Clinical trials: Replacement
Arthritis
Followup of Glenoid Fix Utilizing Auto Bone Graft in Shoulder Replacement
This is a case study to evaluate the adequacy of fixation and functional outcome of the glenoid anchor peg following autologous bone grafting around the prosthesis at the time of implant.
- Trial name
- NCT00670852
- Testing
- X-rays and CT scan
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Survival, Prosthesis
Clinical Assessment of All Ceramic Single-retainer Using Upper Canine as Abutment With Minimum Preparation on the Lingual Surface, to Replace the Upper Lateral Incisor and Will be Compared With the All Ceramic Single-retainer Using Upper Central Incisor.
The Intervention Will be All Ceramic Single-retainer Resin Bonded Fixed Partial Denture Using the Upper Canine as Abutment With Minimum Preparation on the Lingual Surface Within the Enamel Providing Maximum Area for the Retainer…
- Trial name
- NCT05812066
- Testing
- all ceramic single-retainer resin bonded fixed partial denture
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hip Osteoarthritis, Indication for Total Hip Replacement
Evaluation of Locomotor Activity Before and After Total Hip Replacement in Patients With Hip Osteoarthritis.
The investigators believe that the application of non-linear methods of analysis using the ganglion and neural network technique will make it possible to analyse all of the complex data obtained in patients with hip…
- Trial name
- NCT02042586
- Testing
- Analysis of movement before total hip replacement, Analysis of movement after total hip replacement
- Where
- France
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Menopause, Perimenopausal Disorder
A New Hormone Replacement Paradigm: Physiologic Restoration Study
This is a three-year, prospective, observational study looking at the benefits of rhythmically dosed, bio-identical hormones compounded in a carrier cream in 100 symptomatic peri and postmenopausal women.
- Conditions
- Menopause, Perimenopausal Disorder, Menopause Related Conditions
- Trial name
- NCT04190927
- Testing
- Compounded topical estradiol and compounded topical progesterone in a carrier cream
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Women's Hormone Network
Gaucher Disease, Type III
Eliglustat on Gaucher Disease Type IIIB
Evaluation of the safety in the combination usage of Cerdelga and Cerezyme in type III Gaucher disease patients and the efficacy on soft tissue diseases.
- Trial name
- NCT03519646
- Testing
- Eliglustat
- Where
- Taiwan
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Frozen Embryo Transfer
Benefit of Amlodipine in HRT Cycle for Frozen Embryo Transfer in the Correction of Uterine Pulsatility Index
Embryo implantation depends on two main factors: embryo grading quality and endometrial receptivity.Numerous tools have been suggested to evaluate these two factors.
- Trial name
- AMLODIP (NCT04954196)
- Testing
- Amlodipine 5mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Total Knee Replacement
Long Term Foundation Knee Study
The purpose of this study is to obtain long-term (10+ yrs) clinical and patient outcomes data on patients who received the cruciate-retaining Foundation Knee system during or prior to the year 2000.
- Trial name
- NCT01274546
- Testing
- cruciate-retaining Foundation Knee system
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Encore Medical, L.P.
Blood Loss, Surgical, Blood Transfusion
Bleeding in Knee Arthroplasty After Preconditioning With Sevoflurane
Knee arthroplasty is performed with restriction of blood flow by use of the pressure tourniquet. Ischemia of skeletal musculature is accompanied by the formation of reactive oxygen species and release of vasoactive factors.
- Trial name
- NCT03379103
- Testing
- Sevoflurane, Propofol
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Regional Citrate Anticoagulation, Ionized Calcium
No Monitoring of Post-filter Ionized Calcium in Regional Citrate Anticoagulation
Do no monitor of post-circuit ionized calcium affact the filter life time of continueous renal replacement therapy with regional citrate anticoagulation circuit? A randomized control trial
- Conditions
- Regional Citrate Anticoagulation, Ionized Calcium, Continuous Renal Replacement Therapy
- Trial name
- NCT04792424
- Testing
- Regional citrate anticoagulation, Vasopressor, Antibiotic
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Drug Addiction, Smoking Cessation
Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3
Treatment studies have demonstrated that current smoking cessation techniques are less effective for women. The purpose of this study is to determine the role that gender plays in the effectiveness of nicotine replacement…
- Trial name
- NCT00390559
- Testing
- nicotine transdermal system, Nicotine containing cigarette
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Osteoarthritis, Total Knee Replacement
Adductor Canal Block
The investigators aim to investigate whether the addition of a surgeon-administered adductor canal blockade to a multimodal periarticular injection cocktail provides additional pain relief for patients undergoing total knee…
- Trial name
- NCT04513145
- Testing
- Ropivacaine injection, Saline Injection, Total Knee Arthroplasty
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- OrthoCarolina Research Institute, Inc.
Weight Gain
Food Replacement on Weight Control in Overweight Volunteers
Volunteers will be divided into two groups which are protein and oil supplement group and normal dietary group. For protein and oil supplement group, they will take 1 sachet of product replaced dinner every day for 8 weeks.
- Trial name
- NCT06488339
- Testing
- Protein and oil supplement
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Osteoarthritis of the Knee
Total Knee Replacement Study Using Standard Cutting Guide vs Otismed MRI Generated Cutting Guide
Patients are referred to the VA orthopedic surgical clinic because of osteoarthritis and are requesting consideration for a total knee replacement. Those who qualify for the knee replacement are informed about the study.
- Trial name
- NCT00837772
- Testing
- Standard cutting guide for TKA, Otismed MRI generated cutting guide for TKA
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Phoenix VA Health Care System
Idiopathic Hypogonadotropic Hypogonadism
Effects of Gonadotropin Replacement Therapy on Metabolic Parameters in Patients With Hypogonadism
Effects of gonadotrophin replacement therapy Lipid Profile and Oxidative Stress Parameters of Patients with Idiopathic Hypogonadotropic Hypogonadism
- Trial name
- NCT02728440
- Testing
- human chorionic gonadotropin, human menopausal gonadotropin
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Knee Replacement, Knee Replacement Revision
Prevalence and Incidence of Multiple Revisions Following Knee Arthroplasty in Denmark 1998-2021: A Nationwide Population-based Study
The purpose of this study is to investigate the incidence and prevalence rates of multiply revised knee arthroplasty patients in Denmark from 1998-2021.
- Trial name
- EMKAR ONE (NCT06064318)
- Testing
- Revision
- Where
- Denmark
- Volunteers
- 161,384 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Arthrofibrosis
STAK Tool for Treatment of Arthrofibrosis Post Total Knee Replacement
A common complication following total knee replacement (TKR) is arthrofibrosis, a severe stiffening of the knee caused by scar tissue.
- Trial name
- STAK (NCT04019847)
- Testing
- STAK Tool, Standard treatment
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Osteoarthritis
The Use of Compression Bandages in Total Knee Replacement Surgery
The use of compression bandages in elective orthopaedic knee surgery is well regarded, however, there is a lack of robust, well-designed evidence to support this.
- Trial name
- NCT02253680
- Testing
- Actico, short-stretch, inelastic dressing
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Northumbria Healthcare NHS Foundation Trust
Mitral Regurgitation, Mitral Valve Disease
Munich Transcatheter Mitral Valve Safety and Effectiveness
The Munich Trascatheter Mitral Valve System is intended for beating heart, mitral valve replacement in patients with a diseased, damaged, or malfunctioning mitral valve.
- Trial name
- MUSE (NCT05871983)
- Testing
- MUNICH TRANSCATHETER MITRAL VALVE REPLACEMENT SYSTEM
- Where
- 10 sites in Argentina, Brazil and 1 more
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- P+F Products + Features GmbH
Missing Teeth
No-preparation Resin Bonded Bridges for the Replacement of Single Missing Teeth
Tooth replacement is a significant issue in the World. Such replacement is considered important by patients to improve aesthetics, function and quality of life. Tooth replacement is therefore a significant issue.
- Trial name
- NCT03029637
- Testing
- RBBs with no or minimal preparation of their abutment teeth, RBBs with routine tooth preparation of their abutment teeth
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Total Knee Replacement
Comparative Effect of Instrument Assisted Soft Tissue Mobilization and Cross Fiber Massage in Patients With Total Knee Replacement.
Comparative effect of Instrument Assisted Soft Tissue Mobilization and Cross Fiber Massage in patients with Total Knee Replacement
- Trial name
- NCT07361770
- Testing
- Instrument-assisted soft tissue mobilization, Cross Fibre Massage
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rashid Latif Medical College