Clinical trials: Radicular Pain, open to volunteers
Herniated Disc
Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain
The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications.
- Trial name
- NCT07036445
- Testing
- Epidural Steroid Injection, Epidural platelet-rich plasma injection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Lumbar Disc Herniation, Lumbar Radiculopathy
PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation
This prospective observational study aims to evaluate the clinical outcomes of patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD).
- Trial name
- PLDD-TFESI (NCT07400068)
- Testing
- Percutaneous Laser Disc Decompression (PLDD), Transforaminal Anterior Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Mersin University
Disc Herniation
Discogen for Low Back Pain
This study will be a double-blinded, two-arm, prospective, randomized controlled pilot feasibility study in 40 evaluable subjects (20 in each arm) at one study site within the United States.
- Trial name
- NCT06611397
- Testing
- Discogen Low pulsed ultrasound treatment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Columbia University
Radiculopathy, Lumbosacral Region, Back Pain With Radiation
Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.
This will be a placebo controlled, randomized, double-blind, comparative effectiveness study, in which we patients are enrolled during an emergency department (ED) visit for acute radicular low back pain (LBP) and followed by…
- Conditions
- Radiculopathy, Lumbosacral Region, Back Pain With Radiation, Low Back Pain
- Trial name
- NCT05721027
- Testing
- Ibuprofen 400 mg, Dexamethasone Oral, Educational Intervention
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Lumbosacral Radicular Pain, Lumbar Radiculopathy
Determination of Sensitivity and Specificity of Straight Leg Raise Test Via Transforaminal Nerve Root Block
This study aims to evaluate the diagnostic accuracy of the straight leg raise test in patients with suspected lumbosacral radicular pain.
- Conditions
- Lumbosacral Radicular Pain, Lumbar Radiculopathy, Straight Leg Raise
- Trial name
- NCT07696312
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Marmara University
Sciatica, Lumbosacral Radiculopathy
Three CT Signs of Nerve-root Suffering in Low-back Sciatica: a Study of Their Frequency in Patients Referred for CT-guided Nerve-root Infiltration.
Retrospective, observational, single-centre study conducted at Nice University Hospital (Pasteur 2), Department of Diagnostic and Interventional Radiology.
- Conditions
- Sciatica, Lumbosacral Radiculopathy, Low Back Pain
- Trial name
- NCT07690449
- Testing
- Pre-infiltration lumbar planning CT scan - reading of the three nerve-root signs
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Radiculopathy Lumbar, Radiculopathy Sacral
The Selective Intraperineural Nerve Root Block Study
Before lumbosacral decompression surgery for radicular pain, selective nerve root block(SNRB) is a common procedure to identify the responsible compressed nerve root(RCNR) and predict surgical outcomes.
- Conditions
- Radiculopathy Lumbar, Radiculopathy Sacral, Radiculopathy Multiple Sites, Herniated Disc
- Trial name
- SINRBS (NCT07531485)
- Testing
- Selective Intraperineural Nerve Root Block(SINRB), single-level lumbar decompression surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xi'an Honghui Hospital
Type 2 Diabetes (T2DM), Hyperglycemia
CGM-Based Glycemic Analysis After ESI
The goal of this clinical study is to learn how blood glucose levels change after an epidural steroid injection (ESI) with dexamethasone in adults.
- Conditions
- Type 2 Diabetes (T2DM), Hyperglycemia, Radicular Pain, Spinal Stenosis
- Trial name
- CGMSteroid (NCT07280780)
- Testing
- Epidural Steroid Injection, Continuous Glucose Monitoring
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Korea University Anam Hospital
Cervical Radicular Pain, Cervical Radiculopathy
Predictors of Response to Manual Physiotherapy Using Somatosensory Profiles in Patients With Cervicobrachial Pain
The goal of this clinical trial is to investigate about the characteristics that predict response to physiotherapy treatment in patients with nerve related neck arm pain.
- Conditions
- Cervical Radicular Pain, Cervical Radiculopathy, Cervical Pain
- Trial name
- NCT06069362
- Testing
- Manual physiotherapy and neurodynamic exercises
- Where
- Spain
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Unilateral S1 Nerve Root Pain
Comparison of Efficacy of Caudal Versus Transforaminal Epidural Steroid Injections in Unilateral S1 Nerve Root Pain: A Randomized Controlled Trial
This study compares caudal and transforaminal epidural steroid injections for treating unilateral S1 nerve root pain. It evaluates pain relief, functional improvement, treatment satisfaction, quality of life, and complications…
- Trial name
- NCT07833553
- Testing
- Caudal Epidural Steroid Injection (CEI), Transforaminal Epidural Steroid Injection (TFI)
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- University of Health Sciences Lahore
Chronic Neuropathic Pain, Radiculopathy
Hypersound Treatment for Chronic Neuropathic and Radicular Pain
This study will evaluate whether the investigational Hypersound system reduces pain in adults with chronic neuropathic or radicular pain.
- Conditions
- Chronic Neuropathic Pain, Radiculopathy, Sciatica, Peripheral Neuropathic Pain
- Trial name
- NCT07831447
- Testing
- Hypersound RF-PNS system
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Hypersound Medical Inc
Chronic Neck Pain, Radicular Pain
Reliability of MRI and Ultrasound in Cervical Epidural Needle Depth Estimation
This study aims to evaluate the reliability of magnetic resonance imaging (MRI) and ultrasound (USG) in predicting needle depth during cervical epidural injections, compared to fluoroscopy.
- Conditions
- Chronic Neck Pain, Radicular Pain, Cervical Epidural Injection
- Trial name
- CERV-MRI-USG (NCT06747663)
- Testing
- Needle Depth Measurement Using MRI, Ultrasound, and Fluoroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Damla Yürük
Postoperative Pain, Breast Cancer
RISS Versus SPSIP Block in Modified Radical Mastectomy
This prospective randomized double-blind controlled trial aims to compare the postoperative analgesic efficacy and dermatomal spread of rhomboid intercostal-subserratus plane (RISS) block and serratus posterior superior…
- Trial name
- RSMRM (NCT07659990)
- Testing
- Rhomboid Intercostal-Subserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Cervical Radicular Pain
45 V vs 60 V Pulsed Radiofrequency of the Cervical Dorsal Root Ganglion for Cervical Radicular Pain
This study aims to compare the clinical outcomes of 45 V and 60 V pulsed radiofrequency (PRF) applied to the cervical dorsal root ganglion (DRG) in patients with cervical radicular pain.
- Trial name
- NCT07744438
- Testing
- 45 V cervical dorsal root ganglion pulsed radiofrequency, 60 V cervical dorsal root ganglion pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Ankara Etlik City Hospital
Low Back Pain, Radicular Syndrome
Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal Disorders
This pilot randomized controlled trial aims to compare the clinical effectiveness of advanced high-intensity physical therapy modalities with conventional physical therapy in patients suffering from musculoskeletal disorders.
- Conditions
- Low Back Pain, Radicular Syndrome, Sacroiliac Joint Dysfunction, Shoulder Impingement Syndrome
- Trial name
- NCT07903142
- Testing
- Repetitive Peripheral Magnetic Stimulation (rPMS), High-Intensity Laser Therapy (HIL), Extracorporeal Shockwave Therapy (ESWT)
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- BTL Industries Ltd.
Cervical Radiculopathy, Cervical Radicular Pain
Investigation of the Effects of Interlaminar Epidural Steroid Injection on Upper Extremity Proprioception in Patients With Chronic Cervical Radiculopathy
Cervical radiculopathy is a common condition caused by irritation or compression of cervical nerve roots, often leading to unilateral neuropathic pain and functional impairment.
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Proprioception
- Trial name
- NCT07307846
- Testing
- Interlaminar Epidural Steroid Injection (ILESI)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Marmara University
Lumbosacral Radiculopathy, Neuropathic Pain From Lumbosacral Radiculopathy
TFESI and Neuropathic Pain in Lumbosacral Radiculopathy
Patients with lumbosacral radiculopathy frequently experience neuropathic pain due to nerve root compression. Transforaminal epidural steroid injection (TFESI) is commonly used for pain relief in these patients.
- Conditions
- Lumbosacral Radiculopathy, Neuropathic Pain From Lumbosacral Radiculopathy, Disc Herniation With Radiculopathy
- Trial name
- NCT07799155
- Testing
- Transforaminal Epidural Steroid Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Cervical Radicular Pain
Neuromuscular Re-education on Pain, ROM and Disability in Cervical Radiculopathy
This study explores the effectiveness of Neuromuscular Re-education compared to conventional therapies in managing pain, range of motion, and disability in patients with Cervical Radiculopathy
- Trial name
- NCT07506200
- Testing
- Neuromuscular Re education, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Disc Herniation
Caudal Neuroplasty Using Epidural Catheter Combined with Pulsed Radiofrequency (versus Pulsed Radiofrequency Alone
Evaluating the superiority of caudal neuroplasty using epidural catheter (Perifix® Complete Set 16 G) combined with Pulsed Radiofrequency (PRF) versus Pulsed Radiofrequency (PRF) alone targeting the dorsal root ganglion In…
- Trial name
- NCT06711419
- Testing
- f caudal neuroplasty using epidural catheter combined with Pulsed Radiofrequency (PRF) versus Pulsed Radiofrequency (PRF) alone
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Peripheral Neurogenic Pain
Slump Lateral Bending Test Diagnostic Accuracy in Lumbar Radicular Pain
This observational diagnostic accuracy study will evaluate the ability of the Slump Lateral Bending Test to identify patients with suspected peripheral neurogenic pain or neural mechanosensitivity.
- Trial name
- NCT07662421
- Where
- Italy
- Volunteers
- 280 people
- Sponsor
- Fisiopoint Parma Physiotherapy