Clinical trials: Reaching
HIV-1-infection
Reversing the Epidemic in Africa With Choices in HIV Prevention (REACH)
Participants will be randomized (1:1) to one of two sequences of a vaginal ring (VR) containing 25mg of dapivirine to be inserted monthly for 24 weeks and 200 mg FTC/300 mg TDF oral tablets taken daily for 24 weeks.
- Trial name
- NCT03074786
- Testing
- Dapivirine, Truvada
- Where
- South Africa
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Fall
Effects of Balance Training on Fall Risk and Mobility in the Elderly
Pakistan is a country devoid of health-care facilities and training programs on fall prevention. There is lack of research, awareness and implication of geriatric rehabilitation on elderly population addressing balance and fall…
- Trial name
- NCT03656458
- Testing
- Warm Up, Conventional Balance Training, Biodex Balance Training
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Muscle Tightness
Effect of Manual Technique on Hamstring Flexibility
This study will be a randomized clinical trial. the study will be conducted in Mubarak Hospital Sargodha. a sample size of 44 subjects will be taken. subjects will be divided into two groups using the lottery method.
- Trial name
- NCT04967898
- Testing
- bowen technique, sustained stretching
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Childhood Obesity
Mountain West Prevention Research Center Core Research Project
This hybrid type 3 effectiveness-implementation sequential multiple assignment randomized trial will assess the impact of integrating population health management (PHM) strategies-text messaging and enrollment in Building Healthy…
- Trial name
- MW-PRCCRP (NCT07479498)
- Testing
- Text Message-based recruitment, Active outreach follow-up
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Paul Estabrooks
Communication, Bias, Racial
REACH Implicit Bias Training Project
The overall goal and theme of the Duke Center for Research to Advance Equity in Healthcare is to reduce racial and ethnic disparities in health through interventions that affect the clinical encounter.
- Conditions
- Communication, Bias, Racial, Relation, Doctor Patient
- Trial name
- NCT03415308
- Testing
- Focus Groups, Cognitive Interviews, Pilot Testing of Implicit Bias Training
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Duke University
Infant Development, Perinatal Stroke
Behavioral Assessment Method Index
The overall goal of this study is to develop and improve assessment methods for children with and without perinatal arterial ischemic stroke (PAS)/hemiparetic cerebral palsy (HCP).
- Conditions
- Infant Development, Perinatal Stroke, Hemiparesis, Cerebral Palsy
- Trial name
- BAM (NCT07291479)
- Testing
- Non interventional study
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Trachoma
Azithromycin Reduction to Reach Elimination of Trachoma
The investigators propose a randomized controlled trial of discontinuation versus continuation of annual mass azithromycin distribution in hypoendemic communities of Maradi, Niger.
- Trial name
- ARRET (NCT04185402)
- Testing
- Azithromycin
- Where
- Niger
- Volunteers
- 3,931 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV, Sexually Transmitted Diseases
Web-Based Middle School HIV Prevention Curricula: Aspiring for Reach and Impact
The purpose of this study is to evaluate the effectiveness of a web-based HIV, sexually transmitted infection (STI), and pregnancy prevention curriculum as a stand alone intervention for 8th grade students in a large urban school…
- Trial name
- NCT01280136
- Testing
- It's Your Game Tech
- Where
- United States
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pregnancy, Smoking Cessation
SmokefreeMOM: Reaching Pregnant Smokers With Health Information Via Text Messaging
Despite the great health benefits associated with smoking cessation in pregnancy to both mother and baby, few studies to date have examined the applications of text messaging or other communication technologies for smoking…
- Trial name
- SmokefreeMOM (NCT02412956)
- Testing
- SmokefreeMOM Text
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- George Washington University
Cancer
Galleri® in the Medicare Population.
This multi-center comparative prospective cohort study is designed to assess the real world clinical impact, including safety and test performance, of Galleri®, a blood-based multi-cancer early detection (MCED) test.
- Trial name
- NCT05673018
- Testing
- Multi-Cancer Early Detection Test (Galleri®)
- Where
- 72 sites in United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- GRAIL, Inc.
