Clinical trials: Randomized-controlled Trial
Depressive Symptoms, Nutrition, Healthy
Mind Nutrition Study. Effectiveness of Improving Nutrition on Depressive Symptoms and Work Ability
The goal of this randomized, controlled trial is to examine the effectiveness of dietary counseling on depressive symptoms, work ability, and quality of life in mental health and substance abuse professionals.
- Conditions
- Depressive Symptoms, Nutrition, Healthy, Quality of Life, Eating Behavior
- Trial name
- NCT06448117
- Testing
- Mind Nutrition
- Where
- Finland
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Satakunta University of Applied Sciences
HIV Infections
A Multicenter, Randomized, Placebo-Controlled, Double-Blinded, Phase I Trial to Evaluate the Safety and Immunogenicity of Live Recombinant Canarypox ALVAC-HIV vCP205 Combined With GM-CSF in Healthy, HIV-1 Uninfected Volunteers
To evaluate the safety and immunogenicity of live recombinant canarypox ALVAC-HIV vCP205 in combination with recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) at 80 microg and 250 microg.
- Trial name
- NCT00001090
- Testing
- APL 400-047, ALVAC-HIV MN120TMG (vCP205), Sargramostim
- Where
- 4 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Physical Inactivity, Frailty
The 'Outdoor Rehab-Fit' App-based Physical Activity Education Intervention for Frail Older Adults in Hong Kong
In recent years, research teams around the world have developed interventions to educate older adults to use outdoor exercise facilities (OEFs) to improve health outcomes like strength, balance, mobility, PA level, and weight.
- Trial name
- NCT06326710
- Testing
- mHealth, Health Talk
- Where
- Hong Kong
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myofascial Pain Syndrome
Evaluation of Pain Regression in Patients With Myofascial Facial Pain Using Dextrose, Local Anaesthesia and Saline.
The aim of this study is to compare the treatment effects of dextrose prolotherapy, saline, and mepivacaine for deactivating myofascial trigger points within the jaw muscles.
- Trial name
- NCT03161210
- Testing
- Dextrose Prolotherapy, Local Anaesthesia, Saline
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Colonoscopy, Colon Disease
Three Distraction Methods for Pain Reduction During Colonoscopy
Colonoscopy is a common procedure to evaluate the gastrointestinal tract. The colonoscopy procedure can sometimes be uncomfortable and painful for the patient.
- Trial name
- NCT05378165
- Testing
- Music group, Stress ball group, Video group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Vaccination, Reaction - Vaccine
To Evaluate the Immunogenicity and Safety of Sequential Immunization Schedules of Sabin IPV and bOPV
The purpose of this study is to evaluate the immunogenicity and safety of sequential immunization schedules of Sabin IPV and bOPV.
- Trial name
- NCT04054492
- Testing
- Sabin-IPV+bOPV+bOPV, Sabin-IPV+Sabin-IPV+bOPV, Sabin-IPV+Sabin-IPV+Sabin-IPV
- Where
- China
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Colorectal Cancer
Colorectal Cancer Screening Among Primary Care Physicians of the Swiss Sentinel Surveillance Network
Colorectal cancer (CRC) is the third leading cause of cancer mortality in Switzerland, and kills 1600 people annually. Most deaths could be prevented by screening, but the 2012 Swiss national health survey found that only 40% of…
- Trial name
- NCT03552744
- Testing
- Mailed training intervention
- Where
- Switzerland
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Bern
Labor Pain, Maternal Self-Efficacy
Stress Ball Intervention During Active Labor
This randomized controlled trial evaluates the effect of a stress ball intervention used during the active phase of labor primarily on maternal self-efficacy, while secondarily examining childbirth comfort, labor pain intensity…
- Conditions
- Labor Pain, Maternal Self-Efficacy, Childbirth Comfort
- Trial name
- NCT07451834
- Testing
- Stress Ball Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Monitored Anesthesia Care, Gastrointestinal Endoscopy
The Routine Use of Nasopharyngeal Airway in the Setting of Monitored Anesthesia Care During Gastrointestinal Endoscopy
The goal of this prospective, multi-center, single-blinded randomized controlled trial is to assess the efficacy of NPA in reducing respiratory events in patients being admitted for GI endoscopy (colonoscopy, gastroscopy…
- Conditions
- Monitored Anesthesia Care, Gastrointestinal Endoscopy, Nasopharyngeal Airway
- Trial name
- NCT04123821
- Testing
- Nasopharyngeal airway
- Where
- Lebanon
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Functional Abdominal Pain Syndrome
The Effects of Probiotics, Lactobacillus GG, in the Treatment of Abdominal Pain in Children With Functional Abdominal Pain Disorders
Recurrent or chronic abdominal pain is one of the common gastrointestinal problems in children. While most children do not have organic origins (so called functional abdominal pain disorders; FAPDs), the symptoms can nevertheless…
- Trial name
- NCT06310733
- Testing
- LGG
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Pediatric Disorder, Hypospadias
The Optimal Urethral Coverage in Hypospadias Repair: Dartos Fascia Versus Tunica Vaginalis Flap? A Randomized Controlled Trial
To explore the optimal urethral coverage in hypospadias repair by comparing the success rate of both covering techniques: Dartos fascia versus Tunica Vaginalis flap.
