Clinical trials: Prosthetic
Bone Loss in Jaw
Immediate Loading With Provisional Prosthetic Restoration by Means of One Abutment at One Time and Temporary Abutment
This will be a prospective, randomized, controlled, single center clinical trial with 1 year enrollment period, surgical and prosthetic rehabilitation with 1-year post-loading follow-up.
- Trial name
- NCT05668494
- Testing
- immediate loading of implants
- Where
- Serbia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Prosthesis Related Infections
Biodistribution and Dosimetry Evaluation of [124I]FIAU
This protocol will evaluate the biodistribution and dosimetry of [124I]FIAU in both healthy volunteers and patients with prosthetic joint infections.
- Trial name
- NCT01337466
- Testing
- [124I]FIAU
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BioMed Valley Discoveries, Inc
Hemiparesis
Improving Myoelectric Prosthetic and Orthotic Limb Control
The purpose of this study is to improve control of myoelectrically-controlled advanced orthotic devices (an exoskeleton device that use the body's muscle signals to drive movements of a robotic brace) by using advanced predictive…
- Trial name
- NCT05509101
- Testing
- commercially available control algorithm, experimental control algorithm
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Utah
Prosthesis and Implants, Surgical Site Infection
Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-III)
The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if PDT has an effect on bacterial skin colonization in order to improve skin antisepsis…
- Conditions
- Prosthesis and Implants, Surgical Site Infection, Prosthetic Joint Infection, Postoperative Wound Infection Deep Incisional Surgical Site
- Trial name
- NCT05676801
- Testing
- Photodynamic Therapy
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hernia of Abdominal Wall, Incisional Hernia
"BP as a New Device for Surgery and Solid Cancer and Hematopoietic System Tumors Treatment. Effects of BP Implantation"
Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias in humans, in laparotomic procedures and as a new device…
- Trial name
- DM159 (NCT02328352)
- Testing
- BP selfstanding felt, PP mesh, BP intraperitoneal mesh
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Edentulous Jaw
Precision of Complete-arch Digital Implant Impressions With Intraoral Scanning Versus Photogrammetry
The goal of this cross-over clinical trial is to investigate the precision of digital implant impressions using an intraoral scanner and photogrammetry in obtaining complete-arch implant-supported scans.
- Trial name
- NCT05972148
- Testing
- Digital scanning, Photogrammetry
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- William Negreiros
Joint Infection
Can Intraosseous Antibiotics Improve the Results of Irrigation & Debridement and Prosthetic Retention for PJI?
Purpose of Study: In order to improve upon the variable results seen in irrigation and debridement for periprosthetic infection, we ask if the use of intraosseous regional administration of antibiotics at the time of irrigation…
- Trial name
- NCT03713528
- Testing
- Intraoperative Intraosseous Vancomycin
- Where
- 10 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- OrthoCarolina Research Institute, Inc.
Amputation
Enhanced Auto-Diagnostic Adaptive Precision Trainer for Myoelectric Prosthetic Users
The eADAPT training consists of a variety of mobile games played on a mobile app (phone or tablet). A band is worn on the residual limb. Participants use muscle activation to send signals to execute certain movements in the game.
- Trial name
- eADAPT (NCT04238533)
- Testing
- eADAPT training, Conventional training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Prosthetic-joint Infection, Arthroplasty Complications
Knee Prosthetic Joint Infection Antibiotic Elution
Patients presenting with prosthetic joint infections of a total knee replacement who are treated with an antibiotic spacer will be observed prospectively for their response to treatment and antibiotic elution profiles will be…
- Trial name
- NCT06023238
- Testing
- Treatment of Chronic TKA PJI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Tissue Adhesives
Quantifying Adhesive Residue on Skin Following Removal of Maxillofacial Prosthetic Adhesives: An In Vivo Study
This pilot interventional in vivo study aims to quantitatively evaluate and compare the amount of adhesive residue left on the skin following removal of extraoral maxillofacial prosthetic adhesives.
- Trial name
- ARMS (NCT07647458)
- Testing
- Secure Adhesive Regular,, Secure Adhesive Extra Strength, Daro Adhesive Regular
- Where
- India
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Amrita Vishwa Vidyapeetham
Knee Osteoarthritis
Anatomic Congruent Prosthetic Knee Design
This double-blinded randomized control study will use kinematic and kinetic measures to compare an anatomical congruent prosthetic knee design to a standard prosthetic knee design.
