Clinical trials: Psychopathology
Psychopathology
Virtual Mom Power With High-Adversity Mothers and Children (MPHAMC)
This study is a randomized controlled confirmatory efficacy trial of virtual Mom Power (MP), a group-based, relationship-focused multifamily preventive intervention.
- Trial name
- NCT05129397
- Testing
- Mom Power, Mom Power Informational Mailing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tulane University
General Psychopathology, Fatigue
An Energetic View on Creativity, Psychopathology and Intelligence: The Brain2Business Study
The interventional part of the study aims to assess the acute effect of the Brain2Business (B2B) tool on creative thinking (primary objective) in adults with psychological disorders.
- Conditions
- General Psychopathology, Fatigue, Depressive Disorder, Major
- Trial name
- B2B (NCT05544877)
- Testing
- Integrated 5-day Gratitude Exercise and Behavioral Activation Program
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Psychiatrische Dienste Thurgau
Psychopathology
External Validation by Machine Learning and Reduction of the Input Dimensions of the D-PSY Scale for Dimensional Psychopathology
There have been debates about whether psychiatric disorders should be classified according to categories (categorical model) or according to a continuum between normal and pathological functioning (dimensional model).
- Trial name
- D-Psy adultes (NCT05675215)
- Testing
- Psychopathology screening tests
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Institut pour la Pratique et l'Innovation en PSYchologie appliquée (Institut Pi-Psy)
Psychopathology
Can Applying the Science of Habit Formation to Contemplative Practice Improve Outcomes
In the present study, the investigators will conduct a confirmatory efficacy trial to test whether improving practice automaticity (i.e., habit formation) of self-compassionate touch improves outcomes in the predicted direction.
- Trial name
- NCT05866718
- Testing
- Self-Compassionate Touch Intervention, Habit Formation Tools
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Adolescent, Psychopathology
An Evidence-based Family Support Program for Parents and Children in Palestine: A Theory-based Intervention
Few evidence-based programs exist to support children and families affected by sociopolitical conflict, despite documented evidence of their heightened risk for emotional and behavioral adjustment problems associated with…
- Conditions
- Adolescent, Psychopathology, Parent-Child Relations, Violence
- Trial name
- NCT05706376
- Testing
- Promoting Positive Family Futures, Treatment as Usual
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Bipolar Disorder, Involutional Depression
Study of the Psychological Development of Children of Parents With and Without Affective Disorders
This research study is the continuation of a study started more than 20 years ago. The study was designed to explore the effect that depressed parents have on their children and to better understand the factors that contribute to…
- Conditions
- Bipolar Disorder, Involutional Depression, Mood Disorder
- Trial name
- NCT00001170
- Where
- United States
- Volunteers
- 1,045 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Emotional Problem, Behavior Problem
Enhancement of Emotion Regulation Skills in Adolescents
For the current study, a prevention program is developed and applied to enhance the emotion regulation skills of adolescents. Before and after the application of the prevention program, all participants will be assessed for their…
- Trial name
- NCT04001140
- Testing
- Enhancement of emotion regulation skills
- Where
- Cyprus
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Transdiagnostic Psychopathology
Single Session Intervention for Building Self-Compassion Habits-RCT
The study will test a single session self-compassion intervention that leverages an ultra-brief contemplative exercise. It will evaluate the effect of this intervention on psychopathology, stress, growth mindset, positive affect…
- Trial name
- NCT05199779
- Testing
- Single Session Intervention Leveraging an Ultra-Brief Self-Compassion Exercise, Finger-Tapping Active Control
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Distress, Emotional, Internalizing Mental Health Symptoms
Piloting a School-Based Distress Tolerance Skills Program for Adolescents
Research suggests that an individual's perceived ability to withstand distressing or upsetting emotions (i.e., distress tolerance; DT) is a common risk factor across several mental health conditions that commonly emerge during…
- Trial name
- STRIDE (NCT06638853)
- Testing
- Distress Tolerance Skills Training
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chromosome 22q11.2 Deletion Syndrome
Genetics and Psychopathology in the 22q11 Deletion Syndrome
The purposes of this study are to: 1. study the nature and longitudinal course of psychiatric symptoms in children with the 22q11.2 deletion syndrome and 2. identify genes that contribute to the occurrence of these symptoms.
