Clinical trials: Reward
Health Promotion, Wellness Programs
Assessing the Impact of myHealth Rewards Enrollment Emails
The purpose of the study is to evaluate, prospectively, the potential impact of different email message conditions (no email, standard promotional email, social norms, and loss framing) on enrollment in a wellness program…
- Trial name
- NCT03965754
- Testing
- Social norms, Loss framing, Email reminder
- Where
- United States
- Volunteers
- 5,697 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Vagus Nerve Stimulation in Reward Learning
Pulsed tVNS Protocol and Reinforcement Learning
The aim of this study is to investigate the potential of a phasic taVNS stimulation protocol for reinforcement learning. The investigators will disentangle its effects on learning actions and outcomes through the administration…
- Trial name
- NCT06205108
- Testing
- taVNS stimulation
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Interactive Condition (HAPA-I: Group 1), Non-interactive Condition (HAPA-NI: Group 2)
A Boost of Health: Effectiveness of a Personalized Communication Intervention to Increase Daily Fruit and Vegetable Intake
This study aims to evaluate the efficacy of a healthy diet promotion intervention focused on increasing fruit and vegetable consumption.
- Conditions
- Interactive Condition (HAPA-I: Group 1), Non-interactive Condition (HAPA-NI: Group 2), Non-communication Condition (No Comm: Group 3)
- Trial name
- NCT07581847
- Testing
- Interactive communication, Non-interactive Communication, Self-monitoring
- Where
- Italy
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Marco D'Addario
Eating Disorders, Eating Behavior
Food Reward Circuit Change by Orthodontics
It has been described in obese individuals in which decreased basal metabolism as well as dopaminergic changes in the prefrontal cortex and striatum parallels the increased activation of reward brain regions in response to…
- Conditions
- Eating Disorders, Eating Behavior, Eating Habit, Orthodontic Appliance Complication
- Trial name
- DTI (NCT05026411)
- Testing
- T 0 Diffusion Tensor MR, T 1 Diffusion Tensor MR, T 2 Diffusion Tensor MR
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Major Depressive Disorder
tVNS Effects on Motivation in Depression
Attaining goals or rewards commonly entails response costs. In light of cost and benefits, how do participants decide what effort should be put in to give it a shot? Figuratively, you may "go with your gut", but the literal…
- Trial name
- NCT05120336
- Testing
- transcutaneous vagus nerve stimulation
- Where
- Germany
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Alcohol Use Disorders
Learning and Relapse Risk in Alcohol Dependence
The aim of this project is to assess which behavioral and neuroimaging alterations associated with reward- based learning predict relapse in alcohol- dependent patients within a follow- up period of 12 months.
- Trial name
- LeAD (NCT01679145)
- Where
- 3 sites in Germany
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Tobacco Use, Cigar Smoking
The Effect of Sweet Flavoring on the Rewarding and Reinforcing Value of Cigarillo Use Among Young Adults
This within-subjects study aims to evaluate the subjective rewarding value, the relative reinforcing value, and the absolute reinforcing value of sweet flavored cigarillos across three separate laboratory visits among 86 young…
- Trial name
- FLAV (NCT05092919)
- Testing
- Flavor
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cirrhosis, Food Preferences
Feeding Behavior and Taste Sensitivity Before and After Liver or Renal Transplantation
This study evaluates the influence of the taste sensitivity, of food preferences and of the reward system on the energetic balance before and after liver transplantation in cirrhotic patients and after kidney transplantation in…
- Conditions
- Cirrhosis, Food Preferences, Taste Disorders, Protein-Energy Malnutrition
- Trial name
- GREFFE (NCT02931812)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Burgundy
Alcohol Drinking
Nicotinic Receptor Genetic Variation and Alcohol Reward
Background: People with the brain disease AUD (alcohol use disorder) have a serious problem with drinking. Researchers want to study how different people react to alcohol, and how genes affect this.
- Trial name
- NCT03294460
- Testing
- Alcohol (Oral), Alcohol (IV), Alcohol (Ethanol)
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Addiction
Effects of Repetitive tDCS on ad Libitum Smoking Behavior: EMA and EEG Study
Bilateral (left cathodal/ right anodal) transcranial Direct Current Stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) seems to reduce craving and to increase the time till smoking the first cigarette after the…
- Trial name
- NCT03027687
- Testing
- tDCS
- Where
- Netherlands
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Alcohol Use Disorder (AUD), Alcoholism
Assessing Habitual, Goal-Directed, and Pavlovian Influences in Alcohol Use Disorder
The first aim of this study is to establish the role of maladaptive reliance on habits for impaired control in addiction, employing a novel task - the Action-Sequence-Task (AST), which assesses interference between habitual and…
- Conditions
- Alcohol Use Disorder (AUD), Alcoholism, Substance Use Disorders
- Trial name
- ReCoDe (NCT06701500)
- Testing
- Pavlovian-to-instrumental transfer (PIT) paradigm, Action Sequence Task (AST), Basic psychological assessment (interview)
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Performance vs. Effort Rewards
Engaging Mental Effort: Process- and Person-Based Reward Experiences, Effort Reinforcement Intervention, and Cascading Effects on Challenging Tasks
Brief Summary: The goal of this clinical trial is to investigate the influences of children's prior experiences with rewards following successes at school and interventions aimed at influencing children's preferences for…
- Trial name
- RoSE2025 (NCT07557732)
- Testing
- Performance Rewards, Effort Rewards
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of California, Davis