Clinical trials: Resuscitations
Hemorrhagic Shock, Pediatric Trauma
Effect of Resuscitation on Gastric Emptying Using POCUS in Pediatric Trauma Patients
Pediatric trauma often leads to hemorrhagic shock, which reduces blood flow to the digestive tract and delays gastric emptying. This delay can cause fluid and food to remain in the stomach, increasing the risk of pulmonary…
- Conditions
- Hemorrhagic Shock, Pediatric Trauma, Delayed Gastric Emptying, Gastric Dysmotility
- Trial name
- NCT07810907
- Volunteers
- 50 people
- Sponsor
- Assiut University
Fluid Resuscitation, Fluid Responsiveness Predictability
Evaluation of the Variation of the Sub-pulmonary Velocity-time Integral to Predict Fluid Responsiveness
Fluid administration is the first-line treatment in hypovolemic states in critically ill patients. Prediction of fluid responsiveness is possible with echocardiography by assessing the variation of the sub-aortic velocity-time…
- Trial name
- NCT07202637
- Testing
- Fluid bolus administration
- Where
- 2 sites in France
- Volunteers
- 205 people
- Sponsor
- Hospital Nord
Resuscitation
Mobile Virtual Simulation Training in Essential Newborn Care for Healthcare Workers in Low and Middle Income Countries
Intrapartum asphyxia and prematurity are the leading causes of neonatal mortality in low and middle income countries. Neonatal resuscitation training reduces asphyxia-related newborn mortality and morbidity, but in the absence of…
- Trial name
- NCT05551312
- Testing
- Virtual Essential Newborn Care (vENC) training
- Where
- Nigeria
- Volunteers
- 150 people
- Sponsor
- University of Washington
Echocardiography, Transesophageal, In-hospital Cardiac Arrest
RescueTEE for In-hospital Cardiac Arrest (ReTEECA Trial)
ReTEECA Trial. Rescue TransEsophageal Echocardiography for In-Hospital Cardiac Arrest. This trial is aimed at studying the utility and interventional outcomes of rescue transesophageal echocardiography (RescueTEE) to aid in…
- Conditions
- Echocardiography, Transesophageal, In-hospital Cardiac Arrest, Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
- Trial name
- ReTEECA (NCT04220619)
- Testing
- Tranesophageal Echocardiography
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Resuscitation, Prehospital Emergency
CPR Quality in Via Ferrata Rescues
This study evaluates the effectiveness of CPR during via ferrata rescues, focusing on response quality and outcomes in challenging outdoor settings.
- Trial name
- NCT06070077
- Testing
- Chest compressions
- Where
- Czechia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Zdravotnicka Zachranna Sluzba Karlovarskeho Kraje, P.O.
Cardiac Arrest, Out-Of-Hospital
Gathering Evidence on Best Practices for Lay Rescuer CPR Training
The goal of this prospective trial is to compare CPR skill and attitudes in lay rescuers. The main question[s] it aims to answer are: What is the optimal training timing, duration, and frequency for lay rescuers that leads to CPR…
- Trial name
- NCT05908500
- Testing
- CPR Training, CPR Manikin Type
- Where
- United States
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Septic Shock
Septic Shock Hemodynamic Respond to Volume Resuscitation Versus Vasopressor Administration
The goal of this observational study is to learn about the change of hemodynamic response from intravenous fluid versus medical (vasopressor) resuscitation by echocardiogram in septic shock patient.
- Trial name
- ECHO-VEVA (NCT07438301)
- Testing
- Echocardiogram
- Where
- Thailand
- Volunteers
- 180 people
- Sponsor
- Mahidol University
Fetal Distress, Fetal Hypoxia
Maternal Oxygen Supplementation for Intrauterine Resuscitation
More than 80% of the 3 million women who labor and deliver each year in the United States undergo continuous electronic fetal monitoring (EFM) during labor in order to fetal hypoxia and prevent the transition to acidemia…
- Conditions
- Fetal Distress, Fetal Hypoxia, Labor and Delivery Complication
- Trial name
- MOXY (NCT05681624)
- Testing
- Maternal oxygen supplementation, Room air
- Where
- United States
- Volunteers
- 2,252 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cardiopulmonary Resuscitation, Hand Position
Optimum Hand Position During Cardiopulmonary Resuscitation
The almost evidences of the optimal hand position during compression had been based on chest computed tomography (CT) or chest plain films of patients for investigating the effective location for compressing the left ventricle of…
- Trial name
- NCT02715180
- Testing
- low dose chest computed tomography
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Cardiac Arrest, Sudden
Impact of the Organization of the First Responders in the Remote Areas on Cardiac Arrest Victim Survival
Emergency medical services (EMS) provide emergency care not only in the urban but also in the remote areas which could be up to 40 minutes from the EMS station.
