Clinical trials: RHINOPLASTY, open to volunteers
Septal Extension Graft in Rhinoplasty
Outcomes Assessment of Septal Extension Graft Versus Columellar Strut Graft in Rhinoplasty.
Nose is an important aesthetic landmark with its length, width, shape, and position in the middle of the face. Rhinoplasty is now one of the most common rhinological procedures with both functional and aesthetic aspects.
- Trial name
- NCT06958575
- Testing
- Septal extension graft, Columellar strut
- Volunteers
- 60 people
- Sponsor
- Assiut University
Surgery, Postoperative Blood Loss
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
This study will be a prospective randomized study to evaluate the effect of tranexamic acid (TXA) use on intraoperative and postoperative outcomes among patients undergoing rhinoplasty by two Facial Plastic surgeons at…
- Trial name
- NCT05774717
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Head and Neck Surgery, Plastic Surgery
Preoperative Maxillary Nerve Block and Remifentanil Use in Septorhinoplasty
Septorhinoplasty is generally a prolonged surgical procedure that frequently involves osteotomy, which may lead to increased intraoperative remifentanil requirements.
- Conditions
- Head and Neck Surgery, Plastic Surgery, Rhinoplasty, Pain
- Trial name
- PRISM (NCT07233538)
- Testing
- Maxillary block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Septal Extension Graft in Rhinoplasty, Primary Rhinoplasty
Unilateral Septal Extension Graft and Bilateral Septal Extension Graft in Droopy Tip and Its Effect on Tip Deviation
This study aims to compare between the unilateral and bilateral septal extension graft and evaluate the effect of each of them on tip deviation.
- Conditions
- Septal Extension Graft in Rhinoplasty, Primary Rhinoplasty, Nasal Projection
- Trial name
- NCT07446426
- Testing
- Unilateral septal extension graft, Bilateral septal extension graft
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Tanta University
Nasal Valve Collapse, Nose Enhancement
Cartilage Remodeling Using Low-Temperature Radiofrequency for Nasal Airway Reconstruction
The goal of this study is to evaluate the efficacy of using the Vivaer low-temperature radio-frequency (LTRF) device to reshape ex-vivo human nasal or auricular cartilage for use in cosmetic and functional septorhinoplasty.
- Trial name
- NCT07032675
- Testing
- Low-temperature radio-frequency reshaping of autologous cartilage nasal and/or auricular cartilage
- Where
- 6 sites in United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Emergence Agitation
Prevention of Emergence Agitation in Rhinoplasty With Subanesthetic Propofol and Single-Dose Dexmedetomidine: A Prospective Double-Blind Clinical Study
To compare of prevention of emergence agitation in rhinoplasty with subanesthetic propofol and single dose dexmedetomidine
- Trial name
- NCT07144007
- Testing
- Dexmedetomidine, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Rhinoplasty, Nasal Surgery
Lateral Crural Steal With Columellar Strut Graft in Primary Open Rhinoplasty
The goal of this clinical trial is to assess the effect of Lateral crural steal with Columellar strut graft done in Primary Open Rhinoplasty and its long-term sustainability on nasal tip projection and nasal tip rotation.
- Conditions
- Rhinoplasty, Nasal Surgery, Aesthetic Outcomes
- Trial name
- LCS/CS (NCT07317947)
- Testing
- Lateral crural steal with columellar strut graft in Primary Open Rhinoplasty
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Kafrelsheikh University
Pain, Postoperative
Screen Addiction and Postoperative Pain
Excessive or problematic smartphone use has become increasingly common and has been associated with various psychological and physical health consequences, including anxiety, depressive symptoms, reduced sleep quality…
- Trial name
- NCT07242872
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Pain, Postoperative
Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia
The purpose of this study is to find out which pain medication is more effective in reducing pain after nose surgery (rhinoplasty).
- Trial name
- NCT07689162
- Testing
- Standard Bupivacaine, Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Washington University School of Medicine
Nasal Septum Deviation, Rhinoplasty
Effect of Controlled Hypotension on GFAP and Cognition in Rhinoplasty
This prospective observational study aims to evaluate the neurological safety of controlled hypotension (Mean Arterial Pressure 50-65 mmHg) during elective rhinoplasty.