- Trial name
- NCT03633201
- Testing
- Cruciate Retaining, Medial Congruent
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Dental Restoration, Dental Implant
Prosthetic Outcomes and Clinical Performance of Implant Supported Zirconia Crowns
To compare biological, technical, radiographic, and patient-reported outcomes of two types of monolithic zirconia crowns screw-retained to implant.
- Trial name
- NCT06417632
- Testing
- Graded Zirconia Crown, Conventional Zirconia Crown
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Amputation Stumps, Amputees
Moisture Management Liner Effectiveness Study
The comfort and fit of the residual limb within a prosthetic socket are of primary concern for many amputees. The residual limb is typically covered by non-breathable and non- thermally conductive materials that can create a warm…
- Conditions
- Amputation Stumps, Amputees, Amputation, Lower Limb Deformities, Congenital
- Trial name
- NCT04427007
- Testing
- Moisture Management Liner, Control Liner
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Complete Edentulism, All-on-4
OT-Bridge System Versus Multiunit Abutment for Mandibular All On-4 Screw Retained Prostheses.
This study aims to compare two different prosthetic systems used in mandibular full-arch implant-supported fixed prostheses (All-on-4).
- Conditions
- Complete Edentulism, All-on-4, Implant Supported Prosthesis, Multiunnit Abutments
- Trial name
- NCT07701200
- Testing
- OT-Bridge, Multiunit
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Amputation
Movement and Sensation for Advanced Prosthetic Hands
The purpose of this study is to learn more information about nerves. This study is also designed to learn how the information in nerves could be used to develop new prosthetic devices.
- Trial name
- NCT03259386
- Testing
- Microelectrode array
- Where
- 2 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Amputation
Optimizing Prosthetic and Bicycle Fit for Veterans With Transtibial Amputations
Bicycling is a promising form of low-impact exercise that could prevent/treat Type 2 diabetes. However, Veterans with transtibial amputations (TTAs) may not effectively utilize bicycling for rehabilitation and exercise due to…
- Trial name
- BestBikeFit (NCT03828331)
- Testing
- Prosthetic/Bicycle Configuration
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Blindness
A Study to Evaluate the BrainPort Vision Device in Individuals Blinded by Traumatic Injury
The BrainPort V200 Device is a wearable, non-surgical, prosthetic device intended for people who are profoundly blind. The BrainPort V200 translates images captured by a digital camera into electro-tactile stimulation presented…
- Trial name
- NCT02393118
- Testing
- BrainPort V200 Device
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wicab
Umbilical Hernia, TARUP
rTARUP: Long-term Analysis
The aim of the study is to assess the recurrence rate and potential long-term complications, at least 48 months, after a robotic assisted transabdominal retromuscular approach (rTARUP technique) for the repair of an umbilical…
- Conditions
- Umbilical Hernia, TARUP, Robotic Abdominal Wall Surgery
- Trial name
- rTARUP FU (NCT05939206)
- Testing
- rTARUP
- Where
- Belgium
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Implant-supported Single Crowns, Osseointegration
Influence of Prosthetic Characteristics of Implant-Supported Crowns on Peri-implant Health and Osseointegration: A Comparison Between Digital and Conventional Workflows
The objective of this prospective cohort study is to evaluate marginal bone loss and peri-implant health in patients with single dental implants requiring prosthetic rehabilitation, comparing conventional and digital methods for…
- Conditions
- Implant-supported Single Crowns, Osseointegration, Peri-Implant Health
- Trial name
- NCT07897487
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Lower Limb Amputation Below Knee, Diabetes (DM)
Skin Temperature Perception and Prosthetic Thermoregulation
To protect against excessive body temperatures, local thermoregulatory mechanisms include temperature sensory nerves (responsive to warm or cool stimuli) and vasomotors (muscles that constrict or dilate blood vessels).
- Conditions
- Lower Limb Amputation Below Knee, Diabetes (DM), Skin Temperature Change, Vascular Reactivity
- Trial name
- NCT07215442
- Testing
- Warming stimulus starting at 30 C initial temperature, Warming stimulus starting at 32 C initial temperature, Warming stimulus starting at 34 C initial temperature
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- VA Puget Sound Health Care System