Clinical trials: Regression
Advanced Malignant Solid Neoplasm, C-Reactive Protein Measurement
Anamorelin Hydrochloride, Physical Activity, and Nutritional Counseling in Decreasing Cancer-Related Fatigue in Patients With Incurable Metastatic or Recurrent Solid Tumors
This phase II trial studies how well anamorelin hydrochloride, physical activity, and nutritional counseling work in decreasing cancer-related fatigue in patients with incurable solid tumors that have spread to other parts of the…
- Conditions
- Advanced Malignant Solid Neoplasm, C-Reactive Protein Measurement, Cancer Fatigue, Metastatic Malignant Solid Neoplasm
- Trial name
- NCT03035409
- Testing
- Anamorelin Hydrochloride, Exercise Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- M.D. Anderson Cancer Center
Pain, Postoperative, Pain, Acute
Sensory Assessment and Regression Rate of Bilateral External Oblique Intercostal Block and m-TAPA Block
External oblique and m-tapa blocks are routinely performed on patients undergoing laparoscopic cholecystectomy in our clinic. In this study, sensory block and regression rates will be investigated in patients who underwent block.
- Conditions
- Pain, Postoperative, Pain, Acute, Pain
- Trial name
- NCT05744544
- Testing
- External Oblique Block, m-TAPA block
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Samsun University
Bronchoscopy
This Study Will Evaluate the Effectiveness of a Simple Intervention Through a Classical Yankauer Oral Suction Tube, in Decreasing the Sedative Medication Doses Needed to Provide Effective Patient Sedation During Bronchoscopy, Along With Its Effect on Both Patient's and Bronchoscopist Satisfaction
The aim of this study is to evaluate the effectiveness of a simple intervention through a classical Yankauer oral suction tube, a device known to have a proven safety profile in multiple healthcare settings, in decreasing the…
- Trial name
- NCT06908109
- Testing
- Yankauer Suction Device, Bronchoscopy
- Volunteers
- 120 people
- Sponsor
- American University of Beirut Medical Center
Bleeding, Surgical Blood Loss
DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery
The aim is to conduct a double-dummy multi-centre randomized controlled clinical trial of application of topical dose of tranexamic acid (TxA) versus the usual intravenous TxA in patients undergoing on-pump cardiac surgery.
- Conditions
- Bleeding, Surgical Blood Loss, Seizures
- Trial name
- DEPOSITION (NCT03954314)
- Testing
- Tranexamic Acid
- Where
- 16 sites in Canada, China and 4 more
- Volunteers
- 3,242 people
- Sponsor
- Population Health Research Institute
Hypertrophic Cardiomyopathy
Study to Determine if Atorvastatin Reduces Size and Stiffness of Muscle in the Left Ventricle of the Heart
The purpose of this study is to determine if a drug called atorvastatin will reduce the size and stiffness of the muscle in the left ventricle of the heart.
- Trial name
- NCT00317967
- Testing
- Atorvastatin
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Calgary
Gastric Cancer (GC)
Beta-Blockers on Neoadjuvant Immunochemotherapy for Hypertensive Patients With Gastric Cancer
Study Population: Patients with locally advanced gastric cancer complicated by primary hypertension, who received neoadjuvant immunochemotherapy followed by curative gastrectomy at Nanfang Hospital of Southern Medical University…
- Trial name
- BNIHGC (NCT07622693)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Regression Equation, Teeth Measurement
Prediction of New Regression Equation Among a Group of Egyptian Children
Aim of the study: Prediction of new regression equation using digital analysis for determination of mesiodistal width of permanent teeth among a group of Egyptian children.
- Trial name
- NCT06753201
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Cairo University
SARS-CoV-2 Infection
Efficacy of ADW S-100 Ionized Water Nasal Spray in Decreasing SARS-Cov-2 Viral Load.
A nasal spray based on Advanced Water S-100 ionized water would clean the nasal cavity, reduce the viscosity of the mucus and facilitate its elimination and the decongestion of the nose and the prevention of the seizure of the…
- Trial name
- NCT05290987
- Testing
- nasal spray
- Where
- France
- Volunteers
- 13 people
- Sponsor
- P & B Group
Vaginal Misoprostol and Bilateral Uterine Artery Ligation in Decreasing Blood Loss in Trans-abdominal Myomectomy
Vaginal Misoprostol Versus Bilateral Uterine Artery Ligation in Decreasing Blood Loss in Trans-abdominal Myomectomy
The study aims at comparison between the effect of preoperative misoprostol and bilateral uterine artery ligation regarding their effect to decrease blood loss in transabdominal myomectomy.
- Trial name
- NCT02643186
- Testing
- preoperative vaginal misoprostol, bilateral uterine artery ligation
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Ain Shams Maternity Hospital
Chronic Kidney Disease stage3
Role of Activated Charcoal in Decreasing Blood Urea, Creatinine and Phosphorous
The study aims to explore the ability of Oral activated charcoal to adsorb uremic toxins limiting the progression of chronic kidney disease and delaying the need for hemodialysis in patients with CKD stages III and IV.
- Trial name
- NCT04311645
- Testing
- Activated charcoal, Dry seeds
- Volunteers
- 90 people
- Sponsor
- Assiut University
Abdominal Aortic Aneurysm Without Rupture
Pre-emptive Abdominal Aortic Aneurysm Sac Embolization During EVAR
Pre-emptive abdominal aortic aneurysm sac embolization during endovascular abdominal aortic repair for infrarenal abdominal aortic aneurysm - Randomized study
- Trial name
- NCT05575570
- Testing
- EVAR
- Volunteers
- 124 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cocaine Use Disorder
Efficacy of Repetitive Transcranial Magnetic Stimulation in Reducing Cocaine Intake in Addicted Patients
The study evaluates the efficacy of 3 weeks of repetitive transcranial magnetic stimulation (rTMS), 5 sessions/weekly, in reducing cocaine consumption immediately after and within the 8 weeks following the treatment in addicted…
- Trial name
- MagneTox (NCT03607591)
- Testing
- rTMS
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Proliferative Diabetic Retinopathy
Retrospective Review of Proliferative Diabetic Retinopathy Patients
The primary objective of the protocol is to determine if intravitreal ranibizumab alone decreases retinal neovascularization from Proliferative Diabetic Retinopathy (PDR) with deferred panretinal photocoagulation (PRP) and/or…
- Trial name
- NCT03609996
- Testing
- Panretinal Photocoagulation, Lucentis
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Elman Retina Group
Warfarin
Warfarin Dosage Adjustment Model Analysis Study
Despite the wide availability of Direct oral anticoagulation (DOAC), warfarin remains an important oral anticoagulant1 especially in patients with mechanical valve replacement or chronic renal failure where the evidence of DOAC…
- Trial name
- NCT05609500
- Testing
- Warfarin dosage adjustment model
- Where
- Hong Kong
- Volunteers
- 1,200 people
- Sponsor
- Chinese University of Hong Kong
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The Severity Assessment Model for AECOPD With Combination of Disease and Syndrome
The establishment of the AECOPD severity assessment model can quickly and accurately evaluate the condition, which is of great significance for standardizing diagnosis and treatment, improving efficacy, and improving prognosis.
- Trial name
- NCT06918353
- Testing
- Diagnosis and Severity Grading of AECOPD Disease
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Metastatic Melanoma, Metastatic Renal Cancer
Phase II Study of Aldesleukin (IL-2) Following the Administration of Zanolimumab (Anti-CD4mAb) in Metastatic Melanoma and Metastatic Renal Cancer
Background: Aldesleukin (IL-2) is a drug that can help to shrink tumors in some patients with metastatic renal cancer and metastatic melanoma.
- Trial name
- NCT01160445
- Testing
- Zanolimumab, Aldesleukin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Cancer Institute (NCI)
Gestational Diabetes, Diabetes Mellitus, Type 2
Decrease Type II Diabetes in Gestational Diabetes Population
The goal of the study is to examine the impact of an educational video on the rate of breastfeeding in mothers who had gestational diabetes mellitus, and the rate of type-II diabetes mellitus diagnosed postpartum.
- Conditions
- Gestational Diabetes, Diabetes Mellitus, Type 2, Breastfeeding, Diabetes Mellitus, Type 1
- Trial name
- NCT05202002
- Testing
- Video clip, No video clip
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Enhanced Recovery, Functional Endoscopic Sinus Surgery
Lidocaine Infusion Versus Magnesium Infusion in Decreasing Fentanyl Requirements in Endoscopic Sinus Surgeries
Enhanced recovery after ear, nose and throat surgery is based on multimodal and multidisciplinary perioperative interventions to decrease postoperative pain.
- Conditions
- Enhanced Recovery, Functional Endoscopic Sinus Surgery, Lidocaine, Magnesium Sulphate
- Trial name
- NCT06966102
- Testing
- Lidocaine group, Magnesium group, Control group
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Cairo University
Acute Pain
Comparison of Postoperative Outcomes Between Surgeries Anaesthetized With Propofol and Inhalational Anaesthetics
Propofol used as anaesthesia in surgery had shown small postoperative analgesic benefits over inhalational anaesthetics in some meta-analyses. It was also associated with reduced risk of postoperative nausea and vomiting.
- Trial name
- NCT03875872
- Testing
- Propofol, inhalation anaesthetics
- Where
- Hong Kong
- Volunteers
- 3,922 people
- Sponsor
- The University of Hong Kong
Bacteraemia Caused by Gram-Negative Bacteria
Antibiotic Durations for Gram-negative Bacteremia
Gram-negative bacteremia (GNB) is a frequent hospital \& community-acquired infection, yet there is as yet no evidence from randomized studies on the optimal duration of antibiotic therapy.
- Trial name
- PIRATE (NCT03101072)
- Testing
- "Fixed long" antibiotic course of 14 days, "Fixed short" antibiotic course of 7 days, "Individualized duration" of antibiotic therapy
- Where
- 3 sites in Switzerland
- Volunteers
- 504 people
- Sponsor
- University of Geneva, Switzerland