Clinical trials: Sensitivity
Eosinophilic Gastroenteritis, Eosinophilic Esophagitis
Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders
Background: Food allergies are characterized by abnormal immune system responses to certain foods, such as peanuts, strawberries, and shellfish.
- Trial name
- NCT01212016
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Allergic Conjunctivitis
The Role of Vitamin D in Corneal Epithelial Barrier Function, Ocular Microbiome, Ocular Inflammation, and Visual Acuity of Children With Allergic Conjunctivitis
A double-blind study to evaluate the role of vitamin D in corneal epithelial barrier function, ocular microbiome, ocular inflammation, and visual acuity of children with allergic conjunctivitis.
- Trial name
- NCT05839938
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Healthy, Allergy
Normal Values of Facial Thermography
An objective of this study is to standardize temperature values derived from thermograms of the facial region. It is anticipated that the mean temperature of a defined region of interest, such as the eyes, nose, or sinuses, might…
- Conditions
- Healthy, Allergy, Allergic Rhinoconjunctivitis
- Trial name
- NCT00411606
- Testing
- Thermography
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- West Penn Allegheny Health System
Atopic Dermatitis, Serum Skin Test
Autologous Serum Skin Testing in Patients With Atopic Dermatitis Autologous Serum Skin Testing in Patients With Atopic Dermatitis
Recently, IgE-type autoantibodies against self proteins have been detected in the serum of the atopic dermatitis patients. The role of this IgE autoantibodies involved in the pathogenesis of atopic dermatitis is not known, yet.
- Trial name
- NCT01238263
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Distal Radius Fracture
Evaluating Validity of Ultrasonography in Determining Distal Radius Fracture Reduction
The purpose of this study is to evaluate whether ultrasonography guidance compare with the simple radiography aids in determining the adequacy of distal radius fracture reduction.
- Trial name
- NCT01823692
- Testing
- ultrasonography
- Where
- Iran
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Postoperative Sensitivity, Rebound Pain
Menstrual Cycle Effects on Postoperative Sensitivity and Rebound Pain in Composite Restorations
This study aims to evaluate how different phases of the menstrual cycle affect pain after dental treatments. Specifically, it investigates two types of pain: Postoperative sensitivity (pain felt after the filling procedure), and…
- Conditions
- Postoperative Sensitivity, Rebound Pain, Menstrual Cycle, Composite Restorations
- Trial name
- NCT06886243
- Testing
- Direct Posterior Composite Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Firat University
Dentin Sensitivity
Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
This single center, comparative design study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a…
- Trial name
- NCT02832375
- Testing
- stannous fluoride, sodium monofluorophosphate
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Allergic Conjunctivitis
Safety and Comfort of AL-4943A Ophthalmic Solution
The purpose of this study is to assess the ocular comfort and safety of olopatadine hydrochloride opthalmic solution. 0.7%.
- Trial name
- NCT01326858
- Testing
- Olopatadine hydrochloride ophthalmic solution, 0.7%, Olopatadine hydrochloride ophthalmic solution vehicle, Ketotifen fumarate ophthalmic solution, 0.025%
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Glaucoma Diagnosis
How Accurately Does the Diopsys Visual Evoked Potential (VEP) Vision Testing System Detect Glaucoma?
Evaluate sensitivity and specificity of NOVA-DN visually evoked potentials (VEP) protocol and new software method (Corda) for glaucoma detection using optical coherence tomography (OCT) images to differentiate between normal…
- Trial name
- NCT02622178
- Testing
- Optical Coherence Tomography, Visual evoked potential
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Allergy
To Demonstrate the Relative Bioavailability Study of Promethazine HCl 50 mg Tablets Under Fasting Conditions
To demonstrate the relative bioavailability study of Promethazine HCl 50 mg tablets under fasting conditions.
- Trial name
- NCT00947063
- Testing
- Promethazine HCl 50 mg Tablets (Sandoz, Inc), Phenergan (Promethazine HCl) 50 mg Tablets (Wyeth Laboratories)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sandoz
Dentin Sensitivity
Comparison of the Effectiveness of Self Etch Adhesive and Fluoride Varnish in Reducing Hypersensitivity in Patients With Gingival Recession
Comparison of the clinical effectiveness of self etch adhesive and fluoride varnish in reducing dentin hypersensitivity in patients with gingival recession.
- Trial name
- NCT05895526
- Testing
- Self etch dentin adhesive, Fluoride varnish
- Where
- Pakistan
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Prime Foundation
Autonomic Nervous System, Baroreflex
Stress and the Nervous System
Models of stress such as hypoglycemia have identified that stress results the next day in decreased baroreflex sensitivity. This project will test the hypothesis that these delayed changes in autonomic nervous system function are…
- Conditions
- Autonomic Nervous System, Baroreflex, Stress, Physiological
- Trial name
- NCT02339506
- Testing
- Cosyntropin
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Atopic Dermatitis
Atopic Dermatitis Research Network (ADRN) Influenza Vaccine Pilot
A new flu vaccine which is injected into the skin instead of into the muscle has recently been approved by the Food and Drug Administration for vaccination of the general population including patients with atopic dermatitis (AD).
- Trial name
- NCT01518478
- Testing
- Fluzone® Intradermal (Sanofi Pasteur Inc.)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sarcoidosis, Influenza Vaccine
Efficacy and Safety of Influenza Vaccine During Sarcoidosis
Sarcoidosis is an inflammatory disease of unknown origin that can affect all organs, especially the lungs and mediastinum. Some location of sarcoidosis may require treatment with corticosteroids or immunosuppressors.Although…
- Trial name
- SARCOVAC (NCT01687517)
- Testing
- Seasonal influenza vaccine available for the 2012-2013 vaccine campaign
- Where
- France
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma, Chronic Obstructive Pulmonary Disease
Study of ARO-MUC5AC in Healthy Subjects and Patients With Muco-Obstructive Lung Disease
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of ARO-MUC5AC in normal healthy volunteers (NHVs), patients with moderate-to-severe asthma and patients with moderate-to-severe chronic…
- Trial name
- NCT05292950
- Testing
- ARO-MUC5AC
- Where
- 13 sites in Australia, New Zealand and 5 more
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Arrowhead Pharmaceuticals
Healthy Adult Participants
Alcohol Sensitivity Among Older Adults Who Consume Alcohol
This is a proof-of-concept study exploring individual differences in sensitivity to alcohol among older healthy current drinkers aged 65 to 80.
- Trial name
- NCT07636447
- Testing
- Alcohol (Oral)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Florida
Chronic Stress, Stool Frequency
Assessing Diet, Stress Scores, and Other Health Metrics in Healthy Northern California Adults
The purpose of this study is to gather health and nutrition data from the population of Davis, CA and surrounding areas. This data will be used to help us test and improve our study procedures for a larger planned study on peanut…
- Conditions
- Chronic Stress, Stool Frequency, Food Allergies, Diet Surveys
- Trial name
- NCT07265648
- Testing
- Online Survey
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Allergies
The Phthalate-Allergen Immune Response Study
Phthalates are commonly used plasticizers that have been linked to asthma in epidemiological studies. The investigators are researching effects of phthalates on airway immunology and lung function, and on allergic responses by…
- Trial name
- PAIR (NCT02688478)
- Testing
- Phthalate, Filtered Air, Allergen
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asthma, Cough
Sensory-Mechanical Responses to Eucapneic Voluntary Hyperventilation and Mannitol
The objectives of this study are to determine the sensory-mechanical responses to Eucapneic Voluntary Hyperventilation (EVH) and Mannitol in individuals with cough variant asthma (CVA) and methacholine-induced cough with normal…
- Conditions
- Asthma, Cough, Cough Variant Asthma
- Trial name
- NCT03105843
- Testing
- Methacholine (MCh) Challenge Testing, Eucapneic Voluntary Hyperventilation (EVH), Mannitol Inhalation Kit
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Dr. Diane Lougheed
Atopic Dermatitis
The Effect of Intervention and Mechanism of ICBT on Chronic Itching in Patients With Atopic Dermatitis
Objectives: The study subjects were 180 healthy people from the dermatology clinic of Xiangya Hospital of Central South University and the surroundingcommunity, including 120 AD patients (60 in the ICBT treatment group and 60 in…
- Trial name
- NCT05502848
- Testing
- Internet Cognitive Behavior Therapy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University