Clinical trials: Pulmonary Metastasectomy
Colorectal Adenocarcinoma, Colorectal Carcinoma Metastatic in the Lung
Chemotherapy and/or Metastasectomy in Treating Patients With Metastatic Colorectal Adenocarcinoma With Lung Metastases
This phase II trial studies how well chemotherapy and/or metastasectomy work in treating patients with colorectal adenocarcinoma that has spread to the lungs (metastases).
- Conditions
- Colorectal Adenocarcinoma, Colorectal Carcinoma Metastatic in the Lung, Stage IV Colorectal Cancer AJCC v8, Stage IVA Colorectal Cancer AJCC v8
- Trial name
- NCT03599752
- Testing
- Chemotherapy, Metastasectomy
- Where
- 6 sites in United States, Canada
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Metastases, Colorectal Cancer Metastatic
Colorectal Pulmonary Metastases: Pulmonary Metastasectomy Versus Stereotactic Ablative Radiotherapy
COPPER is an international, multicenter, parallel-arm, phase III randomized controlled trial comparing two local treatment strategies (SABR or metastasectomy) for patients with an indication for local treatment for limited (max.
- Trial name
- COPPER (NCT05808790)
- Testing
- Minimally invasive pulmonary metastasectomy, Stereotactic ablative radiotherapy
- Where
- Netherlands
- Volunteers
- 394 people
- Sponsor
- Amsterdam UMC, location VUmc
Primary Solid Tumors
Robotic Surgery in Pulmonary Metastasectomy
The study is observational, multicenter retrospective and will involve multiple research centers. The aim is to outline the indications for surgical management with robot-assisted pulmonary metastasectomy through a confrontation…
- Trial name
- ROME (NCT06466070)
- Where
- 3 sites in Italy
- Volunteers
- 1,650 people
- Sponsor
- Scientific Institute San Raffaele
Stage IV Colorectal Cancer, Liver Metastases
Detection of CTCs in Patients Undergoing Surgery for Stage IV Colorectal Cancer
Colorectal cancer (CRC) is the second leading cause of cancer deaths in the United States. About 90% of CRC related deaths are due to metastatic spread-mostly to the liver and lungs.
- Conditions
- Stage IV Colorectal Cancer, Liver Metastases, Lung Metastases
- Trial name
- NCT01722903
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Milton S. Hershey Medical Center
Osteosarcoma, Pulmonary Metastasis
Safety and Feasibility of Intraoperative Visualization With Cytalux in Children
Pediatric subjects aged 6-17 with biopsy confirmed cancer and imaging findings suspicious for pulmonary metastatic disease scheduled to undergo pulmonary metastasectomy via and open or minimally invasive approach.
- Conditions
- Osteosarcoma, Pulmonary Metastasis, Fluorescence, Metastatic Sarcoma
- Trial name
- Cytalux (NCT06235125)
- Testing
- Cytalux
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Endometrial Cancer, Kidney Cancer
Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Conditions
- Endometrial Cancer, Kidney Cancer, Metastatic Cancer, Ovarian Cancer
- Trial name
- NCT00002764
- Testing
- filgrastim, doxorubicin hydrochloride, ifosfamide
- Where
- Sweden
- Volunteers
- 340 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Lung Metastasis, Colorectal Cancer
Radiofrequency Ablation in Resectable Colorectal Lung Metastasis
Lung metastasectomy is the only therapeutic option to provide a long-survival in patients with colorectal lung metastases. Recent studies have shown that radiofrequency (RF) ablation is a safe and useful therapeutic option for…
- Trial name
- NCT00776399
- Testing
- Lung radiofrequency ablation
- Where
- 16 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Mie University
Lung Neoplasms, Neoplasm Metastasis
Mediastinal Lymph Node Dissection in Conjunction With Pulmonary Metastasectomy From Colorectal Cancer
To study whether or not total mediastinal lymph node dissection in conjunction with pulmonary metastasectomy from colorectal cancer is associated with improved survival compared to pulmonary metastasectomy only.
- Conditions
- Lung Neoplasms, Neoplasm Metastasis, Colorectal Cancer
- Trial name
- NCT03113318
- Testing
- Total mediastinal lymph node dissection and pulmonary metastasectomy, Only pulmonary metastasectomy
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Colorectal Cancer, Pulmonary Metastases
A Randomised Trial of Pulmonary Metastasectomy in Colorectal Cancer
Patients who have been treated successfully for bowel cancer (colorectal cancer) sometimes go on to develop nodules of disease in another part of the body.
- Trial name
- PulMiCC (NCT01106261)
- Testing
- Metastasectomy, Active monitoring
- Where
- 24 sites in China, Italy and 2 more
- Volunteers
- 93 people
- Sponsor
- University College, London
Osteosarcoma
Pulmonary Resectable Osteosarcoma Treated by Metastasectomy and Pre-operative Immunotherapy and Stereotactic Body Radiotherapy (PROMIS): a Prospective Clinical Trial
The aim of this study is to evaluate the efficacy and safety of pre-operative concurrent Stereotactic Body Radiotherapy (SBRT) and and programmed cell death protein-1 (PD-1) blockade immunotherapy followed by surgical…
- Trial name
- PROMIS (NCT06114225)
- Testing
- metastasectomy and pre-operative immunotherapy (gemcitabine and penpulimab ) and stereotactic body radiotherapy
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Ruijin Hospital
Pulmonary Metastases
Use of Thoracoscopic Intraoperative Lung Ultrasound to Identify Pulmonary Metastases in Patients Submitted to Pulmonary Metastasectomy With Radical Intent.
Experience drawn from many scientific articles showed that many patients who develop a limited pattern of pulmonary metastases after treatment of a primary tumor may benefit from surgical resection of the lung deposits.
- Trial name
- VATS-US1 (NCT03864874)
- Testing
- Intraoperative intracavitary lung ultrasonography
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Neoplasm Metastasis, Sarcoma
Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy
Background: Most patients who have surgery for cancer that has metastasized (spread) to the lungs later get more metastases that cannot be treated with surgery or chemotherapy.
- Conditions
- Neoplasm Metastasis, Sarcoma, Neoplasms, Germ Cell and Embryonal, Melanoma
- Trial name
- NCT02839694
- Testing
- decitabine (DAC), Tetrahydrouridine (THU), Celecoxib
- Sponsor
- National Cancer Institute (NCI)
Surgical Resection, Stereotactic Body Radiotherapy
Post SBRT Pulmonary Metastasectomy (PSPM) Trial
The goal of this study is to determine the effectiveness of SBRT on reducing tumor viability at a pathologic level and also to evaluate the effects of combined modality treatment on low volume pulmonary metastases, in hopes of…
- Conditions
- Surgical Resection, Stereotactic Body Radiotherapy, Lung Cancer, Pulmonary Metastasectomy
- Trial name
- PSPM (NCT04160143)
- Testing
- Surgical resection and stereotactic body radiation therapy (SBRT)
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- McMaster University