Clinical trials: Preoperative Period
Anti-Psychotic, Management of Manifestations of Psychotic Disorders
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
Cycle Pharmaceuticals Ltd. (Cycle) is developing an oral tablet formulation of Chlorpromazine Hydrochloride and intends to conduct bioequivalence trials to demonstrate its similarity to the RLD.
- Conditions
- Anti-Psychotic, Management of Manifestations of Psychotic Disorders, Treatment of Schizophrenia, Control Nausea and Vomiting
- Trial name
- NCT02943213
- Testing
- Chlorpromazine Hydrochloride
- Where
- South Africa
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cycle Pharmaceuticals Ltd.
Acute Kidney Injury
Acute Kidney Injury Biomarkers: Diagnosis and Application in Pre-operative Period of Liver Transplantation
Acute kidney injury (AKI), is a common complication of patients undergoing liver transplantation. Timing and definition of AKI, usually based on serum creatinine, have been inaccurate and inconsistent.
- Trial name
- AKIB (NCT02095431)
- Where
- Brazil
- Volunteers
- 122 people
- Sponsor
- University of Sao Paulo
Obesity, Bariatric Surgery Candidate
Halitosis, Sleep and Mental Health in Bariatric Surgery Candidates
This study aims to evaluate psychological distress, sleep quality, and halitosis in obese patients during the preoperative period of bariatric surgery.
- Conditions
- Obesity, Bariatric Surgery Candidate, Halitosis, Sleep Disorder
- Trial name
- NCT07175142
- Volunteers
- 110 people
- Sponsor
- University of Nove de Julho
Total Knee Arthroplasty, Intraoperative Hypothermia
The Effect of Preoperative Active Warming on Intraoperative Body Temperature
A randomized controlled study was conducted to examine the effect of active warming before total knee arthroplasty on intraoperative body temperature and comfort.
- Trial name
- NCT05334589
- Testing
- Prewarming
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Colorectal Cancer
Evaluation of Quality of Life and Period of Hospitalization by Education
Patients with colorectal cancer prior to stoma surgery are randomized to different preoperative education programs: (a) specific preoperative education, (b) standard preoperative education.
- Trial name
- STELLA (NCT02526264)
- Testing
- Education program
- Where
- 2 sites in Germany
- Volunteers
- 138 people
- Sponsor
- Krankenhaus Nordwest
Frailty
A Pilot Study of High Intensity Walking in Older Adults in the Pre-operative Period
The purpose of this pilot study is to evaluate a high intensity walking intervention in older surgical candidates with kidney or thoracic disease and pre-frailty or frailty.
- Trial name
- NCT04241419
- Testing
- High Intensity Walking
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Chicago
Fasting Period, Intravascular Volume
The Impact of Preoperative Fasting Period on Cardiac Index Variability After Anesthesia Induction in Pediatric Patients
The minimum period of fasting recommended by the 'American Society of Anesthesiologists' for the preoperative period is 6 hours for solid foods and 2 hours for clear liquids.
- Trial name
- NCT03406481
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Marmara University
Pain Score, Pain Postoperative
Pain Sensitivity Questionnaire Applied in Preoperative Period in Lumpectomy
Objective: The Pain Sensitivity Questionnaire (PSQ) is a clinically valuable tool that has been shown to correlate with various experimental pain sensitivity assessments in healthy individuals and patients with chronic pain.
- Trial name
- Lumpectomy (NCT06928064)
- Testing
- Prediction of Postoperative Pain Severity Using Pain Sensitivity Questionnaire Applied in Preoperative Period in Patients Undergoing Breast-Conserving Surgery (Lumpectomy).
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Insulin Resistance, ERAS
Kelulut Honey as an Alternate Source of Carbo-Loading in Abdominal Surgery Involving the Digestive System
The study aims to identify if Kelulut Honey can be a potential alternative for the use of preoperative carboloading instead of the commercially available product, Carborie.
- Trial name
- Kel-Load (NCT04438590)
- Testing
- Kelulut Honey, Carborie
- Where
- Malaysia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Surgical Procedures, Anesthesia
Pre-anesthetic Evaluation and Cost Reduction
Study conducted in large Brazilian hospital, with the main objective of evaluating the impact of pre-anesthetic in reducing costs related to the preoperative preparation of patients admitted to undergo surgery or diagnostic…
- Trial name
- NCT01130610
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Santa Casa de Misericórdia de Belo Horizonte
Obesity, Morbid, Bariatric Surgery Candidate
The Effect of Progressive Relaxation Exercises on Bariatric Surgery Period
The goal of this clinical trial is to test the effect of the progressive relaxation exercises in perioperative bariatric surgery patient care.
