Clinical trials: Right Heart Failure Due to Pulmonary Hypertension
Eccentric Exercise Training
Eccentric Cycling Exercise During Pulmonary Rehabilitation in Patients With Cardiopulmonary Diseases
Eccentric cycling exercise (ECC) allows training at low metabolic costs and may therefore be valuable for patients with pulmonary vascular disease (PVD).
- Trial name
- NCT07042750
- Testing
- Eccentric cycling exercise, Standard Care Arm
- Where
- 2 sites in Switzerland
- Volunteers
- 22 people
- Sponsor
- Silvia Ulrich Somaini
Cardiopulmonary Disease
Effects of Secondhand Smoke on Flight Attendant Health
This is a study on a population of flight attendants who were exposed to occupational secondhand tobacco smoke (SHS). This research will examine associations between flight attendant SHS exposure and development of respiratory…
- Trial name
- FAMRI (NCT01639235)
- Where
- United States
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sickle Cell Anemia
Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia
The purpose of this study is to use comprehensive exercise testing to examine longitudinal changes in exercise capacity over a 2 year period in children and young adults with sickle cell anemia.
- Trial name
- NCT01558076
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Cardiac Disease, Pulmonary Disease
Cardiopulmonary Outpatient Rehabilitation Using Mobile Technology
This is a randomized controlled trial of the feasibility and utility of implementing a smartphone application (MVN) to maintain compliance with a Heart Healthy lifestyle after discharge from a cardiac outpatient rehabilitation…
- Conditions
- Cardiac Disease, Pulmonary Disease, Cardiopulmonary Disease
- Trial name
- NCT02671669
- Testing
- Usual Care, Movn application (MVN)
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- NYU Langone Health
Pulmonary Embolism With Acute Cor Pulmonale
Polish Multicenter PERTs PE Outcomes Registry
Pulmonary embolism (PE) is the third leading cause of cardiovascular mortality. The Pulmonary Embolism Response Team (PERT) concept offers a rapid and multidisciplinary approach focused on improving outcomes for patients with PE.
- Trial name
- PolPERTs (NCT04879069)
- Where
- Poland
- Volunteers
- 10,000 people
- Sponsor
- Poznan University of Medical Sciences
Cardiopulmonary Disease, Fluid Overload
Fluid Status and Body Composition Analysis by Bioelectrical Impedance in Patients After Cardiac Surgery (FLUBIACS)
Evaluation of fluid status in cardiac surgery patients using bioelectrical impedance and its impact on postoperative morbidity and mortality
- Trial name
- FLUBIACS (NCT06498375)
- Testing
- Bioelectrical impedance
- Where
- Slovenia
- Volunteers
- 150 people
- Sponsor
- University Medical Centre Ljubljana
ARDS (Acute Respiratory Distress Syndrome), Acute Cor Pulmonale
Acute CorPulmonale and ARDS Circulation Protection China Study China (ACPC)
The investigators established a national cohort of Chinese ARDS with Acute CorPulmonale to enable prospective observational studies. The goals are the following.
- Trial name
- NCT03827863
- Testing
- TTE
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Pulmonary Embolism With Acute Cor Pulmonale
Catheter-directed Thrombectomy in High and Intermediate-high Risk Pulmonary Embolism
Pulmonary embolism is one of the leading causes of cardiovascular death. Pulmonary embolism may be life-threatening condition with an estimated 30-day mortality rate about 10-30%.
- Trial name
- CATH-PE (NCT04473560)
- Testing
- Catheter-directed thrombectomy
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Right Ventricular Dysfunction, Cardiopulmonary Diseases
Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0)
RIGHT-NET 2.0 is a multicenter observational study with a retrospective-prospective design that builds on the original RIGHT-NET study.
- Conditions
- Right Ventricular Dysfunction, Cardiopulmonary Diseases, Pulmonary Hypertension
- Trial name
- RIGHT-NET 2 (NCT07851610)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- IRCCS SYNLAB SDN
Cardiopulmonary Disease
SGA for TEE: Safe Alternative to Deep Sedation for Patients With High-risk Cardiopulmonary Disease.
Increasingly, transesophageal echos (TEEs) are being done on high risk patients. A TEE is a short procedure done with deep sedation, but poses an increased risk of apnea/ hypoxemia in those with pulmonary disease.
