Clinical trials: Risk Reduction
Pertussis
Assessing Contacts' Decision Making on Reducing the Risk of Pertussis Transmission to Newborns Through Immunisation
This study aims to establish an effective method to inform parents or close relatives of newborns about the risk of pertussis transmission to newborns and the advantages offered by the cocooning strategy (vaccinating those who…
- Trial name
- NCT01890447
- Testing
- Web-based survey questionnaire
- Where
- 9 sites in Italy, Spain
- Volunteers
- 676 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Pain, Opioid-Related Disorders
Transforming Opioid Prescribing in Primary Care
Prescription opioid misuse is a significant public health problem as well as a patient safety concern. Primary care providers are the leading prescribers of opioids for chronic pain, yet few providers follow standard practice…
- Trial name
- TOPCARE (NCT01909076)
- Testing
- Electronic decision support tools, Enhanced patient education materials, Nurse care management
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Nicotine Dependence, Tobacco Toxicity
Cigarette Harm Reduction With Electronic Cigarette Use
This is an observational, crossover study that will be examine use behaviors, chemical exposures, and biological effects of SREC compared to TC use in subjects confined to a research ward setting.
- Conditions
- Nicotine Dependence, Tobacco Toxicity, Nicotine Dependence, Cigarettes, Cardiovascular Risk Factor
- Trial name
- NIDA-SREC (NCT03473483)
- Testing
- SREC
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV Infections
HIV Prevention Within High-Risk Bulgarian and Hungarian Social Networks
This study will evaluate the effectiveness of peer-led HIV/sexually transmitted disease (STD)risk reduction educational counseling in reducing HIV risk behavior among the social networks of young men who have sex with men and…
- Trial name
- NCT00310973
- Testing
- Social Network Intervention
- Where
- 3 sites in Bulgaria, Hungary and 1 more
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Risk Reduction Behavior, Interpersonal Relations
A Community-health Worker Delivered HIV/STI Prevention Intervention for Internally Displaced Women in Leogane, Haiti
The investigators will develop, deliver and evaluate a solar powered tablet-based individual and group focused HIV/STI prevention intervention with internally displaced women in Leogane, Haiti.
- Conditions
- Risk Reduction Behavior, Interpersonal Relations, Mental Disorders
- Trial name
- FASY (NCT01492829)
- Testing
- individual and group-based, community health worker delivered
- Where
- Haiti
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Atherosclerosis, Diabetes
Strategies for Inflammation and Cardiovascular Disease (CVD) Prevention
The long-term goal of the proposed research is to identify and develop effective interventions to decrease persistent, low-level inflammation and risk of CVD.
- Trial name
- SICVDP (NCT02165228)
- Testing
- Mindfulness-based stress reduction, Nutrition Enhancement
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Montana State University
Colonoscopy Pain
Pre-procedural Risk Score-Based Endoscopist Assignment for Pain Reduction in Unsedated Colonoscopy
This multicenter randomized controlled trial evaluates whether a pre-procedural risk score-based endoscopist assignment strategy reduces intraprocedural pain in high-risk patients undergoing unsedated colonoscopy.
- Trial name
- NCT07713953
- Testing
- Risk Score-Based Endoscopist Assignment
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Type 2 Diabetes, Food Insecurity
The Food for Health Study
The project, called Food for Health (F4H), will study a new Produce Prescription Program (PPP) designed for rural Native American older adults.
- Conditions
- Type 2 Diabetes, Food Insecurity, Rural Health
- Trial name
- F4H (NCT07254689)
- Testing
- Produce Prescription Program
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Montana
HIV Risk Behaviors
Sustainable HIV Risk Reduction Strategies for CJ Systems
The purpose of the Texas Christian University (TCU) Disease Risk Reduction (DRR) Project is to develop and test an intervention designed to increase positive decision-making skills among offenders for healthy living, including…
- Trial name
- DRR (NCT01900210)
- Testing
- WaySafe
- Volunteers
- 1,396 people, healthy volunteers welcome
- Sponsor
- Wayne Lehman
Behavior and Behavior Mechanisms
A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents
The purpose of this study is to test the feasibility and efficacy of a triadic intervention designed to target both healthcare providers and parents in order to prevent adolescent sexual risk behavior in Latino and African…
- Trial name
- NCT01326806
- Testing
- Families Talking Together, Active Control on Hygiene & Nutrition
- Where
- United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- New York University
Sugar Sweetened Beverage Consumption, Nutrition
Testing Message Modality of Culturally Appropriate Nutrition Communication for Mexican American Women
A randomized controlled trial to test the effects of culturally appropriate nutrition communication delivered via different modalities for Mexican American women.
- Conditions
- Sugar Sweetened Beverage Consumption, Nutrition, Lifestyle-related Condition, Lifestyle Risk Reduction
- Trial name
- NCT04710108
- Testing
- Health Communication
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of California, Merced
Hiv, HIV Infections
Personalized Prevention for Couples: A 16-month Digital RCT
This couples-based, digital health intervention project is serostatus neutral and seeks to determine efficacy for: a) use and adherence to evidence-based HIV/STI prevention-care strategies; b) creation and adherence to a tailored…
- Conditions
- Hiv, HIV Infections, Sexually Transmitted Infection, Sexually Transmitted Diseases
- Trial name
- LuvHub (NCT05708014)
- Testing
- Intervention LuvHub, Waitlist Control LuvHub
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Florida International University
Cancer, Cardiovascular Diseases
ActivityChoice: Implementing Clinic-Based Physical Activity Program Choices for Cancer Survivors
Cardiovascular disease, the number one leading cause of death in the United States, is highly prevalent in cancer survivors. Physical activity can reduce risk, and referrals to programs addressing survivors' choices are highly…
- Conditions
- Cancer, Cardiovascular Diseases, Physical Inactivity
- Trial name
- NCT05870176
- Testing
- Enhanced Referral, Standard Referral
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Worksite Health Promotion, Lifestyle Risk Reduction
Intervention to Increase Physical Activity and Wellbeing Among Staff and Residents in Assisted Living Facilities
The purpose of the study is to test a program that aims to help staff increase wellness behaviors and test the impact of this program on staff and work outcomes.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Occupational Burnout, Healthcare Workers
- Trial name
- WHHIP+FFC 2026 (NCT07785947)
- Testing
- WHHIP, FFC
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Sexual Violence
Efficacy of a Web-based Sexual Violence Risk Reduction Program for Female College Students
This study evaluates the efficacy of a web-based program for female college freshmen ("RealConsent") in reducing their risk of sexual violence victimization.
- Trial name
- RealConsent (NCT03726437)
- Testing
- RealConsent, Stress and Mood Management
- Where
- United States
- Volunteers
- 881 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Overall Wellness
Increase Surveillance for Wellness Decisions, Also to Determine Targeted Risk-reducing and Preventative Strategies
Healthcare Decisions Post-Testing On Risk Reducing, and Preventative Strategies Utilizing Wellness Lab Tests
- Trial name
- NCT03322241
- Testing
- overall wellness
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Data Collection Analysis Business Management
Cardiovascular Risk Reduction of Having a Coronary Event
A Novel Approach to Cardiovascular Health by Optimizing Risk Management (ANCHOR)
Study Purpose and Design The goal of this study is to improve CVD risk in a primary care adult population, with the following primary objectives 1.
- Trial name
- ANCHOR (NCT01620996)
- Testing
- Minimal Intervention, Motivational Interviewing, Motivational Enhancement
- Where
- Canada
- Volunteers
- 1,708 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Endometrium Cancer
Risk Evaluation and Screening to Tailor Prevention and Reduce the Incidence of Endometrial Cancer
This study proposes to assess feasibility and acceptability of screening and risk reducing interventions in individuals at increased for endometrial cancer (EC).
- Trial name
- RESToRE (NCT05651282)
- Testing
- Provera
- Where
- Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Extreme Heat, Heat Health
Study to Assess the Effectiveness of a Heat Risk Reduction Decision Support Platform and the Barriers and Facilitators of Its Implementation With 30 US Local Health Department Sites
The goal of this clinical trial is to learn if an innovative online decision support tool (Chart) that provides localized health risk assessment for extreme heat at the census tract level helps local health departments plan and…
- Conditions
- Extreme Heat, Heat Health, Extreme Heat Waves, Heat
- Trial name
- NCT06971978
- Testing
- Online decision support platform to support evidence-based heat health risk assessment and extreme heat event preparedness planning, Heat and health risk assessment and preparedness information
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Washington
Addiction, Addiction, Alcohol
The Efficacy of a Mobile Application in Reducing Craving and Lapse Risk in Alcohol and Stimulants Problematic Use
The aim of the study is to evaluate the effectiveness of long-term and short-term app-based self-guided psychological interventions to reduce craving and lapse risk in users with substance use disorder or problematic substance…
- Conditions
- Addiction, Addiction, Alcohol, Addiction, Substance
- Trial name
- NCT05434416
- Testing
- mobile app
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- PredictWatch