Clinical trials: Resuscitations
Cardiac Arrest With Successful Resuscitation, Mechanical Ventilation
Study of Ventilator Associated Event During Intensive Care After Resuscitated Cardiac Arrest.
The aim is to describe the incidence, characteristics, risk factors and outcome of complications acquired under mechanical ventilation (called ventilator-associated events) according to the new CDC criteria, in a population of…
- Trial name
- VAE-ACR (NCT06466980)
- Testing
- Ventilator associated event
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Sud Francilien
Cardiac Arrest, Out-Of-Hospital Cardiac Arrest
Initial Double Sequential External Defibrillation in Out of Hospital Cardiac Arrest
Double Sequential External Defibrillation (DSED) represents an alternative treatment of refractory ventricular fibrillation (rVF) in out-of-hospital cardiac arrest (OHCA).
- Conditions
- Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Ventricular Fibrillation
- Trial name
- DUALDEFIB (NCT06672159)
- Testing
- Two defibrillators, One defibrillator
- Where
- Norway
- Volunteers
- 356 people
- Sponsor
- St. Olavs Hospital
Pregnancy, Cardiac Arrest
Influence of the Method of Alleviation of Aorto-Caval Compression on the Trans-Hepatic Ultrasound-Assessed Inferior Vena Cava Diameter In Pregnant Patients
Cardiac arrest during pregnancy is rare but may result in poor maternal and fetal outcome. Because of its rare occurrence and ethical issues this topic is not very well studied and many questions pertaining to maternal…
- Trial name
- NCT01982513
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Cardiac Arrest
Pediatric Resuscitation With Feedback Devices
The aim of this study was to compare four different CPR feedback devices to standard BLS in terms of the quality of single rescuer pediatric resuscitation.
- Trial name
- CPR_NURSE (NCT02294721)
- Testing
- Standard BLS, The CPREazy, TrueCPR
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Cardiac Arrest, Extracorporeal Membrane Oxygenation
Hydrogen's Feasibility and Safety as a Therapy in ECPR
The purpose of this project is to test the feasibility and safety of inhaled hydrogen gas (H2) administration as a rescue therapy during cardiac arrest requiring extracorporeal cardiopulmonary resuscitation (ECPR, i.e.
- Conditions
- Cardiac Arrest, Extracorporeal Membrane Oxygenation, Reperfusion Injury
- Trial name
- HydrogenFAST (NCT05574296)
- Testing
- Hydrogen, Usual care
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Out-Of-Hospital Cardiac Arrest
EXecution of Trans-Esophagus Echo Cardiogram in CardioPulmonary Resuscitation for Patients With Out-of-hospital Cardiac Arrest
The purpose of this single center, randomized clinical control trial is to determine that changing chest compression site during cardiopulmonary resuscitation according to the examination of the TEE could increase the level of…
- Trial name
- EXECT_CPR (NCT05907460)
- Testing
- transesophageal echocardiography examination during cardiopulmonary resuscitation
- Where
- Taiwan
- Volunteers
- 132 people
- Sponsor
- Far Eastern Memorial Hospital
Basic Life Support Training Course, Cardiopulmonary Resuscitation (CPR)
Serious Game vs Traditional BLS Training in Adolescents
This randomized controlled trial aimed to compare the effects of a serious video game and traditional training on adolescents' basic life support (BLS) knowledge and skills.
- Trial name
- NCT07286708
- Testing
- Lifesaver Video Game CPR Training, Traditional Instructor-Led CPR Training
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Burcu SELVI CALSIKAN
Out-of-hospital Cardiac Arrest (OHCA)
Resuscitation Enhancement to Avoid Rearrest Through Evidence-based Strategies in Prehospital Post-resuscitation Care
Out-of-hospital cardiac arrest (OHCA) remains a leading global emergency condition with low survival to hospital discharge despite advances in cardiopulmonary resuscitation.
- Trial name
- RE-ARREST (NCT07239908)
- Testing
- Prehospital post cardiac arrest care protocol
- Where
- Thailand
- Volunteers
- 318 people
- Sponsor
- Siriraj Hospital
Sepsis, Severe, Sepsis
Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock
The sublingual microcirculation is impaired in sepsis and septic shock. Sidestream dark field imaging technology has been developed into a clinical tool to help the clinician assess the microcirculation at the bedside.
- Conditions
- Sepsis, Severe, Sepsis, Septic Shock
- Trial name
- NCT05357339
- Testing
- 20% Albumin, Crystalloid
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- Rachael Cusack
Hypothermia, Heart Arrest
Clinical and Economical Interest of Endovascular Cooling in the Management of Cardiac Arrest (ICEREA Study)
According to international guidelines, mild therapeutic hypothermia is recommended for resuscitated patients after cardiac arrest due to ventricular fibrillation.
