Clinical trials: Regression
Preoperative Anxiety
Comparing Virtual Reality (VR) to Non-VR for Decreasing Preoperative/Procedural Anxiety
The primary objective of the study is to utilize the modified Yale Preoperative Anxiety scale (mYPAS), a validated preoperative/procedural anxiety score, to measure preoperative anxiety via distraction in pediatric oncology…
- Trial name
- NCT05094141
- Testing
- Virtual reality
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Opioid Use
Does a Non-Opioid Multimodal Pain (NOMO) Protocol Decrease Narcotic Use
The objective of this study is to evaluate narcotic use after implementation of a Non-Opioid Multimodal Pain (NOMO) protocol in patients who are undergoing a urogynecologic procedure.
- Trial name
- NCT05386069
- Testing
- NOMO Protocol
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Hemiparesis
Improving Myoelectric Prosthetic and Orthotic Limb Control
The purpose of this study is to improve control of myoelectrically-controlled advanced orthotic devices (an exoskeleton device that use the body's muscle signals to drive movements of a robotic brace) by using advanced predictive…
- Trial name
- NCT05509101
- Testing
- commercially available control algorithm, experimental control algorithm
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Utah
Alzheimer's Disease, Dementia
Intervention Programs for Decreasing Caregiver Burden in Caregivers of Patients With Dementia
The purpose of this study is to investigate if behavioral intervention for dementia caregivers will decrease caregiver burden in caregivers of patients with dementia.
- Trial name
- I-care (NCT02397980)
- Testing
- Behavioral intervention
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University Mokdong Hospital
Loneliness, Opioid Use
Decreasing Loneliness to Optimize Pain Care
Loneliness, which is the perceived feeling of insufficient personal relationships, is related to higher risk for inappropriate opioid use and opioid use disorders in patients who are taking opioids long-term.
- Trial name
- DLoop (NCT06285032)
- Testing
- Cognitive Behavior Therapy (CBT), Social Navigation Group, Controlled Group
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Washington
Frailty
Effects of Community-center Based Dietary Intervention on Frailty Prevention and Regression in the Elderly.
Recent interventional studies have shown that frailty can be improved by modifying dietary quality. In this study, a set of nutrition-centric health promotion activities was developed in accordance with the Taiwanese Daily Food…
- Trial name
- NCT05129163
- Testing
- Exercise, Nutrition activities
- Where
- Taiwan
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Academia Sinica, Taiwan
Anesthesia, Pain
Decreasing the Invasiveness of Ultrasound Guided Caudal Block: A Comparison Between 22-gauge and 27-guage Needles
Ultrasound (US) has facilitated the use of caudal block in children and visualization of the needle during insertion. This prospective clinical trial study compares between two different sizes of the used needles, in terms of…
- Conditions
- Anesthesia, Pain, Caudal Block, Pediatric Anesthesia
- Trial name
- NCT04691531
- Testing
- The use of classical Gauge 22 needle, The use of classical Gauge 27 needle
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Pain, Post-operative Pain Control
Effect of Lidocaine in Reducing Opioids Requirement in Day Care Surgery
1. *Reduced opioid consumption 2. *Decreased pain scores 3. *Fewer opioid-related side effects 4. *Improved patient satisfaction
- Conditions
- Pain, Post-operative Pain Control, Post-operative Pain
- Trial name
- NCT06717672
- Testing
- Lidocaine 2% without vessel constrictor, Normal Saline
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Snoring
Pilot Study for Feasibility of Using an Oral Appliance for Decreasing Snoring
This research study proposes to determine how well tolerated and effective lower and upper oral dental devices are at reducing snoring.
- Trial name
- NCT04900285
- Testing
- Delta Dental Oral Device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Norton Healthcare
Vaccine Hesitancy, Communication
Emphasizing the Personal Versus the Social in Educational Interventions For Decreasing Vaccine Hesitancy
This experimental study aims to investigate the effect of different types of educational interventions on overcoming Coronavirus disease 2019 (COVID-19) vaccine hesitancy among the Higher School of Economics (HSE) bachelor…
- Trial name
- NCT05120817
- Testing
- "Personal" intervention, "Social" intervention, "Personal" + "Social" intervention
- Where
- Russia
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- National Research University Higher School of Economics
Cesarean Section Complications
Role of Drain in Decreasing Postoperative Complications
postoperative complications are common after cesarean section
- Trial name
- NCT04287933
- Testing
- Drain insertion
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Hypoxia, Erythropoiesis
Effects of Intermittent Hypoxia Training With Iron Supplementation on Red Blood Cells and Iron Levels in Trained Athletes
This study investigates how training under conditions of reduced oxygen (intermittent hypoxia) affects the body's ability to produce red blood cells and manage iron levels, compared to training under normal oxygen conditions.
- Conditions
- Hypoxia, Erythropoiesis, Iron Metabolism Disorders
- Trial name
- IHIT-IRON (NCT07720960)
- Testing
- Control group (CG), Hypoxia group (HG): trained at simulated altitudes between 4,450 and 5,850 m
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Néstor Vicente-Salar
Chronic Toxic Stress, Developmental/ Behavioral Regression in Young Children
(YMP) Young Moms Program
Young Moms Program (YMP) is designed to address systemic barriers to the health and stability of young moms and their children such as the lack of coordination of service delivery or logistical barriers within the health system.
- Trial name
- YMP (NCT05082857)
- Testing
- "traditional" Parents as Teachers (PAT), "hybrid" PAT model
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Stress, Relaxation
Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults
This study is a non-clinical substudy conducted within the DESTRESS research program (NCT05036538), which investigates the effects of relaxation interventions on physiological and psychological parameters.
- Conditions
- Stress, Relaxation, Virtual Reality, Binaural Beats
- Trial name
- DESTUD (NCT07387107)
- Testing
- Virtual Reality-Based Natural Environment, Binaural Auditory Stimulation, Control Condition (No Relaxation Intervention)
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Heart and Brain Research Group, Germany
ASD, GDD
Developmental Regression-related Disease Research and Achievement Transformation Innovation Team
The incidence rate of developmental regression is gradually increasing. In the early stages of children's development, both ASD and DD patients can experience developmental regression, which in turn aggravates cognitive function…
- Trial name
- NCT06155214
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chen Li
Chronic Postoperative Pain
Preoperative Erector Spinae Plane Block Versus Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome
Breast cancer is considered the commonest malignancy affecting women with an incidence exceeding one million cases per year. Although it has a favorable prognosis with improved lines of treatment, some complications may still…
- Trial name
- NCT06036979
- Testing
- Paravertebral plane block, Erector spinae plane block, Intravenous morphine, ketorlac and paracetamol
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Labor Pain, Pregnancy
The Association Between Decreasing Labor Analgesia Epidural Infusion and Forceps Delivery
The objective of this study will be to compare epidural infusion management, specifically looking at infusion rate changes, in patients who receive forceps deliveries versus normal spontaneous vaginal deliveries.
- Trial name
- NCT00443560
- Testing
- Case controlled analysis of epidural labor analgesia patterns
- Where
- United States
- Volunteers
- 2,162 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Infertility
Administration of Follicle-stimulating Hormone (FSH) and Low Dose Human Chorionic Gonadotropin (hCG) for Oocyte Maturity While Decreasing hCG Exposure in In Vitro Fertilization (IVF) Cycles
This is a randomized, double-blind, single center clinical trial study to compare oocyte competence and risk of ovarian hyperstimulation syndrome (OHSS) after receiving the standard dose of human chorionic gonadotropin (hCG)…
- Trial name
- NCT02310919
- Testing
- Low dose hCG plus FSH co-trigger, Standard dose of hCG
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anesthesia, General
Muscle Relaxants and Laryngeal Local Anesthetics for Laryngeal Mask Airway Insertion Decreasing Propofol in Elderly
Laryngeal mask airway (LMA) is currently the most widely used supraglottic airway device with advantages of simple and fast placement, reduced anesthesia drug use, more stable hemodynamics, and less throat discomfort after…
- Trial name
- LMA (NCT05310110)
- Testing
- 10% lidocaine spray, Cisatracurium, Propofol
- Where
- Taiwan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Post Operative Pain, Cesarean Section Pain
Application of Transversus Abdominus Plain Block, Local Subcutaneous Injection and IV Nalbuphine
Approximately 1 in 5 women who undergo CS will experience severe acute postoperative pain. The severity of pain in the acute postoperative period is a significant predictor for the development of chronic pain, which occurs in…
- Trial name
- NCT05276206
- Testing
- NSAID , NALUFIN , local anesthetic andTAP Block
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia