Clinical trials: Prehospital Emergency
Wounds and Injuries, Acute Coagulopathy
Rapid Administration of Blood by HEMS in Trauma
Trauma is a leading cause of death among people younger than 44 years. Five million people worldwide die from trauma annually. Uncontrolled haemorrhage causing traumatic-haemorrhagic shock (THS) is the leading cause of…
- Conditions
- Wounds and Injuries, Acute Coagulopathy, Trauma
- Trial name
- RABBIT (NCT03522636)
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- Zdravotnicka Zachranna Sluzba Kralovehradeckeho Kraje
Acute Coronary Syndrome
Telemedical Support in Prehospital Emergency Care of Acute Coronary Syndrome
The aim of the study is to investigate the quality of prehospital emergency care in acute coronary syndromes, when paramedics are supported telemedically by an EMS physician.
- Trial name
- NCT01644006
- Testing
- Teleconsultation
- Where
- Germany
- Volunteers
- 39 people
- Sponsor
- RWTH Aachen University
Acute Pain
A Randomized, Double-blind Comparison of Morphine and Sufentanil for Prehospital Traumatic Severe Acute Pain
Obtaining high-quality analgesia in prehospital patients with severe pain is an important treatment objective for medical team. Opioids are recognized as the treatment of choice for relief of severe acute pain.
- Trial name
- NCT00656773
- Testing
- Sufentanil, Morphine
- Where
- France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Toulouse
Injury of Cervical Spine, Cervical Spine Fractures
Prospective Pilot Study Validating the Canadian C-Spine Rule Pre-hospital
This study is designed to evaluate the safety, level of performance and level of comfort with the Canadian C-Spine rule in a prehospital setting by emergency medicine undergraduates.
- Trial name
- NCT01278511
- Testing
- Canadian C-Spine rule
- Where
- Belgium
- Sponsor
- KU Leuven
Cardiac Arrest, Trauma
Pre-Hospital Advanced Airway Management in the Nordic Countries
Pre-Hospital Advanced Airway Management (PHAAM) is a potentially lifesaving intervention. A recent Danish multicentre single country study demonstrated a 99,7% incidence of successful anaesthesiologist pre-hospital endotracheal…
- Conditions
- Cardiac Arrest, Trauma, Traumatic Brain Injury, Hypoventilation
- Trial name
- PHAST (NCT02450071)
- Where
- Sweden
- Volunteers
- 2,028 people
- Sponsor
- Karolinska Institutet
Wounds and Injuries, Accidents, Occupational
Work Related Injuries Among Prehospital Emergency Medical Staff, an Observational Study
Ambulance personnel often work in a dangerous environment and work related injuries of emergency medical staff have repeatedly been documented.
- Trial name
- NCT01091610
- Testing
- no intervention
- Where
- 2 sites in Switzerland
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Resuscitation, Prehospital Emergency
CPR Quality in Via Ferrata Rescues
This study evaluates the effectiveness of CPR during via ferrata rescues, focusing on response quality and outcomes in challenging outdoor settings.
- Trial name
- NCT06070077
- Testing
- Chest compressions
- Where
- Czechia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Zdravotnicka Zachranna Sluzba Karlovarskeho Kraje, P.O.
Out-of-Hospital Cardiac Arrest
Reduction of Oxygen After Cardiac Arrest
The Reduction of oxygen after cardiac arrest (EXACT) is a multi-centre, randomised, controlled trial (RCT) to determine whether reducing oxygen administration to target an oxygen saturation of 90-94%, compared to 98-100%, as soon…
- Trial name
- EXACT (NCT03138005)
- Testing
- target SpO2 98-100%, target SpO2 90-94%
- Where
- 21 sites in Australia
- Volunteers
- 428 people
- Sponsor
- Monash University
Severe Traumatic Pain, Numeric Pain Rating Scale > 5 / 10
Intra Nasal Sufentanil Versus Intravenous Morphine for Acute Severe Traumatic Pain Analgesia in Emergency Setting
Intranasal (IN) administration of opiates is an appealing non-invasive way of treating acute traumatic pain in prehospital and Emergency departments (ED).
- Trial name
- ALGOFINE-2 (NCT02095366)
- Testing
- Morphine, Sufentanil
- Where
- 6 sites in France
- Volunteers
- 194 people
- Sponsor
- University Hospital, Grenoble
Blood Pressure
Comparison of Continuous Non-invasive Pressure Device Versus Invasive Pressure Measurement During Prehospital Emergency
The aim of the study is to evaluate the accuracy of continuous non-invasive AP monitoring (CNAP) compared to simultaneous IBP measurement in intensive care patients undergoing a transport in the ambulance car.
