Clinical trials: Schizophrenia and Disorders With Psychotic Features
Psychosis, Exergaming
Study on the Use of Exergames to Support Older Adults With Psychosis
This study aims to explore a new, engaging approach to support older adults with psychosis-an umbrella term that includes conditions such as schizophrenia, late-onset schizophrenia, and psychotic symptoms resulting from other…
- Conditions
- Psychosis, Exergaming, Elderly
- Trial name
- NCT07060742
- Testing
- Dividat Senso, OTAGO Falls-prevention program
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Tobias Melcher
Schizophrenia
A Study Of Adjunctive Treatment Of Cognitive Deficits In Schizophrenia
The objective of this study is to evaluate the safety, tolerability, and efficacy of two dose regimens of PF-3463275 compared with placebo added to ongoing atypical antipsychotic therapy for cognitive deficits in subjects with…
- Trial name
- NCT00567203
- Testing
- PF-3463275
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Pfizer
Treatment Compliance, Social Media
TTM-Based Social Media Psychoeducation for Psychosis
This doctoral research investigates the effect of a Transtheoretical Model (TTM)-based psychoeducation program delivered via social media on treatment adherence in individuals diagnosed with psychosis.
- Conditions
- Treatment Compliance, Social Media, Psychotic Disorders
- Trial name
- TAPS (NCT07080827)
- Testing
- TTM-Based Online Psychoeducation Program, Standard Face-to-Face Psychoeducation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Psychosis, Cannabis Use
Probing the Cannabinoid System in Individuals With a Family History of Psychosis
The overall purpose of this study is to determine whether a family history of psychosis is associated with an altered cannabinoid system.
- Conditions
- Psychosis, Cannabis Use, THC, Marijuana
- Trial name
- NCT02102113
- Testing
- Very Low Dose THC, Low Dose THC
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia, Psychotic Disorders
Tocilizumab in Schizophrenia
This study is a Phase 1 clinical trial to determine the safety, tolerability, and efficacy of Tocilizumab (Actemra) as an adjunct to antipsychotic medications in stable outpatients with schizophrenia.
- Trial name
- NCT02874573
- Testing
- Tocilizumab, Normal saline
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brian Miller
Schizophrenia, Schizoaffective Disorder
Cognitive Remediation Therapy Within a Secure Forensic Setting
This clinical trial tests the feasibility, effectiveness and patient satisfaction with cognitive remediation therapy for patients diagnosed with schizophrenia or schizoaffective disorder within a forensic hospital.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Cognitive Deficits
- Trial name
- NCT02360813
- Testing
- Cognitive Remediation Therapy, Treatment as usual
- Where
- Ireland
- Volunteers
- 65 people
- Sponsor
- Central Mental Hospital
Schizophrenia
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Brexpiprazole for Extended-Release Injection in Subjects With Schizophrenia
This study is to evaluate the pharmacokinetics (PK), safety and tolerability of Brexpiprazole, administered subcutaneously, in subjects with schizophrenia.
- Trial name
- NCT07742280
- Testing
- Brexpiprazole for ER injection, 45 mg, Brexpiprazole for ER injection, 100 mg
- Volunteers
- 16 people
- Sponsor
- Bostal Drug Delivery Co., Ltd
Audio Visual Hallucinations, Neurofeedback
Rt-fMRI Neurofeedback and AH in Schizophrenia
Auditory hallucinations in schizophrenia are one of the major symptoms of this disease and a major source of psychological discomfort. They are often difficult or impossible to treat with existing methods.
- Conditions
- Audio Visual Hallucinations, Neurofeedback, Schizophrenia, Superior Temporal Gyrus
- Trial name
- NCT03504579
- Testing
- rt-fMRI neurofeedback
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Psychotic Disorders, Cannabis Use Disorder
RCT Comparing Avatar Intervention to Supportive Intervention to Reduce Cannabis Use in Patients With Psychotic Disorders
The goal of this clinical trial is to conduct a single-blind randomized controlled trial to verify whether the Avatar Intervention has greater efficacy over supportive intervention to reduce cannabis use in patients with…
- Conditions
- Psychotic Disorders, Cannabis Use Disorder, Mental Health Disorder
- Trial name
- AC2 (NCT05704582)
- Testing
- Avatar Intervention, Addiction supportive intervention
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Schizophrenia
Oculomotor and Spatial Cognition Deficits in Schizophrenia
DESCRIPTION: (Verbatim from the Applicant's Abstract) Abnormalities of eye movement control and spatial cognition are well-established deficits in schizophrenia.
- Trial name
- NCT00931996
- Testing
- Antipsychotic
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Schizophrenia
Pharmacokinetics and Safety Studies of Esomeprazole Use in Schizophrenia Patients
To evaluate the pharmacokinetic and safety for the esomeprazole use for schizophrenia
- Trial name
- NCT03333603
- Testing
- esomeprazole
- Where
- 2 sites in Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
Schizophrenia Spectrum and Other Psychotic Disorders, Affective Psychoses
SloMo2: Implementation, Effectiveness, and Cost-effectiveness Study
Worries about harm from others (also known as paranoia) are common. Thinking fast or going on gut feelings is natural but can fuel these worries. For some, fast thinking and worries start to get in the way of life.
- Trial name
- NCT06568081
- Testing
- SloMo
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- King's College London
Impaired Cognition, Schizophrenia
A Double-blind, Placebo-controlled Trial of Donepezil Adjunctive Treatment for Cognitive Impairment in Schizophrenia
The objective of the study was to study the effects of donepezil on cognition in patients with schizophrenia. The investigators conducted a 12-week, double-blind, placebo-controlled trial of donepezil as adjunctive treatment to…
- Trial name
- NCT01490567
- Testing
- Donepezil
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Central South University
Schizophrenia
Links Between Perception of Temporal Order Judgment and Causality in Schizophrenia
People with schizophrenia show disturbances in the perception of time. Among these alterations are the perturbations of the temporal order judgment.
- Trial name
- TOCAS (NCT03432000)
- Testing
- Performances of patients and controls on temporal task
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Schizophrenia, Schizoaffective Disorder
Luteolin for the Treatment of People With Schizophrenia
Luteolin is a natural product found in foods such as celery, green pepper, parsley, and chamomile tea. It has been found to have anti-cancer, anti-oxidant, and anti-inflammatory properties.
- Trial name
- NCT05204407
- Testing
- Luteolin
- Where
- 2 sites in United States
- Volunteers
- 85 people
- Sponsor
- University of Maryland, Baltimore
Schizophrenia
Neuromodulation for Schizophrenia
Our proposed study employs a novel approach to determine the clinical and functional imaging effects of brainstem neuromodulation, with an investigational study device, on illness awareness in schizophrenia - a significant…
- Trial name
- NCT05580211
- Testing
- Non-invasive brainstem modulation device (stimulation Randomized), Non-invasive brainstem modulation device (stimulation-Open Label)
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Scion NeuroStim
Tobacco Smoking
E-cigarettes to Promote Smoking Reduction Among Individuals With Schizophrenia
The purpose of this study is to assess if access to an electronic nicotine delivery device, or e-cigarette, in addition to nicotine patch (21 mg) can help reduce cigarette smoking among individuals diagnosed with schizophrenia…
- Trial name
- NCT02918630
- Testing
- Nicotine Patch, E-cigarette
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The University of Texas Health Science Center, Houston
Schizophrenia
Magnetic Seizure Therapy Versus Electroconvulsive Therapy for Schizophrenia
This trial attempts to evaluate the treatment efficacy of magnetic seizure therapy (MST) and its safety among schizophrenia patients.
- Trial name
- NCT03007628
- Testing
- Magpro X100, ThymatronSystem Ⅳ Electroconvulsive System, Treatment as usual (TAU)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Mental Health Center
Waist Circumference Measurements, Schizophrenia
Waist Circumference Measurements in Schizophrenic Patients
The prevalence of metabolic syndrome(MS) among pt's with schizophrenia has been reported to be high, ranging from 24 to 43% in males and 27 to 52% in females.
- Conditions
- Waist Circumference Measurements, Schizophrenia, Cardiovascular Risk Factor
- Trial name
- NCT01243034
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Changhua Christian Hospital
Comparing Hospitalisation Time With Seroquel and Seroquel Prolong
Nis Register Study Comparing Seroquel and Seroquel Prolong
The general aim of this non interventional study is to clarify what are the current clinical treatment practices of Quetiapine Immediate Release and Quetiapine Extended Release.
- Trial name
- NCT00965536
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- AstraZeneca
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