Clinical trials: Randomized Controlled Trial (RCT)
Sleep, Healthy
Investigating the Efficacy of Rest-ZZZ Formula in Healthy Participants With Difficulty Falling Asleep or Staying a Sleep
A randomized, double-blind, placebo-controlled, cross-over pilot study to investigate the efficacy of Rest-ZZZ in healthy participants with difficulty falling asleep or staying a sleep. The study will have 3 study periods.
- Trial name
- NCT04093271
- Testing
- Rest-ZZZ, Active Comparator - Diphenhydramine HCl
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- LifeSeasons Inc.
Periodontitis
Assessment the Efficacy of Curcumin Local Delivery Gel in Treatment of Periodontitis in Smokers
Smokers usually respond less favourably to non-surgical periodontal treatment compared to non-smokers. Numerous studies reported that smoker patients exhibited less reduction in probing depth and less gains in clinical attachment…
- Trial name
- NCT06653231
- Testing
- local delivery of Curcumin gel
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Posttraumatic Stress Disorder, Depression
Evaluation of a MCYI as Adjunct to Psychiatric Treatment for Vietnam Veterans With PTSD - RCT
The principal aim of this project is to conduct a Randomized Controlled Trial (RCT) to examine whether adding a twelve-session Multi-Component Yoga Intervention (MCYI) to the treatment regimen of Australian Vietnam Veterans…
- Trial name
- NCT00256464
- Testing
- Multi-component Yoga Intervention
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Stress, Burnout
RISE RCT for Nurse Leaders
The purpose of this study is to determine whether RISE for Nurse Leaders has a significant impact on nurse leaders' post-traumatic growth, resilience, insight, self-compassion, and empowerment, as well as mental well-being, in…
- Trial name
- RISE (NCT05254600)
- Testing
- RISE for Nurse Leaders Program
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Critical Illness, Stress
Effects of a Psycho-cognitive Nursing Intervention on Patients' Outcomes in Critical Illness
The purpose of this study is to investigate whether a psycho-cognitive nursing intervention including relaxation, guided imagery, touch and music listening can improve the clinical and psychological outcome of critically ill…
- Conditions
- Critical Illness, Stress, Inflammatory Response
- Trial name
- NCT02423252
- Testing
- Massage, Relaxation, Guided imagery and music listening., No Intervention
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr Elizabeth Papathanassoglou
Multiple Sclerosis
A RCT of Telephone-supported ACT in MS
This study will investigate the feasibility of running a randomised controlled trial (RCT) of a psychotherapy called "Acceptance and Commitment Therapy (ACT)", delivered in a self-help format with additional telephone support…
- Trial name
- NCT02596633
- Testing
- Telephone-support Acceptance and Commitment Therapy (ACT)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Transgender, Health Attitude
Transgender Health: an Educational RCT
The investigators will conduct a randomized controlled trial (RCT) comparing two different educational approaches on the healthcare of transgender and gender expansive (TGE) youth.
- Trial name
- NCT05080335
- Testing
- Short videos
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yale University
Cognitive Decline, Cognitive Impairment, Mild
Effects of Multimodal Training of Combined Cognitive and/or Physical Training on Cognition and Fitness of Older Adults
The elderly population worldwide is expected to increase exponentially. There will be a higher percentage of older adults suffering cognitive decline in the coming decades.
- Trial name
- MTCCP (NCT04727450)
- Testing
- Cognitive training, physical training, Combination of cognitive and physical training (CCPT)-BIGMAP
- Where
- Hong Kong
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
"Forest Therapy and Mindfulness for Stress Reduction and Well-being in Highly Sensitive Persons (Pilot RCT)"
This study aims to evaluate the effects of Shinrin-Yoku (Forest Bathing) and Forest Medicine interventions on psychological well-being, stress reduction, and overall health outcomes in adults.
