Clinical trials: Renal Stone Disease
Renal Calculi
FANS VS DISS in Treatment of Renal Stone < 2cm
To compare between FANS \& DISS in : Operative time Stone free rate Complications Amount of fluid irrigation
- Trial name
- NCT07559214
- Testing
- Flexible ureteroscopy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Stone Ureter, Stone;Renal
Clinical Trial Evaluating the Efficiency of Holmium Laser Settings on Urinary Stones
The primary objective of this study is to compare the time to acceptable stone fragmentation during clinical use of the holmium laser when using energy settings 0.2J vs 0.8J.
- Conditions
- Stone Ureter, Stone;Renal, Surgery
- Trial name
- NCT03526458
- Testing
- Holmium:YAG laser
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Madison
Renal Calculi
External Physical Vibration Lithecbole Versus Traditional Row of Stone After Extracorporeal Shockwave Lithotripsy(ESWL)
The traditional stone row method comprises increasing exercise, drink lots of water, drug row of stone and stone row position. External physical vibration lithecbole(EPVL) is a non-invasive device active row of stone, the…
- Trial name
- NCT02643134
- Testing
- extracorporeal shockwave lithotripsy, External Physical Vibration Lithecbole
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stone
Effect of a DASH-Style Diet on Urinary Risk Factors for Kidney Stone Disease
The true capacity for a healthy diet to improve urinary stone risk factors is not well-defined. The objective of this study is to measure the effect of adopting a healthy dietary pattern on kidney stone disease (KSD) risk.
- Trial name
- NCT06210009
- Testing
- DASH-Style Diet, Western-Style Diet
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Alabama at Birmingham
Kidney Stone, Nephrolithiasis
Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention
The aim of this randomized trial with a 2-by-2 factorial design is to test the efficacy of the SGLT2 inhibitor empagliflozin and personalized dietary counseling based on 24-hr urine collection results and dietary assessments for…
- Conditions
- Kidney Stone, Nephrolithiasis, Dietary Exposure
- Trial name
- EMPASTONE (NCT06653738)
- Testing
- Empagliflozin 10 MG, Personalized dietary counseling, Generic dietary counseling
- Where
- 21 sites in France, Germany and 2 more
- Volunteers
- 400 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Stone, Nephrolithiasis
Comparison of SP TFL and Ho:YAG for RIRS Using 145 µm and 200 µm Fibers
The authors hypothesize that the RIRS using 150-microm Tm-fiber laser is superior than fiber with larger diameters, as 200-microm Tm-fiber laser or 200-microm holmium fiber laser, in such points as follows: decreasing surgery…
- Conditions
- Kidney Stone, Nephrolithiasis, Urolithiasis
- Trial name
- NCT04346485
- Testing
- SP TFL RIRS with 145 mcm fiber, SP TFL RIRS with 200 mcm fiber, Ho:YAG RIRS with 200 mcm fiber
- Where
- Russia
- Volunteers
- 105 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Kidney Calculi, Ureter Calculi
Naftopidil 75mg for Improving Clearance of Urinary Stones
The purpose of this study is to evaluate Efficacy and Safety of oral intake of Naftopidil 75mg once daily for the improving clearance of ureteral or renal stones.
- Trial name
- NCT02011737
- Testing
- naftopidil 75mg
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Samsung Medical Center
Kidney Stone
Adjunct Inversion for Lower Pole Stone
This is a randomized controlled trial comparing extracorporeal shockwave lithotripsy (ESWL) with and without simultaneous adjunct controlled inversion therapy in the treatment of lower pole caliceal stone.
- Trial name
- NCT01852669
- Testing
- Inversion, Shock Wave Lithotripsy, Hydration
- Volunteers
- 140 people
- Sponsor
- Monash University
Postoperative Pain, Nephrolithiasis
A Randomized, Double-Blind, Placebo-Controlled Trial of Anrikefon for Postoperative Analgesia After Percutaneous Nephrolithotomy
This study evaluates whether a single dose of anrikefon, given intravenously shortly before the end of kidney stone removal surgery (PCNL), can reduce opioid-related side effects such as nausea, vomiting, itching, oversedation…
- Trial name
- ARK-PCNL (NCT07825142)
- Testing
- Anrikefon
- Volunteers
- 160 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Stone, Kidney, Urolithiasis
Optimal Passive Dilation Time in Retrograde Intrarenal Surgery
Retrograde intrarenal surgery (RIRC) is used as standard treatment for stones less than 2 cm. In some cases, the ureteral access sheath cannot be placed due to ureteral stricture.
- Trial name
- NCT05340088
- Testing
- Retrograde intrarenal surgery after DJ stent placement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Training and Research Hospital
Catheter Blockage, Oncology
A Novel Ureteric Stent in Kidney Stone Patients and Oncology Patients Compared to a Conventional JJ Stent
Urological stents and catheters often lead to inflammation, causing pain and infection in the urinary tract. Moreover, 80% of stents are associated with pain, negatively impacting on QoL and mental health.
- Conditions
- Catheter Blockage, Oncology, Kidney Stone
- Trial name
- CASSETTE (NCT06815120)
- Testing
- Experimental ureteric stent with specially shaped side-holes that prevent stagnation points (i.e., areas of low flow that cause particles to settle and E&B), Qualitative interview
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Southampton
Kidney Stones, Retrograde Intrarenal Surgery
The Role of Preoperative Ureteral Diameter Measurements in Predicting Difficult Access During Retrograde Intrarenal Surgery: A Retrospective Analysis of 234 Patients
This study investigates the role of preoperative ureteral diameter measurements in predicting difficult access during retrograde intrarenal surgery (RIRS) in patients with kidney stones.
- Conditions
- Kidney Stones, Retrograde Intrarenal Surgery, Difficult Ureteral Access Prediction
- Trial name
- NCT06746779
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 234 people
- Sponsor
- Hisar Intercontinental Hospital
Kidney Calculi
The Effect of Education Given to Patients on Pre- and Post-operative Anxiety and Preparation for Discharge
The data of the randomized controlled experimental research were collected at Atatürk University Health Application and Research Hospital Urology Clinics between November 2021 and May 2022.
- Trial name
- NCT05511545
- Testing
- Patient Education Booklet
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Kidney Stones, Complex Renal Calculi
Modified Mini-PCNL Versus Standard PCNL for Complex Kidney Stones
Kidney stones that are large or complex are often treated with percutaneous nephrolithotomy, also called PCNL. Standard PCNL uses a larger access tract and is effective for removing complex kidney stones, but it may be associated…
- Trial name
- MIMIC-PCNL (NCT07697677)
- Testing
- 20 Fr Modified Mini Percutaneous Nephrolithotomy, 24 Fr Standard Percutaneous Nephrolithotomy
- Where
- China
- Volunteers
- 1,380 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Nephrolithiasis
Thulium vs. Hol:YAG Laser
This is a randomized prospective study to compare stone free rates and operative efficiency of two laser systems used during retrograde intrarenal surgery for kidney stone disease: 1.
- Trial name
- NCT05808257
- Testing
- Thulium Fibre Laser, Holmium:Yttrium-Aluminum-Garnet
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Kidney Stone, Urolithiasis, Calcium Oxalate
Heterozygous Individuals for AGXT and Kidney Stones
This study seeks to examine the effects of a heterozygous mutation of the AGXT gene in a stone forming population on endogenous oxalate production.
- Trial name
- NCT04430426
- Testing
- Controlled Diet
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Alabama at Birmingham
Kidney Stone, Ureteral Stone
High Powered Stone Dusting vs. Fragmentation and Basketing at Time of Ureteroscopy
The purpose of this study is to determine the differences in stone free results, patient side effects, and patient satisfaction between dusting vs.
- Trial name
- NCT05006937
- Testing
- Dusting, Basket extraction
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Northwestern University
Kidney Stones, Nephrolithiasis
Empiric Versus Selective Prevention Strategies for Kidney Stone Disease
The aims of this study are to 1) Conduct a randomized clinical trial of selective versus empiric diet plus pharmacologic therapy in high-risk stone formers and 2) Determine adverse effects from, and adherence to selective and…
- Trial name
- NCT05365477
- Testing
- Empiric Therapy: Diet, Empiric Therapy: Drug, Selective Therapy: Diet
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Vanderbilt University Medical Center
Kidney Stone
Research on Early Warning and Diagnosis & Treatment Pathway for Micro Kidney Stones
Exploring abnormal metabolism in kidney stone patients and developing drugs for kidney stone treatment and their mechanisms of action.
- Trial name
- NCT07350369
- Testing
- Detect the levels of metabolites in blood and urine
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Kidney Calculi
Comparing Super Pulse Fiber Thulium Laser and Holmium Laser for Ureteral Stone Fragmentation During Ureteroscopy
The goal of this prospective, multicenter, randomized controlled trial is to objectively evaluate the clinical efficacy and safety differences between superpulse thulium fiber laser (sTFL) and holmium:YAG laser (Ho:YAG) in…
- Trial name
- NCT06667557
- Testing
- Superpulse Thulium Fiber Laser (sTFL) Treatment, Holmium:YAG Laser (Ho:YAG) Treatment
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine