Clinical trials: Quadriceps Muscle Function, open to volunteers
Emphysema
Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment
Rationale: Chronic obstructive pulmonary disease (COPD) is characterised by a high prevalence of peripheral muscle dysfunction, which can have significant clinical consequences, including decreased exercise capacity, reduced…
- Trial name
- ENDURANCE (NCT06025500)
- Testing
- 31P-Magnetic Resonance Spectroscopy (31P-MRS)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
Anterior Cruciate Ligament Injury
Neuromuscular Profiles After Anterior Cruciate Ligament Reconstruction
The NEURO-ACL-ISOEMG study is an observational, cross-sectional, exploratory study conducted in patients between 4 and 12 months after anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NEURO-ACL-ISOE (NCT07792863)
- Testing
- Neuromuscular and Patient-Reported Assessmen
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hopitaux de Saint-Maurice
Anterior Cruciate Ligament Reconstruction Rehabilitation, Quadriceps Muscle Function
Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction
After knee surgery for a torn ACL, many women struggle with weak thigh muscles for years, partly due to reduced brain signals to these muscles.
- Trial name
- NCT07128602
- Testing
- active transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Arcadia University
Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries
Correlation Between Psychological Readiness, Knee Function, and Isokinetic Performance After Anterior Cruciate Ligament Reconstruction (ACLR) Using Peroneus Longus Tendon Graft (PL-ACL-2025)
This clinical trial aims to investigate the correlation between psychological readiness, knee function, and isokinetic performance after anterior cruciate ligament reconstruction (ACLR) using the Peroneus Longus tendon graft…
- Conditions
- Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries, Knee Injuries
- Trial name
- PL-ACLR (NCT07201597)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Healthy Volunteers, Neuromuscular Function
Eco-guided Neuromodulation of the Femoral Nerve on the Performance of Amateur Athletes.
This randomized crossover study aims to evaluate whether different percutaneous electrical nerve stimulation (PENS) protocols produce changes in neuromuscular performance in healthy adults.
- Trial name
- NCT07719179
- Testing
- Theta Burst Protocol, 10-10-10 Protocol, 5-55 Protocol
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Osteoarthritis (OA) of the Knee
The Effects of Functional Electrical Stimulation (FES) and Exercise on the Quadriceps in Patients With Knee Osteoarthritis
In our study, we aimed to compare the effects of functional electrical stimulation (FES) and an exercise program on quadriceps muscle strength and structural characteristics, as well as their impact on gait analysis, pain…
- Trial name
- NCT07309003
- Testing
- functional electrical stimulation (FES)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ankara City Hospital Bilkent
ACL - Anterior Cruciate Ligament Rupture
Optimizing Graft Selection for ACL Reconstruction
Purpose: To investigate the differences between the three most common methods for reconstruction of the anterior cruciate ligament (ACL), to support the development of the best method for the individual patient.
- Trial name
- GRASE-ACL (NCT05342441)
- Testing
- QT graft, ST/Gr graft, BPTB graft
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Hvidovre University Hospital
Quadriceps Atrophy, ACL Reconstruction
Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?
The purpose of this study is to evaluate the effectiveness of physical therapy (PT) plus BFR training compared to PT alone (without BFR training) after ACL reconstruction in patients who require extended limited weight bearing…
- Trial name
- NCT03096366
- Testing
- Blood flow restriction, Physical therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center, Houston
Knee Osteoarthristis, Knee Pain Arthritis
Stimulation of Peripheral Afferents to Reduce Muscle Inhibition at the Knee
Knee osteoarthritis is a leading cause of disability, and the muscle weakness that limits walking in this population arises not only from the joint itself but from afferent signals that inhibit motor drive to the thigh muscle…
- Conditions
- Knee Osteoarthristis, Knee Pain Arthritis, Knee Pain Chronic
- Trial name
- SPARK (NCT07832669)
- Testing
- Peripheral Electrical Stimulation (PES), Paired Pulse Electrical Stimulation (ppES)
- Volunteers
- 50 people
- Sponsor
- Northeastern University
Knee Osteoarthritis
Clinical Importance of Occult Suprapatellar Effusion in Knee Osteoarthritis
Small amounts of fluid in the knee joint may not always be visible during a standard ultrasound examination performed while the leg is relaxed.
