Clinical trials: Resorption
Dental Crowding, Alveolar Bone Loss
Bone Level Changes Using Clear Aligners Compared to Fixed Appliances in Non-Extraction Treatment of Adults
This study compares two common ways of straightening teeth in adults who have mild-to-moderate crowding of the lower front teeth and do not need any teeth removed: clear aligners and traditional fixed braces.
- Conditions
- Dental Crowding, Alveolar Bone Loss, Malocclusion
- Trial name
- NCT07716007
- Testing
- Fixed orthodontic appliance, Clear aligners
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Periodontal Bone Loss
Erythropoietin Gel as an Adjunct to Xenograft in the Surgical Management of Intrabony Periodontal Defects
The aim of the study is to evaluate the use of erythropoietin gel as an adjunct to xenograft in the surgical management of intrabony periodontal defects.
- Trial name
- NCT05360511
- Testing
- particulate xenograft + erythropoietin gel., particulate xenograft
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Alveolar Bone Loss, Edentulous Jaw
Alloplastic Graft vs Xenograft for Horizontal Alveolar Ridge Augmentation
This prospective split-mouth randomized controlled trial compared horizontal alveolar ridge augmentation using alloplastic bone graft versus xenograft, both performed simultaneously with implant placement using the decompression…
- Trial name
- NCT07608744
- Testing
- Alloplastic bone graft, Xenograft
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ege University
Alveolar Bone Loss, Tooth Extraction
Evaluation of Stem Cell Exosomes Versus Platelet-Rich Fibrin in Tooth Extraction Socket Healing
This study evaluates two different treatments used to help the jawbone heal after a tooth is removed. When a tooth is extracted, the surrounding bone often shrinks, which can make it difficult to place dental implants later.
- Conditions
- Alveolar Bone Loss, Tooth Extraction, Bone Regeneration
- Trial name
- MSC-EXO vs PRF (NCT07508033)
- Testing
- MSC-Derived Exosomes, Platelet-rich fibrin (PRF)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al Salam University
Root Resorption
An Evaluation of Root Length Measurements Using Intraoral Scan and Panoramic Radiographs
This study will attempt to validate a method of estimating root length on panoramic radiograph by crown measurement on intraoral digital scans.
- Trial name
- NCT02822040
- Testing
- Intraoral Scan
- Volunteers
- 21 people
- Sponsor
- Loma Linda University
Osteoporosis, Postmenopausal, Osteoporosis
Early Effects of Abaloparatide on Tissue-Based Indices of Bone Formation and Resorption
The objective of this study is to measure the early effects of abaloparatide on tissue-based bone formation using samples obtained by transiliac crest bone biopsy after quadruple fluorochrome labeling.
- Conditions
- Osteoporosis, Postmenopausal, Osteoporosis, Osteoporosis Vertebral, Osteoporosis Risk
- Trial name
- NCT03710889
- Testing
- Abaloparatide
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Radius Health, Inc.
Alveolar Bone Loss, Edentulous Maxilla, Atrophic
Guided Bone Regeneration Combined With PRGF for Atrophic Edentulous Maxilla
This prospective interventional clinical study evaluated guided bone regeneration combined with plasma rich in growth factors for vertical and horizontal augmentation of the atrophic edentulous maxilla.
- Conditions
- Alveolar Bone Loss, Edentulous Maxilla, Atrophic, Alveolar Ridge Deficiency, Jaw Atrophy
- Trial name
- GBR-PRGF-Maxil (NCT07654218)
- Testing
- Guided Bone Regeneration Combined With Plasma Rich in Growth Factors
- Where
- Portugal
- Volunteers
- 11 people
- Sponsor
- Universidade do Porto
Alveolar Bone Resorption, Sequela
Bone Material Comparison in Maxillary Sinus Augmentation
Hard and soft tissue deficiencies of an alveolar ridge arise as sequelae of tooth extraction when socket preservation is not applied.
- Conditions
- Alveolar Bone Resorption, Sequela, Tooth Extrusion
- Trial name
- NCT04433117
- Testing
- Shefabone, Bio-Oss
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohanad Al-Sabbagh
Deep Bite Malocclusion, Intrusion of Tooth
Maxillary Incisor Intrusion Using Utility Arch Assisted With Micro-osteoperforations
Study will be directed to evaluate the dentoalveolar changes following maxillary incisor intrusion using utility arch assisted with micro-osteoperforations in deep bite cases.
