Clinical trials: Scarred Uterus
Infertility Due to Nonimplantation, Infertility Secondary
Inflammation Markers in Fluid Aspirate From a Scarred Uterine vs. a Normal Uterine Cavity
A prospective study that will take place in the hydrosonography clinic, comparing patients with an intact uterus to those who had a caesarean section.
- Conditions
- Infertility Due to Nonimplantation, Infertility Secondary, Cesarean Section Complications
- Trial name
- NCT06322498
- Testing
- Uterine lavage
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Uterine Scar
Assessment of Single and Double Layer Suturation of Lower Segment Uterine Incision by USG After C/S
After 6 months of cesarean delivery, the investigators will compare uterine incision scar defects of single and double layer suturation of uterine incision by transvaginal ultrasonography.
- Trial name
- NCT03676907
- Testing
- double layer suturation technique
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gazi University
Uterine Fibroids, Infertility
a Study to Evaluate Adhesion Risk in Fertility Patients' Status Post Laparoscopic Myomectomy.
Premenopausal Women ages 18-42 will undergo a laparoscopic myomectomy. Prior to the myomectomy, adhesions will be assessed using a modified AFS scoring technique.
- Trial name
- VLocmyo (NCT01971060)
- Testing
- surgery utilizing V-Loc suture
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Advanced Gynecologic Surgery Institute
Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness
Impact of Uterine Closure Techniques on the Cesarean Scar Thickness After Repeated Cesarean Section
We compares two techniques of uterine closure on myometrium thickness at the site of uterine scar of women who underwent repeated cesarean section.
- Conditions
- Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness, Cesarean, Residual Myometrial Thickness, Cesarean Section Complications
- Trial name
- NCT03644433
- Testing
- Single layer closure, Double layer closure after resection uterine scar
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Infertile Patients With Previous Live Birth
The Outcome and Influence Factors of Assisted Reproductive Therapy in Patients With Cesarean Scar Uterus.
Mode of delivery affects the success rate of assisted reproductive techniques (ART). In this case study, the investigators will evaluate changes in the bacterial ecology and inflammatory markers of the female uterus with…
- Trial name
- NCT04070222
- Testing
- Hysteroscopy
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Infertility, Asherman's Syndrome
Platelet-rich Plasma (PRP) for Endometrial Regeneration and Repair
Patients with intrauterine adhesions (Asherman's Syndrome) and persistent thin endometrial lining in in vitro fertilization (IVF) treatment programs, particularly those resistant to standard therapies, present a significant…
- Trial name
- PRP-E (NCT02825849)
- Testing
- Intrauterine infusion of platelet rich plasma
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Scarred Uterus
Abnormal Placenta Plant Disease Early Diagnosis and Individualized Treatment Research
As the "two-child" policy implementation, caesarean women's clinical pregnancy is a huge problem again, Especially the placenta planting abnormal disease is a serious threat to the maternal health and life.
- Trial name
- NCT02946749
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Shanghai First Maternity and Infant Hospital
Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy
Birth Cohort Study of China Medical University
The CMUBCS is a birth cohort study located in Shenyang, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology.
- Conditions
- Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy, Scarred Uterus, Overweight and Obesity
- Trial name
- NCT03561766
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Cesarean Section Complications, Cesarean Wound Disruption
Cesarean Scar Defect Formation After First Cesarean Section.
This study is a prospective observational study which will monitor how cesarean section in the first pregnancy will develop a cesarean scar defect.
- Conditions
- Cesarean Section Complications, Cesarean Wound Disruption, Cesarean Wound; Dehiscence
- Trial name
- NCT03966001
- Testing
- Transvaginal sonography at six months after cesarean section, Transvaginal sonography at twelve months after cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Uludag University
Fluid Uterus
Intracavitary Fluid and Position of C-section-scar
Does the presence of intracavitary fluid during hormonal stimulation for IVF depends on the position of C-section-scar ?
- Trial name
- NCT03518385
- Testing
- ultrasound,transvaginal scan
- Where
- United Arab Emirates
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Recurrent Miscarriage
3D Ultrasound to Assess in Recurrent Miscarriage
This observational study aims to compare the prevalence of acquired abnormalities of the uterus (fibroids, polyps, intrauterine adhesions, adenomyosis) in women who have recurrent miscarriages with the fertile population.