- Trial name
- NCT00392639
- Testing
- Comparison of 2 cooling procedures
- Where
- France
- Volunteers
- 389 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy, Childbirth and the Puerperium, Resuscitation
Oronasopharyngeal Suction Versus Simple Nose and Mouth Wiping in Term Newborns
Until recently, bulb or catheter oronasopharyngeal suctioning (ONPS) of all the infants, including vigorous infants in the delivery room, has been featured as a standard of newborn care.
- Trial name
- TermWIPE (NCT01197807)
- Testing
- Bulb Suctioning, Wiping
- Where
- United States
- Volunteers
- 506 people
- Sponsor
- University of Alabama at Birmingham
Opioid Use, Opioid-Related Disorders
Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER)
Among people at risk of opioid overdose and receiving care in an academic emergency department, family practice, opioid substitution clinic or general inpatient units, does brief opioid overdose resuscitation training and…
- Conditions
- Opioid Use, Opioid-Related Disorders, Opioid Withdrawal, Opioid Overdose
- Trial name
- SOONER (NCT04740099)
- Testing
- SOONER Video & Kit, Standard of Care
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Premature Birth
Prophylactic DR-CPAP on Late Preterm Infants Born by C-section: an RCT
A Pragmatic Randomized Controlled Pilot Trial to Evaluate the Impact of Early Prophylactic Continuous Positive Airway Pressure with or without Supplemental Oxygen in Spontaneously Breathing Late Preterm Newborn Infants Born by…
- Trial name
- PLANT (NCT05204719)
- Testing
- Prophylactic Delivery Room Continuous Positive Airway Pressure
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Hospitalization in a Post-Resuscitation Rehabilitation Care Units
Characteristics and Evolution of Hospitalized Patients in Post-Resuscitation Rehabilitation Care Units (SRPR)
Non-interventional cohort study (on data), prospective national multicenter. Inclusion of patients as they enter in a post-intensive care rehabilitation unit (SRPR) .
- Trial name
- Cohorte-SRPR (NCT03768700)
- Testing
- Data gathering
- Where
- 10 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sudden Cardiac Arrest
HS Students Mandatory Universal Student Instruction in CPR Appraised Learning- Is the Mandate Working?
This study will help to provide better input to state health and education departments to improve the processes for CPR education.
- Trial name
- NCT04493970
- Testing
- High School Students Survey
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Shock, Septic
Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study
The objective of this pilot study is to assess overall feasibility prior to embarking on a larger randomized pragmatic trial comparing the clinical effectiveness of fluid resuscitation with NS versus LR for pediatric patients…
- Trial name
- PRoMPT BOLUS (NCT03340805)
- Testing
- Lactated Ringer, Normal saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Hospital of Philadelphia
Abdominal Hypertension, Abdominal Compartment Syndrome
Colloids in Severe Trauma
Background: Fluid resuscitation is a cornerstone of the initial management of the critically injured trauma patient yet there are numerous controversies surrounding this very common practice.
- Conditions
- Abdominal Hypertension, Abdominal Compartment Syndrome, Severe Trauma
- Trial name
- CIST (NCT00890383)
- Testing
- tetrastarch (Voluven)
- Where
- 2 sites in Philippines
- Volunteers
- 50 people
- Sponsor
- University of the Philippines
Norepinephrine, Hemorrhagic Shock
Norepinephrine in Preperiod of Hypotensive Resuscitation in Hemorrhagic Shock
The aim of this work was to investigate the effects of low dose of norepinephrine in preperiod of hypotensive resuscitation in hemorrhagic shock.
- Conditions
- Norepinephrine, Hemorrhagic Shock, Hypotensive Resuscitation
- Trial name
- NCT06311903
- Testing
- Low dose of Norepinephrine (NE), High dose of Norepinephrine (NE)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Tanta University
Lung Injury, Preterm Birth
Positive End-Expiratory Pressure (PEEP) Levels During Resuscitation of Preterm Infants at Birth (The POLAR Trial).
Premature babies often need help immediately after birth to open their lungs to air, start breathing and keep their hearts beating.
- Trial name
- POLAR (NCT04372953)
- Testing
- Positive End-Expiratory Pressure (PEEP)
- Where
- 27 sites in United States, Australia and 5 more
- Volunteers
- 906 people
- Sponsor
- Murdoch Childrens Research Institute
Hemorrhagic Shock, Traumatic Injury
Type O Whole Blood and Assessment of Age During Prehospital Resuscitation Trial
Open label, multi-center, pre-hospital randomized trial utilizing 10 level-1 trauma centers designed to determine the efficacy and safety of low titer whole blood resuscitation as compared to standard of care resuscitation in…
- Trial name
- TOWAR (NCT04684719)
- Testing
- low titer whole blood, Standard Care
- Where
- 10 sites in United States
- Volunteers
- 1,020 people
- Sponsor
- Jason Sperry
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