Clinical trials: Pseudoarthrosis
Open Fracture, Pseudarthrosis
Septic Management and Outcome of Open Fracture
The aim is the study of the management and outcome of the open fractures. Some open fractures will become pseudarthrosis. Thoses pseudarthrosis may be septic or not.
- Conditions
- Open Fracture, Pseudarthrosis, Bone and Joint Infection
- Trial name
- NCT04418882
- Testing
- management and follow up of all open fractures
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Hospices Civils de Lyon
Pseudarthrosis
Two-stage Treatment of Large Bone Defects With Cerament® G and Cerament® V Plus Auto and/or Allograft Using the Masquelet Technique as Salvage Therapy After Bone Resection in Patients With Septic Pseudarthrosis
Septic pseudarthrosis of long bones are complications that can unfortunately occur after the consolidation of a fracture and some situations present risks of superinfection, persistent infection or mechanical failure (30-40% risk…
- Trial name
- EVIDENCE (NCT03970941)
- Testing
- Cost evaluation, Questionnaire
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Hospices Civils de Lyon
Trauma, Tumor
Patient Outcomes Evaluation of the EBI Vuelock™ Anterior Cervical Plate System
To prospectively collect radiographic and outcome data on patients who are having cervical spine fusion surgery with the VueLock™ Anterior Cervical Plate System
- Conditions
- Trauma, Tumor, Pseudarthrosis, Scoliosis
- Trial name
- VueLock (NCT00726128)
- Testing
- VueLock™ Anterior Cervical Plate
- Where
- 4 sites in United States
- Volunteers
- 371 people
- Sponsor
- Zimmer Biomet
TIBIA PSEUDOARTHROSES
Segment Transport Versus Acute Shortening In The Treatment of Tibial Pseudarthroses With Bone Loss
In this study the investigators are presenting the advantages as well as the disadvantages of ACUTE SHORTENING AND RELENGTHENINIG VS SEGMENT TRANSPORT methods.
- Trial name
- NCT01246934
- Testing
- ASR METHOD
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Bezmialem Vakif University
Spinal Fusion, Lumbar Fusion
Lumbar Fusion With Porous Versus Non-Porous Cages
The objective of this single site, randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo lumbar interbody fusion procedures (TLIF), supplemented with pedicle screw…
- Conditions
- Spinal Fusion, Lumbar Fusion, Arthrodesis, Spondylolisthesis
- Trial name
- NCT05583864
- Testing
- CONDUIT Porous Titanium Spinal Cage, PROTI 360 Titanium-Coated PEEK Spinal Cage
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Francis Farhadi
Pseudoarthrosis
Clinical Trial Based on the Use of Mononuclear Cells From Autologous Bone Marrow in Patients With Pseudoarthrosis
The purpose of this clinical trial is to check the non-inferiority and lower morbidity of the use of bone marrow mononuclear cells seeded onto a porous matrix of calcium phosphate, for the consolidation of tibial bone defects…
- Trial name
- NCT01813188
- Testing
- ABM seeded onto a porous TCP and DBM, autologous bone graft
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Pseudarthrosis, Ununited Fracture
Tuebingen Register of Union Failure After Fractures of the Upper and Lower Extremities
TRUFFLE is a register of clinical patient data of failed bone healing and bone non-union after fracture. All patients suffering from a long bone delayed or non-union after fracture and undergoing revision surgery are registered…
- Trial name
- TRUFFLE (NCT06098157)
- Where
- Germany
- Volunteers
- 850 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Pseudoarthrosis of Bone
SPECT/CT Bone Scan Quantification Surgery
The hypothesis of our study is that SPECT/CT bone scan fixation quantified by SUVMAX on a CZT solid state camera preoperatively would identify good responders to lumbar arthrodesis surgery.
- Trial name
- PERQUAL (NCT05183542)
- Testing
- Bone scan
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Central Hospital, Nancy, France
Nonunion of Fracture [Pseudarthrosis], Site Unspecified
Validation of Laboratory Test for Predicting Bone Tissue Regeneration
The aim of the study is to determine whether the evaluation of pro-osteogenic activity of autologous serum may predict the effectiveness of platelet gel in regenerating bone tissue in patients with nonunions of long bones.
- Trial name
- Rebone-test (NCT01362413)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Pseudoarthrosis of Bone, Pseudarthrosis
Treatment of Nonunion Fractures With Mesenchymal Stromal Cells (MSCs)
The goal of this study is to evaluate the bone regeneration capacity of BM-MSC (Bone marrow mesenchymal stromal cells), in patients with nonunion.
- Conditions
- Pseudoarthrosis of Bone, Pseudarthrosis, Non Union Fracture, Nonunion Bone Fracture
- Trial name
- MSC (NCT06103396)
- Testing
- Transplantation of autologous MSCs in nonunion fracture, Transplantation of allogeneic MSCs in nonunion fracture
- Where
- Venezuela
- Volunteers
- 30 people
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Congenital Pseudarthrosis of Tibia
A Study to Assess How Effective and Safe NVD003 is for Treating Patients With Congenital Pseudarthrosis of the Tibia.
