Clinical trials: Resorption
Bone Resorption, Symptoms
Microsurgery Using a Bioceramic Root End Filling Material
Endodontic failures are not uncommonly encountered despite improvements in routine root canal therapy. Endodontic microsurgery is one way to manage such failure.
- Trial name
- microsurgery (NCT03733938)
- Testing
- endodontic microsurgery
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- Jordan University of Science and Technology
Cancer Prostate
Study to Assess Efficacy and Safety of Zoledronic Acid and the Value of Markers of Bone Resorption in the Prediction of Bone Metastases and Cancer Treatment-induced Bone Loss (CTIBL) in Patients With Prostate Cancer on Hormone Therapy
The objective of the study is to investigate whether blood markers can be used to predict the development of bone metastases and to assess the efficacy and safety of zoledronic acid in cancer treatment induced bone loss.
- Trial name
- NCT00172055
- Testing
- Zoledronic acid
- Where
- 19 sites in Belgium
- Volunteers
- 218 people
- Sponsor
- Novartis Pharmaceuticals
Alveolar Bone Loss
A Clinical Investigation to Evaluate the Healing of Tooth Extraction Sites Filled With BioRestore™
The aim of this study was to evaluate by histology and MSCT scans during a 7-month period, the efficacy of a bioactive glass (Inion BioRestore™) placed in human extraction sockets in the maintenance of alveolar ridge.
- Trial name
- NCT01105026
- Testing
- Alveolar Bone Defect Regeneration Following Tooth Extraction
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Chronic Periodontitis, Periodontal Bone Loss
Use of the xCELLigence System for Quantification of Bacterial Biofilm's Real Time Formation and Antibiotics Selection.
The aim of the study is to develop an in vitro model of growth of oral biofilms, and validate xCELLigence system for the selection of an effective antibiotic treatment for each patient.
- Conditions
- Chronic Periodontitis, Periodontal Bone Loss, Resistance Bacterial
- Trial name
- NCT03863249
- Testing
- SCALE AND ROOT PLANING, ADJUNTIVE ANTIBIOTICS, MICROBIAL SAMPLING
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- University of Valencia
Alveolar Bone Loss, Tooth Extraction
Reduced Time Interval for Implant Placement After Extraction Socket Preservation Using the Vega Plus Implants
This randomized controlled clinical trial aims to evaluate whether reducing the healing interval for implant placement after extraction socket preservation improves clinical and radiographic outcomes compared with the…
- Trial name
- RIP-VEGA (NCT07484685)
- Testing
- Reduced time interval treatment protocol, Standard time interval treatment protocol
- Where
- Ecuador
- Volunteers
- 40 people
- Sponsor
- Universidad Catolica Santiago de Guayaquil
Dental Implant Failed, Alveolar Bone Loss
Comparison of Narrow and Regular Implants
The study was designed as a retrospective, parallel, two years longitudinal pilot trial. Twenty-eight patients (mean age: 48.34 ± 6.06) aged between 35 and 60 years and 66 TiUnite surfaces (Nobel Biocare Parallel Conical…
- Conditions
- Dental Implant Failed, Alveolar Bone Loss, Complication,Postoperative
- Trial name
- NCT04572490
- Testing
- periapical radiograph
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- T.C. Dumlupınar Üniversitesi
Gorham Disease, Lymphatic Diseases
Imaging of Lymphatic Anomalies
Lymphatic Anomalies (LA) is characterized by proliferation of lymphatic tissue causing deterioration of pulmonary function. Understanding changes in lymphatic anatomy in these patients is hindered by the difficulty of imaging the…
- Conditions
- Gorham Disease, Lymphatic Diseases, Lymphangiomatosis
- Trial name
- NCT02744027
- Testing
- Dynamic Contrast Enhanced Magnetic Resonance Lymphangiography (DCMRL), Heavy Weighted T2 Imaging (T2W), Lymph Node Access
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Perimenopausal Bone Loss, Postmenopausal Osteopenia
Prevention of Osteoporosis: Effects of Mini-trampoline Training on the Bone Remodeling
The aim of the project is to study the effects on bone remodeling induced by training carried out with the trampoline in order to evaluate the reduction of the resorption itself and therefore the onset of osteoporosis in women.
- Trial name
- TRAMBONE (NCT04942691)
- Testing
- physical activity
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Periodontal Attachment Loss, Periodontal Bone Loss
Platelet-Rich Fibrin and Anorganic Bovine Bone vs Collagen Membrane and Anorganic Bovine Bone in Intrabony Defects
The primary outcome of periodontal reconstructive therapy is to regenerate all tissues of the periodontium including a functional periodontal ligament, alveolar bone and cementum.
- Conditions
- Periodontal Attachment Loss, Periodontal Bone Loss, Periodontal Diseases
- Trial name
- NCT03715374
- Testing
- Periodontal Surgery with PRF+ABB, Periodontal Surgery with Collagen Membrane +ABB
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Horizontal Alveolar Bone Defect, Alveolar Bone Loss
Evaluation of Mineralized Plasmatic Matrix With and Without Collagen Membrane in Peri-implant Bone Regeneration
This study focuses on comparing the effect of MPM with or without collagen membrane on delayed implant placement in anterior maxillary aesthetic zone.
