Clinical trials: Randomized Clinical Trial
Leiomyoma, Uterine, Intraoperative Blood Loss
Intravenous Tranexamic Acid and Intramyometrial Desmopressin Effect on Blood Loss During Laparoscopic Myomectomy.
To evaluate the effect of intravenous tranexamic acid plus intramyometrial desmopressin administration on perioperative blood loss and blood transfusion need in laparoscopic myomectomy operation.
- Trial name
- NCT05517590
- Testing
- Tranexamic acid, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Hearing Impairment
The Beneficial Effects of Pomegranate on Hearing of Patients Without Hemodialysis
Pomegranate has anti-oxidative capacity. It might reduce symptoms of Alzheimer's disease, Drug-induced hepatitis, and might prevent deterioration of cardiovascular diseases and cancer progression.
- Trial name
- NCT03575390
- Testing
- Pomegranate
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Nasopharyngeal Carcinoma (NPC)
Individualized Neck Cervical Irradiation Prophylaxis Trial of NPC
Based on the pattern of nasopharyngeal carcinoma cervical lymph node metastasis, which typically follows a sequential downward spread with rare skip metastases and a tendency for ipsilateral neck involvement, and in accordance…
- Trial name
- INCIPT-NPC (NCT07303023)
- Testing
- Individualized Neck Irradiation, Standard Neck Irradiation
- Where
- 6 sites in China
- Volunteers
- 462 people, healthy volunteers welcome
- Sponsor
- Fudan University
Pulmonary Tuberculosis
Phase 1 ID93 + GLA-SE Vaccine Trial in BCG-Vaccinated Healthy Adult Volunteers
The purpose of this study is to determine the safety, tolerability, and immunogenicity in BCG-vaccinated healthy adult subjects of an investigational vaccine being developed for the prevention of pulmonary tuberculosis.
- Trial name
- NCT01927159
- Testing
- ID93 + GLA-SE
- Where
- South Africa
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Access to Advanced Health Institute (AAHI)
Healthy
Single Ascending Dose PK, Oral Bioavailability and Food Effect Study in Healthy Male Volunteers
This 2-part study will assess the effect of formulation and food on the pharmacokinetics of Indoximod in healthy volunteers. Part 1 is a randomized single ascending dose study of indoximod salt formulation to characterize the PK…
- Trial name
- NLG2111 (NCT03852446)
- Testing
- Indoximod HCL (F2) tablets, Indoximod base formulation
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- NewLink Genetics Corporation
Soccer Performance
Combined Technical and Balance Training in U12 Soccer Players
This study was designed as a two-arm, parallel-group randomized controlled trial to investigate the effects of a combined technical and balance training program on dynamic postural control, inter-limb asymmetry, and…
- Trial name
- NCT07853638
- Testing
- Combined technical and unstable-surface balance training
- Where
- Tunisia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manouba
Prediabetic State
Effectiveness of a Nurse-led Personalized Telephone Intervention on Lifestyle Changes in Diabetes Prevention.
A randomized, 9-months, parallel-group study comparing the effectiveness of a nurse-led telephone personalized lifestyle intervention versus automated SMSs on nutritional and physical activity advice in the reduction of fasting…
- Trial name
- PREDIPHONE (NCT04735640)
- Testing
- nurse-led teleconsultation, SMS
- Where
- Spain
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Covid19
COVID-19 Project ECHO in Nursing Homes
Nursing homes are ground zero for the COVID-19 pandemic. Nursing homes are ill-equipped for the pandemic; though facilities are required to have infection control staff, only 3% have taken a basic infection control course.
- Trial name
- NCT04499391
- Testing
- Project ECHO
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Childhood Obesity
Efficacy of an Educational School-based Intervention to Reduce Prevalence of Obesity in Childhood-EdAl-2
Our hypothesis is that a regular systematic educational intervention in primary school improves lifestyle choices and reduces obesity.
- Trial name
- EDAL2 (NCT01362023)
- Testing
- lifestyle counseling
- Where
- Spain
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Episiotomy
THE EFFECT OF STAPLER VERSUS SKIN SUTURING ON PAIN AND WOUND HEALING AFTER EPISIOTOMY REPAIR IN PRIMIPAROUS WOMEN
This randomized controlled study aims to evaluate the effects of skin closure using surgical staplers compared with conventional skin sutures on postoperative pain and wound healing in primiparous women undergoing episiotomy…
- Trial name
- NCT07383623
- Testing
- stapler skin closure, absorbable suture group
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ayşegül Kanık
Potential Abnormality of Glucose Tolerance, Appetitive Behavior
Acute Effects of Cookies Containing 2.5 g Spirulina on Postprandial Glycemic and Insulin Responses
This study investigated the effects of cookies containing 2.5 g Spirulina on postprandial glycemic and insulin responses.
