Clinical trials: Randomized-controlled Trial
Procedural Pain
Analgesic Effect of Low Level Laser for Procedural Pain in Newborn Infants
Neonates undergo several painful procedures and these pain experiences can alter clinical outcome and behavior. The investigators aim to investigate the analgesic effect of low level laser for procedural pain during heel lancing…
- Trial name
- NCT03268148
- Testing
- LaserPen
- Where
- Taiwan
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Learning Curves and Outcomes of Simulation-based Training
Is Two-on-one Instruction in Virtual Reality Simulation-based Training of Operating Fractures of the Hip for Medical Students as Effective as One-on-one Instruction
The training of orthopedic surgeons has historically relied heavily on an apprenticeship model as the primary way of teaching the various procedures an aspiring surgeon needs to master.
- Trial name
- NCT06612619
- Testing
- Dyad instruction
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Immediate Implant
Evaluation of Cross-linked Collagen Membrane With and Without Silk Fibroin Around Immediate Dental Implants
Comparative evaluation of cross-linked collagen membrane with and without silk fibroin around Immediate Dental Implants -Randomized controlled trial.
- Trial name
- NCT06552065
- Testing
- collagen with silk fibroin membrane, cross linked collagen membrane
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Emotion Regulation, Parent-Child Relations
Improving Emotional Regulation Skills of Children in Difficulty in Shenzhen
The study aims to 1) improve the emotional regulation strategies of children in difficulty in Shenzhen, and 2) develop and publish a set of evidence-based intervention manuals for professional use.
- Conditions
- Emotion Regulation, Parent-Child Relations, Happiness, Positive Affect
- Trial name
- NCT06331936
- Testing
- Emotion regulation
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Physical Activity
Behavioral Economics Framingham Incentive Trial (BE FIT)
BE FIT (Behavioral Economics Framingham Incentive Trial) is a pilot study to test the deployment of a social incentive intervention using the Framingham Heart Study (FHS) Offspring, Generation 3, and Omni cohorts to increase…
- Trial name
- BEFIT (NCT02531763)
- Testing
- Social incentive intervention
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Clinical Reasoning, Orotracheal Suctioning
Animation-Based Orotracheal Suction Training for Expert Nurses
This randomized controlled trial aimed to evaluate the effect of animation-based orotracheal suction training on the clinical reasoning competency and knowledge levels of expert pediatric nurses.
- Conditions
- Clinical Reasoning, Orotracheal Suctioning, Nursing Education
- Trial name
- ABOST-EN (NCT07688993)
- Testing
- Animation-Based Orotracheal Suction Training, PowerPoint-Supported Traditional Training
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Radiography, Dentistry
Can a Digital Education Program in Radiographic Imaging Technique for Dental Professionals Improve Image Quality?
The goal of this clinical trial is to learn if a digital education program designed for dental professionals can lead to radiographic examinations of better quality.
- Trial name
- NCT06442904
- Testing
- Digital education program
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Umeå University
Fibromyalgia
Understanding and Restoring Dopaminergic Function in Fibromyalgia Patients
Fibromyalgia (FM) is a very prevalent and debilitating chronic pain disorder that is difficult to treat. Mindfulness-based techniques are regarded as a very promising approach for the treatment of chronic pain and in particular…
- Trial name
- FIBRODOPA (NCT04451564)
- Testing
- Mindfulness oriented recovery enhancement
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Anxiety, Stress
Cluster-randomized Controlled Trial of Mindfulness-Based Cognitive Therapy Effects on Anxiety and Stress
To understand the potential effectiveness of a 4 week Mindfulness-Based Cognitive Therapy intervention delivered using a smartphone application for reducing anxiety and stress within college students.
- Trial name
- NCT06019299
- Testing
- Mindfulness Practice
- Where
- United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Vitamin D Deficiency
Topical Delivery of Vitamin D3 as Vitamin D Supplementation
After obtaining the approval from the IRB of University of Dammam and informed consent from 550 healthy patients, with vitamin D deficiency and vitamin D insufficiency and deficiency were recruited.
