where
- Finland
- Volunteers
- 266 people
- Sponsor
- Tampere University Hospital
Emergency Medical Services, Airway Management
The Evaluation of Training an Emergency Reflex Action Drill in the Emergency Surgical Airway in Dutch Paramedics
The goal of this observational study is to learn about the effects of training an Emergency Reflex Action Drill (ERAD) for Emergency Surgical Airway (ESA) in Dutch paramedics.
- Conditions
- Emergency Medical Services, Airway Management, Cricothyroidotomy, Prehospital
- Trial name
- ERAD-ESA (NCT06645288)
- Testing
- Emergency Reflex Action Drill
- Where
- Netherlands
- Volunteers
- 84 people
- Sponsor
- Erasmus Medical Center
Sepsis, Sepsis Syndrome
Predict Sepsis; the Predictive Value of Bedside Measures in the Ambulance
Sepsis is a condition with a high mortality. Septic patients are frequently difficult to identify because of their non-specific presentations.
- Conditions
- Sepsis, Sepsis Syndrome, Sepsis, Severe
- Trial name
- NCT03249597
- Testing
- Blood test: Glukos, SuPAR, Laktat and HBP
- Where
- Sweden
- Volunteers
- 956 people
- Sponsor
- Karolinska Institutet
Drowning, Drowning, Near
Developing an Utstein-style Danish Drowning Registry: Nationwide Fatal and Nonfatal Drowning Data Since 2016
This nationwide, registry-based study aims to link Danish Prehospital Drowning Data data with inhospital data to develop a Utstein-style Danish Drowning Registry.
- Conditions
- Drowning, Drowning, Near, Drowning; Asphyxia, Drowning and Nonfatal Submersion
- Trial name
- DROWN_INHOS (NCT06334276)
- Testing
- Drowning
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Prehospital Center, Region Zealand