Clinical trials: Resuscitations
Cardiopulmonary Resuscitation
Prognostic Indicators of Survival Following Cardiopulmonary Resuscitation in Patients With Cardiac Arrest
Cardiopulmonary resuscitation (CPR) occurs approximately 200,000 times/yr in hospitals in the UnitedStates, with 18% of patients surviving to discharge.
- Trial name
- NCT03597425
- Testing
- Cardiopulmonary resuscitation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Cardiac Arrest
Evaluation of the Quality of Cardio-Pulmonary Resuscitation (CPR) in Cardiac Arrest Patients
The prognosis of cardiac arrest patients is generally poor. Recent studies have showed that the high quality of CPR increases the survival after cardiac arrest.
- Trial name
- NCT00951704
- Where
- 2 sites in Finland
- Volunteers
- 1,000 people
- Sponsor
- Tampere University Hospital
Septic Shock
Protocolised Early De-Resuscitation in Septic Shock (REDUCE)
Background: Recent studies have questioned the safety of current fluid resuscitation strategies in patients with septic shock as prospective and observational data suggesting that the resulting fluid overload is associated with…
- Trial name
- REDUCE (NCT04931485)
- Testing
- Fluid management according to the REDUCE Fluid Protocol, Standard of care
- Where
- 4 sites in Switzerland
- Volunteers
- 170 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Resuscitation
Prevalence Study : Elderly Patients and Rehabilitation in ICU. Impact of Frailty.
Study design. The study FRAGIREA is a multicentric prevalence study on the frequency of frailty among elderly patients and the quality of management.
- Trial name
- FRAGIREA (NCT03326635)
- Testing
- Frailty in elderly (≥70 y) patients in ICU
- Where
- 37 sites in France, Mayotte
- Volunteers
- 527 people
- Sponsor
- Hospices Civils de Lyon
Mobile App Use in Resuscitation
A Mobile App For Drug Dosage Calculation In The Context Of Pediatric And Adult Resuscitation: A Cross-Over Randomized Controlled Trial
The purpose of this study is to investigate whether the use of the EZResus app by physicians and nurses reduces medication errors in simulated adult and pediatric resuscitation scenarios compared to the use of standard protocols.
- Trial name
- NCT06804915
- Testing
- simulation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Université de Sherbrooke
Terminal Illness, Heart Arrest
End-of-life Practices in 2019 vs. 2014
In 2014, the authors conducted a survey of key opinion leaders on ethical resuscitation practices in 31 European Countries. The authors administered a comprehensive questionnaire to 1-2 "experts" from each country…
- Conditions
- Terminal Illness, Heart Arrest, Ethics, Narrative
- Trial name
- NCT04078815
- Where
- 2 sites in Belgium, Greece
- Volunteers
- 84 people
- Sponsor
- University of Athens
Cardiac Arrest (CA)
Which Position Is Better For CPR In OHCA Patients?
Use Transesophageal ultrasound in OHCA patients to identify the proper CPR position
- Trial name
- NCT07002775
- Testing
- Transesophageal ultrasound
- Where
- 2 sites in Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Ventilation During Resuscitation
Mouth-to-mouth Ventilation Efficiency Through Breathable Self-sterilizing Respirator During BLS in COVID-19 Pandemic
Complex practical BLS training have been stopped all over the world due to COVID-19 pandemic in 2020. While launching the new Simulation Centre at Medical Faculty of Masaryk University in Brno, Czech Republic, teachers and…
- Trial name
- MOVERESP (NCT04867265)
- Testing
- Mout-to-mouth ventilation, Mout-to-mouth ventilation with quantitative analysis
- Where
- Czechia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
Cardiac Arrest
Comparison of the Quality of CPR by Professional Helpers (Emergency Physicians / Paramedics) During Flights
Investigation of the influence of narrowness and unusual circumstances on the CPR-quality
- Trial name
- flights (NCT02002481)
- Testing
- transport
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital of Cologne
Acute Respiratory Distress Syndrome (ARDS)
Multicentric, Randomized Study to Assess Safety and Efficacy of Centhaquine in Patients With ARDS
Acute respiratory distress syndrome (ARDS) is a life-threatening condition with a diffuse, inflammatory form of lung injury, causing pulmonary infiltration and respiratory failure leading to poor oxygenation.
- Trial name
- NCT05241067
- Testing
- Normal Saline, Centhaquine
- Volunteers
- 80 people
- Sponsor
- Pharmazz, Inc.
