Clinical trials: Psychological Disorders
Autoimmune Diseases, Mental Disorders Diagnosed in Childhood
Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)
Recent research studies of early onset-obsessive compulsive disorder (OCD) and Tourette's syndrome have questioned whether autoimmunity could play a role in the development of these conditions.
- Conditions
- Autoimmune Diseases, Mental Disorders Diagnosed in Childhood, Schizophrenia
- Trial name
- NCT00001768
- Testing
- Intravenous immunoglobulin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Mental Health (NIMH)
Virtual Reality
Virtual Realityon Pain, Anxiety and Comfort During Trigger Point Injection
To determine the effects of virtual reality application during trigger point injection on patients' pain, anxiety and comfort levels.This research was planned as a randomized controlled experimental type.
- Trial name
- NCT06140368
- Testing
- virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Izmir Bakircay University
Depression, Bipolar Disorder
Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder
Anhedonia, characterized as (a) the diminished motivation to participate in activities, and/or (b) diminished enjoyment of a pleasurable activity are common symptoms among women diagnosed with mood disorders.
- Conditions
- Depression, Bipolar Disorder, Anhedonia
- Trial name
- NCT02494050
- Testing
- Behavioral Activation-Full, Behavioral Activation-Short, Bipolar Disorder Collaborative Care
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Northwestern University
Stroke, Cardiovascular
Additional Effects of Mental Imagery Along With Task Oriented Training on Kinesiophobia in Patients With Stroke
The objective of this study to determine the effect of mental imagery and task oriented training on Kinesiophobia in stroke patients. And to determine the association of Kinesiophobia with gait and balance in stroke patients.
- Trial name
- NCT06303050
- Testing
- Mental Imagery with task Oriented training group, Task Oriented training group
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Bruxism, Sleep
Evaluation of the Effectiveness of Infrared LED Photobiomodulation in Children With Sleep Bruxism
Sleep bruxism is a masticatory muscle activity characterized as rhythmic (phasic) or non-rhythmic (tonic). The literature reports the prevalence rates, diverse etiologies and different types of treatment.
- Trial name
- NCT03710174
- Testing
- Infrared LED photobiomodulation, Occlusal splint
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Schizophrenia and Related Disorders, Bipolar Disorder
Exercise Therapy in Mental Disorders-study
The study will compare standard high-intensity training with brief high-intensity training in people with schizophrenia-spectrum or bipolar disorder.
- Trial name
- NCT06313918
- Testing
- High intensity training (HIT)
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Haukeland University Hospital
Older Adults, Anxiety
Behavioral Activation and Medication Optimization for Perioperative Mental Health Feasibility Study
Inadequate management of preoperative mental health disorders often contributes to poor postoperative outcomes, including increased rates of readmission, delirium, falls, and mortality.
- Conditions
- Older Adults, Anxiety, Depression, Cardiac Surgery
- Trial name
- NCT05110690
- Testing
- Behavioral Activation, Medication Optimization
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Washington University School of Medicine
Delirium, Nurse's Role
Delirium Prevention Guideline for Intensive Care Patients
Delirium is a complication characterized by fluctuations in orientation, memory, thinking, or behavior, with sudden onset of these changes.
- Trial name
- NCT06403410
- Testing
- Delirium Prevention Guideline
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Istanbul Demiroglu Bilim University
Confusion, Inflammation
Confusion in the Elderly After Colon Surgery
A study will be conducted to determine if there is any cognitive benefit in elderly patients having open versus minimally invasive colon cancer surgery.
- Conditions
- Confusion, Inflammation, Acute Phase Reaction, Surgery
- Trial name
- NCT01623297
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- New York Hospital Queens
Sleep Disorder
Sleep Disorders and Quality of Life in Patients With Multiple Sclerosis
1. To determine sleep disturbance in different types of multiple sclerosis. 2. To asses the effect of sleep disturbance on quality of life in patients with multiple sclerosis. 3.
- Trial name
- NCT06012513
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hypertension, Self-management
The Effect of a Disease Self-management Program Through a Mobile Applications for Patients With Hypertension
Hypertension is a major cause of death worldwide. Patients should adjust their lifestyle and learn how to maintain a balance between self-management of a disease and their daily livelihood.
