Clinical trials: Recurrent UTIs
Recurrent Urinary Tract Infection, Urinary Tract Infections
Preventing Recurrent UTI With Vaginal Estrogen
Among postmenopausal women who suffer from recurrent urinary tract infections (UTI), vaginal estrogen therapy prevents UTI recurrences for 50% of sufferers.
- Conditions
- Recurrent Urinary Tract Infection, Urinary Tract Infections, Cystitis Recurrent
- Trial name
- PRUVE (NCT05551949)
- Testing
- Vaginal estradiol tablets
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Johns Hopkins University
Urinary Tract Infection
Topical Steroids to Prevent Recurrent Urinary Tract Infections in Uncircumcised Male Infants: a Pilot Study
The goal of this smaller clinical trial is to evaluate the study design of this research to help prepare for a larger research study in the future.
- Trial name
- STRUMI-T (NCT07508124)
- Testing
- betamethasone valerate 0.1% cream
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Recurrent Urinary Tract Infection
Recurrent Urinary Tract Infections and the Microbiome
The primary objective is to determine if polymerase chain reaction (PCR) (UTIP™) is more sensitive in identifying urinary tract infections (UTI's) than standard urine cultures.
- Trial name
- NCT04831840
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Miami
Urinary Tract Infections (UTIs)
Evaluation of the Effectiveness and Safety of a Vaginal Gel for Prevention of Recurrent Urinary Tract Infections
Urinary Tract Infections (UTIs) are among the most common bacterial infections. Although they are typically treated effectively with antibiotics, recurrence is a frequent and troublesome issue.
- Trial name
- UTI (NCT07233473)
- Testing
- Multi-Gyn UT Protect gel
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Karo Pharma AB
Recurrent Urinary Tract Infections in Women
Evaluate the Efficacy and Safety of U101 Oral Capsules in the Prevention of Uncomplicated rUTIs in Women
The goal of this clinical trial is to learn if drug U101 works to prevent recurrent urinary tract infection (rUTI) in women (≥ 20 and < 76 years old) with a medical history.
- Trial name
- U101 (NCT07184827)
- Testing
- U101
- Where
- 18 sites in Taiwan
- Volunteers
- 348 people
- Sponsor
- TCM Biotech International Corp.
Urinary Incontinence, Overactive Bladder
Pain-perception During Outpatient cystoscopy-a Prospective Controlled Study
At an academic tertiary referral center, patients with pelvic floor dysfunction, scheduled for outpatient cystoscopy or urodynamic testing will be asked to participate in the study.
- Conditions
- Urinary Incontinence, Overactive Bladder, Pelvic Organ Prolapse, Recurrent Urinary Tract Infections
- Trial name
- NCT01663181
- Where
- Austria
- Volunteers
- 109 people
- Sponsor
- Medical University of Vienna
Urinary Tract Infections
Identification of Predictive Blood Biomarkers of Recurrent Urinary Tract Infections
Urinary tract infections affect more than 130 million people worldwide each year. Almost 50% of women will have at least one urinary tract infection during their lifetime, usually cystitis.
- Trial name
- Predict-UTI (NCT03819712)
- Testing
- Collection of blood samples, Collection of fecal samples, Collection of urine samples
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Recurrent Uti
Intravesical Gentamicin to Prevent Recurrent UTI
Feasibility assessment of intravesical gentamicin instillation (putting antibiotics directly into the bladder) versus the current standard of care of oral nitrofurantoin prophylaxis (taking a low dose of antibiotics by mouth…
- Trial name
- NCT06332781
- Testing
- Gentamicin, Nitrofurantoin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Urinary Tract Infection Chronic
Individualized Homeopathy to Reduce the Use of Antibiotics in Women With Recurrent Uncomplicated Urinary Tract Infections
The aim of the study is to determine the efficacy of individualised homeopathic drug treatment (potency C200 and C1000) compared to placebo in females (age 18<65) with recurrent urinary tract infections, per definition ≥ 2 UTI in…
- Trial name
- iHOM (NCT05545514)
- Testing
- One out of 140 predefined homeopathic medical products (HMP) in potency C200 or C1000,
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- Technical University of Munich
Periodontitis, Chronic Prostatitis (CP)
Periodontal Therapy and Genitourinary Inflammation in Patients With Prostatitis and Recurrent Urinary Tract Infections
This randomized controlled clinical trial evaluates the impact of non-surgical periodontal therapy on systemic inflammatory markers in patients with chronic prostatitis or recurrent urinary tract infections.
- Conditions
- Periodontitis, Chronic Prostatitis (CP), Urinary Tract Infections
- Trial name
- PERIO-PSA (NCT07438184)
- Testing
- Non-surgical periodontal therapy, Oral hygiene instruction
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Salamanca
Urinary Tract Infections
Fractional CO2 Vaginal LASER Therapy for Recurrent Urinary Tract Infection
Randomized controlled trial to determine clinical and microbiome difference between fractional CO2 Laser and vaginal estrogen in treating patients with recurrent urinary tract infection (UTI).