- Trial name
- NCT01627470
- Testing
- CNAP-Monitor
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Robert Hanss
Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Arrest
Relevance of Reversible Causes During OHCA (Rebecca Study)
Management of the reversible causes in cardiac arrest is fundamental for successful treatment of out-of-hospital cardiac arrests.
- Trial name
- REBECCA (NCT05784480)
- Testing
- Checklist for evaluation of reversible causes
- Where
- 2 sites in Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Tracheal Intubation Morbidity, Emergency Medicine
Tracheal Intubation and Prehospital Emergency Setting
In prehospital emergency setting, tracheal intubation is a frequent procedure (8% of interventions). Its objective is to control and protect upper airways and to optimize ventilation and oxygenation in patients with…
- Trial name
- SMURIDS (NCT03486171)
- Where
- 5 sites in France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Bordeaux
Endotracheal Intubation, Deep Sedation
Inhaled Sedation Using the Anesthetic-conserving Device ( ANACONDA) in Prehospital Emergency Medecine.
Achieving the optimal sedation level for patient management is not always possible using our standard intravenous medications in Pre-hospital Emergency medicine.
- Trial name
- ANACONDA (NCT04141267)
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Hemorrhage, Hypovolemic Shock
Efficacy of Prehospital Tourniquet Models for Arterial Occlusion in Upper and Lower Limbs
The goal of this clinical trial is to compare the occlusive capability and mechanical behavior of different commercially available pre-hospital tourniquet models and the results of their application on upper and lower limbs, in…
- Conditions
- Hemorrhage, Hypovolemic Shock, Tourniquets
- Trial name
- TQ-BR (NCT06725602)
- Testing
- TQ - Proximal Application ("high and tight"), TQ - Controlled application (2-3 inches)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Telemedicine, Intubation; Difficult or Failed
Teleguidance-facilitated Airway Management
The advent of telemedicine has introduced teleguidance as a promising support to enhance endotracheal intubation skills among inexperienced operators.
- Conditions
- Telemedicine, Intubation; Difficult or Failed, Emergencies
- Trial name
- NCT06497725
- Testing
- Teleguidance-facilitated Airway Management
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Carbon Monoxide Poisoning
Role of Pulse Co-oximetry for Detecting Carbon Monoxide Poisoning in the Prehospital Emergency Medical Service Setting
The RAD-57 pulse CO-oximeter is a lightweight device allowing non-invasive measurement of blood carboxyhemoglobin. Previous studies comparing RAD-57 measurements (SpCO) to standard laboratory blood gas analysis (COHb) have…
- Trial name
- CO-OX (NCT02860455)
- Testing
- RAD57 measurement (SpCO), CO-oximeter
- Where
- France
- Volunteers
- 176 people
- Sponsor
- University Hospital, Montpellier
Infarction
Myocardial Infarction Safe Emergency Medicine Accompanying Study: Providing Reperfusion Therapy Within the Recommended Time Limits
The project is a prospective observational study with the aim of system improvement. It represents accompanying research in connection with the implementation of Safe Emergency Medicine , - an initiative under the auspices of the…
- Trial name
- NCT07092904
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- University Hospital of North Norway
Myocardial Infarction
Acute Versus Subacute Angioplasty in Patients With NON-ST-Elevation Myocardial Infarction
Patients with acute myocardial infarction (AMI) are categorized according to the electrocardiogram (ECG) findings into: 1) patients with ST-Elevation Myocardial Infarction (STEMI), 2) patients with Bundle Branch Block Myocardial…
- Trial name
- NONSTEMI (NCT01638806)
- Testing
- Group I: Primary PCI
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Aarhus University Hospital Skejby
Sudden Cardiac Arrest, Out-of-hospital Cardiac Arrest (OHCA)
FEMART-1 Pilot Study
The FEMART-1 Pilot Study is focused on evaluating the feasibility, safety, and procedural timing of prehospital femoral arterial sheath placement in patients with non-traumatic out-of-hospital cardiac arrest (OHCA), both during…
- Conditions
- Sudden Cardiac Arrest, Out-of-hospital Cardiac Arrest (OHCA), Cardiogenic Shock Acute
- Trial name
- FEMART-1 (NCT07596446)
- Testing
- Prehospital Ultrasound-Guided Femoral Arterial Sheath Placement
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Emergency Medical Service, Prague
Mass Casualty Incidents
Impact of Ten Second Triage vs. Sieve on Triage Performance in Simulated Mass-Casualty Incidents
This study will compare two emergency triage algorithm - Ten Second Triage (TST) versus Sieve - to see which one works better during simulated mass-casualty incidents.
- Trial name
- NCT07436052
- Testing
- Ten Second Triage algorithm, Sieve triage algorithm
- Where
- Switzerland
- Volunteers
- 201 people
- Sponsor
- Stuby Loric