Clinical trials: Prognathism
Skeletal Malocclusion, Class III Malocclusion
The Effect of Splint Usage in Laterognathic Cl III Orthognathic Surgery Patients
It is crucial to maintain the anatomic condylar positions during orthognathic surgery. Condylar positions are affected directly under general anesthesia because of joint and muscle relaxation.
- Conditions
- Skeletal Malocclusion, Class III Malocclusion, Laterognathia
- Trial name
- TMJ (NCT05216874)
- Testing
- Oclusal Splint
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Bezmialem Vakif University
Malocclusion, Angle Class III
Evaluation of Different Anchorage-supported Appliances and Expansion Procedures for Face Mask Treatment
The purpose of this study is to assess and compare the effect of two appliances (Hybrid-Hyrax expander/ Bonded rapid maxillary expander (RME)) supported by different anchorage units and two different expansion procedures (routine…
- Trial name
- NCT06244563
- Testing
- Face mask with Hybrid-Hyrax, Face mask with Bonded RME, Alternative Rapid Maxillary Expansion and Contraction Protocol (Alt-RAMEC)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Class III Malocclusion, Skeletal Malocclusion
Comparison of Skeletal Anchorage Versus Conventional Tooth-Borne Face Mask Therapy Following the Alt-RAMEC Protocol
This study investigated two different methods of maxillary protraction in growing patients with skeletal Class III malocclusion characterized by maxillary deficiency.
- Conditions
- Class III Malocclusion, Skeletal Malocclusion, Maxillary Deficiency
- Trial name
- MiniFM (NCT07279662)
- Testing
- Skeletal Anchorage Supported Maxillary Protraction, Tooth-Borne Maxillary Protraction Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Murat Kaan Erdem
Retrognathism, Prognathism
Pharmacological Treatment on the Recovery of Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy
The bilateral sagittal split osteotomy (BSSO) of the mandible is one of the most used surgical techniques to achieve a harmonious jaw relation in the context of orthognathic surgery.
- Conditions
- Retrognathism, Prognathism, Orthognathic Surgery, Neurosensory Disorder
- Trial name
- NCT05536596
- Testing
- Orthognathic Surgery, Melatonin 10 MG Oral Tablet, Hydroxycobalamin
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Anterior Crossbite, Class III Malocclusion
Evaluation of the Treatment Effects of Tooth Borne Versus Bone-anchored Protraction Procedures in Class III Patients With Maxillary Deficiency
The aim of this prospective randomized controlled clinical study is to compare the effects of bone-anchored and tooth borne maxillary protraction on dentofacial structures in skeletal Class III patients.
- Conditions
- Anterior Crossbite, Class III Malocclusion, Maxillary Deficiency
- Trial name
- NCT04863404
- Testing
- Face mask with hybrid-hyrax, Face mask with conventional bonded RME
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Facial Asymmetry, Retrognathism
Efficacy of Intravenous Iron Therapy in Maintaining Hemoglobin Concentration on Patients Undergoing Bimaxillary Orthognathic Surgery
The aim of this study is to evaluate the effect of Intravenous iron isomaltoside on maintaining hemoglobin concentration in patients undergoing bimaxillary orthognathic surgery.
- Conditions
- Facial Asymmetry, Retrognathism, Prognathism
- Trial name
- NCT03094182
- Testing
- Iron Isomaltoside 1000, Normal saline
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Prognathism, Retrognathism
Natural History of Craniofacial Anomalies and Developmental Growth Variants
Background: Some head and facial abnormalities are rare and present at birth. Others are more common, and may not show up until puberty. These conditions have different causes and characteristics.
- Conditions
- Prognathism, Retrognathism, Dentofacial Deformities
- Trial name
- NCT02639312
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Malocclusion, Angle Class III, Extraoral Traction Appliances
Comparison of Customized and Standard Facemasks for Early Treatment of Class III Malocclusion
The aim of the study is to compare a customized facemask for the treatment of Class III malocclusion in the prepubertal growing patient (patients between the ages of 5 and 12 years) versus a standard commercial facemask.
- Trial name
- NCT06402656
- Testing
- Customized facemask, Standard facemask
- Volunteers
- 24 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Class III Malocclusion
Evaluating the Effectiveness of the Lower-Clear-Plate-Based Intermaxillary Traction
Patients at the Orthodontic Department of the University of Damascus Dental School will be examined, and subjects who meet the inclusion criteria will be included.
- Trial name
- NCT06596239
- Testing
- lower-clear-plate-based intermaxillary traction (LCP-IMT), Removable mandibular retractor (RMR)
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Multiple Sclerosis
Motor Evoked Potentials With Modified Facilitation Technique
Investigating the change in Test- Retest- reliability in healthy individuals when applying a modified easy to use facilitation technique compared to standard facilitation technique and analyzing sensitivity and specificity in…
- Trial name
- EP-F (NCT03646929)
- Testing
- MEP using standard facilitation technique, MEP using modified facilitation technique
- Where
- Switzerland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Malocclusion, Angle Class III
Periodontal Ligament Stress Level and Tooth Movement
Orthodontic treatment requires application of force systems to individual teeth or groups of teeth, which results in a cellular response with periodontal ligament (PDL) and alveolar bone remodeling.
- Trial name
- NCT00099814
- Testing
- Two different loop designs which deliver distinctive forces
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Malocclusion, Angle Class I, Malocclusion, Angle Class II
3D Printed Occlusal Splints for Intraoperative Use
A 3D printed intraoperative occlusal splint is a custom-made biocompatible resin guide that allows surgeons properly align a patient's upper and lower dentition during surgery.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- NCT07079111
- Testing
- Formlabs 3D printed occlusal splint, Industry made occlusal splint
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins University
Face Mask, Rapid Maxillary Expansion
Class III Malocclusion and ALT-RAMEC
Diverse viewpoints exist regarding the correlation between the conventional rapid maxillary expansion (RME) and facemask approach and the alternative RME and facemask hybrid technique (Alt-RAMEC) in terms of the degree of…
- Conditions
- Face Mask, Rapid Maxillary Expansion, Maxillary Retrognathism
- Trial name
- NCT05913076
- Testing
- Delaire Face Mask (M0774-01, Leone S.p.A., Florence, Italy) for first group, Delaire Face Mask (M0774-01, Leone S.p.A., Florence, Italy) for second group, Delaire Face Mask (M0774-01, Leone S.p.A., Florence, Italy) for third group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trakya University
Maxillary Prognathism
En-mass Retraction by KILBON Versus CAT Appliances
en-mass retraction by lingual retractor versus clear alighner therapy
- Trial name
- NCT06366737
- Testing
- KILBON Appliance, CAT appliance
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skeletal Class III Malocclusion
Figuring Out the Genetic Mutations That Lead to Lower Jaw Advancement More Than the Upper Jaw
Purpose of the Research: To reveal the genetic cause for the occurrence of Class III malocclusion, or what may be described as a reverse bite (underbite). Introduction and Detailed Procedures for the Patient (Work Plan): 1.
- Trial name
- NCT07749638
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Cairo University
Jaw Protrusions
The Effectiveness of Modified 3D Printed Customized Facemask Appliance for Treatment of Class III Malocclusion
A randomized clinical trial to introduce a modified 3D printed customized maxillary protraction facemask and evaluate its efficacy in comparison with the conventional maxillary protraction facemask therapy in correction of Class…
- Trial name
- NCT06250127
- Testing
- Modified 3D printed facemask, Conventional facemask appliance
- Where
- 2 sites in Iraq
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Skeletal Class III Malocclusion
Surgery-First Orthognathic Surgery in Skeletal Class III Treatment
This study evaluates the efficacy and stability of the "Surgery-First" approach (SF approach) in treating patients with skeletal Class III malocclusion, utilizing a combined retrospective and prospective data collection method.
- Trial name
- NCT07433842
- Testing
- Surgery-First Orthognathic Surgery
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Hanoi Medical University
Class III Malocclusion
Palatal Versus Buccal Protraction Using Plates Assisted With Facemask in Growing Class III Patients
to compare Palatal and buccal protraction using plates assisted with facemask in growing class III patients
- Trial name
- NCT06452368
- Testing
- facemask
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Malocclusion, Angle Class II, Malocclusion, Angle Class III
Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time
The purpose of this study is to find out if 3D printed patient-specific titanium plates improve surgical accuracy and decrease operative time compared to milled patient-specific titanium plates in patients having Le Fort I…
- Conditions
- Malocclusion, Angle Class II, Malocclusion, Angle Class III, Dentofacial Deformities, Osteotomy, Le Fort I
- Trial name
- TiPlateRCT (NCT07841067)
- Testing
- 3D-Printed Patient-Specific Titanium Plates, Milled Patient-Specific Titanium Plates
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Future University in Egypt
Class III Malocclusion
Corticotomy-Assisted Class III Elastic Applications
This prospective randomized clinical study aimed to evaluate the effectiveness of corticotomy-assisted maxillary protraction with three different miniplate and intermaxillary elastic applications after corticotomy in patients…
- Trial name
- CACIIIEA (NCT06763900)
- Testing
- Skeletal anchorage and intermaxillary elastic assisted maxillary protraction
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- TC Erciyes University