- Trial name
- 3D-ARM (NCT06164015)
- Testing
- 3D Ultrasound scan with power Doppler angiography
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Pregnancy Related
Cesarean 123 Trial: Randomized Trial Comparing Single, Double and Triple Layer Uterine Closures During Cesarean Delivery
The goal of this clinical trial is to compare post-operative uterine scar thickness in people who have had the uterus closed during cesarean sections by one of three different methods.
- Trial name
- C123T (NCT05750394)
- Testing
- Uterine layers closed, Suture Type, Endometrium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cesarean Section Complications
Vasopressin vs. Uterine Artery Clamping for Laparoscopic Cesarean Scar Niche Repair
This study evaluates two methods for controlling intraoperative bleeding during laparoscopic surgery to repair a cesarean scar niche (CSN).
- Trial name
- NCT07446933
- Testing
- Vasopressin Group, Bulldog Clamping Group, Standard of Care
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Isthmocele, Uterine Scar Defects
Cesarean Scar Defects After Uterine Closure by Double-layer Barbed or Smooth Suture
Late sequelae of a cesarean section related to a uterine scar defects include gynecological symptoms and obstetric complications.
- Conditions
- Isthmocele, Uterine Scar Defects, Cesarean Section Complications, Uterine Niche
- Trial name
- NCT04825821
- Testing
- Clinical and ultrasonographic assessment
- Where
- Italy
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Ospedale Policlinico San Martino
Myometrial Remodeling
Ultrasound Study of the Uterine Healing Process After Cesarean Delivery
Our hypothesis is that there is no difference in the healing process in those women who have a one- or two-layer uterine closure at the time of cesarean delivery.
- Trial name
- NCT00224250
- Testing
- One- versus two-layer hysterotomy closure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yale University
Niche
Niche In CEsarean Scar Trial (NICEST)
Rationale: Cesarean delivery (CD) rates are increasing rapidly worldwide. The consequences of cesarean section not only affect the next pregnancies such as uterine rupture or malplacentation but also cause many gynecological…
- Trial name
- NCT05312775
- Testing
- Double-layer uterine closure, Single-layer uterine closure
- Where
- Vietnam
- Volunteers
- 938 people, healthy volunteers welcome
- Sponsor
- Nguyen Thi Thu Ha
Minor Intra-uterine Abnormalities
The Impact of Treating Minor Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy in Unselected In Vitro Fertilization (IVF) Cases
This is a comparative, controlled trial to evaluate the impact of treating undetected, asymptomatic, predefined minor uterine cavity abnormalities on the success of IVF treatment.
- Trial name
- NCT00830401
- Testing
- Treatment of predefined abnormality by hysteroscopic surgery, Ofloxacinum/Doxycycline
- Where
- Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Uterine Scar Defect
Double-layer Versus Purse Uterine Closure Techniques : Impact on Residual Myometrial Thickness After Cesarean
There are different surgical techniques of uterine closure during cesarean. Currently data suggest that the double layer unlocked closure technique is associated with better uterine scar healing, and this technique is considered…
- Trial name
- NCT04871022
- Testing
- Double layer closure of the hysterotomy, Purse closure of the hysterotomy
- Where
- Tunisia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Uterine Scar From Previous Cesarean Delivery (Diagnosis)
Uterine Niche After Cesarean Section
In the past decade several articles have described a defect that can be seen on ultrasound at the site of cesarean delivery scar, known as a 'niche' .An incompletely healed scar is a long-term complication of cesarean delivery…
- Trial name
- AMSRM (NCT03787381)
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Cesarean Section Complications
Surgical Management of Cesarean Scar Ectopic Pregnancy: Hysteroscopy & Laparoscopy Outcomes
The study investigates the feasibility, safety, and outcomes of a simultaneous surgical approach for cesarean scar ectopic pregnancy (CSEP). CSEP is a prevalent and serious form of ectopic pregnancy requiring swift intervention.
- Trial name
- NCT07095647
- Testing
- Hysteroscopy
- Where
- Egypt
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Benha University