Clinical trials: Priming
Aortic Aneurysm, Abdominal
Post-Approval Study of the Ovation™/Ovation Prime™ Abdominal Stent Graft System
The Post-Approval Study (PAS) will evaluate the "real world" data on the Ovation™/Ovation Prime™ Abdominal Stent Graft System along with the long-term data collected from the IDE cohort to monitor the long-term safety and…
- Trial name
- NCT01980901
- Testing
- Ovation™/Ovation Prime™ Abdominal Stent Graft System
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- TriVascular, Inc.
Sepsis, Septic Shock
PRIME Sepsis Trial: Early Sepsis Detection in the Emergency Department Using Presepsin and Immature Granulocytes
Early identification and timely intervention for sepsis in the emergency department (ED) are critical for improving patient outcomes.
- Trial name
- NCT07822412
- Where
- Taiwan
- Volunteers
- 699 people
- Sponsor
- Chang Gung Memorial Hospital
Ischemic Stroke, Hemorrhagic Stroke
Aerobic Exercise and Cognitive Training in Patients With Stroke
The goal of this clinical trial is to test the effects of aerobic exercise and BDNF on patients with ischemic and hemorrhagic stroke during a computerized cognitive training. The main questions it aims to answer are: 1.
- Trial name
- NCT05735405
- Testing
- Neuropsychological evaluation, BDNF evaluation, Pedaling as a moderate intensity aerobic exercise
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Oocyte Donors, Oocyte Donation
Luteal Phase Ovarian Stimulation With Follitropin Delta and Dydrogesterone
The last decade has shown a progressive scientific interest for new strategies to improve the outcomes of controlled ovarian stimulation (COS).
- Trial name
- LadyDe (NCT05521828)
- Testing
- Follitropin delta (Rekovelle), Duphaston, GnRH agonist (Gonapeptyl)
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Aphasia
Sentence Production Training in Aphasia
This project focuses on developing a novel treatment for sentence production and comprehension in aphasia, using implicit priming.
- Trial name
- NCT05415501
- Testing
- Sentence training
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Purdue University
Castration Levels of Testosterone, Castration-Resistant Prostate Carcinoma
177Lu-PSMA-617 and Pembrolizumab in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
This phase Ib trial studies the dose and schedule of 177Lu-PSMA-617 and pembrolizumab in treating persons with castration-resistant prostate cancer that has spread to other places in the body.
- Conditions
- Castration Levels of Testosterone, Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Prostate Adenocarcinoma
- Trial name
- NCT03805594
- Testing
- Lutetium Lu 177-PSMA-617, Pembrolizumab
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of California, San Francisco
Acquired Immunodeficiency Syndrome
Safety and Immunogenicity of Recombinant HIV Vaccines for HIV/AIDS
This is a randomized, double-blind placebo-controlled dose-escalation clinical trial to evaluate the safety and the immunogenicity of DNA and modified vaccinia virus Ankara (MVA) HIV-1 vaccines in subjects receiving stable highly…
- Trial name
- NCT01881581
- Testing
- Saline Solution, D-GPEi, M-GPE
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Centers for Disease Control and Prevention, China
Aortic Stenosis
OpSens PRIME CLASS
In this study it is aimed to determine the diagnostic value of physiological measurements in the presence of aortic stenosis, and whether these are more accurate than angiographic assessment.
- Trial name
- NCT05070130
- Testing
- dPR and FFR
- Where
- 5 sites in Spain
- Volunteers
- 32 people
- Sponsor
- Opsens, Inc.
Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 5
A Communication-Priming Intervention to Improve Shared Decision-Making Between Older Adults With Advanced CKD and Clinicians
To achieve the goal of reaching consensus about the preferred treatment option that best aligns with the goals and values of patients, the investigators developed a 'CKD Jumpstart- Tips" priming tool tailored for older adults…
- Trial name
- NCT06799936
- Testing
- "CKD Jumpstart- Tips" priming intervention
- Where
- Hong Kong
- Volunteers
- 280 people
- Sponsor
- The University of Hong Kong
Malaria, Matrix M
Adjuvanting Viral Vectored Malaria Vaccines With Matrix M
ChAd63 METRAP and MVA METRAP are investigational vaccines for malaria which have been studied in clinical trials for 4 years, and 10 years, respectively.
- Trial name
- NCT01669512
- Testing
- Control Regimen, Low Dose Matrix M Regimen, Standard Dose Matrix M Regimen
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Myopia Progression
Prospective Research on the Intervention of Myoless2.0 Effectiveness (PRIME) in Pediatric Population
The Goal of the study is to evaluate the rate of myopia progression with open ring myopia control spectacle lens designs compared to a commercial peripheral plus myopia control spectacle lens (CML) in European children with…
- Trial name
- PRIME (NCT07394556)
- Testing
- myopia control lens
- Where
- 3 sites in Portugal, Spain and 1 more
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Indizen Optical Technologies, S.L.U.
