Clinical trials: Randomised Clinical Trial
Dental Crowding, Smile Arc Correction
A Study to Evaluate the Relationship Between Two Bracket System and Their Contribution to Initial Alignment of Maxillary Anteriors - De Crowding, Smile Arc Protection.
The goal of this clinical trial is to compare the two orthodontic bracket systems namely MBT and the Pitts21 for maxillary anterior decrowding, initial alignment as well as the smile arc correction in 6 month period.
- Conditions
- Dental Crowding, Smile Arc Correction, Maxillary Crowded Teeth
- Trial name
- NCT07712055
- Testing
- Pitts 21 bracket system, MBT bracket system
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Srinivas College of Dental Sciences
Obesity, Overweight
Microvascular and Metabolic Effects of High-intensity Interval Exercise Training
The study investigates the effects of high intensity interval training (HIIT) versus continuous training (CT), combined or not with fasting, on capillary density, microvascular function, cardiometabolic risk markers, functional…
- Conditions
- Obesity, Overweight, Physical Activity
- Trial name
- HIIT-FAST (NCT03236285)
- Testing
- High-intensity interval exercise training in the fed state, Continous exercise training in the fed state, High-intensity interval exercise training in the fasting state
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Maltreatment by Spouse or Partner
Impact of Microfinance and Participatory Gender Training for Women in Reducing Intimate Partner Violence
Violence against women and girls is increasingly recognized as a major global public health and development concern. However, evidence on what forms of intervention should be prioritised is severely lacking.
- Trial name
- MAISHA (NCT02592252)
- Testing
- Participatory gender training, Microfinance
- Where
- Tanzania
- Volunteers
- 2,640 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Malaria, Anemia
Intermittent Antimalaria Treatment With SP in African Children
intermittent preventive treatment with SP in children to evaluate efficacy and safety of this drug combination in children in northern Ghana
- Trial name
- NCT00168948
- Testing
- Sulfadoxin (12.5) Pyrimethamine (250 mg)
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy Volunteer Study
AZD8566 Food Effect/Microtracer Study
A study designed to look at how the drug AZD8566 is taken up by the body when given with or without food. In some subjects a comparison will be made with a very small labelled microdose given into a vein.
- Trial name
- NCT00866385
- Testing
- AZD8566, AZD8566 IV carbon labelled
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Feeding Behavior, Gastrointestinal Microbiome
The Timing of Main Meal Consumption Effect on Gut Microbiota and Host
The interplay between diet and the gut microbiota has been implicated in the onset of cardiovascular disease. The gut microbiota displays diurnal rhythms, which may be influenced by meal timing.
- Conditions
- Feeding Behavior, Gastrointestinal Microbiome, Diet, Meal Time
- Trial name
- TIMC (NCT03949543)
- Testing
- Large Lunch Intervention, Large Dinner Intervention
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Orthodontic Relapse, Malocclusion
3D-Printed vs Conventional Fixed Retainers After Orthodontic Treatment
This randomized clinical trial aims to compare the clinical performance of two types of three-dimensionally printed fixed retainers (Cobalt-Chromium and Titanium Grade 5) with the conventional multistranded stainless steel fixed…
- Trial name
- NCT07730476
- Testing
- Conventional Multistranded Stainless Steel Fixed Retainer, 3D-Printed Cobalt-Chromium Fixed Retainer, 3D-Printed Titanium Fixed Retainer
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Indirect Restoration of Badly Broken Vital Teeth
Internal Fit Evaluation of Indirect Restorations Using Cone Beam CT (CBCT)
this study was conducted to evaluate the internal fit of indirect restoration fabricated from CAD/CAM composite blocks versus ceramic blocks in badly broken vital teeth using cone beam CT
- Trial name
- NCT04784676
- Testing
- restoration
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neuropathic Pain, Peripheral Neuropathy
Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management
Compare Axon Therapy using transcutaneous magnetic stimulation (tMS) against conventional medical management in treating post-traumatic peripheral neuropathic pain (PTPNP).
- Trial name
- NCT04795635
- Testing
- CMM + Axon Therapy
- Where
- 3 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- NeuraLace Medical, Inc.
Stress Disorders, Post-Traumatic
A Randomized Clinical Trial of Cognitive-Behavioral Treatment for Post-Traumatic Stress Disorders in Women
The purpose of the proposed DVA cooperative study is to evaluate the efficacy of exposure therapy for treating PTSD and associated problems in female veterans and active duty military personnel.
- Trial name
- NCT00032617
- Testing
- Prolonged Exposure, Present Centered Therapy
- Where
- 13 sites in United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Sexual Health, Health Literacy
Flipped Classroom Sexual Health Education Trial
Sexual health is an integral component of individuals' physical, emotional, mental, and social well-being. Lack of knowledge and cultural taboos negatively affect individuals' ability to make informed decisions and adopt…
- Conditions
- Sexual Health, Health Literacy, Health Education, Flipped Classroom Model in Teaching
- Trial name
- NCT07306208
- Testing
- Flipped learning
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Mouthguard Use Orofacial Injuries Prevention 3D Printed Mouthguard Traditional Custom-made Mouthguard Occlusal Thickness Changes
Comparative Assessment of Thickness Changes in 3D-Printed vs. Custom-Made Mouth Guards for Children in Contact Sports
This study aims to compare changes in the thickness of traditional and 3D-printed custom mouth guards in pediatric athletes who participate in contact sports.
- Trial name
- NCT07000435
- Testing
- 3D printed custom-made mouth guards, Traditional custom-made mouth guards
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Composite Post, Intracanal Reinfocement
Evaluation of Intracanal Reinforcement with Short Composite Post in Upper Primary Incisors with Severly Carious Teeth As in Early Childhood Caries Cases Using Randomized Clinical Trial
Severely damaged incisors may lead to difficulty in speech, decreased masticatory efficiency, abnormal tongue habits, subsequent malocclusions, and psychological and self-esteem problems.
- Trial name
- NCT06740643
- Testing
- intracanal reinforcement using short composite post, no intracanal reinforcement
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Cairo University
Aging Well
Telematic Dance Intervention on Quality of Life of Older
The aim of this study is to analyse the effectiveness of a telematic dance intervention on the quality of life of older people. This project is a controlled, randomized clinical trial.
- Trial name
- NCT04681976
- Testing
- Telematic dance program
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Diet Habit
A Digital Approach to Improving Carbohydrate Periodisation Behaviours in Athlete: SMART+ Study
The carbohydrate periodisation framework is a widely accepted nutritional intervention strategy in the field of sports nutrition.
- Trial name
- NCT04487015
- Testing
- MP, Call, MesC
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Fatigue, Anesthesia
Effect of Fatigue on Regional Anaesthesia Task
The adverse effects of sleep related fatigue are significant, impacting on doctors' health, wellbeing, performance and ultimately their safety and that of their patients'.
- Trial name
- NCT04711499
- Testing
- Fatigue
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Gummy Smile Due to Hypermobile Upper Lip
Satisfaction Of Adult Patients With Gummy Smile Treated By Botulinum Toxin A Injection
The aim of the proposal study is to answer the question of how to manage gummy smiles due to hypermobile upper lip with less invasive and low risk level procedure .
- Trial name
- NCT03186547
- Testing
- Botulinum Toxin A Injection, Modified Lip Repositioning Surgery
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Health
Quaternary Ammonium Methacryloxy Silicate-containing Acrylic Resin
One of the major challenges in orthodontic treatment is long-term stability. Because removable retainers are worn for at least one year, bacteria and fungi may accumulate on the retainers in the form of multi-species plaque…
- Trial name
- NCT02525458
- Testing
- QAMS-containing PMMA, QAMS-free PMMA
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Frank Tay, BDSc (Hons), PhD
Necrotic Primary Molars
Obturation Quality in Primary Molars
Forty cases of necrotic primary molars in children aged 4-8 years were selected to compare the effect of manual versus rotary pulpectomy regarding parental acceptance and obturation quality.
- Trial name
- RCT (NCT06157021)
- Testing
- Rotary pulpectomy, Manual pulpectomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anxiety Disorders and Symptoms
Evaluation of the Minimalist Music and Birdsongs in the Anxiety of Nursing Professionals in Oncology
This project aims to investigate the effects of an intervention involving minimalist piano music and bird singing on the anxiety of nursing professionals working in the Oncology sector of a hospital.
- Trial name
- NCT05510921
- Testing
- Minimalist music group, Minimalist music + birdsongs group
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
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