Clinical trials: Randomised Clinical Trial
Tympanic Membrane Perforation
Comparison Tympanoplasty With Membrane Amniotic and Autologous Fascia
The tympanic membrane separates the middle and the outer ear from each other and consists of three layers. The outer layer is covered with squamous epithelium, a thick basement membrane in the middle and an inner Mucosal layer.
- Trial name
- NCT03569969
- Testing
- device: Tympanoplasty with Membrane Amniotic, Tympanoplasty With Autologous Fascia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mohammad Sadegh Bagheri Baghdasht
Healthy
Time of Treatment in HALL Technique Vs ART
The goal of this clinical trial is to assess the time of treatment of Hall Technique versus Atraumatic Restorative Technique in the management of carious primary molars.
- Trial name
- NCT06594770
- Testing
- Atraumatic Restorative Treatment, Hall technique
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Elderly, Sleep Quality
The Effect of a Foot Bath on Sleep Quality in The Elderly
This study was carried out as a single-blind randomized controlled study to investigate the effect of a foot bath on sleep quality in the elderly.
- Conditions
- Elderly, Sleep Quality, Complementary Therapy, Chronic Disease
- Trial name
- NCT05572554
- Testing
- Foot Bath Group
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hatice Demirağ, Ph.D
Japanese Encephalitis
Safety and Efficacy Study of ChimeriVax™-JE and JE Inactivated Mouse Brain Vaccine in Children of Descending Age
This randomised, double-blind study is to be conducted on 96 subjects at multiple sites in India. Subjects will be enrolled by age group and randomised to either ChimeriVax™-JE (JE-CV) or JE Mouse Brain Derived Vaccine (JE-MBDV).
- Trial name
- NCT00441259
- Testing
- ChimeriVax™-JE, Japanese Encephalitis Inactivated Mouse Brain Vaccine
- Where
- 3 sites in India
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Sanofi
Kinesiology Taping
Acute Effects of Kinesiology Taping in Handball Players
The aim of this randomised placebo-controlled study was to investigate the acute effect of kinesiology taping in the gastro-soleus muscle group of handball players.
- Trial name
- NCT05691946
- Testing
- Kinesiology Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Amasya University
Gummy Smile, Altered Passive Eruption of Teeth
Clinical Evaluation of Gingivalstat Approach Compared to Conventional Esthetic Crown Lengthening on the Stability of The Gingival Margin in Patients With Altered Passive Eruption.
When performing crown lengthening surgery, especially in the esthetic zone, the positional stability of gingival tissues is considered a prime important goal.
- Conditions
- Gummy Smile, Altered Passive Eruption of Teeth, Healthy Participants
- Trial name
- NCT07041541
- Testing
- Esthetic Crown Lengthening, Esthetic Crown Lengthening using GingivalStat approach
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Uterine Cervical Dysplasia, Papillomavirus Infections
Impact of AV2 Antiviral Drug on the Treatment of HPV-associated Lesions of the Uterine Cervix
1. Introduction Cervical cancer (CC) is a major public health problem in Low-income countries (LICs), particularly in the Democratic Republic of the Congo (DRC), where the estimated number of cases is 3839 per year. (WHO, 2010).
- Trial name
- KINVAV (NCT02346227)
- Testing
- AV2
- Where
- Democratic Republic of the Congo
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Jean-Pierre Van geertruyden
Other Instability, Ankle and Foot
The Effect of Strain-counterstrain on Ankle Instability
This study seeks to determine the effectiveness of Strain Counterstrain in the treatment of chronic ankle instability.
- Trial name
- NCT02025569
- Testing
- Strain Counterstrain
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Long Island University
Chronic, Infection
Pulpectomy of Primary Molars With Rotary Instrumentation Versus Manual Instrumentation
One of the major concerns in pediatric dentistry is premature loss of necrotic primary teeth which may cause a deleterious effect on the growth of the facial skeletal complex.
- Trial name
- NCT03964766
- Testing
- Rotary instrumentation, Hand instrumentation
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypertension
Approaches to Reduce Clinical Inertia in Hypertension in the Dominican Republic
The purpose of this cluster randomized control trial is to test whether a multimodality strategy that includes an educational on-line course and performance feedback reports is effective to reduce clinical inertia in the…
- Trial name
- ARCH DR (NCT03954951)
- Testing
- Multimodality behavioral strategy
- Where
- Dominican Republic
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Non-surgical Retreatment
Effects of Different NiTi Systems on Postoperative Pain and Operation Time in Nonsurgical Endodontic Retreatment
This prospective, randomized, single-center, single-blind clinical trial evaluated the effects of different nickel-titanium retreatment and final shaping systems on postoperative pain and operation time during single-visit…
- Trial name
- NiTi-RETREAT (NCT07783945)
- Testing
- ProTaper Universal Retreatment System, MicroMega REMOVER, ProTaper Next
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Role, Nurses
Clarification of Nurses' Expected Role in Health Promotion
The purpose of this study is to implement and evaluate ROLE-AP, a multi-component program to clarify primary care nurses' expected role in health promotion.