- Conditions
- Nasal Septum Deviation, Rhinoplasty, Induced Hypotension
- Trial name
- NCT07699133
- Testing
- Controlled Hypotension (Standard of Care)
- Volunteers
- 40 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Rhinoplasty, Edema
Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre
This single-centre, randomized, double-blind, sham-controlled clinical trial evaluates whether preoperative photobiomodulation (PBM) with red and infrared light can reduce early postoperative periorbital edema in patients…
- Trial name
- NCT07033039
- Testing
- Photobiomodulation, Simulation of Photobiomodulation, Standard treatment protocol
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Rhinoplasty, Pain Management
Efficacy of Liposomal Bupivacaine Post Septorhinoplasty
The objective of this study is to determine if there is a difference in post-operative pain after septorhinoplasty when long-acting liposomal bupivacaine is used for local anesthesia compared to other standard local anesthetic…
- Trial name
- NCT05964868
- Testing
- Liposomal Bupivacaine, 0.25% bupivacaine with 1:200,000 epinephrine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Jessyka Lighthall
Nasal Obstruction, Nasal Surgical Procedures
Antibiotic Prophylaxis in Rhinoplasty
This study compares the efficacy of a single intra-operative (intravenous) dose of "cephalexin" (first generation cephalosporin) or "clindamycin" (lincosamides), alone versus both intra-operative (intravenous) dose of…
- Trial name
- NCT04194216
- Testing
- Intra-operative single intravenous(iv) dose of "cephalexin" 2 g or "clindamycin" 900 mg., Intra-operative single dose (iv) of "cephalexin" 2 g or "clindamycin" 900 mg and postoperative oral dose of "cephalexin" 250mg (every 4 hours) or "clindamycin" 150mg(every 6 hours) for 3 days
- Where
- United States
- Volunteers
- 864 people
- Sponsor
- Stanford University
Post Operative Pain
Dexamethasone vs Dexmedetomidine in Sphenopalatine Ganglion Block for Rhinoplasty Pain
This study will test the effect of adding dexamethasone versus dexmedetomidine as adjuvants to bupivacaine in sphenopalatine ganglion block used for pain after rhinoplasty
- Trial name
- NCT07380139
- Testing
- Dexamedomedine, Dexamethasone, Bubpivacaine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Nasal Deformity, Rhinoplasty
Patient-Reported Outcomes and Complications After Structural Rhinoplasty Using Septal Extension Grafts
Structural rhinoplasty with septal extension graft (SEG) is commonly used to achieve stable nasal tip support and predictable long-term outcomes.
- Conditions
- Nasal Deformity, Rhinoplasty, Nasal Obstruction
- Trial name
- SEG-PROM (NCT07531810)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Cumhuriyet University Hospital
Intraoperative, Ketamine
Intraoperative Combination of Ketamine and Magnesium Sulfate Infusions on Postoperative Analgesia in Open Rhinoplasty
The study aims to evaluate the effectiveness of intraoperative combination of ketamine and magnesium sulfate infusions on postoperative analgesia in patients undergoing open rhinoplasty.
- Conditions
- Intraoperative, Ketamine, Magnesium Sulfate, Postoperative Analgesia
- Trial name
- NCT06966518
- Testing
- Ketamine and Magnesium Sulfate, Saline 0.9%
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Rhinoplasty, AI (Artificial Intelligence)
AI in Assessing Aesthetic Outcomes in Rhinoplasty
This study aims to thoroughly assess the predictive accuracy of artificial intelligence-based nasal outcome simulations by comparing AI-generated preoperative predictions with objective postoperative nasal morphology using…
- Trial name
- NCT07580573
- Testing
- AI
- Volunteers
- 20 people
- Sponsor
- Assiut University
Cleft Lip and Palate, Rhinoplasty
Single Stage Versus Multiple Staged Repair of Nasal & Alveolar Deformities in Patients With Cleft Lip and Palate
Cleft lip and palate patients are commonly seen among maxillofacial patients. Patients with cleft lip and palate have evident cosmetic nasal deformities.
- Trial name
- NCT06510881
- Testing
- Rhinoplasty with or without cleft alveolus repair
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cleft Lip and Cleft Palate
Aesthetic and Functional Self-Assessment Following Rhinoseptoplasty in Patients With Unilateral Cleft Lip and Palate
Secondary rhino-septoplasty in unilateral cleft lip and palate is the treatment of choice for the correction of aesthetic deformities and the functional impact on ventilation nasal. It remains a difficult treatment.
- Trial name
- RHINOFENTE (NCT07048418)
- Testing
- Mailing and completing CLEFT-Q and NOSE questionnaires
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Rhinoplasty, Nasal Obstruction
Outcome Analysis in Septorhinoplasty
A prospective observational cohort study that measures pre- and postoperative outcome of septorhinoplasty by means of patient-related outcome measures (PROMS: NOSE, FACE-Q, Utrecht Questionnaire, SCHNOS and BDDQ-AS) as well as…
- Conditions
- Rhinoplasty, Nasal Obstruction, Esthetics
- Trial name
- NCT03925389
- Testing
- External septorhinoplasty
- Where
- Belgium
- Volunteers
- 750 people
- Sponsor
- FRANK DECLAU