Clinical trials: Randomized Clinical Trial
Necrotic Pulp With Symptomatic Apical Periodontitis
The Impact of Using Different Final Irrigation Modes on Postoperative Pain Following Root Canal Treatment of Non-vital Mandibular First Molar With Periapical Lesion.
The goal of this clinical trial is to learn which rinsing of root canals method works best to lower pain after a root canal in adults.
- Trial name
- NCT07623629
- Testing
- root canal treatment
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Healthy
To Evaluate the Safety, Pharmacokinetic and Pharmacodynamics of JW0061 in Healthy Volunteers
This clinical study is a phase 1, randomized, double-blind, placebo-controlled, dose escalation clinical trial to evaluate the safety, pharmacokinetic and pharmacodynamics of JW0061 following topical application in Korean and…
- Trial name
- NCT07514780
- Testing
- JW0061 SAD, JW0061 MAD
- Where
- South Korea
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- JW Pharmaceutical
Sports Performance, Psychological Adaptation
VR Tennis Training Effects on Psychological Outcomes
This randomized controlled trial examined the effects of an 8-week virtual reality (VR) tennis training intervention on psychological outcomes among Chinese university tennis players.
- Trial name
- NCT07356427
- Testing
- Virtual Reality Tennis Training, Traditional Tennis Training
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Obesity, Overweight
Effectiveness of Online Visit Compared With In-person Clinic Visit on Weight Loss
Online visit and online counseling via telemedicine technology is a new service for obese people who wish to lose weight but because of their active lifestyle and time limitation cannot come to clinic.
- Trial name
- NCT03171961
- Testing
- online visit group, Clinic visit group, self-directed group
- Where
- 2 sites in Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Novindiet Clinic
Drowning
Improving Lifejacket Wear Among Boaters on Lake Albert, Uganda
A cluster randomized trial will be conducted for six months. To avoid covariate imbalance at baseline, stratified permuted block randomization with a 1:1 allocation ratio will be done.
- Trial name
- NCT05337761
- Testing
- Peer-led training on lifejacket wear
- Where
- Uganda
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- Makerere University
Arthropathy of Knee Joint
Motion Analysis of EMP Knee Versus Posterior Stabilized Knee Arthroplasty for Osteoarthritis
The purpose of the current study is to analyze and compare the lower-limb joint motions and muscle activation patterns during activities of daily living as well as self reported health related functional outcomes for patients…
- Trial name
- NCT00967161
- Testing
- Total Knee Arthroplasty, Motion analysis
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Constipation
Mixed Natural Prebiotic-Fibers Impact on Stool Frequency and Fecal Microbiota in Constipated Thai Adults
Mixed Natural Prebiotic-Fibers Impact on Stool Frequency and Fecal Microbiota in Constipated Thai Adults: A Randomized Clinical Trial.
- Trial name
- NCT06274242
- Testing
- Haruna
- Where
- Thailand
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Retention Rate of Flowable Composite in Demenerlized Pits and Fissure
Retention Rate of Hydroxyapatite Nano-Fiber Reinforced Flowable Composite Versus Conventional
Pits and fissures have been considered as the single most important feature leading to the development of occlusal caries; About 90 % of carious lesions are found in the pits and fissures of permanent posterior teeth .Several…
- Trial name
- NCT03264105
- Testing
- Hydroxyapatite Nanofiber reinforced flowable composite, conventional resin-based flowable composite
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Cairo University
HIV Infections
Safety and Effectiveness of an HIV DNA Vaccine Followed by an HIV Adenoviral Vector Vaccine for Prevention of HIV Infection in the Americas and Africa
The development of a safe and effective vaccine is the best strategy for preventing the spread of HIV-1. The purpose of this study is to determine the safety and effectiveness of and immune responses to an HIV vaccine regimen in…
- Trial name
- NCT00498056
- Testing
- VRC-HIVDNA016-00-VP, VRC-HIVADV014-00-VP
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Tranexamic Acid Adverse Reaction
Tranexamic Acid in Sleeve Gastrectomy
The effectiveness of Tranexamic acid use will be measured in cases of sleeve gastrectomy in bariatric surgery and in early postoperative bleeding.