Critical Illness, Fluid Therapy
Intravenous Fluid Practices in Turkish Intensive Care Units (TR-FLUID)
Intravenous (IV) fluids-fluids given directly into a vein-are among the most common treatments used in intensive care units (ICUs).
- Conditions
- Critical Illness, Fluid Therapy, Practices
- Trial name
- NCT07649694
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Ondokuz Mayıs University
Critically Ill Patients, Septic Shock
Vexus-guided Fluid Management in Patients With Septic Shock After the Resuscitation Phase
It is well recognized the association between fluid volume administered and positive fluid balance with adverse outcomes . Active fluid removal is widely practiced in an attempt to mitigate this potential damage.
- Trial name
- VEXUS (NCT06227702)
- Testing
- Fluid management according to Venous Excess Ultrasound (VExUS) Score
- Volunteers
- 200 people
- Sponsor
- Federal University of São Paulo
Hospitalization in a Post-Resuscitation Rehabilitation Care Units
Characteristics and Evolution of Hospitalized Patients in Post-Resuscitation Rehabilitation Care Units (SRPR)
Non-interventional cohort study (on data), prospective national multicenter. Inclusion of patients as they enter in a post-intensive care rehabilitation unit (SRPR) .
- Trial name
- Cohorte-SRPR (NCT03768700)
- Testing
- Data gathering
- Where
- 10 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiopulmonary Resuscitation
Quality of Cardiopulmonary Resuscitation Guided by AED vs Telephone-assistance
The aim of this research is to evaluate and to compare the quality of cardiopulmonary resuscitation (CPR) among untrained laypeople under two different scenarios: automated external defibrillator (AED) guided CPR or…
- Trial name
- QRCP (NCT03771911)
- Testing
- AED, Telephone
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bionorte
Shock, Dyspnea
AFrican Resuscitation Ultrasound In Critically-ill Adults
The proposed study is a prospective cohort study in which a select group of emergency physicians at Komfo Anokye Teaching Hospital (KATH) in Ghana will be trained in cardiopulmonary ultrasound (CPUS).
- Trial name
- AFRICA (NCT02794909)
- Testing
- Cardiopulmonary ultrasound exam
- Where
- Ghana
- Volunteers
- 180 people
- Sponsor
- Rockefeller Oteng
Cardiac Arrest, Cardiopulmonary Resuscitation
Circulation Improving Resuscitation Care (CIRC)
During resuscitation of out of hospital cardiac arrest patients the use of a mechanical chest compression device Autopulse will improve survival compared to manual compressions.
- Trial name
- CIRC (NCT00597207)
- Testing
- AutoPulse, Manual
- Where
- 5 sites in United States, Austria and 1 more
- Volunteers
- 4,231 people
- Sponsor
- Zoll Medical Corporation
Pancreas and Hepatobiliary Cancer Patients
Cardiopulmonary Resuscitation (CPR) Video to Enhance Advance Care Planning in Advanced Upper Gastrointestinal Cancer Patients
Advance care planning involves thinking about choices if the patient becomes sick, and is important for everyone. It does not matter if the patients are ill or healthy.
- Trial name
- NCT01105806
- Testing
- (CPR) video and questionnaires, cardiopulmonary resuscitation (CPR) narrative script and questionnaires
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Out-Of-Hospital Cardiac Arrest
Selective Cerebral Hypothermia Trial - Under Extracorporeal Cardiopulmonary Resuscitation (SHOT-ECPR)
The study is designed as a pilot, open-label study to investigate the feasibility and safety of selective cerebral hypothermia in OHCA patients receiving ECPR.
- Trial name
- NCT03345706
- Testing
- Selective cerebral hypothermia, Regular hypothermia
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Respiratory Distress Syndrome in Premature Infants, Very Low Birth Weight Baby
Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal Resuscitation
This study hopes to determine whether nitric oxide along with oxygen during the first 20 minutes of life in infants needing help with breathing will reduce the percentage and total exposure to oxygen during that time frame.
- Trial name
- iNO (NCT01220687)
- Testing
- iNO, Nitrogen
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of Oklahoma
Sepsis, Severe Sepsis
The AVERT Sepsis Investigation
The overall objective of this study is to utilize heart rate variability and respiratory rate variability in patients with sepsis to predict clinical deterioration and death. Our specific objectives are: 1.
- Trial name
- AVERT (NCT01968746)
- Where
- 5 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Christiana Care Health Services
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