- Trial name
- NCT02735200
- Testing
- Application of topical vitamin d3 (Top-D), Application of Aloe vera gel
- Where
- Saudi Arabia
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Adjustable Headrests, Ventilation Function
A Study on Application of Adjustable Headrest in Painless Curettage Surgery for Overweight and Obese Patients
The aim of this study is to observe the effect of adjustable headrests on ventilation function in overweight and obese patients through clinical experiments, and to explore the impact on the incidence of hypoxemia during painless…
- Conditions
- Adjustable Headrests, Ventilation Function, Obese Patients
- Trial name
- NCT06929000
- Testing
- the supine head-lateral position group, the adjustable headrest group, the supine head-straight position group
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Anxiety, Chest Tube Removal
Virtual Reality-Based Breathing Yoga Before Chest Tube Removal After Cardiac Surgery
This randomized controlled trial was conducted to evaluate the effect of virtual reality-based breathing yoga applied before chest tube removal on pain and anxiety in patients after cardiac surgery.
- Conditions
- Anxiety, Chest Tube Removal, Pain After Surgery
- Trial name
- NCT07794709
- Testing
- Virtual Reality-Based Breathing Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sennur Kula Şahin
Peri Implantitis
a Randomized Clinical Trial Evaluating Plaque Removal Around Dental Implants
This aim of this study is to compare different oral hygiene aids for the ability to remove plaque in patients who went through dental implant treatment and are currently on a maintenance program at the Graduate Periodontal…
- Trial name
- NCT02091609
- Testing
- dental interproximal brush, dental floss
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Virtual Reality, Surgical Training
The Role of Virtual Reality in Orthopaedic Surgery Education
Virtual reality (VR) and augmented reality are becoming prominent in the medical sciences due to the increasing sophistication of VR technology and its improving haptics to simulate real-life situations.
- Trial name
- NCT04302298
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Periodontal Diseases
Adjunctive Local Sodium Hypochlorite Gel in Non Surgical Periodontal Debridement
The aim of this study was to assess the efficacy of minimally invasive nonsurgical debridement (MINSD) of periodontal pockets with or without local amino acid buffered sodium hypochlorite (NaOCl) gel application after 6 months…
- Trial name
- NCT04399187
- Testing
- Sodium hypochlorite gel application
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Messina
Endodontically Treated Teeth, Endodontic Underfill
No Code Artificial Intelligence to Detect Radiographic Features Associated With Unsatisfactory Endodontic Treatment
Developing neural network-based models for image analysis can be time-consuming, requiring dataset design and model training. No-code AI platforms allow users to annotate object features without coding.
- Conditions
- Endodontically Treated Teeth, Endodontic Underfill, Endodontic Overfill, Apical Periodontitis
- Trial name
- NCT06450938
- Testing
- AI guidance for finding radiographic features
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Anxiety Disorders and Symptoms, Depressive Symptoms
Indicated Prevention Transdiagnostic Intervention for Adolescents At High Risk of Emotional Problems
Emotional disorders (anxiety and/or depression) are severely undiagnosed and untreated despite being among the most common mental disorders, particularly at a young age.
- Trial name
- PROCARE-I (NCT05252026)
- Testing
- PROCARE-I (UP-A for indicated purposes), Active control condition
- Where
- 3 sites in Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Pits and Fissure Sealants
A Comparative Evaluation of the Role of Self-Adhesive Flowable Composite in Enhancing Sealant Retention Versus Conventional Pits and Fissure Sealant With and Without Fissurotomy in Permanent Molars
This RCT study aims to establish evidence-based decision comparing between self-adhering flowable composite Vertise™ Flow (Kerr, Orange, CA, USA) and conventional resin-based pits \& fissure sealant Helioseal-F sealant (Ivoclar…
- Trial name
- NCT07399340
- Testing
- Self adhering flowable composite Vertise™ Flow (Kerr, Orange, CA, USA) with fissurotomy., Self adhering flowable composite Vertise™ Flow (Kerr, Orange, CA, USA) without fissurotomy., Conventional resin-based pits and fissure sealant Helioseal-F with fissurotomy.
- Where
- 2 sites in Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immediate Implant Placement
Immediate Implant Placement Using Xenograft Mixed with Vitamin D Versus Hyaluronic Acid.
Immediate implant placement using xenograft as space filling material mixed with vitamin D versus hyaluronic acid in posterior mandible region This study aims to evaluate implant stability and density after placement of immediate…
- Trial name
- NCT06842368
- Testing
- Hyaluronic Acid (HA), Vitamin D
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tobacco Smoking, Health Behavior
Recruitment Messages for Current Smokers Recently Diagnosed With Cancer
The objective of this study was to conduct a pilot factorial randomized trial to identify the message frames that are most effective in promoting participation in a tobacco treatment trial for current smokers recently diagnosed…
- Trial name
- NCT05471284
- Testing
- Proximal, Distal, Cost
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
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