Clinical trials: Preventive Intervention
PrEP, PrEP Adherence Monitoring
Prevention ICONA Dedicated Ensemble
Despite significant advances in HIV treatment, transmission remains a public health concern. In 2022, there were 1.3 million new HIV infections worldwide and 1,888 new diagnoses in Italy, with sexual transmission being the…
- Conditions
- PrEP, PrEP Adherence Monitoring, HIV, HIV -1 Infection
- Trial name
- PrIDE (NCT07186244)
- Where
- 53 sites in Italy
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Fondazione ICONA
Cardiovascular Diseases, Diabetes
The Flamenco (Fitness League Against MENopause COsts) Project
Spain is the second country in the world that consume more drugs. The average drug expenditure per capita in Andalucía during 2011 was 219.2 €. This drug spending increases during the perimenopausal period.
- Conditions
- Cardiovascular Diseases, Diabetes, Dyslipidemias, Metabolic Syndrome
- Trial name
- FLAMENCO (NCT02358109)
- Testing
- exercise
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Sexual Behavior, Pregnancy Early
Evaluation of the Teen Outreach Program in Hennepin County, Minnesota
This study tested the extent to which TOP®, when replicated with fidelity, produced impacts on sexual risk-taking behaviors in the short term and the longer term.
- Trial name
- NCT02510209
- Testing
- Teen Outreach Program
- Where
- United States
- Volunteers
- 1,644 people, healthy volunteers welcome
- Sponsor
- Abt Associates
Cervical Cancer
Promoting Comprehensive Cervical Cancer Prevention and Better Women Health in Cameroon
In sub-Saharan Africa, cervical cancer is the leading cause of cancer death among women because of the difficulty in implementing screening programs.
- Trial name
- PCCCP (NCT03757299)
- Testing
- HPV Test
- Where
- Switzerland
- Volunteers
- 4,473 people, healthy volunteers welcome
- Sponsor
- Prof. Patrick Petignat
Cancer
Prioritising Prevention of COVID-19 in Persons With Cancer in the French West Indies
The public health council (Haut Conseil de Santé Publique) published a statement on 14 March 2020 relating to the management of patients with severe forms of COVID-19, stipulating specific recommendations for patients with…
- Trial name
- RESILIENCE (NCT04768153)
- Testing
- Serology
- Where
- Martinique
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Obesity, Prevention & Control
KAN-DO: A Family-based Intervention to Prevent Childhood Obesity
The purpose of this study is to evaluate the efficacy of an intervention (KAN-DO: Kids \& Adults Now - Defeat Obesity) encouraging postpartum mothers and their preschool-aged children to work together to promote healthy eating…
- Conditions
- Obesity, Prevention & Control, Postpartum Period
- Trial name
- KAN-DO (NCT00563264)
- Testing
- KAN-DO
- Where
- 2 sites in United States
- Volunteers
- 832 people, healthy volunteers welcome
- Sponsor
- Duke University
Anaemia, Malaria
Intermittent Preventive Treatment for Malaria in Infants in Navrongo Ghana
Evaluation of the safety and effectiveness of malaria intermittent chemotherapy and iron supplementation delivered through Expanded Programme on Immunisation vaccination clinics.
- Trial name
- NCT00857077
- Testing
- Sulfadoxine-pyrimethamine
- Where
- Ghana
- Volunteers
- 2,485 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Early Childhood Caries, Dental Caries
Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project
The purpose of this study is to determine whether a bundled best practices oral health intervention utilizing motivational interviewing versus a didactic maternal and child healthy lifestyle intervention will reduce childrens'…
- Trial name
- NCT04556175
- Testing
- Oral Health, Healthy Lifestyle
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Assault by Handgun Discharge, Violence
Lithium Water in Gun Violence Prevention
The word lithium frequently conjures images of catatonic psychiatric patients and side effects so severe that premature death is commonplace. But naturally occurring lithium is a far cry from pharmaceutical grades.
- Conditions
- Assault by Handgun Discharge, Violence, Homicide, Sexual Assault by Bodily Force
- Trial name
- LWGVP (NCT02213614)
- Testing
- Lithium Water, natural spring water
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- American Society Of Thermalism And Climatology Inc
Depression, Anxiety Disorders
Rumination-focused CBT Training for the Prevention of Depression and Anxiety
Depression and anxiety disorders are highly prevalent and associated with reduced quality of life for patients and enormous economic costs for society.