- Trial name
- NCT00161109
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Medical Education
Add-on Video-based Training on Mental Status Examination Skills
The goal of this clinical triall is to investigate the training effect of access to authentic patient video on mental status examination performance among 5th year Danish medical students.
- Trial name
- VV-RCT (NCT05795387)
- Testing
- Video-based self-regulated training on the mental status exam, E-course with written material on the mental status exam
- Where
- 2 sites in Denmark
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Personality Disorder
An Evolutionarily Informed Conceptualization of Personality Pathology
The purpose of this study is to explore the reliability of a new evolutionarily-informed model for conceptualizing personality pathology.
- Trial name
- EIC-PP (NCT06623838)
- Testing
- Evolutionarily informed case conceptualization
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tages Onlus
Rejection Sensitivity, Puberty
Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls
This longitudinal study is designed to test bidirectional relationships between preteen girls' mental health and social media experiences.
- Conditions
- Rejection Sensitivity, Puberty, Psychopathology
- Trial name
- NCT06777823
- Testing
- Social Rejection Task
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Mental Health Issue, Adverse Childhood Experience
Chinese Community Sample of Hierarchical Model of Psychopathology
By validating Hierarchy Model of psychopathology(HiTOP) in Chinese community samples, this study aims for illumating the problem of diagnostic heterogeneity and high comorbidity within existing psychiatric classification systems…
- Trial name
- NCT06105970
- Testing
- No intervention
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Anxiety Symptoms, Depressive Symptoms
Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
The goal of the project is to test whether a single-session intervention teaching incremental theories of personality, or the belief that one's personality is malleable, can strengthen recovery from social stress and reduce the…
- Trial name
- NCT03132298
- Testing
- Implicit Theories of Personality Program, Control Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Harvard University
Scoliosis
HRQoL and Function of Adults Treated in Adolescence for Scoliosis With Physical Exercises
We attempt to investigate the influence of physiotherapy and physical activity education applied in adolescence on physical fitness, curve progression, pulmonary function, physical activity and quality of life in adulthood.
- Trial name
- NCT01384955
- Where
- Poland
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Anorexia Nervosa, Bulimia Nervosa
PROspective Longitudinal All-comer Inclusion Study in Eating Disorders
The PROLED study is a prospective and longitudinal study of patients with Eating Disorders. Annual interviews and collection of biological samples are done, as well as during changes in disease course e.g. during hospitalization.
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, Eating Disorder NOS
- Trial name
- PROLED (NCT03224091)
- Where
- Denmark
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Developmental Psychological Disorder
Developmental Psychopathology and the Gene-environment Interaction
The present is a followup study that aims at investigating the effect of genetic and environmental factors on the possible development of psychopathological conditions in a longitudinal perspective.
- Trial name
- TwinAger (NCT04489069)
- Testing
- MRI, Clinical and Neuropsychological evaluations, Drawing DNA sample
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Intergenerational Relations
Maternal Psychopathology and Offspring Mental Health (PSI_PER)
Pregnant women consecutively referred to the Perinatal Psychiatric Outpatient Department, those in charge of the Psychiatric Outpatient Department and pregnant healthy controls from the general population will be recruited on a…
- Trial name
- PSI_PER (NCT03897816)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Loneliness, Worry, Rumination, Health Anxiety, Depression, Anxiety
Loneliness During the NPIs for the COVID-19 Pandemic in Norway: Risk Factors and Associations With Psychopathology
The present study of loneliness during the COVID-19-related NPIs is part of a larger project aiming to investigate psychological reactions and symptoms associated with the current and ongoing governmental initiatives in place in…
- Trial name
- NCT04365881
- Testing
- Cross-sectional observational study
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- Modum Bad