Clinical trials: Pterygium
Pterygium, Dry Eye
Using Impression Cytology to Observe the Cytological Changes of Ocular Surface Cells in Various Ocular Surface Disorders
Currently, due to the advantage of noninvasive, localized, rapid, painless and easily repeatable of impression specimens, the technique is an ideal method of investigating ocular surface disorders when the diagnosis is not…
- Conditions
- Pterygium, Dry Eye, Tumor
- Trial name
- NCT01387971
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dry Eye
Tear Layer Lipid Thickness in Pterygium Patient Before and After Surgery
The investigators study aims to capture the objective effects of pterygium surgery on tear layer lipid thickness and the tear layer.
- Trial name
- NCT02160769
- Where
- Singapore
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Pterygium of Both Eyes
Comparative Study of Muc5ac and Muc2 Mucins in Tear Film Concentration in Surgical Treated Pterygia Patients
To identify and compare the differences in the concentration of the Muc2 and Muc5AC mucins in tear film in patients who underwent pterygium surgery using amniotic membrane transplantation and conjunctival autograft surgery.
- Trial name
- NCT04385446
- Testing
- Amniotic membrane transplantation
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Pterygium, Primary
Conjunctival Autologous Transplantation Using Fibrin Glue in Primary Pterygia
To evaluate the recurrence and postoperative complications rates after conjunctival autograft surgery using fibrin adhesive for primary pterygium
- Trial name
- NCT00949728
- Testing
- Conjunctival autograft using fibrin glue
- Where
- Brazil
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Hospital de Olhos Sadalla Amin Ghanem
Human Papilloma Virus Infection, Pterygium
Prevalence of HPV-associated Eye Infection and Cytokine Levels in Tears From Patients Diagnosed With Pterygium
Prevalence of HPV-associated eye infection and cytokine levels in tears from patients diagnosed with pterygium
- Trial name
- NCT04117386
- Testing
- HPV genotyping assay using HPV GenoArray Diagnostic Kits (Hybribio Ltd., Sheung Wan, Hong Kong), Bio-Plex® 200 system (Bio- Rad, Hercules, CA)
- Where
- Thailand
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Pterygium, Ocular Surface Disease
Autologous ex Vivo Conjunctival Epithelial Cell Expansion for Ocular Surface Transplantation
To evaluate the use of cultivated conjunctival epithelial equivalents for the treatment of ocular diseases
- Conditions
- Pterygium, Ocular Surface Disease, Stevens Johnson Syndrome, Chemical Injury
- Trial name
- NCT00346450
- Testing
- Cultivated conjunctival transplantation
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Pterygium, Bevacizumab
Topical Bevacizumab for Preventing Recurrent Pterygium
The purpose of this study is to determine whether bevacizumab eye drop is effective in the treatment of recurrent pterygium.
- Conditions
- Pterygium, Bevacizumab, VEGF, Anti-VEGF
- Trial name
- NCT01311960
- Testing
- bevacizumab eye drop 0.05%, normal saline 0.9%
- Where
- Thailand
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Pterygium
Efficacy and Safety of Sub-tenon Ranibizumab for Recurrent Pterygia
Ranibizumab, an effective antineovascular drug, will be studied for safety and efficacy in pterygium, a neovascular disorder of the ocular surface.
- Trial name
- NCT01169909
- Testing
- Ranibizumab
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Pterygium
Safety Study of Avastin Used as Adjunctive Therapy in Pterygium Surgery
This study will evaluate the efficacy and safety of the use of bevacizumab (Avastin) as an adjunctive medication during pterygium surgery in preventing pterygium recurrence.
- Trial name
- NCT01115517
- Testing
- Bevacizumab, Mitomycin C
- Where
- 2 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pterygium
Comparison of Glue With Sutures for Pterygium Surgery
Pterygium excision surgery involves excising the abnormal growth from the cornea and filling the defect with a conjunctival (white of the eye) graft from the superior part of the eye.
- Trial name
- NCT00326560
- Testing
- Pterygium excision and conjunctival autograft
- Where
- New Zealand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wellington Hospital
Pterygium, Subconjunctival Hemorrhage
Brimonidine Tartrate for Pterygium Surgery
Pterygium excision and conjunctival autograft surgery is commonly done to treat pterygiums. Excessive bleeding during the procedure creates a challenging operating field, prolongs surgery time, and prolongs healing.
- Trial name
- NCT04683159
- Testing
- Brimonidine Tartrate 0.15% Oph Soln, Brimonidine Tartrate 0.025% Oph Soln
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists
Pterygium of the Conjunctiva and Cornea
Randomized Controlled Trial of Subconjunctival Bevacizumab Injection in Impending Recurrent Pterygium
Hypothesis: Subconjunctival bevacizumab injection may potentially suppress neovascularization in pterygium, preventing or retarding the progression of recurrence.
- Trial name
- NCT01288404
- Testing
- Fluorometholone, Bevacizumab
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Pterygium
ICG Angiography in Amniotic Membrane Graft and Conjunctival Autograft After Pterygium Excision
To evaluate graft vascularization and compare the vascularization patterns of conjunctival autografts with amniotic membrane grafts to better understand the factors involved in pterygium recurrence.
- Trial name
- NCT00383825
- Testing
- Anterior segment indocyanine green angiography
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baskent University
Pterygium
Determinants of Pterygium Occurrence and Recurrence in a Rural African Population
The aim of the study is to find out why pterygium occurs and recurs in a rural African population. Participants will be interviewed on personal and lifestyle information, family history of pterygium, environmental exposure and…
- Trial name
- NCT00713180
- Testing
- Pterygium excision followed by grafting
- Where
- South Africa
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Anguria, Peter, M.D.
Hearing Impairment
Epidemiology of Non-syndromic Dominant Deafness
Hearing impairment is a common disorder that affects at least 7% of individuals in our countries. Even the causes of hearing impairment are numerous, genetic causes represent the main factor of sensorineural deafness.
- Trial name
- SURDOM (NCT01150305)
- Testing
- blood sample
- Where
- France
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Primary Pterygium
Comparison of Compressed Continuous Suture and Conventional Suture in Pterygium Surgery
To compare the advantages and disadvantages of continuous suture with suture and conventional Suture in primary pterygium surgery for autologous conjunctival graft fixation
- Trial name
- NCT07244276
- Testing
- Compression continuous suture with suture crimping, Conventional Suture with suture crimping
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Recurrent Pterygium of Eye, Steroid-Induced Glaucoma
Topical 0.2% Loteprednol Etabonate vs. Topical 0.1% Dexamethasone in Impending Recurrent Pterygium
The objective of this study was to evaluate the efficacy of topical 0.2% loteprednol etabonate, a 'soft steroid', compared with topical 0.1% dexamethasone, which is widely used in postoperative pterygium excision to prevent the…
- Trial name
- NCT04075227
- Testing
- 0.2% loteprednol etabonate, 0.1% dexamethasone
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Wannisa Suphachearabhan
Pterygium
Pterygium Head Body MMC1: Two Different Surgical Procedures and Their Effect on Endothelial Cell Count.
To evaluate changes in endothelial cell count after pterygium surgery with mitomycin C (MMC) 0.02%
- Trial name
- PHB-MMC1 (NCT02641132)
- Testing
- Mitomycin C 0.02%, Pterygium surgery
- Where
- 2 sites in Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Recurrent Pterygia
Amniotic Membrane Associated With Conjunctival Autograft Versus Conjunctival Autograft for Recurrent Pterygia
The purpose of this study is to compare amniotic membrane associated with conjunctival autograft versus conjunctival autograft alone in the treatment of recurrent pterygia.
- Trial name
- NCT00802620
- Testing
- Conjunctival autograft versus conjunctival autograft treatment for recurrent pterygia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Pterygium of Conjunctiva and Cornea
Recurrence Rate of Mini-SLET vs. Limbal-Conjunctival Autograft in Primary Pterygium Excision
To study the efficacy and safety of amniotic membrane transplantation as an adjunctive therapy after surgical excision of primary pterygium and compare the clinical outcomes with conjunctival autograft
- Trial name
- NCT03363282
- Testing
- Pterygium Excision
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana