Clinical trials: Preventive Intervention
Knowledge, Attitudes, Practice, Post-exposure Prophylaxis
Comic Intervention for Sexual Violence Prevention and Post-rape Care
In humanitarian settings, sexual and gender-based violence disproportionately impacts women and children. However, there continues to be a lack of evidence regarding both sexual violence prevention and post-rape care…
- Trial name
- NCT04656522
- Testing
- Participatory Comic Intervention
- Where
- 2 sites in Canada, Uganda
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Influenza
The Chloroquine for Influenza Prevention Trial
A randomised controlled trial to determine the efficacy of chloroquine for the prevention of influenza
- Trial name
- CHIP (NCT01078779)
- Testing
- Chloroquine
- Where
- Singapore
- Volunteers
- 1,516 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Haemophilus Influenzae Infection, Vaccines
Safety and Reactogenicity Trial of Vaccine for the Prevention of Infections Caused by Haemophilus Influenzae Type b
Trial purpose is to evaluate the safety, tolerability and reactogenicity of the Vaccine for the prevention of infections caused by Haemophilus Influenzae Type b in volunteers aged 18-50.
- Trial name
- NCT05401305
- Testing
- Vaccine for the prevention of infections caused by Haemophilus influenza type b
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Petersburg Research Institute of Vaccines and Sera
Dementia, Cognitive Impairment
Physical Activity and Cerebral Metabolism in the Elderly: a Randomised Controlled Trial
Physical activity exerts a variety of long-term health benefits in older adults.This randomised controlled trial investigates the effect of a 12-week physical exercise program on the change in cerebral metabolism as assessed with…
- Trial name
- SMART (NCT02343029)
- Testing
- Individualised aerobic exercise training, Waiting Control
- Where
- 2 sites in Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Professor Johannes Pantel
Chemotherapy-induced Peripheral Neuropathy
Efficacy of NAC for the Prevention and Relief of PIPN in Women With Ovarian, Tubal, and Peritoneal Cancer
Ovarian cancer is third most common gynecologic cancer in Thai woman, treatment including surgery followed by chemotherapy. Patient usually received paclitaxel every 3 week for 6 cycles, paclitaxel induce peripheral neuropathy is…
- Trial name
- NCT05539053
- Testing
- N Acetylcysteine A, N Acetylcysteine B
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Stem Cell Transplant, Late Effect
Strength Training as Prevention and Treatment of Late Effects in Long-term Survivors of Pediatric HSCT.
Today the overall survival of childhood cancers has increased to above 85%. This increase is partially caused by treatment with bone marrow transplantation.
- Conditions
- Stem Cell Transplant, Late Effect, Metabolic Syndrome, Cardiovascular Diseases
- Trial name
- STEPS (NCT04922970)
- Testing
- Strength training
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Heart Failure, Caregivers
Heart Failure Resilience Intervention for Caregivers
Heart failure (HF) patients with supportive caregivers have better physical health, emotional health, and quality of life. But caregivers have an increased risk of caregivers' own worsening health and often feel a sense of burden…
- Trial name
- HEROIC (NCT03963583)
- Testing
- HEROIC
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hiv, Adolescent Behavior
A Pragmatic Trial of An Adaptive eHealth HIV Prevention Program for Diverse Adolescent MSM
This pragmatic trial of an HIV prevention program focuses on HIV risk-reduction in men who have sex with men (MSM) ages 13-18. The design is a three-tiered, internet-based HIV prevention intervention series that uses a sequential…
- Conditions
- Hiv, Adolescent Behavior, Sex, Safe
- Trial name
- SMART (NCT03511131)
- Testing
- Queer Sex Ed, Keep It Up, Keep It Up-Control
- Where
- United States
- Volunteers
- 1,306 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cervical Cancer, Intraepithelial Neoplasia
Triage Strategies in Cervical Cancer Prevention
While there is broad consensus that HR-HPV detection is the best available primary screening test, there is no agreement about the most efficient and reliable triage procedure for HR-HPV positive women.
- Trial name
- FRIDA (NCT02510027)
- Testing
- HPV screening and triage tests
- Where
- Mexico
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Scar, Cicatrix
Clinical Safety and Scar Prevention Study of a Topical Antifibrotic Compound FS2.
The study will investigate the safety and effectiveness of daily post surgical scar management, using a moisture-balancing base product containing different amounts of a novel (NCE) antifibrogenic compound FS2, a natural…
- Conditions
- Scar, Cicatrix, Hypertrophic Scar, Skin Graft Scar
- Trial name
- FS2 (NCT04186273)
- Testing
- Fibrosis-Inhibiting-Compound-FS2, Vehicle moisture balancing base
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy Human Volunteers
Effect of Standardized Hibiscus Sabdariffa Tea in Seemingly Healthy Human Volunteers
Hibiscus sabdariffa tea is commonly used all over the world by healthy individual but the tea is also employed by patients in the management of chronic diseases such as hypertension diabetes, high cholesterol, liver disease etc.
- Trial name
- NCT04339283
- Testing
- Standardized Hibiscus sabdariffa tea
- Where
- Nigeria
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Ibadan
Obesity
Family Exergaming: A Research Study Testing a Videogame Intervention to Increase Physical Activity for Families
The purpose of this study is to determine if an interactive game (Dance Dance Revolution/DDR) can promote healthy physical activity for the health of all family members
- Trial name
- NCT00889122
- Testing
- Exergame (DDR)
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- MaineHealth
Suicidal Ideation and Behavior, Suicide
RomSi: Mobile Health Intervention to Enhance Suicide Prevention by Reducing Stigma and Increasing Literacy
Suicide is one of the leading causes of death in Spain, representing a public health crisis that requires urgent and effective solutions.
- Trial name
- NCT06759129
- Testing
- Immediate-use of a mobile health application until completion, Delayed use of a mobile health application until completion
- Where
- Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Alcohol Misuse, Sexual Assault
Positive Change for Sailors
Alcohol use and sexual violence are significant public health issues affecting military personnel. This study includes a pilot randomized control trial of Positive Change© for Sailors, an integrated alcohol and sexual assault…
- Trial name
- +Change Sailor (NCT07858305)
- Testing
- Positive Change© for Sailors
- Where
- 4 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Naval Health Research Center
Alveolitis of Jaw, Alveoli, Teeth; Inflammation
Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery
In the everyday clinical practice the incidence of minor complications is approximately 15-20% of the total number of third molar removals. Alveolitis (dry socket syndrome) may arise in 30-40% of the surgical tooth removals.
- Conditions
- Alveolitis of Jaw, Alveoli, Teeth; Inflammation, Dry Socket, Impacted Third Molar Tooth
- Trial name
- AITS (NCT03741894)
- Testing
- Iodoform, Wound closure using sutures, Chlorhexidine
- Where
- Hungary
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Sex Behavior
Evaluation of Asdzáán Be'eená Teen Pregnancy and Substance Use Prevention Program for Native American Youth and Their Caregiver
The objective of this research study is to evaluate a culturally grounded program among American Indian (AI) female adolescents and their female caregivers.
- Trial name
- NCT04863729
- Testing
- Asdzaan Be'eena Program
- Where
- 2 sites in United States
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Shellfish Poisoning, Paralytic
Prevention of Paralytic Shellfish Poisoning in Subsistence Shellfish Harvest Communities of Southeast Alaska
The purpose of this tribally co-led community-based participatory research in partnership with Sitka Tribe of Alaska was to help prevent Paralytic Shellfish Poisoning (PSP) in children of Southeast Alaska.
- Trial name
- NCT05247229
- Testing
- Middle school education program
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV Infections
Trizivir Vs. Kaletra and Combivir for the Prevention of Mother-to-Child Transmission of HIV
Anti-HIV drug regimens have dramatically improved the rates of prevention of mother-to-child transmission (MTCT) of HIV in developed countries.
- Trial name
- NCT00270296
- Testing
- Trizivir, Lamivudine/Zidovudine, Lopinavir/Ritonavir
- Where
- 4 sites in Botswana
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hypersensitivity
Clinical Efficacy of 10% Arginine Bicarbonate Prophylaxis Paste
The objective of this study is to evaluate the clinical efficacy of a prophylaxis paste containing 10% arginine bicarbonate on dentinal hypersensitivity reduction when applied as a pre-procedure to a professional dental cleaning.
- Trial name
- NCT01072188
- Testing
- Arginine/Calcium Carbonate, Nupro - Fluoride Free
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Body Dissatisfaction
Evaluation of Two Eating Disorders Prevention Interventions in At-Risk Female Students With Body Dissatisfaction
Eating disorders are psychopathologies with serious repercussions on the somatic, psychological and social level. Currently available treatments are unfortunately for now not fully efficient, therefore researchers have…
- Trial name
- HEIDI-BP-HW (NCT04558073)
- Testing
- Body Project (BP), Healthy Weight Program (HW)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
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