- Conditions
- Potential Abnormality of Glucose Tolerance, Appetitive Behavior, Blood Pressure
- Trial name
- NCT05484323
- Testing
- Glucose as reference food, White bread, Cookie containing 0 g spirulina
- Where
- Greece
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Insomnia, Randomised Controlled Trial
Buddhist Awareness Training Program and Qigong Psychosocial Interventions for People With Insomnia
This study aims to compare the efficacy of the Mahayana Buddhist Awareness Training Program (ATP) with a Qigong group in treating people with insomnia in Hong Kong.
- Trial name
- NCT06910423
- Testing
- Psychosocial intervention
- Where
- Hong Kong
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- College of Professional and Continuing Education Limited
Acute Stress Disorder, Anxiety
GASA-CIR Trail (Guidance and the Symptoms of Acute Stress and Anxiety in Critically Ill Patients Relatives in Intensive Care Unit)
A randomized clinical trial 1:1 among relatives of patients admitted to an intensive care unit, the intervention group will be composed by family members who receive a printed brochure and will be encouraged to visit a website…
- Conditions
- Acute Stress Disorder, Anxiety, Depression
- Trial name
- GASA-CIR (NCT03812458)
- Testing
- website and brochure
- Where
- Brazil
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Cerebral Palsy
"Comparing the Plaque Removal Ability of Two Different Toothbrushes Among School Going CP Children
It was an intervention utilizing two toothbrushes on school going cerebral palsy children age (6 -18 yrs). The triple head tooth brush and single head brush was provided to parents along with dental health education to their…
- Trial name
- NCT05536648
- Testing
- Comparing the plaque removal ability of triple head tooth brush versus single head tooth brush among school based cerebral palsy children: A Randomized Control Trial
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Gingival Recession
Low-intensity Laser Therapy in the Treatment of Gingival Recession
The purpose of this study was to evaluate the 6-month outcomes of applying low-intensity laser therapy associated with connective tissue grafts to treat gingival recession.
- Trial name
- LILT (NCT02118155)
- Testing
- Connective tissue graft
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Healthy
A Multiple Dose Study of DWP10292 and UDCA in Healthy Male Subjects
The purpose of this study is to evaluate safety, tolerability, pharmacokinetics and pharmacodynamics of DWP10292 and UDCA in healthy male volunteers after multiple-dosing.
- Trial name
- NCT02622685
- Testing
- DWP10292, Ursodeoxycholic acid (UDCA)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Tuberculosis
Impact Evaluation of Use of MATCH AI Predictive Modelling for Identification of Hotspots for TB Active Case Finding
The aim of this pragmatic, stepped wedge cluster-randomized trial is to measure the comparative yield (number of incident TB cases diagnosed during active case-finding camps) using a site selection approach based on predictions…
- Trial name
- SPOT-TB (NCT06017843)
- Testing
- Camps site selection for active case finding for TB using MATCH-AI
- Where
- Pakistan
- Volunteers
- 180,000 people, healthy volunteers welcome
- Sponsor
- Centre for Global Public Health Pakistan
Alveolar Bone Loss
Autogenous Demineralized Dentin Block Graft Versus Autogenous Bone Block Graft for Alveolar Ridge Preservation
The aim of this trial is to compare the effect of autogenous demineralized dentin block graft (ADDBG) versus autogenous bone block graft (ABBG) harvested from maxillary tuberosity on alveolar ridge preservation after extraction…
- Trial name
- NCT05347017
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin block graft, Alveolar ridge preservation using autogenous bone block graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anxiety, Pain
Text Message Study
The objectives of this double-blind, randomized, controlled study are to evaluate the efficacy of maintaining contact with low-back pain patients through text messaging and emailing, to decrease anxiety levels, pain, number of…
- Conditions
- Anxiety, Pain, Surgical Site Infection
- Trial name
- NCT01789697
- Testing
- cellular device/computers
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
Sleep Disorders
Clinical Trial of the Safety and Tolerability of the Drug MMH-450 in Healthy Volunteers
Open-label, non-comparative, non-randomized clinical trial of the safety and tolerability of the drug MMH-450 in healthy volunteers
- Trial name
- NCT07708623
- Testing
- MMH-450
- Where
- Russia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Materia Medica Holding
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