Clinical trials: Randomized Clinical Trial
Rabies
A Study to Assess the Safety, Reactogenicity and Immune Response of CureVac's Candidate Rabies mRNA Vaccine in Healthy Adults
The primary objective of this clinical study is to assess the safety, and reactogenicity of CV7202 mRNA-rabies vaccine in healthy adults. Immunogenicity is also assessed.
- Trial name
- NCT03713086
- Testing
- Rabipur®, Rabies mRNA vaccine CV7202
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- CureVac
Whooping Cough
Viaskin Pertussis Vaccine Trial
The study is a Phase I, first in human, monocenter study, aiming at assessing the safety and immunogenicity of a genetically detoxified pertussis toxin (PT) when administered via the cutaneous route with Viaskin patches to…
- Trial name
- NCT03035370
- Testing
- Viaskin PT 25 mcg, Viaskin PT 50 mcg, Boostrix™
- Where
- Switzerland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- DBV Technologies
Video Laryngoscopic Device Usage in Novice Users
Comparison Study of the McGrath MAC Video Laryngoscope With the King Vision
In this study, the investigators compare the effectiveness of two relatively new video laryngoscopes, McGrath MAC (Covidien, Dublin Ireland) and the King Vision (King Systems, Noblesville, IN), by practitioners experienced in…
- Trial name
- NCT02316769
- Testing
- King Vision video laryngoscope, McGrath MAC video laryngoscope
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Healthy
Video Coaching as an Efficient Teaching Method for Surgical Residents
The purpose of this study is to determine if video coaching is an efficient way of teaching surgical skills outside of the operating room for surgical residents.
- Trial name
- NCT02529254
- Testing
- Video coaching session
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Sleep Restriction
The Effects of Individualised Short-term Sleep Restriction on Tactical Performance
The goal was to evaluate the influence that chronic sleep restriction may have on football players tactical performance during small-sided games.
- Trial name
- NCT06912256
- Testing
- Sleep restriction
- Where
- Portugal
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- José Afonso Coelho Neves
Hyperglycemia
Efficacy and Safety of Angelica Gigas N. Extract on Improvement of Hyperglycemia
This study was conducted to investigate the effects of daily supplementation of Angelica gigas N. extract on improvement of Hyperglycemia .
- Trial name
- NCT03258229
- Testing
- Angelica gigas N. extract
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Complications, Pregnancy
Repeat Antenatal Steroids Trial
A course of steroids given to a mother who is in labor with a premature fetus will reduce the risk of the premature infant dying or having serious complications.
- Trial name
- BEARS (NCT00015002)
- Testing
- Betamethasone
- Where
- 19 sites in United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Mindfulness Based Stress Reduction, Caregiver Burnout
Mindfulness-Based Stress Reduction in Dementia Caregivers
Aims: The study will contribute to our understanding of how the cultivation of caregiver mindfulness might improve their overall relational well-being (Primary Outcome), their psychological well-being (Secondary Outcome), and…
- Conditions
- Mindfulness Based Stress Reduction, Caregiver Burnout, Caregiver Stress Syndrome, Dementia
- Trial name
- MBSR (NCT04977245)
- Testing
- Mindfulness-Based Stress Reduction, Self-Guided Mindfulness eCourse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Running-related Injury
Effect of Shoe Cushioning Position and Properties on Running-related Injury Risk
The main purpose of this project is to investigate the influence of cushioning material at both the rear and the forepart of running shoes on musculoskeletal complaints in leisure-time runners.
- Trial name
- RRI_Interv5 (NCT06384872)
- Testing
- Shoe Cushioning Position and Properties
- Where
- Luxembourg
- Volunteers
- 1,068 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Caregiver Burden, Depressive Symptoms
Cluster RCT of Cognitive Behavioral Therapy to Support Caregivers of Older Adults in Hong Kong
The goal of this cluster randomized controlled trial study is to compare the effectiveness of a novel psychosocial intervention based on Cognitive Behavioral Therapy, lifestyle intervention and effective communication skills in…
- Conditions
- Caregiver Burden, Depressive Symptoms, Quality of Life, Self Efficacy
- Trial name
- NCT06473012
- Testing
- Cognitive Behavioral Therapy for Caregivers of Older Adults, Control intervention for Caregivers of Older Adults
- Where
- Hong Kong
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Exercise-induced Muscle Damage
The Effect of Ischemic Pre-Conditioning on the Rate of Recovery Following Exercise-Induced Muscle Damage
Strenuous exercise or exercise involving eccentric muscle contractions can lead to muscle damage and changes in muscle function; this is known as exercise-induced muscle damage (EIMD).
- Trial name
- NCT01907841
- Testing
- Ischemic Preconditioning
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Testicular Cancer, Testicular Self-Examination
Effects of Testicular Self-Examination Training Methods on Students' Behaviors and Health Beliefs
The goal of this cluster randomized controlled trial is to evaluate and compare the effects of different testicular self-examination (TSE) training methods on university students' health beliefs and self-examination behaviors…
- Conditions
- Testicular Cancer, Testicular Self-Examination, Health Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT07841041
- Testing
- Educational Brochure and Audio Recording, Educational Brochure, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Orthopedic Disorder
Opioid Consumption After Orthopaedic Surgery
This is a randomized controlled study that will involve fellowship-trained board certified orthopaedic surgeons in four different subspecialties (hand surgery, sports surgery, shoulder and elbow surgery, and foot and ankle…
- Trial name
- NCT03173131
- Testing
- Pre-operative opioid counseling
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Laceration Face, Wound Heal
Honey Versus Povidone-iodine on Laceration Wounds
This study evaluates healing time in usage of honey and povidone-iodine over paraffin gauze as dressings in the treatment of acute laceration wounds.
- Conditions
- Laceration Face, Wound Heal, Wounds and Injuries, Laceration Arm
- Trial name
- NCT03641053
- Testing
- Honey, Povidone-iodine, Paraffin gauze
- Where
- Indonesia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- S.K. Lerik General Hospital
Simulation Training, Laparoscopy
Simulator Versus Box Trainer on Laparoscopic Suturing
This is prospective randomized controlled study to compare the proficiency of novices in acquiring laparoscopic suturing skills following either training in a virtual reality simulator or box trainer.
- Trial name
- NCT02770937
- Testing
- Virtual reality simulator, Box trainer, Simbionix
- Where
- Hong Kong
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Elderly Person, Body Composition
Changes in Body Composition When Ingesting a Dairy Compound Enriched With Leucine
Controlled clinical trial, randomized by strata (sex and period of the study), with 6 parallel branches to the study depending on the type of product consumed and the type of physical exercise program performed, double-blind…
- Conditions
- Elderly Person, Body Composition, Physical Exercise
- Trial name
- LEUCI (NCT04345237)
- Testing
- dietary supplement consumption
- Where
- Spain
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Smoking Reduction, Smoking Cessation
Development and Assessment of a Teacher-led Intervention in Preventing Tobacco Use Among the Youth in Ghana
The main purpose of this experimental study is to compare the existing health education program for School Health and Education Program (SHEP) in the Junior High Schools with a new health education model (Smart-Kids') for the…
- Conditions
- Smoking Reduction, Smoking Cessation, Smoking, Tobacco, Smoking Behaviors
- Trial name
- NCT04891939
- Testing
- Health education lessons (Smart-Kid's program), School Health and Education Program (SHEP)
- Volunteers
- 2,314 people, healthy volunteers welcome
- Sponsor
- Ghana Health Services
Diabetes, Anesthesia, Local
Healing Process and Blood Sugar Level Following Local Anesthetic Infiltration With and Without Vasoconstrictor
Evaluating the healing of the extraction socket and the glycemic levels before, and after injection of local anesthesia with and without vasoconstrictor in diabetic patients
- Trial name
- NCT05875519
- Testing
- Local anaesthesia with vasocontrictor (Mepivacaine hydrochloride 20 mg (2%) + Levonordefrin hydrochloride 0.06 mg)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Development, Human, Well-Being
The Impact of Professional Coaching on Early Career Academic Emergency Physicians
This research study is designed to answer the question: How does professional coaching impact early career academic emergency medicine physician goal attainment, leadership strengths, well-being, and burnout?
- Conditions
- Development, Human, Well-Being, Professional Burnout, Goals
- Trial name
- NCT03125330
- Testing
- Professional coaching
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Behavior Problems in Children, Parent-Child Relations
Dino Study: Daily Intervention-based Research on Nurturing Opportunities in Young Children
The goal of this clinical trial is to evaluate the effectiveness of the Incredible Years Dinosaur Program in children aged 4 to 8 years with conduct problems.
- Conditions
- Behavior Problems in Children, Parent-Child Relations, Oppositional Behavior, Social Skills
- Trial name
- Dino (NCT07051642)
- Testing
- Incredible Years Dinosaur Child Program
- Where
- Netherlands
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tilburg University
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