Clinical trials: Respiratory Insufficiency Requiring Mechanical Ventilation
Respiratory Failure, Respiratory Insufficiency
Evaluating Safety and Efficacy of Umbulizer in Patients Requiring Intermittent Positive Pressure Ventilation
Randomized, control crossover study comparing Umbulizer's efficacy to traditional mechanical ventilators
- Conditions
- Respiratory Failure, Respiratory Insufficiency, Respiratory Arrest
- Trial name
- NCT04030208
- Testing
- Umbulizer, Traditional Mechanical Ventilator
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Umbulizer LLC
Acute Respiratory Failure, Shock
Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines
The purpose of this study is to assess the hypothesis that, as compared to early intravenous feeding, early nutrition via the enteral route is associated with reduced Day 28-mortality in critically ill patients treated with…
- Trial name
- NUTRIREA2 (NCT01802099)
- Testing
- Enteral nutrition, Parenteral nutrition
- Where
- 41 sites in France
- Volunteers
- 2,410 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Acute Respiratory Failure
The Tele-Rehab MV Cluster Stepped-Wedge Randomized Clinical Trial
To evaluate, through a randomized clinical trial in groups/clusters (stepped wedge), the impact of specific bundles for disability prevention and early rehabilitation, focused on 3 domains (ICU, ward and post-discharge), on…
- Trial name
- Tele-Rehab MV (NCT06343545)
- Testing
- Standard of Care, Disability Prevention and Rehabilitation
- Where
- 20 sites in Brazil
- Volunteers
- 1,916 people
- Sponsor
- Hospital Israelita Albert Einstein
Respiratory Failure
Cycling of Sedative Infusions in Critically Ill Pediatric Patients
The purpose of this study is to determine if the reduction of the total amount of sedative critically pediatric ill patients receive in the PICU will achieve a significant decrease in mechanical ventilation days and a decrease in…
- Trial name
- NCT01333059
- Testing
- Midazolam, Normal saline, Fentanyl
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Javier Gelvez, MD
Respiratory Failure
Effects of PBMT-sMF in Mechanically Ventilated Patients
The goal of this clinical trial is to evaluate the effectiveness of photobiomodulation therapy combined with static magnetic field (PBMT-sMF) in adult patients who require mechanical ventilation.
- Trial name
- NCT06454006
- Testing
- Active PBMT-sMF
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- University of Nove de Julho
Respiratory Insufficiency Requiring Mechanical Ventilation
Telemonitoring in Home Mechanical Ventilation
Multicentric, observational and longitudinal prospective evaluation of build-in-software data telemonitoring of home ventilators in patients using Home Mechanical Ventilation in Belgium.
- Trial name
- NCT06143384
- Testing
- Telemonitoring AirView (ResMed company)
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Early Mobility, Critically Ill
Early Mobilization in Ventilated SEpsis & Acute Respiratory Failure Study
Early mobilization in Ventilated sEpsis \& acute Respiratory failure Study: EVER Study
- Trial name
- EVER (NCT04582760)
- Testing
- early mobilization
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Acute Respiratory Distress Syndrome, Acute Hypoxemic Respiratory Failure
The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU
While most studies in the medical literature that indicate "music" as an intervention may recognize its impact and capacity to decrease pain perception, anxiety, and/or its role in the regulation of cardiac and respiratory…
- Conditions
- Acute Respiratory Distress Syndrome, Acute Hypoxemic Respiratory Failure, Acute Hypercapnic Respiratory Failure
- Trial name
- NCT03642002
- Testing
- Toning, Ocean drum & SOK melody, SOK
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Respiratory Failure With Acute Decompensation Requiring Mechanical Ventilation for More Than 48 Hours
Early Chair Sitting Exercise in Mechanically Ventilated Critically Ill Patients
The occurrence of an acute respiratory failure necessitates mostly admission to ICU and mechanical ventilation (MV). Rapid and safe discontinuation of MV should be the objective for the majority of patients.
- Trial name
- RehabVent (NCT02021227)
- Testing
- Early chair sitting exercise
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Montpellier
Diaphragm Electrical Activity, Neurally Adjusted Ventilatory Assist
Does Diaphragm Electrical Activity Monitoring Predict Extubation Success in Children?