- Trial name
- ROLE-AP (NCT04726696)
- Testing
- ROLE-AP programme
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Gingivitis, Gingivitis; Chronic
A Multicentre Randomised Controlled Trial Evaluating the Efficacy of the SMILE™ Module for Improving Short-term Periodontal Outcomes, Compliance, and Acceptability Among Clinical Dental Students
This multicentre randomised controlled trial aims to evaluate the efficacy and safety of the SMILETM (Siwak Method for Integrated Lifestyle Enhancement) module in improving short-term periodontal outcomes, oral hygiene behaviour…
- Trial name
- SMILE (NCT07702383)
- Testing
- SMILE Module, Conventional Toothbrushing Module
- Where
- 4 sites in Malaysia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Diet Habit
The OPTIMISE Intervention for Reducing Meat Consumption in UK Adult Meat-eaters
This randomised controlled trial will test the effectiveness of a self-regulation intervention for reducing meat consumption in people who are motivated to change their meat-eating habits.
- Trial name
- OPTIMISE (NCT04961216)
- Testing
- OPTIMISE
- Where
- United Kingdom
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Emergencies, Injuries
The Impact of First Aid Blended Learning Training on Learning Outcomes and Helping Behaviour of Adult Laypeople in Rwanda
The goal of this study is to assess the impact of a first aid training delivered through a blended learning approach on learning outcomes and helping behaviour in adult laypeople in Rwanda.
- Conditions
- Emergencies, Injuries, Illness Physical
- Trial name
- NCT06003504
- Testing
- First aid training with blended learning approach, First aid training with face-to-face approach
- Where
- Rwanda
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Centre for Evidence-Based Practice, Belgium
Stress
Feasibility and Efficacy of a Digital Training Intervention to Increase Reward Sensitivity- Imager
Development and feasibility test of an Ecological Momentary Intervention (EMI) - Imager, to promote and improve stress resilience, specifically to increase reward sensitivity.
- Trial name
- IMAGER (NCT05623826)
- Testing
- Cognitive- behavioral imagery-based training
- Where
- Switzerland
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Secondary Caries
Effect of Bioactive Restorative Materials on Secondary Caries Prevention
This manuscript presents a 24-month randomised clinical trial evaluating the effectiveness of bioactive restorative materials in preventing secondary caries compared with conventional composite restorations.
- Trial name
- BARM (NCT07619378)
- Testing
- Fuji IX GP Glass Ionomer Cement, Beautifil II Giomer, Cention N
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jouf University
Psychological Stress, Anxiety
Effects of L-Theanine and Hericium Erinaceus Gummies on Psychological, Cognitive, and Sleep Quality in University Students
The THEA-HEAL Trial is an 8-week randomized controlled study investigating the effects of a daily gummy supplement containing L-theanine and Hericium erinaceus (Lion's mane mushroom) extract on stress, anxiety, cognitive…
- Conditions
- Psychological Stress, Anxiety, Depression, Sleep Quality
- Trial name
- THEA-HEAL (NCT07665840)
- Testing
- gummy intervention
- Where
- Malaysia
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Nottingham Malaysia
Pain
Incidence of Flare-ups and Apical Healing After Single-visit or Two-visits Treatment.
Aim to compare Incidence of flare-ups and apical healing after single-visit or two-visits treatment of teeth with necrotic pulp and apical periodontitis after a two-year control period.
- Trial name
- FlareUp (NCT02815189)
- Testing
- Ibuprofen for post operative pain, Acetaminophen 325 mg for Flare up
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Hypercholesterolemia
Investigating Effects of a Novel Nutraceutical on Hypercholesterolaemia in Australian Adults
To evaluate the effects of daily consumption of 3 capsules of Swisse Nutra+ Cholesterol Balance on serum LDL-cholesterol in adults with hypercholesterolaemia compared to placebo over four months.
- Trial name
- CLoNE (NCT04783714)
- Testing
- Swisse Nutra+ Cholesterol Balance
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Swisse Wellness Pty Ltd
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