Clinical trials: Protein Digestion
Cancer Patients Receiving Chemotherapy or Chemoradiotherapy
Nutrition Intervention During Chemotherapy
Weight loss and muscle wasting commonly occurs in patients with cancer, negatively influencing their quality of life, treatment response and survival.
- Trial name
- NCT01871350
- Testing
- Daily intake for 10 weeks (+/- 2 weeks)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Main Focus: Gluten and Starch Digestibility
GlutDigest - Pilot Study
This is a pilot, feasibility study to evaluate, test and optimize sample analysis procedures and protocols before the full-scale, crossover study is conducted.
- Trial name
- GlutDigestP (NCT04489836)
- Testing
- Glutalytic®, DE111®, Meal A
- Where
- Ireland
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Deerland Enzymes
Diet Habit, Gall Stone
Are There Dietary Factors Affecting the Development of Pancreatitis in Patients With Gallstones?
The most common cause of acute pancreatitis is gallstones. It is known that diet and obesity play a role in the formation of gallstones.
- Conditions
- Diet Habit, Gall Stone, Pancreatitis
- Trial name
- NCT05142657
- Testing
- diet survey
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Training and Research Hospital
The Null Hypothesis is That Food Rheology Will Have no Effect on These Indices, The Alternate Hypothesis is That Increased Mechanical Stimulation Will Result in Stronger Satiation/Satiety and Reduced Energy Intake
Effects of Gum Chewing on Appetite and Digestion
One obvious property difference between energy-yielding beverages and solid foods is the oral mechanical processing required to prepare the two food forms for swallowing.
- Conditions
- The Null Hypothesis is That Food Rheology Will Have no Effect on These Indices, The Alternate Hypothesis is That Increased Mechanical Stimulation Will Result in Stronger Satiation/Satiety and Reduced Energy Intake, It is Hypothesized That the Effects of Mastication Will be Less Evident in Obese Compared to Lean Individuals
- Trial name
- NCT01070212
- Testing
- soft gum, firm gum, no gum
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Purdue University
Breast Cancer, Lung Cancer
Real World Treatment Experience of Patients With Breast, Lung, or GI Cancer or Multiple Myeloma Using Remote Symptom Monitoring
The Carevive registry collects patient characteristics, patient symptoms, and treatment experience data from patients receiving cancer treatment for breast, lung, GI or multiple myeloma.
- Conditions
- Breast Cancer, Lung Cancer, Gastrointestinal Cancer, Multiple Myeloma
- Trial name
- NCT05587972
- Testing
- survey
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Carevive Systems, Inc.
Gastrointestinal Symptoms in Young Infants
Milk-induced Gastrointestinal Symptoms in Infants
Various digestive manifestations are common in infants less than 6 months and have a significant impact on morbidity and quality of life of the family.
- Trial name
- NCT01684319
- Testing
- Formula milk free of cow's milk protein
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University Hospital, Geneva
Chronic Hepatitis B
A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
This study is an open-label, ascending dose phase 1a trial to assess the safety and immunogenicity of a heterologous protein prime/MVA boost therapeutic hepatitis B vaccine
- Trial name
- NCT05727267
- Testing
- HEPLISAV B; TherVacB, TherVacB
- Where
- 2 sites in Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
B Cell Lymphoma, NHL, Adult
SynKIR-310 for Relapsed/Refractory B-NHL
This first-in-human (FIH) trial is designed to assess the safety, feasibility and preliminary efficacy of a single intravenous (IV) dose of SynKIR-310 administered to participants with relapsed/refractory B-NHL.
- Conditions
- B Cell Lymphoma, NHL, Adult, Mantle Cell Lymphoma, Relapsed Non-Hodgkin Lymphoma
- Trial name
- NCT06544265
- Testing
- SynKIR-310
- Where
- 5 sites in United States
- Volunteers
- 36 people
- Sponsor
- Verismo Therapeutics
Non-melanomatous Skin Cancer, Pancreatic Cancer
Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Conditions
- Non-melanomatous Skin Cancer, Pancreatic Cancer, Small Intestine Cancer, Testicular Germ Cell Tumor
- Trial name
- NCT00899132
- Testing
- in situ hybridization, protein expression analysis, immunologic technique
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Milk, Digestion
The Effect of Breast Milk Smell on Nutrition in Preterms
The study was planned to determine the effect of breast milk odor applied during gavage feeding on early feeding cues of preterm newborns, the transition time to oral feeding and abdominal perfusion.