This study aimed to record diaphragm electrical activity (Edi) during the preextubation (weaning) and postextubation periods and to analyze whether Edi monitoring could predict extubation success.
- Conditions
- Diaphragm Electrical Activity, Neurally Adjusted Ventilatory Assist, Pediatrics
- Trial name
- NCT06163183
- Testing
- Edi catheter
- Volunteers
- 25 people
- Sponsor
- Mersin University
Respiratory Insufficiency Requiring Mechanical Ventilation, Fluid Overload
The Efficient PICU Fluid Care Evaluation
The goal of this clinical trial is to evaluate and prevent fluid overload in critically ill, mechanically ventilated children. The main questions it aims to answer are: 1.
- Conditions
- Respiratory Insufficiency Requiring Mechanical Ventilation, Fluid Overload, Fluid Balance
- Trial name
- LESSER-2 (NCT06644508)
- Testing
- Strict adherence to European guidelines
- Where
- 3 sites in Netherlands
- Volunteers
- 90 people
- Sponsor
- Radboud University Medical Center
Respiratory Failure, Acute Lung Injury (ALI)
Airway Pressure Release Ventilation (APRV) Versus AC/VC Conventional Ventilation
APRV mode of ventilation will result in an improved partial pressure of arterial oxygenation/ fraction of inspired oxygen (P/F ratio) on day 3 of mechanical ventilation.
- Conditions
- Respiratory Failure, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS)
- Trial name
- NCT01339533
- Testing
- Mechanical Ventilation
- Where
- 2 sites in United States
- Volunteers
- 246 people
- Sponsor
- Intermountain Health Care, Inc.
Covid19, Respiratory Failure
Nebulised Heparin in Patients With Severe COVID-19
The Can nebulised HepArin Reduce morTality and time to Extubation in Patients with COVID-19 Requiring mechanical ventilation Meta-Trial (CHARTER-MT) is a prospective collaborative individual patient data analysis of randomised…
- Trial name
- CHARTER-MT (NCT04545541)
- Testing
- Nebulised unfractionated heparin (UFH)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Australian National University
Patients With Moderate to Severe Pain Requiring Analgesic Medications
Observation and Study on the Application of Different Analgesic Regimens in Critically Ill Patients Without Mechanical Ventilation
Pain management is a common treatment measure in the Intensive Care Unit (ICU). Due to their underlying diseases and invasive treatments, patients often experience discomfort and pain, leading to agitation, unplanned extubation…
- Trial name
- NCT07031453
- Volunteers
- 80 people
- Sponsor
- Peking University People's Hospital
Respiratory Insufficiency Requiring Mechanical Ventilation
Registry for Automated Mechanical VEntilation in Adults
The aim of the here proposed study is to assess safety, performance and provide real world evidence (RWE) of the Hamilton Medical AG automated mechanical ventilation software packages in consecutive critically ill patients…
- Trial name
- RAVE (NCT06655805)
- Testing
- Non-invasive ventilation, Invasive mechanical ventilation, high-flow nasal oxygen
- Where
- 4 sites in Switzerland
- Volunteers
- 1,000 people
- Sponsor
- Hamilton Medical AG
Ventilator Weaning, Mechanical Ventilation
Comparison of Diaphragm Ultrasound and RSBI for Predicting Weaning Success in Mechanically Ventilated ICU Patients
The goal of this observational study is to evaluate the predictive value of diaphragmatic ultrasound compared to the Rapid Shallow Breathing Index (RSBI) in determining weaning success among mechanically ventilated patients in…
- Conditions
- Ventilator Weaning, Mechanical Ventilation, Respiratory Insufficiency Requiring Mechanical Ventilation, Weaning From Mechanical Ventilation
- Trial name
- NCT07120438
- Volunteers
- 55 people
- Sponsor
- Gadjah Mada University
Respiratory Mechanics, Monitoring, Physiologic
Dynamic Non-invasive Monitoring of Inspiratory Effort
This prospective, observational cohort study aims to evaluate whether the dynamic monitoring of a patient's breathing effort can predict successful liberation from invasive mechanical ventilation.
- Conditions
- Respiratory Mechanics, Monitoring, Physiologic, Respiratory Insufficiency Requiring Mechanical Ventilation, Critical Illness
- Trial name
- NCT07839949
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears