Clinical trials: Preoperative
Rotator Cuff Tears
The Effect of a Pre-operative Exercise Program for Patients With Full Thickness Rotator Cuff Tear Waiting for Surgical Repair
This is a randomised controlled study involving a group of 20 patients- 10 patients in a control group, 10 patients in treatment group.
- Trial name
- NCT02208752
- Testing
- Exercises
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Dental Anxiety
Evaluation on the Anxiety of Third Molar Extraction
This study was performed on 66 patients who were admitted for third molar extraction under local anesthesia. The patients were divided into three groups: group 1 with verbal information, group 2 with written information, and…
- Trial name
- NCT03838081
- Testing
- Spielberger State Anxiety Inventory (STAI-S),, Dental Fear Scale (DFS), Modified Dental Anxiety Scale (MDAS)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ankara University
Post-operative Pain
Comparison of Preoperative Ultrasound Guided Pectoralis Nerve Block Placement Versus Intra-operative Placement: A Prospective Randomized Trial
This study investigates the use of post-operative on-Q pain catheters for tissue expander based breast reconstruction, versus conventional ultrasound-guided blocks placed pre-operatively.
- Trial name
- NCT03201809
- Testing
- On-Q, Ultrasound guided pectoral nerve block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Anxiety, Separation
A Comparison of Two Doses of Intranasal Dexmedetomidine for Premedication in Children
The purpose of the study is to determine if 4mcg/kg of intranasal dexmedetomidine is better than 2mcg/kg in successfully sedating a child prior to induction of anesthesia.
- Trial name
- NCT02459509
- Testing
- Dexmedetomidine
- Where
- Hong Kong
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Vaginal Surgeries
Efficacy of Two Vaginal Solutions in Preoperative Use
This study is necessary in order to provide proof the effectiveness of Chlorhexidine gluconate and its safety.
- Trial name
- NCT03014778
- Testing
- The Chlorhexidine gluconate 0.05%, 10% Povidone iodine
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Skin Cancer, Skin Wound
Preoperative Image-based Education Effect on Postoperative Satisfaction of Patients Undergoing First-time Dermatologic Surgery
This research study aims to understand whether visual and written education on wound appearance can improve patients' experience and understanding of what their wound will look like following dermatologic surgery.
- Trial name
- NCT05643755
- Testing
- Preoperative image-based education
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Gynecologic Laparoscopic Surgery, Minimally Invasive Surgical Procedures
Impact of a Preoperative Instructional Video on Patient Preparedness
In this study, the investigators will evaluate the impact of a pre-operative instructional video for patients undergoing minimally invasive gynecologic surgery.
- Trial name
- NCT07364968
- Testing
- Study group of patients will receive standard of care
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of California, Riverside
Arthritis of the Hip, Transfusion Related Complications
Preoperative Versus Postoperative Start With Thromboprophylaxis in THA (Total Hip Arthroplasty)
The purpose of this study is to determine if there are differences in clinical events, i.e bleeding with associated morbidity, if thromboprophylaxis with LMWH (Low Molecular Weight Heparin) is initiated before or after surgery.
- Conditions
- Arthritis of the Hip, Transfusion Related Complications, Infection, Wound Discharge
- Trial name
- NCT01714297
- Testing
- dalteparin 5000 IU s.c.
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vestre Viken Hospital Trust
Colorectal Surgery
Efficacy Comparison of Two Preoperative Skin Antisepsis Preparations in Colorectal Surgery
Surgical site infections (SSI) are one of the most common complications in the post-operative patient, and the second most common health care associated infection overall.
- Trial name
- NCT01233050
- Testing
- 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol, Iodine Povacrylex/74% Isopropyl Alcohol
- Where
- 3 sites in United States
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Fasting, Delayed Gastric Emptying
Gastric Assessment of Pediatric Patients Undergoing Surgery
The goal of this pilot prospective cohort study is to examine the reproducibility of gastric volume and emptying as measured by gastric ultrasound and its correlation to a gold-standard test for gastric emptying in the…
- Conditions
- Fasting, Delayed Gastric Emptying, Aspiration Pneumonia, Respiratory Aspiration of Gastric Content
- Trial name
- NCT05674643
- Testing
- Gastric Ultrasound Baseline Scans, Acetaminophen Absorption Test (AAT), Gastric Ultrasound Serial Scans
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Anxiety, Opioid Consumption
Associations Between Analgesia Nociception Index and Preoperative Anxiety
The management and prediction of pain is one of the most crucial jobs for anesthetists. It has been shown that a patient's ability to remain calm during stressful situations is related to their post-surgical pain scores.
- Conditions
- Anxiety, Opioid Consumption, Cesarean Section
- Trial name
- PANIC (NCT04875572)
- Testing
- Analgesia Nociception Index (ANI) Monitor
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hypotension, Nausea
Hemodynamic Protection of Preoperative Ondansetron 15 Minutes Before Spinal Anaesthesia in Caesarean Section
Spinal anaesthesia for caesarean section is the most commonly used anaesthetic choice in caesarean deliveries. This is usually associated with maternal hypotension and other adverse side effects.
- Conditions
- Hypotension, Nausea, Vomiting
- Trial name
- NCT04140058
- Testing
- Ondansetron, Normal saline
- Where
- Jordan
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Delirium, Cognitive Impairment
Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement)
There is lack of attention to preoperative cognitive function and delirium in elderly who underwent surgery. The investigators are investigating different tools that can help to screen for cognitive dysfunction and delirium in…
- Conditions
- Delirium, Cognitive Impairment, Cognitive Dysfunction, Cognitive Dysfunction, Postoperative
- Trial name
- NCT05209555
- Testing
- MoCA, BAMCOG, DeltaScan
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Living Kidney Donation, Preoperative Anxiety
Preoperative Psychotherapy and Its Effects on Anxiety, Hemodynamics, and Pain in Living Kidney Donors
Chronic kidney failure is a condition in which the kidneys progressively lose their ability to filter waste, maintain fluid and electrolyte balance, and support essential physiological functions.
- Conditions
- Living Kidney Donation, Preoperative Anxiety, Postoperative Pain
- Trial name
- PREPSY-KD (NCT07261917)
- Testing
- Preoperative Psychiatric Consultation, No Intervention: Standard Preoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Cognitive Impairment
Preoperative Cognitive Screening in Older Surgical Patients Utility for Predicting Morbidity
The purpose of this work is to determine whether preoperative cognitive screening of patients over the age of 65 can be used as predictor of postoperative outcomes in patients undergoing lower extremity surgical procedures.
- Trial name
- NCT02598050
- Testing
- No Interventions as this is a observational study
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Ureteral Injury
Intravenous Sodium Fluorescein Versus Oral Phenazopyridine for Ureteral Patency
To determine the safety profile of sodium fluorescein in women undergoing cystoscopy during gynecologic surgery. To determine if either oral phenazopyridine or sodium fluorescein result in shorter cystoscopy times.
- Trial name
- NCT02757417
- Testing
- sodium fluorescein, phenazopyridine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pain, Postoperative, Postoperative Pain, Acute
Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries
This is a double-arm randomized control trial evaluating the impact of preoperative opioid-free analgesia on time to trial of void in ambulatory urogynecologic surgeries.
- Trial name
- NCT06379425
- Testing
- Acetaminophen, Celecoxib, Gabapentin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Coughing Responses at Tracheal Extubation, Breathing Patterns
Endotracheal Tube Intolerance and Respiratory Airflow Perception
This is a case-control study designed to enroll 224 patients who will undergo tracheal intubation for general anesthesia in the operating rooms of Peking University People's Hospital between July 20, 2026, and October 31, 2026.
- Trial name
- NCT07759284
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Anxiety, Pain, Postoperative
Postoperative Effects of Preoperative Anxiety
INTRODUCTION Patients who will have obesity surgery have about %48 psychiatric illnesses like anxiety disorder. Studies which analyze the relationship between preoperative anxiety level and postoperative pain had reported…
- Trial name
- NCT04432558
- Testing
- Spielberger's State-Trait Anxiety Inventory, Visual analog scale, Ramsay's sedation scale, Tramadol, paracetamol, diclofenac sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Baskent University
Day Surgery
What Matters to You When You Prepare for Surgery and How Does Surgical Preparedness Influence Postoperative Outcome
On the occasion of the international What Matters To You-day 2025 the goal of this Danish, multicenter flashmob study with follow up is to investigate what matters to adult patients when they prepare for surgery or colonoscopy.
- Trial name
- NCT07234643
- Where
- 3 sites in Denmark
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Gødstrup Hospital