Clinical trials: Preventive Intervention
Low Education, Cognition
MINDSpeed Food and Brain Training RCT
The purpose of this study is to learn how foods high in polyphenols and brain training exercises affect older adults' cognitive performance
- Conditions
- Low Education, Cognition, Cognitive Training, Polyphenols
- Trial name
- MINDSpeed (NCT03419052)
- Testing
- Speed of processing training, MIND foods, Cognitive training control
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Indiana University
Self-Efficacy, Food Choices
Nutrition Labelling Education Program in Socioeconomically Vulnerable Areas - PILOT STUDY
Front-of-pack nutrition labels (FoPLs) have been adopted in many countries to help consumers rapidly assess the nutritional quality of foods and to encourage healthier choices.
- Conditions
- Self-Efficacy, Food Choices, Understanding of Front-of-pack Labeling
- Trial name
- PEANUTS-PILOT (NCT07531849)
- Testing
- Peanuts
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Paris 13
Dental Caries
Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant
This study will evaluate effectiveness of a urethane dimethacrylate (UDMA)-quaternary ammonium methacrylate (K18) resin (UDMA-K18) smooth surface sealant to prevent biofilm attachment to tooth surfaces thereby eliminating the…
- Trial name
- K18 (NCT03306433)
- Testing
- UDMA-K18 smooth surface sealant
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Language Disorders in Children, Learning; Developmental Disorder
Impact of Teacher Training and the Introduction of Early Adjustments on the Developmental Trajectory of Children at Risk of SLLD in Pre-school.
The high incidence of neurodevelopmental disorders, including specific language and learning disorders, and their profund impact on the schooling of the children concerned remains a major public health concern.
- Trial name
- PRISME-TSLA (NCT06062147)
- Testing
- Teacher training
- Where
- Reunion
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
HIV Infections
Pivotal Phase 2b/3 ALVAC/Bivalent gp120/MF59 HIV Vaccine Prevention Safety and Efficacy Study in South Africa
This study will evaluate the preventive vaccine efficacy, safety, and tolerability of ALVAC-HIV (vCP2438) + Bivalent Subtype C gp120/MF59 in HIV-seronegative South African adults over 24 months and potentially up to 36 months…
- Trial name
- HVTN702 (NCT02968849)
- Testing
- ALVAC-HIV (vCP2438), Bivalent Subtype C gp120/MF59
- Where
- 14 sites in South Africa
- Volunteers
- 5,404 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Diphtheria, Acellular Pertussis
Immunogenicity & Safety of GSK's Combined DTPa-HBV-IPV/Hib Vaccine in Indian Infants at 2 Diff Vaccination Schedules
In this study, infants who were previously vaccinated with hepatitis B vaccine at birth will be randomly allocated into two groups: one group of subjects will receive diphtheria, tetanus, acellular pertussis- hepatitis B…
- Conditions
- Diphtheria, Acellular Pertussis, Tetanus, Haemophilus Influenzae Type b
- Trial name
- NCT00316147
- Testing
- DTPa-HBV-IPV/Hib vaccine
- Where
- 4 sites in India
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Peri-implant Mucositis
Impact of Glycine Therapy on Peri-implant Mucositis
The purpose of this research study is to determine the impact of glycine powder air-abrasive debridement (GPAD) on the microbiology of the tissues surrounding dental implants with health and inflammation (peri-implant mucositis).
- Trial name
- NCT05810558
- Testing
- glycine powder air-powered debridement, Ultrasonic instrumentation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Opioid Use Disorder, Substance Use Disorders
Minds and Mentors Program- R33
The proposed research effort will: The purpose of this study is as follows: 1. Test the effectiveness of the Minds and Mentors Program in a group treatment trial in which individuals using medications for opioid use disorder…
- Conditions
- Opioid Use Disorder, Substance Use Disorders, Medication Assisted Treatment
- Trial name
- MiMP (NCT05363371)
- Testing
- Minds and Mentors, Twelve Step Intervention Group
- Where
- 4 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
HIV Prevention, HIV Infections
Rectal Microbicide Safety and Acceptability Trial of Topically Applied Tenofovir Compared With Oral Tablet
To date, the majority of microbicide research has focused on the assessment of the safety and effectiveness of vaginal microbicides used for the prevention of HIV transmission via the vaginal compartment.
