Clinical trials: Remote Ischaemic Preconditioning
Lung Injury, Remote Ischemic Preconditioning
Remote Ischemic Preconditioning on Pulmonary Injury in Cardic Surgery
During cardiac surgery with cardiopulmonary bypass , pulmonary dysfunction remains to be a problem complicating the postoperative course of the patients.Remote ischemic preconditioning(RIPC) with transient upper limb…
- Trial name
- NCT03016182
- Testing
- Remote Ischemic Preconditioning, Control
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xuzhou Medical University
Coronary Artery Disease
Remote Ischemic Preconditioning in ad Hoc Percutaneous Coronary Interventions
Elective percutaneous coronary intervention (PCI) is associated with troponin release in approximately one third of cases. Myocardial necrosis may result from downstream embolization of atheromatous material, coronary side-branch…
- Trial name
- NCT01158716
- Testing
- Remote Ischemic Preconditioning
- Where
- Greece
- Volunteers
- 94 people
- Sponsor
- Cardiovascular Research Society, Greece
Liver Diseases
Ischemic Preconditioning at a Distance in Liver Surgery
During hepatic transection, it exists a high risk of perioperative blood loss. The haemorrhage and its consequences (hypovolemia and blood transfusion) might impact the short and long term morbidity The vascular control by…
- Trial name
- HEPATOPROTECT (NCT04181502)
- Testing
- pneumatic tourniquet, No inflation
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Peripheral Vascular Diseases
Effects of Remote Ischemic Preconditioning on Restenosis Post Lower Limb Revascularization Angioplasty
The investigators will established relation between restenosis and inflammatory response to shearing stress caused by angioplasty suggest that any mechanism that affect inflammatory response can consequently affect the restenosis…
- Trial name
- NCT02406131
- Testing
- Remote Ischemic Preconditioning
- Where
- 2 sites in Ireland
- Volunteers
- 40 people
- Sponsor
- National University of Ireland, Galway, Ireland
Postoperative Complication
Effect of Remote Ischemic Preconditioning on Postoperative Complications in Visceral Surgery
Remote Ischemic Preconditioning (RIPC) is mediated by intermittent brief episodes (5-10 minutes) of short ischemia in a limb (i.e. arm), followed by reperfusion.
- Trial name
- RIPC (NCT02375269)
- Testing
- RIPC with a tourniquet
- Where
- Switzerland
- Volunteers
- 526 people
- Sponsor
- University of Zurich
Brain Injuries, Remote Ischemic Preconditioning
Remote Ischemic Preconditioning on Brain Injury in Carotid Endarterectomy
This is a randomized controlled trial designed to test an intervention (Remote ischemic preconditioning) in patients undergoing carotid endarterectomy (CEA).Remote ischemic preconditioning(RIPC) with transient upper limb…
- Trial name
- NCT03027011
- Testing
- Remote Ischemic Preconditioning, Control
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Peripheral Vascular Disease
RCT to Evaluate the Renal Protective Effects of Remote Ischaemic Preconditioning in Peripheral Angioplasty
This study aims to demonstrate if remote ischaemic preconditioning (RIPC) may confer renal protection in patients undergoing peripheral angioplasty.
- Trial name
- NCT02054871
- Testing
- RIPC
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mid Western Regional Hospital, Ireland
Autoimmune Diseases, Infection
the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia
In a wide range of auto-inflammatory and infectious diseases attenuation of the immune response could be beneficial. Remote ischemic preconditioning (RIPC) has been identified as a means of protecting patients undergoing cardiac…
- Trial name
- RISPENDO (NCT02602977)
- Testing
- Multiple-dose Remote Ischemic Preconditioning, Single-dose Remote Ischemic Preconditioning, LPS infusion
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Remote Organ Ischemic Preconditioning
The Effects Of Remote Organ Ischemic Preconditioning On Systemic Inflammatory And Glycocalyx Integrity Parameters
Ischemia-reperfusion (IR) injury during liver transplantation is one of the major causes of mortality and morbidity associated with transplantation.
- Trial name
- NCT04216407
- Testing
- Remote ischemic preconditioning
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Acibadem University
Ischemia-reperfusion (IR) Injury
Clinical and Genomic Responses to Open Heart Surgery
This study will be the first large scale randomized study of remote ischemic preconditioning (RIPC) ever performed and will define the role of this novel therapy as a clinical tool.
- Trial name
- NCT00650507
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- The Hospital for Sick Children
Acute Kidney Injury
Remote Ischemic Preconditioning to Prevent Contrast Nephropathy
Contrast-medium induced nephropathy (CIN) is a frequent and devastating complication of coronary angiography, occurring in 10-50% of cases.
- Trial name
- RIPC-CIN (NCT02674451)
- Testing
- Remote ischemic preconditioning
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Johns Hopkins University
Acute Lung Injury
Effects of Remote Ischemic Preconditioning and Postconditioning on Lung Injury During Cardiopulmonary Bypass
Remote Ischemic Preconditioning(RIPC) and remote ischemic postconditioning(RIPoC) seems to have a protective effect during ischemic period.
- Trial name
- NCT01144585
- Testing
- remote ischemic preconditioning and postconditioning, Control
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Seoul National University Hospital
Myocardial Injury
Remote Ischemic Preconditioning in Coronary Artery Bypass Grafting With Cold Crystalloid Cardioplegic Arrest
Remote ischemic preconditioning (RIPC) with transient upper limb ischemia/reperfusion reduces myocardial injury in patients undergoing on-pump coronary artery bypass (CABG) surgery with cross-clamp fibrillation or blood…
- Trial name
- NCT01406678
- Testing
- RIPC, Control, isoflurane+sufentanil anesthesia
- Where
- Germany
- Volunteers
- 1,204 people
- Sponsor
- University Hospital, Essen
Nephropathy
Interest of Remote Ischemic Preconditioning for Prevention of Contrast Medium-induced Nephropathy in High Risk Patients
Diagnostic imaging for vascular investigations and endovascular procedures frequently require the use of contrast medium. Besides contrast medium-induced hypersensitivity, an acute kidney injury can appear: the contrast-induced…
- Trial name
- IPC-Angio (NCT02470247)
- Testing
- Remote Ischemic Preconditioning (RIPC)
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Rennes University Hospital
Acute Kidney Injury, Coronary Artery Bypass
Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery
Background: Acute kidney injury (AKI) following coronary artery bypass graft (CABG) surgery is a major complication occurring in 1% to 53% of patients (depending on how it is defined) with the pooled rate of 18.2% and…
- Conditions
- Acute Kidney Injury, Coronary Artery Bypass, Ischemic Preconditioning
- Trial name
- NCT02981680
- Testing
- Remote Ischemic Preconditioning (RIPC)
- Where
- Iran
- Volunteers
- 180 people
- Sponsor
- Shiraz University of Medical Sciences
Atrial Fibrillation
Effect of Remote Ischemic Preconditioning on Electrophysiological and Biomolecular Parameters in Non-valvular Paroxysmal Atrial Fibrillation: RIPPAF Study
The aim of the study is to examine the effect of RIPC on physiological parameters in non-valvular paroxysmal atrial fibrillation.
- Trial name
- RIPPAF (NCT02779660)
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- Germany
- Volunteers
- 146 people
- Sponsor
- Jedrzej Kosiuk
Elderly Patients, Non-cardiac Surgery
Effects of Limb Remote Ischemic Preconditioning for Prevention of Delirium in Elderly Patients After Non-cardiac Surgery
To investigate whether limb remote ischemic preconditioning (LRIP) could safely decrease the incidence of delirium in elderly patients after non-cardiac surgery.
- Trial name
- LRIP-D (NCT03028389)
- Testing
- limb remote ischemic preconditioning(LRIP)
- Volunteers
- 611 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Patients With Elective Aortic Valve Replacement
Remote Ischemic Preconditioning Induces Myocardial RISK Signaling Pathway in Patients Undergoing Valvular Heart Surgery
The aim of this study is to investigate whether RIPC protects the heart against ischemia reperfusion injury on the concentrically hypertrophied myocardium
- Trial name
- NCT01946087
- Testing
- Remote ischemic preconditioning at left upper arm, Control group
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Yonsei University
Cardiac Function and Preconditioning
Effects of Remote Cardiac Ischemic Preconditioning
A heart attack occurs when blood flow is disrupted to the heart and is related to both the blockage and flow restoration (reperfusion injury).
- Trial name
- NCT06390358
- Testing
- Tefillin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jack Rubinstein
Chronic Kidney Disease
Reducing Hemodialysis Induced Recurrent Brain Injury to Improve Patients' Lives
Patients who receive dialysis for kidney failure suffer severe cognitive impairment. Hemodialysis causes circulatory stress and ischemia, which causes severe brain injury.
- Trial name
- NCT03342183
- Testing
- Intervention Arm, Control Arm
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's