- Trial name
- NCT07876752
- Testing
- Static and Dynamic Suprapatellar Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Mardin Artuklu University
Anterior Cruciate Ligament Injury
Effectiveness of a Digital Prehabilitation Programme Before ACL Reconstruction
Background Prehabilitation prior to anterior cruciate ligament reconstruction (ACLR) has been shown to improve preoperative knee function, enhance quadriceps strength, and optimize postoperative recovery.
- Trial name
- NCT07643480
- Testing
- Digital Prehabilitation Programme, Usual Care
- Volunteers
- 60 people
- Sponsor
- Alejandro Caña Pino
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Quadriceps Tendon vs Peroneus Longus Tendon in ACL Reconstruction
This prospective randomized clinical trial aims to compare quadriceps tendon and peroneus longus tendon autografts in anterior cruciate ligament reconstruction.
- Trial name
- NCT07671729
- Testing
- Anterior Cruciate Ligament Reconstruction Using Quadriceps Tendon Autograft, Anterior Cruciate Ligament Reconstruction Using Peroneus Longus Tendon Autograft
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Acibadem University
Total Knee Arthroplasty, Total Knee Arthroplasty Recovery
Femoral Triangle Block vs Adductor Canal Block on Early Quadriceps Function After Total Knee Arthroplasty
The goal of this clinical trial is to compare the effects of femoral triangle block (FTB) and adductor canal block (ACB) on early quadriceps function after total knee arthroplasty (TKA).
- Conditions
- Total Knee Arthroplasty, Total Knee Arthroplasty Recovery, Total Knee Arthroplasty Postoperative Pain
- Trial name
- NCT07524387
- Testing
- Femoral Triangle Block (FTB) Group, Adductor Canal Block (ACB) Group
- Where
- Japan
- Volunteers
- 136 people
- Sponsor
- Social Medical Corporation Daiyukai
Transcutaneous Electric Nerve Stimulation, Chronic Low-back Pain
High Frequency RF Current Effects on Muscle Pain and Function
The purpose of this study is to examine the acute and chronic effects of high frequency electrical current transfer (frequently called "TECAR") on pain and functional movement in individuals with a musculoskeletal injury or pain.
- Conditions
- Transcutaneous Electric Nerve Stimulation, Chronic Low-back Pain, Hamstring Injury, Muscle; Injury, Quadriceps (Thigh)
- Trial name
- NCT05345015
- Testing
- Radiofrequency Energy Transfer, Transcutaneous Nerve Stimulation
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- Aristotle University Of Thessaloniki
Intensive Care Unit Acquired Weakness, Muscle Weakness
Early Assessment of Quadriceps Muscle Recovery by Dynamometry and 3D Ultrasound in Intensive Care Patients Under Invasive Mechanical Ventilation
Patients in intensive care often develop acquired muscle weakness (ICUAW or Intensive Care Unit Acquired Weakness) due to immobilization and muscle atrophy.
- Trial name
- DYNAMOREA (NCT07069959)
- Testing
- Early assessment of quadriceps muscle strength
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Patellofemoral Pain Syndrome
Quadriceps Strengthening At Different Angles in Patellofemoral Pain
Introduction: Patellofemoral pain (PFP) is characterized by anterior, retropatellar and/or peripatellar pain during activities such as running, squatting, kneeling, or prolonged sitting.
- Trial name
- NCT06502795
- Testing
- Protected Range Quadriceps Strengthening group, Patient-Guided Range Quadriceps Strengthening group
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Universidade Federal do Ceara
Pain, Postoperative, Muscle Weakness
Low-Volume Pericapsular Nerve Group (PENG) Block With Dexamethasone vs Standard-Volume PENG Block After Total Hip Arthroplasty
The goal of this clinical trial is to compare two regimens of the pericapsular nerve group (PENG) block, an ultrasound-guided injection of local anaesthetic targeting the nerves supplying the front of the hip joint, for…
- Conditions
- Pain, Postoperative, Muscle Weakness, Arthroplasty, Replacement, Hip
- Trial name
- NCT07855341
- Testing
- Pericapsular nerve group (PENG) block, Bupivacaine, Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University