- Trial name
- RMP02-MTN006 (NCT00984971)
- Testing
- Tenofovir, Open label tenofovir tablet
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- CONRAD
Accidental Falls, Balance Assessment
Otago Exercise Programme and Physical Function in Older Adults in Sarawak
This randomized controlled trial aims to evaluate the effects of the Otago Exercise Programme (OEP) on physical fitness, balance, and quality of life among older adults in Sarawak, Malaysia.
- Conditions
- Accidental Falls, Balance Assessment, Physical Fitness
- Trial name
- OEP (NCT07258550)
- Testing
- Otago Exercise Programme (OEP)
- Where
- Malaysia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Malaysia Sarawak
Alzheimer's Disease, Aging
aeRobic Exercise and Cognitive Health
The purpose of the aeRobic Exercise and Cognitive Health (REACH) study is to understand how an aerobic exercise intervention might help promote brain health and cognition, thereby delaying the onset of clinical symptoms of…
- Trial name
- REACH (NCT02384993)
- Testing
- Enhanced Physical Activity
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Dental Caries, Fissure Sealant
The Effect of an Adhesive System on the Retention and Caries Prevention for Fissure Sealants in Permanent Molars
Background: Resin-based fissure sealants (FS) are recommended to prevent pit-and-fissure caries development or prevent the progression of enamel caries lesion to frank cavitation into dentine.
- Trial name
- ResinFS (NCT06608563)
- Testing
- Fissure sealant without adhesive system (NO BOND), Fissure sealant with adhesive system (BOND)
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
HIV, Physical Abuse of Adult (If Focus of Attention is on Victim)
Assessing the Impact of an Intervention to Prevent Intimate Partner Violence and HIV in Uganda
Intimate partner violence (IPV) is a precursor to and consequence of HIV infection. Few interventions combining HIV and IPV prevention have been evaluated and none has significantly decreased both outcomes.
- Conditions
- HIV, Physical Abuse of Adult (If Focus of Attention is on Victim), Sexual Abuse of Adult (If Focus of Attention is on Victim), Risk Reduction Behavior
- Trial name
- SHARE (NCT02050763)
- Testing
- The SHARE Project
- Where
- Uganda
- Volunteers
- 11,451 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV
Implementation Effectiveness and Safety of Tenofovir Gel Provision Through Family Planning Services
The purpose of this study is to assess the effectiveness of an implementation model which integrates tenofovir gel provision into existing family planning services.
- Trial name
- NCT01691768
- Testing
- 1% tenofovir gel
- Where
- 2 sites in South Africa
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
Obesity
New Moves - Obesity Prevention Among Adolescent Girls
The New Moves study will evaluate the impact of a school based program for inactive high school girls who are overweight or at risk for being overweight due to low levels of physical activity.
- Trial name
- NCT00250497
- Testing
- New Moves
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Prevention
The Safe Teen Study
The study examines (1)the incidence of preventive health services provided by family physicians to adolescent patients, and (2)barriers and facilitators of prevention discussions between family physicians and their adolescent…
- Trial name
- NCT00380510
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Driving While Intoxicated
WayToServePlus: Improving Responsible Alcohol Service Ph I
Responsible beverage service (RBS) training for alcohol servers is a promising intervention for reducing driving while intoxicated (DWI) by alcohol.
- Trial name
- NCT05146024
- Testing
- Way To Serve Plus: Improving Responsible Alcohol Service
- Where
- 2 sites in United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Teen Pregnancy, Sexually Transmitted Infections
An Evaluation of Pono Choices: A Culturally Responsive Teen Pregnancy and STI Prevention Program
The purpose of this study is to determine the impact Pono Choices has among youth for teen pregnancy and STI prevention measures such as: initiation of sexual activity; engagement in high risk sexual behaviors; knowledge of…
- Trial name
- NCT02612324
- Testing
- Pono Choices, Business as Usual
- Volunteers
- 1,783 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Prophylaxis of Avian Influenza
Immunogenicity, Safety and Tolerability of Two Doses of a Pre-pandemic Influenza Vaccine in Participants Aged 6 Months to 17 Years
Evaluate the immune response and reactogenicity of H5N1 vaccination in subjects aged 6 months to 17 years compared to seasonal flu vaccination
- Trial name
- NCT00537524
- Testing
- H5N1 Influenza Vaccine
- Where
- Finland
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Influenza, Virus Diseases
Safety and Immune Response to Recombinant Live-Attenuated Influenza H2N2 Virus Vaccine
In the 20th century, influenza pandemics occurred in 1918, 1957, and 1968, and were associated with significant morbidity and mortality.
- Trial name
- NCT00722774
- Testing
- H2N2 1960 AA ca recombinant vaccine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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