- Conditions
- Obesity, Morbid, Bariatric Surgery Candidate, Anxiety, Postoperative Pain
- Trial name
- PREbari (NCT05591898)
- Testing
- Progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Anemia
A Study to Evaluate the Effectiveness and Safety of Epoetin Alfa During the Period When One is Donating One's Own Blood Before Surgery.
The purpose of this study is to evaluate the whether epoetin alfa stimulates the bone marrow to produce red blood cells and therefore increases a patient's ability to self-donate blood prior to major surgery.
- Trial name
- NCT00270179
- Testing
- epoetin alfa
- Volunteers
- 17 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Obstructive Sleep Apnea Risk Management, Postoperative Complications
OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia
Obstructive sleep apnea (OSA) is a sleep-related respiratory dysfunction. The prevalence of OSA is increasing with the increasing rates of obesity and elderly population worldwide.
- Conditions
- Obstructive Sleep Apnea Risk Management, Postoperative Complications, Dental Caries Under General Anesthesia, Obstructive Sleep Apnea of Adult
- Trial name
- NCT06430957
- Testing
- The STOP-BANG questionnaire for determining OSA risk level., ASA recommended criteria for determining OSA risk level., Record of postoperative complications
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Kırıkkale University
Pancreatic Ductal Adenocarcinoma
Hedgehog Inhibition for Pancreatic Ductal Adenocarcinoma (PDAC) in the Preoperative Setting (HIPPoS)
This clinical trial is looking at the effect of a new drug called GDC-0449 in patients with cancer of the pancreas. Laboratory studies have shown that this drug blocks a process in pancreatic cells thought to be involved in…
- Trial name
- HIPPoS (NCT01096732)
- Testing
- GDC-0449
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- Lisa Bax
Preoperative Anxiety
Augmented Reality Applied Book Reading in the Preoperative Period
Non-pharmacological methods such as multimedia applications and visual and auditory technological tools are used to create a more enjoyable experience by reducing children's fear and anxiety and distracting them in the…
- Trial name
- NCT06399016
- Testing
- augmented reality book, book
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Education, Nursing
Example of Escape Room in Nursing Student Education
Game-based learning is gaining increasing attention to meet the evolving needs of today's nursing students and the demand for 21st century skills in modern healthcare.
- Trial name
- NCT05830526
- Testing
- Escape Room
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Malnutrition; Protein, Frail Elderly Syndrome
Influence of Preoperative Nutritional Status on Perioperative Period in Cardiac Surgery in Patients With Frailty
The aim of the study is to determine whether the optimisation of the preoperative nutritional status affects the course of the perioperative period in patients with frailty.
- Trial name
- NCT05118165
- Testing
- Dietary supplement with protein
- Volunteers
- 176 people
- Sponsor
- Lithuanian University of Health Sciences
Neurocognitive Disorders, Postoperative Period
Pre-operative Neurocognitive Disorder and Low Near-infrared Spectrometry is Associated With Postoperative Delirium
The main goal of the investigation is to identify the incidence of cognitive dysfunction and POD in patients older than 65 years of age undergoing neurosurgical elective surgery and determine if an association between cognitive…
- Conditions
- Neurocognitive Disorders, Postoperative Period, Postoperative Complications
- Trial name
- NCT03171766
- Testing
- Mini-Mental State Examination (MMSE), Visual Analog Scale (VAS), Mini Cog test
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Centro Hospitalar do Porto
Preoperative, Sleep
The Effect of the Use of Gel Pillows on the Sleep Quality and General Comfort Levels
The study was conducted to evaluate the effect of using gel pillows on the sleep quality and general comfort levels of patients in the preoperative period.The main hypotheses are: H1: 'The sleep quality of patients who use gel…
- Conditions
- Preoperative, Sleep, Comfort
- Trial name
- NCT06025136
- Testing
- Using a gel pillow
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trakya University
Pancreatic Diseases
The Effect of Preoperative Long Period Octreotide Combined With Postoperative Short Period Octreotide on the Complications After Pancreatectomy. A Prospective, Multicenter Clinical Trial
The Effect of Preoperative Long Period Octreotide Combined With Postoperative Short Period Octreotide on the Complications After Pancreatectomy. A Prospective, Multicenter Clinical Trial
- Trial name
- NCT03398941
- Testing
- Preoperative Long Period Octreotide Combined With Postoperative Short Period Octreotide
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chengfeng Wang