Clinical trials: Scintigraphy Quantification
Scintigraphy Quantification
Absolute Quantification in Bone Scintigraphy
While absolute quantification in 18F-FDG PET (Positon Emission Tomography) is widely used in clinical routine, absolute quantification in SPECT (Single Photon Emission Computed Tomography) is under development and its clinical…
- Trial name
- QUANTOSS-3D (NCT04671238)
- Testing
- SPECT CT
- Where
- 3 sites in France
- Volunteers
- 21 people
- Sponsor
- Central Hospital, Nancy, France
Pseudoarthrosis of Bone
SPECT/CT Bone Scan Quantification Surgery
The hypothesis of our study is that SPECT/CT bone scan fixation quantified by SUVMAX on a CZT solid state camera preoperatively would identify good responders to lumbar arthrodesis surgery.
- Trial name
- PERQUAL (NCT05183542)
- Testing
- Bone scan
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Central Hospital, Nancy, France
Hemodialysis, Coagulation
Dialysis Performance of Different Dialyzer Membranes Using Different Coagulation Strategies
Coagulation within the dialyzer membrane fibres is an obvious biological sign of bio-incompatibility. To avoid clotting during extracorporeal treatment, an anticoagulant is added to the circuit, resulting in an increased risk for…
- Trial name
- NCT03820401
- Testing
- choice of dialyzer, choice of dialysis mode, choice of anticoagulation strategy
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Ghent
Hypo or Hyperthyroidism
Thyroid Uptake Quantification Validation on a Three-dimensional (3D) Cadmium-Zinc-Telluride (CZT) New Generation Gamma Camera
Thyroid scintigraphy using technetium-99m (99mTc) pertechnetate is traditionally performed using planar imaging to estimate thyroid uptake.
- Trial name
- QThy2Dvc3D (NCT07610460)
- Testing
- No Intervention: Observational Cohort
- Where
- Monaco
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Princesse Grace
Healthy Volunteers, Alzheimer Disease
I2PETHV - Imidazoline2 Binding Site in Healthy Volunteers
The imdazoline2 binding site (I2BS) is known to reside inside astrocytes. Changes in the numbers of I2BS in post mortem tissue has implicated them in a range of psychiatric conditions such as depression and addiction, along with…
- Conditions
- Healthy Volunteers, Alzheimer Disease, Molecular Imaging
- Trial name
- I2PETHV (NCT02323217)
- Testing
- [11C]BU99008, Idazoxan, Isocarboxazid
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pectus Excavatum
Three-dimensional Optical Surface Imaging as a Diagnostic Tool in Pectus Excavatum
Pectus excavatum (PE) is the most common anterior chest wall deformity. Currently, a chest radiography (CR) or Computed Tomography (CT) scan is acquired to determine and objectify pectus severity using the Haller Index.
- Trial name
- 3D PECTUS (NCT03926078)
- Testing
- 3D optical surface image, Chest radiography, CT scan
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Advanced Cancers
Quantitation of Left Ventricular Ejection Fraction as Part of F-18 FDG Whole Body PET/CT Scans For Tumor Staging
Primary Objective: Evaluate the agreement between radionuclide ventriculography (RNV) and gated F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in calculating left ventricular ejection…
- Trial name
- NCT00499382
- Testing
- Nuclear Medicine Cardiac Scan, PET/CT Cardiac Scan
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- M.D. Anderson Cancer Center
Metabolism, Fatty Liver
Growth Hormone During Fasting.Signaltransduktion in Muscle and Adipose Tissue and Changes in Intrahepatic Lipid Content
The purpose of this study is to examine the effects of growth hormone during fasting in healthy lean men.