- Conditions
- Hypertension, Self-management, Mobile Applications
- Trial name
- NCT05263726
- Testing
- DSMP through a Mobile Applications
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Autism Spectrum Disorder, Executive Dysfunction
Non-invasive Brain Stimulation in Children With Autism
Although many children diagnosed with autism spectrum disorder (ASD) make significant progress in learning and their cognitive skills improve with applied behavior analysis (ABA), there are a significant number of children who…
- Conditions
- Autism Spectrum Disorder, Executive Dysfunction, Child Autism
- Trial name
- NCT05105126
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
ASD, Child Behavior Problem
Autism and Disruptive Behavior Trial
Investigators seek to transform the delivery of health care to children with autism spectrum disorder (ASD) and behavioral health problems (and their families) by developing an innovative tiered set of interventions.
- Trial name
- NCT04204226
- Testing
- Social Worker, Autism Behavioral Health Navigation (ABHN), Social work + ABHN
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital of Philadelphia
Anxiety, Adolescent Development
Adverse Adolescent Pathways to Substance Use
Purpose: This 5-year R01 study will elucidate the role of maturational change across adolescence in neural connectivity and physiological stress responses in the relationship between anxiety and adverse pathways to substance use…
- Conditions
- Anxiety, Adolescent Development, Substance Use
- Trial name
- APSU (NCT06977178)
- Testing
- Trier Social Stress Test
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ovariectomy, Hysterectomy
Surveillance Study of Women Taking Intrinsa®
The primary objective of the study is to assess the risks of testosterone transdermal patch use in a representative study population. The primary clinical outcome of interest is breast cancer.
- Conditions
- Ovariectomy, Hysterectomy, Hypoactive Sexual Desire Disorder
- Trial name
- EMPOWER (NCT00551785)
- Where
- Germany
- Volunteers
- 328 people
- Sponsor
- Center for Epidemiology and Health Research, Germany
Anxiety
Premedication With Melatonin and Alprazolam Combination Versus Alprazolam or Melatonin Alone
Background: Benzodiazepine, a common premedicant, suppresses endogenous melatonin levels and thus paradoxically increases episodes of arousal during sleep and thus causes restlessness and hangs over effects.
- Trial name
- NCT01486615
- Testing
- meloset (melatonin), stresnil ( melatonin and alprazolam), (alprax) alprazolam
- Where
- 2 sites in Nepal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Alcohol Use Disorder
Human Laboratory Study of Varenicline for Alcohol Use Disorder
This study is a double-blind, randomized, placebo-controlled, parallel group, two-site study designed to assess the effects of varenicline as compared with placebo on responses to in vivo alcohol cue exposure in the human…
- Trial name
- NCT03035708
- Testing
- Varenicline
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Fatigue, Sleep Deprivation
Effect and Utilization of Protected Time Among Interns on Extended Duty-Hour Call Shifts
This study will test the feasibility and effectiveness of protected time for physicians in training during 30 hour shifts in a medical intensive care unit. The primary outcome will be fatigue.
- Conditions
- Fatigue, Sleep Deprivation, Depression
- Trial name
- NCT00983008
- Testing
- Protected time and Dedicated time
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Providence Health & Services
Alcohol Dependence
Treatment for Alcohol Dependence With Gabapentin
Alcohol use disorders are present across medical specialties, with alcohol-related deaths particularly prevalent in the categories of injury, liver cirrhosis, cancer, cardiovascular disease, disorders of the peripheral nerves and…
- Trial name
- TAG (NCT02771925)
- Testing
- Gabapentin 2g/day divided in two doses for 24 weeks
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dayanand Medical College and Hospital
Alzheimer Disease (AD)
The Co-Production and Evaluation of the Computerised Cognitive Assessment for Preclinical Alzheimer's Disease (CoCoA-PAD)
Background. Healthcare professionals can now diagnose the earliest stages of Alzheimer's disease (early-AD) and new drugs are effective at slowing the disease.
- Trial name
- CoCoA-PAD (NCT07598617)
- Where
- 3 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Plymouth
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