- Conditions
- Pediatric Disorder, Hypospadias, Congenital Hypospadia, Urologic Diseases
- Trial name
- NCT05123833
- Testing
- Hypospadias repair
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Adjunctive Usage of Vibrational Therapy, Dental Monitoring Accuracy
Optimizing Aligner Wear Time and Change Frequency
This study aims to help improve individualization and optimization of clear aligner therapy through the use of new technologies in orthodontics.
- Trial name
- NCT04260633
- Testing
- Dental Monitoring assisted aligner change, 12-hour tray wear time and VPro+ are the interventions for the trial.
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Renal Disease, Adherence, Treatment
The Effect of Motivational Interviewing and Education Based on Watson's Theory of Human Caring in Hemodialysis
Motivational interviewing and education based on Watson's Theory of Human Caring have an effect on increasing adherence to fluid intake in individuals receiving hemodialysis treatment.
- Conditions
- Renal Disease, Adherence, Treatment, Quality of Life, Satisfaction, Patient
- Trial name
- NCT04174638
- Testing
- Motivational Interviewing and Education Based on Watson's Theory of Human Caring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Contraception
Study of Immediate Start of Progestin Contraceptives in Medical Abortion
This study will compare immediate to post-abortion start of two progestin-based contraceptives (DMPA and etonorgestrel implants) among women having first trimester medical abortion who wish to use that method for post-abortion…
- Trial name
- Quickstart (NCT01902485)
- Testing
- Timing of Contraceptive Initiation in Medical Abortion
- Where
- 8 sites in United States, Mexico
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Plaque Psoriasis
Sequential Treatment of Psoriasis With Traditional Chinese and Western Medicine
The purpose of this study is to objectively and standardly evaluate the clinical efficacy and safety of sequential treatment of psoriasis with traditional Chinese and Western medicine through a multi-center, randomized…
- Trial name
- NCT05042635
- Testing
- Ixekizumab+Jueyin Granules
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Smoking
Impact of Graphic Cigarette Warnings
The purpose of this randomized controlled trial is to determine whether graphic health warnings on cigarette packs are more effective than the existing Surgeon General's warning on cigarette packs at encouraging quit attempts.
- Trial name
- NCT02247908
- Testing
- Surgeon General's Warning, Graphic Warning
- Where
- 2 sites in United States
- Volunteers
- 2,149 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Immune Mediated Inflammatory Diseases
A Trial to Learn How BAY1834845 and BAY1830839 Affect Inflammation When Taken by Mouth Twice a Day for 7 Days in a Row in Healthy Male Participants
The immune system helps protect the body from diseases. But, sometimes the immune system can be too sensitive and overreact to very small allergens, like dust and pet dander.
- Trial name
- NCT05003089
- Testing
- BAY1834845, BAY1830839, Prednisolone
- Where
- Netherlands
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Bayer
Adenoma, Colorectal Cancer
Combination of Artificial Intelligence and Mucosal Exposure Device to Enhance Colorectal Neoplasia Detection
The investigators hypothesize that the combined use of CADe system (ENDOAID) and mucosal exposure device (Endocuff Vision®) would improve the adenoma detection rate when compared to CADe system alone.
- Conditions
- Adenoma, Colorectal Cancer, Colorectal Neoplasms
- Trial name
- AIDEN (NCT05414448)
- Testing
- ENDOCUFF
- Where
- Hong Kong
- Volunteers
- 1,726 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Generalized Anxiety Disorder
The Comparative Clinical Study of Gamisoyosan on Anxiety of Generalized Anxiety Disorder According to Dosage Form
In this randomized, double blinded, Parallel-controlled study, the investigators planned to give Gamisoyosan extract, Gamisoyosan extract powder or controlled medication on Anxiety of generalized anxiety disorder according to…
- Trial name
- NCT01285115
- Testing
- KyungBangn-Gamisoyosan-x-gwarip, KyungBangn Gamisoyosan
- Where
- South Korea
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Korea Health Industry Development Institute
Botulism
Phase 3, Randomized, Safety, Lot Consistency and Clinical Benefit Study of Recombinant Botulinum Vaccine A/B
This Phase 3 clinical trial is a double blind, placebo-controlled, randomized, multicenter investigation of rBV A/B in male and female healthy adults 18 to 55 years of age.
- Trial name
- rBV A/B (NCT01940315)
- Testing
- rBV A/B
- Volunteers
- healthy volunteers welcome
- Sponsor
- DynPort Vaccine Company LLC, A GDIT Company
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