- Trial name
- NCT00476879
- Testing
- Somatropin and pegvisomant
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Coronary Artery Disease
xSPECT-based Myocardial Perfusion Scintigraphy: Consistency of Functional Values and Feasibility of Myocardial Uptake Quantitation in Patients With Suspected Coronary Artery Disease
This study is to evaluate the feasibility of myocardial Standardized Uptake Volume (SUV) assessment by means of X- (Single photon emission tomography) SPECT/Computed tomography (CT), to assess normal reference value under rest…
- Trial name
- xSPECT MPI (NCT04583787)
- Testing
- 99mTc-sestamibi myocardial perfusion SPECT, 82Rb-Chloride myocardial perfusion PET with CCTA
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- University Hospital, Basel, Switzerland
Alzheimer Disease
I2PETPG - Imidazoline2 Binding Sites in a Group of Participants Diagnosed With AD
The imdazoline2 binding site (I2BS) is known to reside inside astrocytes. Changes in the numbers of I2BS in post mortem tissue has implicated them in a range of psychiatric conditions such as depression and addiction, along with…
- Trial name
- I2PETPG (NCT02874820)
- Testing
- [11C]BU99008, Idazoxan
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Imperial College London
Prostate Cancer
Prognostic Value of SPECT-CT Quantitative Indices for the Response Assessment of Bone Metastatic Prostate Carcinoma
Prognostic interest of bone scintigraphy in bone metastatic prostate carcinoma (BMPC) has been shown. Recent technological advances allow to perform quantitative bone SPECT-CT in routine practice.
- Trial name
- INTEVOPROSTATE (NCT03382522)
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Brest
Quantitative Analysis of SPECT MPI
Single-scan Rest/Stress Imaging With Cadmium Zinc Telluride-based SPECT for Coronary Flow Quantification
The investigators aim to address this issue with novel image quantification methods using CZT-based SPECT, which is capable of dynamic data acquisition and therefore feasible for the quantification of the coronary flow.
- Trial name
- NCT02985931
- Testing
- Diagnostic imaging scans of SPECT and MRI
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Alzheimer's Disease
Topography Staging and Dual Phase Image Quantification of Tau PET in Cognitive Impairment Subjects
A second-generation tau PET image tracer 18F-PM-PBB3 (APN-1607 or MNI-958) has been developed by National Institute of Radiological Sciences. The new tracer solved the off-target binding issue.
- Trial name
- NCT04169126
- Testing
- F-18 PMPBB3
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Parkinson´s Disease, Acetylcholine
Quantification of Cerebral Cholinergic Function in Parkinson´s Disease by Means of Nuclear Medicine Methods
Parkinson´s disease is based on a Lewy body degeneration of cerebral and extracerebral neurons. This Lewy body degeneration includes cerebral cholinergic neurons besides dopaminergic neurons.
- Conditions
- Parkinson´s Disease, Acetylcholine, SPECT
- Trial name
- NCT01003535
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Universität des Saarlandes
Breast Cancer, Cardiovascular Diseases
Automated Quantification of Coronary Artery Calcifications on Radiotherapy Planning CTs for Cardiovascular Risk Prediction in Breast Cancer Patients: the BRAGATSTON Study
The aim of the BRAGATSTON study is to provide a low cost tool for measuring CAC in breast cancer patients, thereby identifying patients at increased risk of CVD.
- Trial name
- NCT03206333
- Where
- 3 sites in Netherlands
- Volunteers
- 16,000 people
- Sponsor
- UMC Utrecht
Bone Scintigraphy and Knee Arthroplasty
Bone Scintigraphy and Unicompartimental Knee Arthroplasty
Study the potential interest of bone scintigraphy for patients undergoing unicompartmental knee arthroplasty
- Trial name
- PUC-INTEVO (NCT03145090)
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Thyroid Diseases, Heart Diseases
Interest of the SPECT-CT Scan SUVspect in the New Generation of Gamma-cameras With Semiconductor
Since 2017, a revolution began in the departments of nuclear medicine, with the routine use of gamma-cameras with semiconductor.
- Conditions
- Thyroid Diseases, Heart Diseases, Bone Diseases, Brain Diseases
- Trial name
- GAMMA-CAM (NCT03414021)
- Testing
- SPECT-CT Scan
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- Lille Catholic University