The purpose of this study is to assess the efficacy and safety of NVD003 in pediatric participants with unilateral Congenital Pseudarthrosis of the Tibia (CPT) compared with iliac crest bone graft (ICBG) at 12 months post graft…
- Trial name
- NCT07112443
- Testing
- NVD003, Iliac Crest Bone Graft
- Where
- 7 sites in United States, Belgium and 2 more
- Volunteers
- 12 people
- Sponsor
- Novadip Biosciences
Humerus Fracture
Surgical Treamtment of Pseudarthrosis of the Humerus (Study of a Series of 53 Cases)
Pseudarthrosis of the humerus is a serious complication of humerus fractures, of particular interest to subjects young working people with pseudoarthrogenic risk factors (tobacco++).
- Trial name
- NCT06360848
- Testing
- surgery
- Volunteers
- 53 people
- Sponsor
- Ibn Jazzar Hospital
Congenital Pseudarthrosis of Tibia
NVD-003 in the Treatment of Congenital Pseudarthrosis of the Tibia
A single arm, multi-country, multi-center study in pediatric patients, suffering from congenital pseudarthrosis of the tibia (CPT), treated during the primary surgical intervention with NVD-003, an autologous 3D scaffold free…
- Trial name
- NCT05693558
- Testing
- NVD-003, an autologous 3D scaffold free osteogenic graft
- Where
- 2 sites in United States, Belgium
- Volunteers
- 4 people
- Sponsor
- Novadip Biosciences
Spondylolisthesis
Posterior Lateral Fusion (PLF) With Dynesys
The primary purpose of this study is to track and document the clinical outcomes of patients with radicular pathology following posterior lateral fusion with the Dynesys Spinal System.
- Trial name
- NCT00791180
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Zimmer Biomet
Postoperative Complications, Surgical Site Infection
Hierarchy of Effects of Laboratory Markers and Their Interaction With Comorbidity Concerning Outcome and Personalized Treatment of Trauma Patients in Emergency Care and Rehabilitation
At least ten percent of trauma patients suffer from any sort of complication. The study aims to identify a risk factor profile to early identify trauma patients at risk.
- Conditions
- Postoperative Complications, Surgical Site Infection, Wound Infection, Non-healing Wound
- Trial name
- HELICOPTER (NCT06758427)
- Where
- Germany
- Volunteers
- 2,300 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Degenerative Disc Disease, Spondylolisthesis
PMCF Neo Pedicle Screw and Cage Systems
The objectives of this clinical observational study is to evaluate the safety and efficacy (performance) of the Neo Pedicle Screw System™ and the Neo Cage System™ interbody fusion device.
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis, Spinal Tumor
- Trial name
- NCT03956537
- Testing
- NEO Pedicle Screw System™, Neo Cage System™
- Where
- 2 sites in Germany, Spain
- Volunteers
- 150 people
- Sponsor
- Neo Medical SA
Congenital Pseudarthrosis of Tibia
The Effect of Combined Surgery in Management of Congenital Pseudarthrosis of Tibia
The study aims to evaluate the clinical result of Combined Surgery in Management of Congenital Pseudarthrosis.
- Trial name
- NCT02640040
- Testing
- llizarov external fixation device, intramedullary rod fixation, surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Hunan Children's Hospital
Pseudoarthrosis of the Clavicle
"Evaluation of Clinical and Radiographic Results of Pseudarthrosis of Clavicle Treated With Plaque and Screws"
This is an interventional study for clinical and radiographic evaluation of patients operated for pseudoarthrosis of the clavicle
- Trial name
- CLAPS (NCT04041258)
- Testing
- pseudoarthrosis of clavicle
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
NF1, Congenital Pseudarthrosis of Tibia
A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 (NF1)
The current study proposes adding BMP-2 (INFUSE), an anabolic agent, at the surgical site of TPA (tibial pseudarthrosis) repair in children with NF1, compared to a control group of patients treated surgically without BMP-2.
- Trial name
- NF107-BMP2 (NCT02718131)
- Testing
- INFUSE Bone Graft (BMP-2), Control Group
- Where
- 16 sites in United States, Australia
- Volunteers
- 5 people
- Sponsor
- University of Alabama at Birmingham
Pseudarthrosis
Observational Retrospective Study on the Clinical and Radiographic Outcomes of the Aseptic Pseudarthrosis Treatment of the Upper Limb
The aim of this study is to collect boh clinical and radiographic data coming from the treated patients for pseudarthrosis of the upper limbs from 2000 to 2017 at the SC Orthopedic Surgery, Innovative Techniques of the Istituto…
- Trial name
- NCT04200872
- Testing
- biological adjuvants, no biological adjuvants
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Istituto Ortopedico Rizzoli