Chronic Hepatitis B
Dose-Escalation Prime/Boost Therapeutic Vaccination Study Of 2 Chimp Adenoviral Vectors in Adults With Chronic HBV On Nucleos(t)Ide Therapy
This Phase 1b clinical study is a multi-center, open-label, dose escalation, prime only, and prime plus boost therapeutic vaccination study of 2 distinct chimpanzee adenoviral vectors (AdC6 and AdC7), containing parts of…
- Trial name
- NCT06070051
- Testing
- VRON-0200-AdC6, VRON-0200-AdC7, VIR-2218
- Where
- 3 sites in Hong Kong, New Zealand
- Volunteers
- 35 people
- Sponsor
- Virion Therapeutics
Cervical Laceration, Adverse Effects
Oral Misoprostol for Cervical Priming Before Hysteroscopy
A randomized, double blind study to compare 200 and 400 mcg misoprostol for cervical preparation before hysteroscopy.
- Trial name
- NCT02159911
- Testing
- Misoprostol administered orally one hour before surgery
- Where
- Lebanon
- Volunteers
- 84 people
- Sponsor
- Saint-Joseph University
Psoriasis
A Priming Intervention to Increase Patient Willingness to Use Injectables for the Management of Psoriasis
Biologic medications have revolutionized the treatment of inflammatory diseases such as moderate-to-severe psoriasis. Though very effective with an excellent safety profile, patients may be apprehensive about choosing a biologic…
- Trial name
- NCT03465696
- Testing
- Group #2 (Intervention), Group #3 (Intervention)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Wake Forest University Health Sciences
Hemorrhagic Fever, Ebola
Safety, Tolerability and Immunogenicity Study of 3 Prime-boost Regimens for Ebola Vaccines Ad26.ZEBOV/MVA-BN-Filo in Healthy Adults, Children and Human Immunodeficiency Virus Positive (HIV+) Adults
The purpose of this study is to assess the safety, tolerability and immunogenicity of three heterologous prime-boost regimens for Ebola vaccines Ad26.ZEBOV and MVA-BN-Filo.
- Trial name
- NCT02564523
- Testing
- Ad26.ZEBOV, MVA-BN-Filo
- Where
- 7 sites in Burkina Faso, Côte d’Ivoire and 2 more
- Volunteers
- 1,075 people, healthy volunteers welcome
- Sponsor
- Janssen Vaccines & Prevention B.V.
Outpatient Mechanical Cervix Priming
Outpatient Foley Cervix Priming
The aim was to conduct a non-blinded prospective randomized study at a tertiary hospital. Inclusion criteria: term pregnancy with a single fetus in cephalic presentation, Bishop score < 6, gestational age > 41 weeks or medical…
- Trial name
- NCT02842879
- Testing
- Outpatient Foley cervix priming
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital de Santa Maria, Portugal
Post-traumatic Stress Disorder (PTSD), Emotional Contagion
Attachment and Post-Traumatic Stress Disorder in Military Personnel: Characterization of the French Military Population, Exploration of Biopsychosocial Factors, and Study of the Impact of Security Priming on Emotional Contagion Capacities
Post-traumatic stress disorder (PTSD) is a pathology that impairs the quality of life of sufferers. In military personnel, it can lead to military incapacity.
- Trial name
- AT-HOME (NCT06996275)
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Healthy
A Safety and Immunogenicity Study of Heterologous Prime-Boost Ebola Vaccine Regimens in Healthy Participants
The purpose of this study is to test the safety and immunogenicity of MVA-BN-Filo and Ad26.ZEBOV as heterologous prime-boost vaccine regimens in healthy adult participants.
- Trial name
- NCT02313077
- Testing
- MVA-BN-filo, Ad26. ZEBOV
- Where
- United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Crucell Holland BV
Coronary Artery Disease, Myocardial Infarction
Amsterdam Investigator-initiateD Absorb Strategy All-comers Trial
To evaluate the efficacy and performance in an all-comers contemporary population of the ABSORB bioresorbable vascular scaffolds (BVS) strategy versus the XIENCE family (XIENCE PRIME or XIENCE Xpedition) everolimus eluting…
- Trial name
- AIDA (NCT01858077)
- Testing
- ABSORB BVS™, XIENCE™
- Where
- 5 sites in Netherlands
- Volunteers
- 1,845 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Coronary Artery Disease, Aortic Valve Disease
Comparison of Priming Constituents in Patients Undergoing CPB Assisted Cardiac Surgery: HES 130/0.4 or Albumin 5%
The purpose of the study is to determine which priming fluid is the safest for use for priming the heart-lung machine used during cardiopulmonary bypass for patients undergoing cardiac surgery.
- Conditions
- Coronary Artery Disease, Aortic Valve Disease, Mitral Valve Disease
- Trial name
- NCT01849757
- Testing
- prime crystalloid, Human Albumin, Voluven
- Where
- Canada
- Sponsor
- University of Saskatchewan