- Trial name
- NCT04301934
- Testing
- Mona Lisa Touch, Conjugated estrogen, Estradiol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Atrophic Vaginitis, Urinary Tract Infections
Hyaluronate for the Treatment and Prevention of Recurrent Urinary Tract Infection in Women Suffering Atrophic Vaginitis
In post-menopausal women, the condition atrophic vaginitis results from the loss of oestrogen and is characterised by dyspareunia (pain during intercourse), vaginal dryness, and vaginal irritation.
- Trial name
- HATPIN (NCT03981458)
- Testing
- Hyalofemme, Ialuril
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Uncomplicated Urinary Tract Infection, Patient With Uncomplicated UTI
Effectiveness of Visual Storytelling Intervention on Antibiotic Adherence in UTI Patients
This study aims to evaluate the effectiveness of a visual storytelling intervention in improving antibiotic adherence among adults with urinary tract infections (UTIs).
- Trial name
- ABR UTI (NCT06885658)
- Testing
- Visual Storytelling Intervention for Antibiotic Adherence
- Where
- Pakistan
- Volunteers
- 358 people
- Sponsor
- Xi'an Jiaotong University
Urinary Tract Infections
MV-140 Efficacy in Recurrent Urinary Tract Infections in a Cohort of Portuguese Adult Patients
We will access the efficacy of MV-140 immunotherapy in the prevention of recurrent urinary tract infections in a cohort of Portuguese patients.
- Trial name
- NCT06392282
- Testing
- MV-140
- Where
- Portugal
- Volunteers
- 104 people
- Sponsor
- Unidade Local de Saúde Santa Maria
Urinary Tract Infection (UTI)
Urell and Pregnancy
Evaluation of the effect of URELL consumption on the occurrence of recurrent urinary tract infection (Acute cystitis, pyelonephritis and asymptomatic bacteriuria).
- Trial name
- NCT01818180
- Testing
- URELL
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Hopital Foch
Recurrent Urinary Tract Infection, Safety Issues
Controlled Human Urine Transfusion for UTI
The primary objective of this pilot study is to investigate the safety and tolerability of controlled human urine transfusion in female patients with recurrent UTI's.
- Trial name
- SHUTUP (NCT03142295)
- Testing
- urine transfusion
- Where
- Netherlands
- Volunteers
- 6 people
- Sponsor
- Leiden University Medical Center
Urinary Tract Infections, Patients With Suprabubic Catheter
Study of E. Coli Isolates From Recurrent Urinary Tract Infections
Prospective study aiming at collecting clinical Escherichia coli isolates from patients with recurrent urinary tract infection; samples to be collected during routine procedures.
- Conditions
- Urinary Tract Infections, Patients With Suprabubic Catheter, Patients With Nephrostomy Catheter
- Trial name
- Per-UTI (NCT05826067)
- Testing
- collection of bacterial strains
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- Université Catholique de Louvain
Urinary Tract Infection
Usefulness of Antimicrobial Prophylaxis in Children With Isolated Vesico-Ureteral Reflux.
Randomized, prospective, multicenter study in order to assess the usefulness of antimicrobial prophylaxis in children with isolated vesico-ureteral reflux (grade III or less).
- Trial name
- NCT00200616
- Testing
- Antimicrobial prophylaxis
- Where
- France
- Volunteers
- 232 people
- Sponsor
- Nantes University Hospital
Recurrent Urinary Tract Infection, Genitourinary Syndrome of Menopause
RCT Comparing Intravaginal Laser Therapy to Sham in Post-menopausal Women with Recurrent Urinary Tract Infections
Recurrent urinary tract infection (rUTI) is a common and difficult to treat problem with limited treatment option; postmenopausal women are disproportionately affected.
- Trial name
- UTIEXTERMINATE (NCT06124820)
- Testing
- Deka SmartXide Touch C60 (MonaLisa Touch)
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- King's College Hospital NHS Trust
Urinary Tract Infection(UTI), Urinary Tract Infection, Recurrent
Multicentre Prospective Observational Cohort Study Aiming to Collect Medical Data, Create a Database to Facilitate Clinical and Fundamental Research Into Urinary Tract Infections With the Ultimate Goal of Improving Their Treatment.
The goal of this prospective observational study is to collect epidemiological, clinical, microbiological, genetic, and behavioral data on individuals with UTIs.
- Conditions
- Urinary Tract Infection(UTI), Urinary Tract Infection, Recurrent, UTI - Urinary Tract Infection
- Trial name
- IUTIC (NCT07485686)
- Where
- 5 sites in Germany, Netherlands and 1 more
- Volunteers
- 500 people
- Sponsor
- Angela HUTTNER