- Conditions
- Breast Milk, Digestion, Nutrition, Smell Stimulation
- Trial name
- NCT04843293
- Testing
- Olfactory stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Liver Disease
A Study to Assess the Effect of Severe Hepatic Impairment on the Pharmacokinetics of Intravenous Conivaptan
The purpose of this study is to assess the pharmacokinetics and safety of a 48-hour continuous infusion of conivaptan in subjects with severe liver impairment compared to subjects with normal liver function.
- Trial name
- NCT01370148
- Testing
- conivaptan hydrochloride
- Where
- 3 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Cumberland Pharmaceuticals
Drug Induced Liver Injury
Acetaminophen Adduct Formation in Non-Drinkers Taking Therapeutic Doses of Acetaminophen for Ten Consecutive Days
Acetaminophen is commonly used to treat fever or pain. Your body clears acetaminophen by processing it in the liver. During the processing, some of the acetaminophen may bind to proteins in the liver.
- Trial name
- Non-Drinker (NCT00616018)
- Testing
- acetaminophen
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kennon Heard
Mucositis, Multiple Myeloma
Analysis of Oral Mucositis in Patient's Undergoing Melphalan Conditioning and Autologous Stem Cell Transplant
This is a pilot study to explore and identify changes in molecular processes within the oral mucosa that are associated with the development of oral mucositis (OM) in patients treated with Melphalan who undergo autologous…
- Conditions
- Mucositis, Multiple Myeloma, Amyloidosis, Oral Mucositis
- Trial name
- NCT02589860
- Testing
- Melphalan kinetic study, Oral bacterial study, Gene expression study
- Where
- 2 sites in United States
- Sponsor
- Sherif S. Farag
Healthy Term Infants
Evaluation of the Nutritional Value of a New Hydrolysed Rice Protein-based Formula
The goal of this interventional clinical trial is to compare the growth parameters of healthy term infants fed either a new experimental rice hydrolyzed rice protein-based formula or a control formula (standard cow's milk…
- Trial name
- RIGA (NCT07686224)
- Testing
- Rice formula (New formula based on hydrolysed rice proteins), Control formula (Standard cow's milk proteins-based formula)
- Where
- 10 sites in France
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Health and Happiness Research Limited
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Digestive Discomfort
A Study on the Effects of A2 Milk on Gut Beneficial Bacteria Growth and Digestion Improvement
The aim of this study is to evaluate the effects of A2 milk on gut beneficial bacteria growth, antioxidant activity , digestion, and inflammation improvement
- Trial name
- NCT06870097
- Testing
- A2 Milk, A1/A2 Milk
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Hepatitis A Virus
Concomitant Use of Hepatitis A Vaccine, Inactivated With Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate) and Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed Given to Healthy Children 15 Months of Age (V251-068)
This two-stage study evaluates the immunogenicity, safety, and tolerability of the administration of VAQTA™ (Hepatitis A Vaccine, Inactivated) concomitantly with PedvaxHIB™ (Haemophilus B Conjugate Vaccine [Meningococcal Protein…
- Trial name
- NCT00289913
- Testing
- Comparator: VAQTA™, Comparator: Infanrix™, Comparator: PedvaxHIB™
- Volunteers
- 1,274 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Gastric Cancer (Diagnosis)
Screening and Validation of Serum Protein Biomarkers for Early Diagnosis of Gastric Cancer
This study focuses on the discovery of protein biomarkers for the early diagnosis of gastric cancer and the development of corresponding detection methods.
- Trial name
- NCT07096752
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Digestion Chambers, Stability and Metabolism of Carotenoids and Vitamin E
Lycopene and Beta-carotene Metabolism in the Digestive Tract of Healthy Men
Consumption of foods containing carotenoids, as well as vitamin E, have been associated with lower risk of developing a number of chronic diseases.
- Trial name
- CarotenoiDig (NCT03492593)
- Testing
- lycopene, beta-carotene, control
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Stroke, Hypoalbuminemia
Brief Title: The Role of Nutrition in the Rehabilitation of Patients With Eating Disorders After a Vascular Stroke.
Brief Summary: The main objective of this thesis is to investigate the role of nutrition - specifically the administration of protein supplements (single dose and double dose) - in the rehabilitation of stroke patients with low…
- Conditions
- Stroke, Hypoalbuminemia, Sarcopenia, Osteopenia
- Trial name
- Nutristroke (NCT06961825)
- Testing
- Dietary Supplement
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Ioannina