Trachoma
Azithromycin Reduction to Reach Elimination of Trachoma B
The investigators propose a randomized controlled trial of discontinuation versus continuation of annual mass azithromycin distribution in hypoendemic communities of Maniema, DRC.
- Trial name
- ARRET (NCT06289647)
- Testing
- Azithromycin
- Where
- Democratic Republic of the Congo
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obesity, Childhood
Expanding Health System Intervention Through The Women, Infants and Children (WIC) Program Partnership
Pilot test the health system-based intervention to improve family beverage choices and promote water consumption, engaging WIC nutritionists to augment the intervention with follow-up and counseling of families at…
- Trial name
- WHISPER (NCT05356338)
- Testing
- Pilot Intervention to reduce SSB consumption in children and families enrolled in WIC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cervical Cancer
Efficacy of Offering a Self-sampling Device by the GP to Reach Underscreened Women
The ESSAG trial invests the impact of offering a free self-sampling device (SSD) on the cervical cancer screening rate of underscreened women.
- Trial name
- ESSAG (NCT05656976)
- Testing
- Provision of self sampling device by the GP, Provision of self sampling device by letter
- Where
- Belgium
- Volunteers
- 3,375 people, healthy volunteers welcome
- Sponsor
- University Ghent
Smoking Cessation
Libre Del Cigarrillo: Development of an mHealth Smoking Cessation App to Extend Reach of a Validated Smoking Cessation Intervention for Spanish-speaking Smokers
Pilot randomized controlled trial evaluating feasibility, acceptability, and trial-readiness of the new app compared with the existing print booklets and the NCI SmokefreeTXT en Español program.
- Trial name
- NCT07754448
- Testing
- Libre del Cigarrillo Smartphone App, Libre del Cigarrillo Printed Booklets, SmokefreeTXT en Español
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Spinal Cord Injuries, Hand Weakness
Cognitive-based Prosthetics to Improve Grasp and Reaching After SCI
Rehabilitation of functional movements after spinal cord injury (SCI) requires commitment and engagement to the processes of physical therapy.
- Trial name
- NCT04577573
- Testing
- Cognition glove, Sensory brace
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Substance Use, Drug Use
Project REACH: A Comprehensive Telehealth Intervention at Syringe Service Programs to Engage People Who Use Drugs
This trial will assess the feasibility, acceptability, and preliminary effectiveness of Project REACH (Remote Engagement \& Access for Community Health), a telehealth intervention at syringe service programs (SSP) to improve…
- Trial name
- NCT07433712
- Testing
- Project REACH
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Depression, Suicide
Reaching Out to Distressed Medical Residents, Fellows and Faculty
The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and…
- Trial name
- NCT02010866
- Testing
- counseling
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Condomless Sex, Human Immunodeficiency Virus (HIV)
Cape Town Young Women's Health CoOp
This two-arm cluster randomized trial tested a gender-focused comprehensive HIV testing and counselling (HTC) program, the Young Women's Health CoOp (YWHC) with a standard HTC program and targeted female adolescents (aged 16-19)…
- Conditions
- Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infections (STIs), Alcohol and Drug Use
- Trial name
- NCT02974998
- Testing
- Young Women's Health CoOp (YWHC), Standard HTC
- Where
- South Africa
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RTI International
Saccadic Eye-Movement Exercise and Physical Performance, Physical Flexibility
Acute Effects of Saccadic Eye-Movement Exercise on Flexibility and Handgrip Strength
This randomized controlled trial investigated whether a short session of saccadic eye-movement exercises could produce immediate changes in flexibility and handgrip strength in healthy adults.
- Conditions
- Saccadic Eye-Movement Exercise and Physical Performance, Physical Flexibility, Handgrip Strength
- Trial name
- NCT07853521
- Testing
- Four-Phase Saccadic Eye-Movement Exercise Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
HIV Infections
The Test-to-PrEP Study
To compare the effectiveness of two social network strategies (direct distribution and referral-based distribution) in increasing HIV self-testing (HIVST) completion rates among social network contacts of current Pre-Exposure…
- Trial name
- NCT06927856
- Testing
- Test-to-PrEP, Access by Referral
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Miami