- Conditions
- Deep Bite Malocclusion, Intrusion of Tooth, Orthodontic Tooth Movement, Root Resorption
- Trial name
- MOPs (NCT07566676)
- Testing
- Micro-osteoperforations, Utility arch
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Al-Azhar University
Jaw, Edentulous, Partially, Bone Resorption
Clinical and Radiographic Evaluation of UV-Treated Dental Implants With or Without Melatonin in the Upper Posterior Jaw
The purpose of this study is to evaluate and compare the clinical and radiographic outcomes of using photofunctionalized (UV-treated) dental implants with or without the application of melatonin hormone in the posterior maxilla…
- Conditions
- Jaw, Edentulous, Partially, Bone Resorption, Dental Implant Failure
- Trial name
- UV-MEL-IMPLANT (NCT07853976)
- Testing
- UV-Photofunctionalized Dental Implant, Conventional Dental Implant
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bone Loss, Alveolar, Resorption, Bone
The Effect of Growth Factor on Implant Osseointegration
In this study, concentrated growth factor obtained by centrifuging the patient's own blood and advanced platelet-rich fibrin liquids were applied to the implant cavity and surface.
- Conditions
- Bone Loss, Alveolar, Resorption, Bone, Osseointegration Failure of Dental Implant
- Trial name
- NCT04879446
- Testing
- Concentrated growth factor(CGF), Advanced platelet rich fibrin (A-PRF), Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Uğur Can ÜNLÜGENÇ
Dental Implant Failure, Periodontal Bone Loss
A Retrospective Analysis of Failures of Oral Implants
The purpose of this retrospective study is to investigate and identify factors associated with the failure of dental implants within the population rehabilitated with dental implants at the Folktandvården Specialistklinik in…
- Trial name
- NCT02369562
- Testing
- Evaluation of the failure rate of dental implants
- Where
- Sweden
- Volunteers
- 2,670 people, healthy volunteers welcome
- Sponsor
- Malmö University
Alveolar Bone Atrophy
Efficacy in Alveolar Bone Regeneration With Autologous MSCs and Biomaterial in Comparison to Autologous Bone Grafting
A randomized controlled clinical multi center trial to assess the efficacy of a combination of autologous mesenchymal stem cells and biomaterial in jaw bone regeneration prior to dental implant placement in comparison to standard…
- Trial name
- Maxibone (NCT04297813)
- Testing
- Advanced medicinal Therapy (MSC combined with biomaterial), Autologous bone graft
- Where
- 6 sites in Denmark, France and 2 more
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Overweight, Metabolic Syndrome X
Health of Young European Families and Fish Consumption
This is a controlled, randomized, intervention trial (CRIT) with 20-40 year old overweight individuals (n = 320) across Europe in order to distinguish between biologically active components of seafood, i.e., seafood proteins and…
- Conditions
- Overweight, Metabolic Syndrome X, Bone Resorption
- Trial name
- NCT00315770
- Testing
- weight loss diets for young adults
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Edentulous Alveolar Ridge With Labial Resorption
Extraction Socket Augmentation. A Clinical Study
Extraction socket preservation is defined as alveolar ridge preservation within the bone envelope remaining after tooth extraction, meanwhile ridge augmentation is defined as increasing the volume of alveolar ridge beyond the…
- Trial name
- GTO (NCT06378112)
- Testing
- GTO®
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
Bone Loss, Alveolar
Effect of Collagen Versus PRF on BMA Osteogenic Potential
Utilization of collagen vs PRF membrane over the graft following sinus lift procedure and before suturing
- Trial name
- NCT05985317
- Testing
- Collagen membrane over BMAC/bovine graft in sinus lift, PRF membrane over BMAC/bovine graft in sinus lift
- Where
- Egypt
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cairo University
Amount of Labial Bone Thickness, Amount of Root Resorption
Assessment of Changes in Labial Bone Thickness and Root Surface After Enmasse Retraction With and Without Hard Laser Assistance
Assessment of Changes in Labial Bone Thickness and Root Surface After Enmasse Retraction With and Without Hard Laser Assistance:Comparative Randomized Cllinical Trial
- Trial name
- NCT07320352
- Testing
- Hard laser therapy biolase device, Enmass retraction without hard laser
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Faculty of Dental Medicine for Girls
Implant Complication, Bone Resorption
Standard Implants With Bone Regeneration vs Short Implants
A study designed as a randomized controlled trial of parallel group design will be conducted at the Dental clinic of the University of Valencia to compare, considering different parameters, the rehabilitation with dental implants…
- Trial name
- NCT03524885
- Testing
- Short implant placement, Bone regeneration with longer implants
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Osteolysis
Denosumab for Treating Periprosthetic Osteolysis.
The main objective is to study the efficacy of denosumab in reducing wear-induced osteolysis around uncemented acetabular implants used in total hip arthroplasty.
- Trial name
- NCT02299817
- Testing
- Denosumab
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Olof Skoldenberg
Bone Substitutes, Alveolar Bone Grafting
Bone Augmentation Techniques in the Mandible Posterior Region
This study will compare three methods to rebuild lost bone in the back part of the lower jaw (posterior mandible) before dental implant placement.
- Trial name
- NCT06661447
- Testing
- Cortical Shell Bone Grafting
- Where
- Ecuador
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo