Clinical trials: Primary PCI
Chronic Liver Disease
An Observational Study Evaluating Patients With Chronic Liver Diseases Associated With Hepatic Steatosis
Hepatic steatosis may cause inflammation and fibrosis within the liver potentially leading to end-stage liver disease cirrhosis, liver failure and death.
- Trial name
- FALL (NCT05335603)
- Where
- Denmark
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
STEMI, No-Reflow Phenomenon
Insulin Resistance and Its Association With no Reflow Phenomenon After Primary PCI in Type II Diabetic STEMI Patients.
To investigate the relationship between the TyG index, coronary lesion complexity assessed by the SYNTAX score, and the development of the no-reflow phenomenon in STEMI patients with T2DM.
- Conditions
- STEMI, No-Reflow Phenomenon, Diabetic Patient
- Trial name
- NCT07706335
- Testing
- PCI
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
STEMI - ST Elevation Myocardial Infarction
Noninvasive Artificial Venous Stasis for Reperfusion in STEMI
This prospective, randomized study was designed to evaluate whether the noninvasive artificial venous stasis / RE-START procedure, administered prior to primary percutaneous coronary intervention, increases the frequency of…
- Trial name
- RE-START (NCT07689591)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Firat University
Acute Myocardial Infarction
Platelet Indices in Patients Undergoing Primary PCI and Its Prognostic Value
To assess the platelet indices in patients undergoing primary percutaneous coronary intervention and its relation to the severity of coronary artery disease and short term clinical outcomes
- Trial name
- NCT04290949
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
ST Elevation Myocardial Infarction
Cost Effectiveness if Primary PCI Versus Thrombolytic Therapy in Acute STEMI in Assiut University Hospital
Cost effectiveness between PPCI and thrombolytic therapy in STEMI patients without contraindications
- Trial name
- NCT03310437
- Testing
- Primary PCI
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nahed Sameh Zaki
Acute Myocardial Infarction
Bivalirudin in Acute Myocardial Infarction
The purpose of the study is to evaluate the efficacy and safety of bivalirudin in AMI patients with DES. This is a prospective, randomized, single-blind, active drug controlled multicenter clinical research and the study would…
- Trial name
- NCT02897037
- Testing
- Bivalirudin, heparin
- Where
- China
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Shenzhen Salubris Pharmaceuticals Co., Ltd.
Myocardial Infarction
Complete Lesion Versus Culprit Lesion Revascularization
To investigate the clinical outcomes of acute myocardial infarction (AMI) patients with multivessel disease undergoing percutaneous coronary intervention (PCI) either in infarct-related artery only or in multivessel in Drug…
- Trial name
- COCUA (NCT01180218)
- Testing
- complete revascularization, Culprit revasularization
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
ST Elevation (STEMI) Myocardial Infarction
LA Strain in Predicting Early Complication in STEMI After PPCI
The goal of this observational study To evaluate the predictive value of left atrial strain for in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing PPCI.
- Trial name
- NCT07263282
- Testing
- 2D echocardiography
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
ST Elevation Myocardial Infarction
Effect of Upstream Treatment With High Intensity Statin on the Outcomes of STMI Patients Treated With PPCI
Effect of upstream treatment with high intensity statin on the outcome of ST segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention
- Trial name
- NCT04754789
- Testing
- Atorvastatin, Aspirin
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN)
Beyond the Mehran Risk Score: Predictive Value of Total Ischemic Time for Contrast-Induced Nephropathy in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.
Contrast-Induced Nephropathy (CIN) is a serious complication following primary percutaneous coronary intervention (PCI) in patients presenting with acute ST-segment elevation myocardial infarction (STEMI).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN), Acute Kidney Injury
- Trial name
- NCT07826572
- Testing
- Total Ischemic Time Evaluation
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Slow Breathing, Acute Myocardial Infarction
The Effect of Slow Breathing Exercise Applied to Patients on Pulse, Blood Pressure and Quality of Life
This study was designed as a randomized controlled experimental type in order to determine the effect of slow breathing exercise applied after the procedure on heart rate, blood pressure and quality of life in patients who…
- Trial name
- NCT06098222
- Testing
- Slow breathing exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Primary Percutaneous Coronary Intervention
Influence Of Incomplete Revascularization on Long-Term Outcomes After Primary Percutaneous Coronary Intervention (PPCI)
evaluate the influence of incomplete revascularization during the index hospitalization on in-hospital and long-term outcomes in STEMI patients undergoing PPCI in Assiut University heart hospital.
- Trial name
- NCT04332250
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Amany Edward Ramzy
ST Elevation (STEMI) Myocardial Infarction
Bempedoic Acid in PPCI Impact on Clinical Outcome and Inflammatory Markers
Bempedoic acid in PPCI
- Trial name
- NCT07129850
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
No-Reflow Phenomenon
the No-reflow in Diabetic Patients Treated With Primary Percutaneous Coronary Intervention (PCI)
1- to find metabolic factors that correlate with the development of no reflow phenomenon that may help prevent its occurrence .
- Trial name
- NCT04835974
- Testing
- 1- LDL-C (low-density lipoprotein cholesterol)| and HDL-C(high-density lipoprotein cholesterol) Ratio. 2- Glycemia will be assessed : RBS ( random blood sugar ) . 3- S
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
ST Elevation Myocardial Infarction (STEMI)
IMPROVE-STEMI: pPCI Plus Low-dose r-SK in STEMI
This is a multicenter, prospective, pragmatic, randomized controlled trial (IMPROVE-STEMI) aiming to evaluate the efficacy and safety of intracoronary low-dose recombinant streptokinase combined with primary percutaneous coronary…
- Trial name
- IMPROVE-STEMI (NCT07875179)
- Testing
- Recombinant Streptokinase
- Where
- China
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Myocardial Infarction, Percutaneous Coronary Intervention
Circulating PRCP in STEMI Patients Undergoing Primary PCI
Purpose: The purpose of this study is to evaluate the impact of acute ST-segment elevation myocardial infarction (STEMI) and primary percutaneous coronary intervention (PCI) on circulating prolylcarboxypeptidase (PRCP) level and…
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, PRCP
- Trial name
- NCT02772133
- Testing
- Primary PCI
- Where
- 4 sites in China
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Cystic Fibrosis, Pulmonary Fibrosis
Role of Genetic Factors in the Development of Lung Disease
This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease.
- Conditions
- Cystic Fibrosis, Pulmonary Fibrosis, Tuberous Sclerosis, Asthma
- Trial name
- NCT00001532
- Where
- 2 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
ST Elevation (STEMI) Myocardial Infarction
Microcirculation In Acute Coronary Syndromes
In this mechanistic pilot study in 40 patients the investigators will compare the findings in patients treated with very early high dose statin therapy with historic controls from the KOMPIS study published in EHJ 200925.
- Trial name
- MICROS (NCT01382472)
- Testing
- Rosuvastatin, Simvastatin
- Where
- 3 sites in Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Primary Percutaneous Coronary Intervention
Thin Versus Thicker Strut Thickness Stents in Primary Percutaneous Intervention
1. To evaluate clinical safety of the device in terms of Deaths, any stroke and Myocardial Infarction up to 1 year in both study groups to prove non inferiority of biomime stent 2.
- Trial name
- NCT06914089
- Testing
- The BioMime is an ultra-thin strut (65 µm) SES that uses a cobalt-chromium platform with a unique hybrid design of open cells in the mid segment and closed cells at the edges
- Where
- Egypt
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Assiut University