- Trial name
- NCT04485390
- Testing
- Basic life support witn use of an AED before EMS
- Volunteers
- 150 people
- Sponsor
- University Medical Centre Maribor
Acute Kidney Injury Due to Sepsis
Hemodynamic Resuscitation Guided by Non-Invasive Mean Systemic Filling Pressure to Prevent Acute Kidney Injury in Septic Shock
The goal of this clinical trial is to evaluate the efficacy of a hemodynamic resuscitation protocol guided by the Venous Return Gradient (Pmsf - CVP), measured via the non-invasive arm cuff technique, in reducing the incidence of…
- Trial name
- NCT07481097
- Testing
- Hemodynamic measurements during reduction in Norepinephrine and fluid boli.
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cardiac Arrest
Improving the Quality of Cardiopulmonary Resuscitation (CPR) During Pediatric Cardiac Arrest
Our project aims to improve the delivery and assessment of cardiopulmonary resuscitation (CPR) during pediatric cardiac arrest by introducing 2 novel approaches: 1.
- Trial name
- QCPR (NCT02075450)
- Testing
- CPRcard, Just in Time Video
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Shock, Traumatic
Hypertonic Resuscitation Following Traumatic Injury
The purpose of this study is to determine if hypertonic saline with and without dextran can improve overall survival in victims of trauma with shock.
- Trial name
- NCT00316017
- Testing
- 7.5% hypertonic saline/6% Dextran-70 (HSD), 7.5% hypertonic saline (HS), 0.9% normal saline
- Where
- 10 sites in United States, Canada
- Volunteers
- 895 people
- Sponsor
- University of Washington
To Evaluate the Impact of a Basic Resuscitation Training Program on the Related Knowledge and Practices of CPR Among Private Home Nurses in Qatar
Impact of VAK & Kolb-Based Education on CPR Knowledge & Skills Among Private Home Nurses in Qatar
Out-of-hospital cardiac arrest (OHCA) is a significant global health challenge, responsible for a substantial proportion of deaths worldwide.
- Trial name
- NCT06865690
- Testing
- Eductional training program
- Where
- Qatar
- Volunteers
- 134 people
- Sponsor
- Assiut University
Heart Arrest, Seizures
Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac Arrest
Non-convulsive seizures (NCS) following cardiac arrest are common and are associated with worse neurologic outcomes and increased mortality. More prolonged seizures (status epilepticus) are associated with worse outcomes.
- Trial name
- NCT02458820
- Testing
- DSA EEG
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital of Philadelphia
Out-of-Hospital Cardiac Arrest
Reduction of Oxygen After Cardiac Arrest
The Reduction of oxygen after cardiac arrest (EXACT) is a multi-centre, randomised, controlled trial (RCT) to determine whether reducing oxygen administration to target an oxygen saturation of 90-94%, compared to 98-100%, as soon…
- Trial name
- EXACT (NCT03138005)
- Testing
- target SpO2 98-100%, target SpO2 90-94%
- Where
- 21 sites in Australia
- Volunteers
- 428 people
- Sponsor
- Monash University
Infant Showing No Response to Resuscitation
MedNav: Improving Neonatal Life Support (NLS)
This study was designed to evaluate if MedNav impacts the ability of novice resuscitators to perform Neonatal Life Support (NLS) in the simulated environment, and if this ability is maintained after a 7 week period.
- Trial name
- NCT02932683
- Testing
- MedNav
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Out-of-Hospital Cardiac Arrest
REBOA in Out-of-hospital Cardiac Arrest
Unexpected cardiac arrest is a frequent and devastating event with a high mortality and morbidity. Half of the patients who survive to ICU admission ultimately die because of hypoxic-ischemic encephalopathy.
- Trial name
- NCT04373122
- Testing
- REBOA
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Severe Thermal Injury, Greater Than 20% TBSA
Vitamin C for Severe Thermal Injuries
Animal and human data have supported the notion that administration of large doses of Vitamin C has beneficial effects on those subjects suffering from large burns.
- Trial name
- NCT01587261
- Testing
- Vitamin C
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Neonatal Resuscitation, Airway Management
Success of Laryngeal Mask Airway (LMA) Insertion During Continuous Chest Compressions in Neonatal Resuscitation: A Randomized Crossover Simulation Study
The purpose of this study is to evaluate the time required for laryngeal mask airway (LMA) insertion, first-attempt success rates, and airway sealing quality (air leak) during neonatal resuscitation with and without interrupting…
- Conditions
- Neonatal Resuscitation, Airway Management, Asphyxia Neonatorum, Cardiopulmonary Resuscitation (CPR)
- Trial name
- NCT07681960
- Testing
- Size 1 ProSeal™ LMA
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
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