- Trial name
- NCT04816110
- Testing
- mineralized plasmatic matrix with collagen membrane, mineralized plasmatic matrix (MPM) without collagen membrane
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Alveolar Bone Loss
Comparison of Customized Allogenic Versus Autogenous Bone Block Graft for Alveolar Ridge Augmentation
The aim of this study is to determine whether jawbone augmentations using allogeneic and autogenous bone blocks lead to comparable three-dimensional clinical and radiological outcomes.
- Trial name
- IndiALLO (NCT07419269)
- Testing
- Alveolar socket preservation with graft and flap surgery, allogenic bone block augmentation
- Where
- Austria
- Volunteers
- 26 people
- Sponsor
- Medical University of Graz
Periodontal Bone Loss
Effect of Orthodontic Treatment on Periodontally Compromised Dentition- Randomised Control Trial
The main aim of this prospective, randomized controlled clinical study is to: To evaluate and compare the effect of a combined orthodontic -periodontal treatment protocol versus periodontal treatment alone on osseous and non…
- Trial name
- NCT03914339
- Testing
- Periodontal and orthodontic treatment, periodontal treatment
- Where
- 2 sites in India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Volumetric Root Resorption
Evaluation of Apical Root Resorption in Dental Deep Bite Correction by Twin Slot Orthodontic Bracket
Evaluate the possible apical root resorption during deep bite correction by double slot bracket with low level slot versus high level slot using CBCT.
- Trial name
- NCT06704165
- Testing
- Orthodontic treatment using double slot bracket wire in high level slot, Orthodontic treatment using double slot bracket with wire in low level slot
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Faculty of Dental Medicine for Girls
Tooth Loss, Bone Loss, Alveolar
Immediate Implant Outcomes With and Without Bone Augmentation
To evaluate immediate implant placement feasibility and esthetic outcomes in severely damaged sockets that received simultaneously bone reconstruction (cortical bone shield) and implant placement versus intact sockets that needed…
- Conditions
- Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
- Trial name
- NCT05157009
- Testing
- implant placement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Residual Bone Height, Marginal Bone Loss
Influence of Residual Bone Height on Marginal Bone Loss Around Implants Following Lateral Sinus Floor Augmentation With Deproteinized Bovine Bone Mineral
Data collection will be done on all patients who underwent a lateral maxillary sinus floor augmentation in the Faculty of Dental Medicine, both in the Periodontology Department and in the Oral Surgery Department.
- Conditions
- Residual Bone Height, Marginal Bone Loss, Implant Type, Smoking
- Trial name
- NCT07550491
- Testing
- sinus lift using DBBM
- Where
- Lebanon
- Volunteers
- 142 people
- Sponsor
- Saint-Joseph University
Guided Bone Regeneration
RES-SAFE (Resorption, Safety, and Efficacy of Absorbable Collagen Membrane)
The clinical study aims to assess the long-term safety and efficacy of the interventional medical device. The clinical study will enrol up to 50 patients aged 18 years and older, who meet specific inclusion and exclusion criteria…
- Trial name
- NCT06570265
- Testing
- GBR membrane
- Volunteers
- 50 people
- Sponsor
- Hyundai Bioland Co., Ltd.
Crowding of Anterior Mandibular Teeth
Evaluation of the Root Resorption and Dehiscence Formation Between Two Methods of Leveling and Alignment of Lower Teeth
The duration of orthodontic treatment is one of the exacerbation causes of orthodontic pain. Several methods have been suggested to reduce the duration of orthodontic treatment classified to surgical and non-surgical methods.
- Trial name
- NCT04601662
- Testing
- Corticision, Traditional Non-accelerated Treatment
- Where
- Syria
- Volunteers
- 52 people
- Sponsor
- Damascus University
Alveolar Bone Loss, Edentulism Nos
The Application of a Biphasic Calcium Sulfate Graft Material in Sinus Floor Elevation
Pneumatization of the maxillary sinus may lead to insufficient bone volume for dental implant placement in the edentulous posterior maxilla.
- Trial name
- NCT06533397
- Testing
- Sinus floor elevation (SFE), preoperative cone beam computed tomography (CBCT), postoperative CBCT
- Where
- Hungary
- Volunteers
- 40 people
- Sponsor
- Semmelweis University
Clift Lip, Cleft Palate
Description of Pain in Pediatric Patients With Cleft Lip and Palate Undergoing Alveolar Grafting Using Two Surgical Strategies: Stem Cells and Autogenous Iliac Crest Bone (Pain Evaluation in Children Undergoing Alveolar Grafting: Stem Cells vs. Iliac Crest Bone)
Study Objective The objective of this study was to evaluate and compare postoperative pain and hospital costs in pediatric patients with cleft lip and palate undergoing alveolar bone grafting surgery.
- Conditions
- Clift Lip, Cleft Palate, Alveolar Bone Loss, Postoperative Pain
- Trial name
- NCT07734974
- Testing
- Autogenous Iliac Crest Bone Grafting, Bioengineered Alveolar Grafting (SHED + Scaffold)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Sirio-Libanes
Crestal Bone Loss
Socket Shield Technique Versus Conventional Immediate Implant Placement in Thin Buccofacial Bone
Buccal bone is prone to resorb after tooth extraction specially with immediate tooth implantation which could compromise the esthetics of the patient.
- Trial name
- NCT03264053
- Testing
- Socket shield, Conventional immediate implantation
- Where
- Egypt
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Cairo University