- Trial name
- NCT05696951
- Testing
- Transamine 200mg iv
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Halitosis
The Efficacy of Oregano Essential Oil in Reducing Oral Halitosis
the efficacy of commercially available oregano essential oil mouthwash in the reduction of oral halitosis was compared to chlorhexidine and distilled water and the results showed significant reduction of organoleptic tongue and…
- Trial name
- NCT04779502
- Testing
- oregawash, corsodyl
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- MOHAMED SAEED M. ALI
Gestational Diabetes, Diabetes Mellitus, Type 2
Decrease Type II Diabetes in Gestational Diabetes Population
The goal of the study is to examine the impact of an educational video on the rate of breastfeeding in mothers who had gestational diabetes mellitus, and the rate of type-II diabetes mellitus diagnosed postpartum.
- Conditions
- Gestational Diabetes, Diabetes Mellitus, Type 2, Breastfeeding, Diabetes Mellitus, Type 1
- Trial name
- NCT05202002
- Testing
- Video clip, No video clip
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Resorption of Tooth or Root
Clinical & Radiographic Evaluation of LSTR in Non-vital Primary Molars Using Two Different Vehicles
LSTR will be done for primary teeth with significant root resorption needing non-vital pulp therapy to save such teeth for up to 12 months.
- Trial name
- LSTR (NCT05079802)
- Testing
- Double antibiotic paste mixed with chitosan nanoparticles, Double antibiotic paste mixed with propylene glycol
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Endometriosis, Microbiome Dysbiosis
Trial Evaluating Nutritional Fiber in Digestive Symptoms of Endometriosis
This study is a double-blind, randomized, placebo-controlled study that evaluates the safety and tolerability of a fiber-based dietary supplement and the mechanistic and structure-function effects of that supplement on the gut…
- Conditions
- Endometriosis, Microbiome Dysbiosis, Gastrointestinal Symptoms
- Trial name
- TEND (NCT07875062)
- Testing
- Fiber
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- LOAM Science
Cesarean Delivery Procedures
Randomized Controlled Trial of Bladder Flap vs.None
Objective: To compare outcomes in cesarean section patients undergoing bladder flap versus none. Hypotheses: Operative time will be reduced with the elimination of a bladder flap during cesarean delivery and intra-operative and…
- Trial name
- NCT00470288
- Testing
- bladder flap during cesarean section
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Mountain Area Health Organization Center
Adolescent Behavior
Effects of Self-efficacy, Planning, and Self-efficacy+Planning Interventions on Body Fat Among Adolescents
This longitudinal experimental study tested the effects of three brief interventions: (1) prompting the formation of plans (or implementation intentions), (2) prompting self-efficacy beliefs, and (3) prompting planning +…
- Trial name
- NCT02689973
- Testing
- Self-Efficacy, Planning, Education
- Where
- Poland
- Volunteers
- 1,217 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Joint Function Disorder
Efficacy of a Dietary Ingredient Combination With Omega-3 for Joint Function
Randomized, controlled, double-blind intervention study of four parallel branches depending on the product consumed, to analyze the efficacy of an Omega-3 based product on the mobility and functionality of the evaluated joint.
- Trial name
- 7DHA (NCT05279573)
- Testing
- Omega-3 and/or botanical ingredient, Control product consumption
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Recurrent/Metastatic Breast Cancer
Clinical Trial for Effect of TQB3616 Capsule on Pharmacokinetics in Healthy Adult Subjects
TQB3616 capsule is a small molecule oral drug developed by Chia Tai Tianqing Pharmaceutical Group Co., Ltd., which inhibits cyclin-dependent kinases 4 and 6 (CDK4/6).
- Trial name
- NCT05344729
- Testing
- TQB3616 Capsule
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Deprescription, Antidepressants
Deprescription of Antidepressants in Primary Care (DAPriCare)
Introduction The consumption of antidepressants has increased considerably worldwide, including in Spain. Despite their effectiveness in cases of moderate to severe depression, their long-term use in mild cases is questioned.
- Trial name
- DAPriCare (NCT06796946)
- Testing
- Deprescription of Antidepressants (fluoxetine, citalopram, sertraline, paroxetine, and escitalopram)
- Where
- Spain
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- University of Huelva
Attention Deficit Hyperactivity Disorder
Efficacy of the Nurtured Heart Approach to Reduce ADHD Behaviors in Children
This study evaluates the efficacy of the Nurtured Heart Approach (NHA) to reduce inattention and hyperactivity and impulsivity in children ages 6 - 8 years.
- Trial name
- NCT03685279
- Testing
- Nurtured Heart Approach
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Arizona
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