- Trial name
- NCT01223677
- Testing
- Rumination Focused CBT
- Where
- Netherlands
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Malaria
Prevention of Malaria With Dihydroartemisinine + Piperaquine for Forest Rangers
The purpose of the study is to assess if the antimalarial drugs Dihydroartemisinine + Piperaquine (DP) are effective in preventing malaria infection for forest ranger
- Trial name
- PREMAL (NCT02788864)
- Testing
- Arterakine (DHA/piperaquine)
- Where
- Vietnam
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
HIV Prevention, Contraception Behavior
Couple User Preferences in Dual Purpose Prevention Products
MTN-045 is a cross-sectional study that will utilize questionnaires, including Discrete-Choice Experiments (DCE) and joint decision tasks, to assess couples' preferences related to dual purpose prevention (DPP) products that…
- Trial name
- CUPID (NCT04023799)
- Where
- 2 sites in Uganda, Zimbabwe
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Microbicide Trials Network
E-Cig Use, Vaping
A Virtual Reality Videogame for E-cigarette Prevention in Teens
The use of the Invite Only VR, with the aim to prevent the initiation of e-cigarette use in teens by increasing their knowledge, decreasing their intentions to use e-cigarettes, influencing their harm perceptions and attitudes…
- Trial name
- NCT04054765
- Testing
- videogame, treatment as usual
- Where
- United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Yale University
Staphylococcus Aureus, MRSA Skin Infections
Methicillin-resistant Staphylococcus Aureus (MRSA) Skin and Soft Tissue Infection (SSTI) Prevention in Military Trainees
This cluster-randomized prospective study will evaluate the effect of hygiene-based intervention strategies on the incidence of overall SSTI and MRSA-associated SSTI among military trainees.
- Conditions
- Staphylococcus Aureus, MRSA Skin Infections, Staphylococcal Skin Infections
- Trial name
- NCT01105767
- Testing
- Chlorhexidine gluconate, Supplemental training, education and hygiene
- Where
- United States
- Volunteers
- 30,209 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Wheelchair Users, Pressure Ulcer Prevention
The Effect of Pressure Injury Training on Knowledge Levels and Wound Prevention in Wheelchair Users
This research is a randomised controlled study conducted to evaluate the effects of training given to wheelchair users to prevent pressure injury on their level of knowledge, prevention of pressure injury and wound healing.
- Conditions
- Wheelchair Users, Pressure Ulcer Prevention, Pressure Ulcer (PU)
- Trial name
- NCT07438899
- Testing
- education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Pressure Injury, Nursing Competency
NURSING COMPETENCY SCALE IN PRESSURE INJURY PREVENTION: A SCALE DEVELOPMENT STUDY
Pressure injuries remain an important patient safety problem and are associated with prolonged hospitalization, increased healthcare costs, pain, and reduced quality of care.
- Trial name
- NCSPIP (NCT07590765)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Prevention of COVID-19
ZF2001 Booster Immunization Clinical Trials of 6 Months After the Completion of Basic Immunization
The purpose of this study is to evaluate the immunogenicity and safety of the recombinant novel coronavirus vaccine (CHO cells) after the booster immunization.
- Trial name
- NCT05198063
- Testing
- Recombinant novel coronavirus vaccine (CHO cells)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Pre-Exposure Prophylaxis
Identification of the Pre-exposure Prophylaxis (PrEP) Cascade for Women.
Pre-exposure prophylaxis (PrEP) is a daily pill that greatly reduces the risk of transmission of human immunodeficiency virus (HIV), however the barriers to PrEP use for women are understudied and PrEP is underutilized by women.
- Trial name
- PrEP (NCT03705663)
- Testing
- PrEP initiation
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Teenage Pregnancy
LeadHer, a Gender-specific Teen Pregnancy Prevention Curriculum for Girls 15-19
Alternatives For Girls (AFG) is offering LeadHer as a gender-specific teen pregnancy prevention curriculum to girls between the ages of 14-19 years old who live in Wayne County, MI.
- Trial name
- NCT03265314
- Testing
- LeadHer, Sassy Science
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Alternatives For Girls
Health Promotion, Older Adults (65 Years and Older)
SCT-Based Health Promotion in Older Adults
This study will be conducted to compare the effects of Peer- and Nurse-Led Health Protection and Promotion Training Programs Based on Social Cognitive Theory (SCT) on the health behaviors of older adults.
- Trial name
- NCT06419465
- Testing
- Peer-Led Health Protection and Promotion Training Program, Health Protection and Promotion Training Program under the Leadership of a Public Health Nurse
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
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