- Trial name
- HSP-FOREST (NCT07183917)
- Testing
- Forest Therapy and Mindfulness, Indoor Wellness Control
- Where
- Spain
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- IFM International Forest Medicine
Menstrual Health Intervention, Product Use Issue
An MHH Intervention in Bangladesh Health Systems
Over 50% of Bangladeshi women and girls use old cloths as menstrual absorbents due to cost, comfort, and familiarity. A substantial proportion, comprising 52% of adolescent girls and 62% of women washed the cloths with soap and…
- Conditions
- Menstrual Health Intervention, Product Use Issue, Hygiene Practices and Knowledge, Menstrual Hygiene Management
- Trial name
- NCT07723885
- Testing
- Menstrual health and hygiene intervention
- Where
- Bangladesh
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Gonorrhea Male, Chlamydia;M
Pay-it-forward RCT for Gonorrhea and Chlamydia Testing
This is a randomized controlled trial which will evaluate dual gonorrhea/chlamydia test uptake and other outcomes in men who have sex with men (MSM) in three trial arms - 1) a pay-it-forward testing arm, 2) a pay-what-you-want…
- Trial name
- NCT03741725
- Testing
- Pay-it-forward, Pay-what-you-want
- Where
- 3 sites in China
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Overweight
HealthyTogether: RCT of a Dyadic Weight Management Intervention
Four in five Veterans have overweight or obesity. However, few eligible Veterans achieve meaningful weight loss in VA's national MOVE! Weight Management Program.
- Trial name
- NCT06619041
- Testing
- HealthyTogether
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Yoga-Based Recovery Course, Control
ED Recovery Course Online RCT
The purpose of this study is to examine whether the Eat Breathe Thrive (EBT) Yoga for Eating Disorder Recovery online course is effective in supporting eating disorder recovery.
- Trial name
- NCT04557566
- Testing
- EBT yoga-based eating disorder course
- Where
- United States
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Healthy, Psychological Distress
The Effects of the Somatic Intervention 'Dance-Walk' on Body Awareness, Vitality, and Mental Health in Help-Seeking Adults: a RCT Study
The goal of this clinical trial is to learn if a movement program called "Dance-Walk" can improve body awareness, energy levels, and mental health in adults seeking mental health support.
- Conditions
- Healthy, Psychological Distress, Stress, Depression Disorders
- Trial name
- DANCEWALK (NCT07024901)
- Testing
- Dance-walk
- Where
- Lithuania
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Relapse, Gingival Recession
RCT for the Effectiveness of 3 Orthodontic Retention Schemes on Post-treatment Stability and Gingival Recession
The present study aims to assess the effectiveness of three different retention schemes used to maintain tooth position after orthodontic treatment with fixed orthodontic appliances (stability) and to evaluate possible…
- Trial name
- OrthRe10tion (NCT02742493)
- Testing
- 0.028 bonded to canines, 0.027 7-strand bonded to all 6, removable Hawley-type
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Athens
Physical Activity, Academic Achievement
The Effect of Increased Physical Activity on Adolescents' Health and Academic Performance: The School in Motion Study
This study evaluates the effect of 120 minutes extra of physical education (PE) or physical activity (PA) on adolescents' physical health, mental health, academic performance and learning environment.
- Conditions
- Physical Activity, Academic Achievement, Mental Health
- Trial name
- ScIM (NCT03817047)
- Testing
- Physical education, Physical active learning, Physical activity
- Where
- Norway
- Volunteers
- 2,045 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Hysterectomy
RCT Superior Hypogastric Block During LH
The goal of this study is to assess the efficacy of a superior hypogastric plexus block (SHPB) for pain relief following a laparoscopic hysterectomy.
- Trial name
- NCT03283436
- Testing
- Bupivacaine Hydrochloride 0.25% Injection Solution
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jon I. Einarsson
Social Support, Affect
Development & Pilot RCT of an Online Peer Support Program for Family Caregivers of Ventilator-Assisted Individuals
Ventilator assisted individuals (VAIs) living at home are frail and generally cannot perform most daily activities. Although these individuals prefer to live at home, the family members who care for them often experience stress…
- Conditions
- Social Support, Affect, Ventilators, Mechanical
- Trial name
- NCT03376711
- Testing
- Online Peer Support Program
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Contraception
RCT: Can a Single Counseling Phone Call Improve Contraception After an Abortion?
Hypothesis: Use of an effective contraceptive six weeks after abortion will be higher in the treatment group than in the control group.
- Trial name
- PPR (NCT01199952)
- Testing
- Treatment group: receives counseling phone call intervention
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV
A Pilot Trial of an Individualized Web-Based Condom Use Intervention
The purpose of this study is to evaluate the efficacy of an online intervention in increasing condom use among HIV+ gay males.
- Trial name
- NCT01726153
- Testing
- Condom-HIM
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)