- Trial name
- SGA-TEE (NCT04939220)
- Testing
- TEE with SGA, TEE with Deep Sedation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Pulmonary Embolism, Pulmonary Embolism Without Mention of Acute Cor Pulmonale
NT-proBNP as a Tool for the Detection of Acute Pulmonary Artery Embolism (APE)
In patients with suspected APE (Acute Pulmonary Embolism) referred to the intensive care unit (ICU)after major surgery, serum NT-proBNP (N-terminal proBNP), Troponin-I and D-dimers were measured according to the standard hospital…
- Trial name
- NCT01633671
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- University of Ulm
Cardiac Disease, Respiratory Disease
Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)
Subjects will use the Gabi system on a daily basis for 3 months, each time the subject is resting or asleep. The Gabi system will recording the SpO2, pulse rate, respiratory rate and movements of the subject.
- Conditions
- Cardiac Disease, Respiratory Disease, Congenital Cardiac Defect, Cardiovascular Diseases
- Trial name
- BRIDGE (NCT05319236)
- Testing
- Gabi System
- Where
- 4 sites in United States, Belgium
- Volunteers
- 101 people
- Sponsor
- Gabi SmartCare
Acute Respiratory Distress Syndrome, Acute Cor Pulmonale
Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO
Recent data from large trials of high-frequency high frequency oscillation (HFO) without a cuff leak vs, lung-protective conventional ventialtion (CMV) failed to show any HFO-related benefit with respect to outcome.
- Trial name
- NCT02027129
- Testing
- High Frequency Oscillation
- Where
- Greece
- Volunteers
- 17 people
- Sponsor
- University of Athens
Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
Move With Air: Exercise Training Study
The purpose of this study is to explore the role of a stream of cool air to the face, through fan-to-face therapy, as a novel adjunct non-pharmacological therapy to enable symptomatic adults with cardiopulmonary disease to…
- Conditions
- Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease, Heart Failure
- Trial name
- NCT05646407
- Testing
- Honeywell HT-900 Turbo Force Air Circulator
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- McGill University
Acute Respiratory Distress Syndrome, Right Ventricular Dysfunction
Detection of Right Ventricular Dysfunction by 2D Strain During Acute Respiratory Distress Syndrom (ARDS)
Acute respiratory distress syndrome (ARDS) and mechanical ventilation can lead to right ventricular dysfunction and ultimately right ventricular failure by increasing pulmonary vascular resistances and pressure load.
- Conditions
- Acute Respiratory Distress Syndrome, Right Ventricular Dysfunction, Right Heart Failure, Acute Cor Pulmonale
- Trial name
- STRAIN (NCT01757522)
- Where
- France
- Volunteers
- 47 people
- Sponsor
- University Hospital, Grenoble
Cardiopulmonary Disease
Respiration Validation for CPM Device
This study is designed to be a clinical validation study to ready the CPM System for FDA 510(k) submission. This study will be conducted as a prospective non-randomized.
- Trial name
- NCT05445492
- Testing
- CPM Device
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Analog Device, Inc.
Covid19, Acute Cor Pulmonale
Cardiac Performance in Mechanically Ventilated COVID-19 Patients
Although COVID-19 affects primarily the respiratory system, several studies have shown evidence of cardiovascular alterations. Increased troponin levels were observed in a significant proportion of patients and this alteration…
- Conditions
- Covid19, Acute Cor Pulmonale, Cardiac Failure
- Trial name
- NCT04628195
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Pulmonary Hypertension, Right Heart Failure Due to Pulmonary Hypertension
Postural Changes During Right Heart Catheterization
Hemodynamic measurements obtained during pulmonary artery catheterization are essential for the diagnosis and classification of pulmonary hypertension.
- Trial name
- NCT03089164
- Testing
- Right heart catheterization
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF
The goal of this fully-remote randomized controlled trial is to test the efficacy of Mindful Steps in facilitating physical activity compared to usual standard of care among 136 patients with COPD and/or HF.
- Trial name
- NCT05934565
- Testing
- Mindful Steps
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- Beth Israel Deaconess Medical Center
Pulmonary Hypertension, Lung Disease
Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide
The purpose of this program is to evaluate the logistic issues and patient requirements for chronic pulsed INOmax delivery in ambulatory, home-care patients.
- Conditions
- Pulmonary Hypertension, Lung Disease, Sickle Cell Disease, Cardiac Transplant
- Trial name
- NCT00041574
- Testing
- Inhaled Nitric Oxide
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Mallinckrodt